BR112014024057A2 - - Google Patents

Info

Publication number
BR112014024057A2
BR112014024057A2 BR112014024057A BR112014024057A BR112014024057A2 BR 112014024057 A2 BR112014024057 A2 BR 112014024057A2 BR 112014024057 A BR112014024057 A BR 112014024057A BR 112014024057 A BR112014024057 A BR 112014024057A BR 112014024057 A2 BR112014024057 A2 BR 112014024057A2
Authority
BR
Brazil
Application number
BR112014024057A
Other versions
BR112014024057A8 (pt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR112014024057A2 publication Critical patent/BR112014024057A2/pt
Publication of BR112014024057A8 publication Critical patent/BR112014024057A8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/661Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/683Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/395Alveolar surfactant peptides; Pulmonary surfactant peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0082Lung surfactant, artificial mucus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785Alveolar surfactant peptides; Pulmonary surfactant peptides
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
BR112014024057A 2012-03-28 2013-03-28 processo para fabricar um tensoativo pulmonar sintético liofilizado, composição de tensoativo pulmonar sintético liofilizado, e, tensoativo pulmonar sintético liofilizado BR112014024057A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261616827P 2012-03-28 2012-03-28
PCT/US2013/034464 WO2013149074A1 (en) 2012-03-28 2013-03-28 Lyophilization of synthetic liposomal pulmonary surfactant

Publications (2)

Publication Number Publication Date
BR112014024057A2 true BR112014024057A2 (pt) 2017-06-20
BR112014024057A8 BR112014024057A8 (pt) 2018-01-16

Family

ID=48096305

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014024057A BR112014024057A8 (pt) 2012-03-28 2013-03-28 processo para fabricar um tensoativo pulmonar sintético liofilizado, composição de tensoativo pulmonar sintético liofilizado, e, tensoativo pulmonar sintético liofilizado

Country Status (35)

Country Link
US (3) US9554999B2 (pt)
EP (2) EP2723323B1 (pt)
JP (1) JP6178402B2 (pt)
KR (1) KR102123129B1 (pt)
CN (1) CN104271118B (pt)
AU (2) AU2013237985B2 (pt)
BR (1) BR112014024057A8 (pt)
CA (1) CA2867649C (pt)
CL (1) CL2014002553A1 (pt)
CO (1) CO7081146A2 (pt)
CR (1) CR20140449A (pt)
CU (1) CU20140116A7 (pt)
CY (1) CY1117380T1 (pt)
DK (1) DK2723323T3 (pt)
EC (1) ECSP14024363A (pt)
ES (1) ES2557805T3 (pt)
HK (3) HK1197174A1 (pt)
HR (1) HRP20151392T1 (pt)
HU (1) HUE026363T2 (pt)
IL (1) IL234688B (pt)
IN (1) IN2014DN08538A (pt)
MA (1) MA37445B1 (pt)
MX (1) MX359654B (pt)
MY (1) MY164868A (pt)
NZ (1) NZ630219A (pt)
PE (1) PE20142302A1 (pt)
PL (1) PL2723323T3 (pt)
PT (1) PT2723323E (pt)
RS (1) RS54513B1 (pt)
RU (1) RU2671500C2 (pt)
SG (1) SG11201405944PA (pt)
SI (1) SI2723323T1 (pt)
SM (1) SMT201500320B (pt)
WO (2) WO2013149013A1 (pt)
ZA (1) ZA201406982B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS54513B1 (en) * 2012-03-28 2016-06-30 Discovery Laboratories, Inc. LYOPHILIZATION OF SYNTHETIC LIPOSOMAL LUNG SURFACTANT
US9987228B2 (en) * 2014-11-18 2018-06-05 National Institute For Materials Science Method for producing porous particle
WO2016108534A1 (ko) * 2014-12-30 2016-07-07 주식회사 삼양바이오팜 고분자 나노입자 동결건조물 및 그 제조방법
PL3319597T3 (pl) * 2015-07-10 2021-10-11 Byondis B.V. Kompozycje zawierające koniugaty przeciwciało-duokarmycyna
PT3324932T (pt) 2015-07-22 2021-04-06 Nitto Denko Corp Composições e métodos para formas de liófilos de nanopartículas
JP7012512B2 (ja) * 2017-11-13 2022-01-28 清水建設株式会社 管理装置、製造システムおよび管理方法
JP7335263B2 (ja) * 2017-12-21 2023-08-29 キウィタス セラピューティクス,インコーポレイテッド 吸入のための界面活性剤製剤
CN108853061A (zh) * 2018-10-09 2018-11-23 兆科药业(合肥)有限公司 一种人工合成肺表面活性剂药物组合物及与之的肠溶胶囊和其制备方法及用途
WO2020142420A1 (en) * 2018-12-31 2020-07-09 Novus Therapeutics, Inc. Novel surfactant-lipid alloy drug substance, methods of making the same, and pharmaceutical compositions comprising the same
US11287185B1 (en) 2020-09-09 2022-03-29 Stay Fresh Technology, LLC Freeze drying with constant-pressure and constant-temperature phases
KR102545292B1 (ko) * 2021-01-28 2023-06-16 인천대학교 산학협력단 마이크로캡슐 형성용 생체 적합 계면활성제 합성방법
TW202317609A (zh) * 2021-07-05 2023-05-01 義大利商吉斯藥品公司 肺部表面張力素之製備方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE751108R (fr) 1969-06-06 1970-11-03 Berliet Automobiles Dispositif pour la mesure precise de la consommation specifiquedes moteurs a combustion
JPS59164724A (ja) * 1983-03-10 1984-09-17 Tokyo Tanabe Co Ltd サ−フアクタント及びそれを含有する呼吸窮迫症候群治療剤
US5260273A (en) 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
ATE212220T1 (de) 1996-01-24 2002-02-15 Byk Gulden Lomberg Chem Fab Verfahren zur herstellung von pulverförmigen lungensurfactant-zubereitungen
AU2322097A (en) * 1996-03-27 1997-10-17 Ortho Pharmaceutical Corporation Lyophilized pulmonary surfactant peptide compositions
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5855913A (en) 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
US7638493B2 (en) 2004-04-29 2009-12-29 Sannamu Lee Artificial pulmonary surfactant compositions and use of the same
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
EP2377554A1 (en) * 2005-07-22 2011-10-19 Amgen, Inc Concentrated protein lyophilates, methods and uses
EP1997502A1 (en) 2007-06-01 2008-12-03 CHIESI FARMACEUTICI S.p.A. Reconstituted surfactants having improved properties
RS54513B1 (en) * 2012-03-28 2016-06-30 Discovery Laboratories, Inc. LYOPHILIZATION OF SYNTHETIC LIPOSOMAL LUNG SURFACTANT

Also Published As

Publication number Publication date
AU2017239624A1 (en) 2017-10-26
US9554999B2 (en) 2017-01-31
CO7081146A2 (es) 2014-10-10
MA37445B1 (fr) 2017-01-31
EP2723323A1 (en) 2014-04-30
SG11201405944PA (en) 2014-10-30
HK1205685A1 (en) 2015-12-24
ZA201406982B (en) 2016-05-25
HK1206979A1 (en) 2016-01-22
PT2723323E (pt) 2016-01-27
MA37445A1 (fr) 2016-04-29
US20140088026A1 (en) 2014-03-27
DK2723323T3 (en) 2016-01-11
SI2723323T1 (sl) 2016-04-29
US8748397B2 (en) 2014-06-10
MX2014011483A (es) 2014-12-08
ECSP14024363A (es) 2015-09-30
HUE026363T2 (en) 2016-06-28
HK1197174A1 (zh) 2015-01-09
CL2014002553A1 (es) 2015-04-06
NZ630219A (en) 2016-09-30
AU2013237985B2 (en) 2017-07-06
PE20142302A1 (es) 2015-01-21
RS54513B1 (en) 2016-06-30
AU2017239624B2 (en) 2017-11-23
MY164868A (en) 2018-01-30
ES2557805T3 (es) 2016-01-28
MX359654B (es) 2018-10-05
EP2723323B1 (en) 2015-09-23
HRP20151392T1 (hr) 2016-03-25
JP2015514714A (ja) 2015-05-21
US20150297524A1 (en) 2015-10-22
EP2837377A1 (en) 2015-02-18
KR20140137453A (ko) 2014-12-02
PL2723323T3 (pl) 2016-05-31
IL234688A0 (en) 2014-11-30
US20140088025A1 (en) 2014-03-27
WO2013149074A1 (en) 2013-10-03
RU2014143247A (ru) 2016-05-20
IL234688B (en) 2020-01-30
CU20140116A7 (es) 2015-01-29
CA2867649A1 (en) 2013-10-03
AU2013237985A1 (en) 2014-10-02
BR112014024057A8 (pt) 2018-01-16
SMT201500320B (it) 2016-02-25
IN2014DN08538A (pt) 2015-05-15
CN104271118B (zh) 2017-02-08
WO2013149013A1 (en) 2013-10-03
KR102123129B1 (ko) 2020-06-15
CA2867649C (en) 2021-02-16
RU2671500C2 (ru) 2018-11-01
CY1117380T1 (el) 2017-04-26
CR20140449A (es) 2015-05-04
US8748396B2 (en) 2014-06-10
CN104271118A (zh) 2015-01-07
JP6178402B2 (ja) 2017-08-09

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements