BR112014022847A2 - - Google Patents
Info
- Publication number
- BR112014022847A2 BR112014022847A2 BR112014022847A BR112014022847A BR112014022847A2 BR 112014022847 A2 BR112014022847 A2 BR 112014022847A2 BR 112014022847 A BR112014022847 A BR 112014022847A BR 112014022847 A BR112014022847 A BR 112014022847A BR 112014022847 A2 BR112014022847 A2 BR 112014022847A2
- Authority
- BR
- Brazil
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/30—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/185—Saturated compounds having only one carboxyl group and containing keto groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12001793.4 | 2012-03-16 | ||
| EP12001793 | 2012-03-16 | ||
| PCT/EP2013/000699 WO2013135360A1 (en) | 2012-03-16 | 2013-03-11 | Aminoacid lipids |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014022847A2 true BR112014022847A2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2017-06-20 |
| BR112014022847B1 BR112014022847B1 (pt) | 2022-08-23 |
Family
ID=47901939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014022847-7A BR112014022847B1 (pt) | 2012-03-16 | 2013-03-11 | Lipídios aminoácidos, composição vesicular, e kit |
Country Status (21)
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2825156B1 (en) * | 2012-03-16 | 2017-07-26 | Merck Patent GmbH | Targeting aminoacid lipids |
| ES2684527T3 (es) | 2013-02-14 | 2018-10-03 | Nanopareil, Llc | Fieltro híbrido de nanofibras electrohiladas, método de preparación del mismo y método de purificación de biomoléculas |
| EP2971010B1 (en) | 2013-03-14 | 2020-06-10 | ModernaTX, Inc. | Formulation and delivery of modified nucleoside, nucleotide, and nucleic acid compositions |
| US11633355B2 (en) | 2014-12-12 | 2023-04-25 | Clemson University Research Foundation | Multi-functional particles and methods of using the same |
| US10232050B1 (en) | 2014-12-12 | 2019-03-19 | Clemson University | Multi-functional particles and methods of using the same |
| US10343194B2 (en) * | 2015-11-11 | 2019-07-09 | The Yokohama Rubber Co., Ltd. | Tire cleaning system |
| CN106083637B (zh) * | 2016-06-06 | 2018-11-23 | 大连民族大学 | 味精类脂、味精脂质体的合成方法及其应用 |
| KR102358341B1 (ko) * | 2016-06-24 | 2022-02-07 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 양이온성 지질 |
| WO2018026866A1 (en) * | 2016-08-03 | 2018-02-08 | Neuropore Therapies, Inc. | Lipid-substituted amino 1,2-and 1,3-diol compounds as modulators of tlr2 dimerization |
| WO2019131580A1 (ja) | 2017-12-27 | 2019-07-04 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | カチオン性脂質 |
| BR112021022182A2 (pt) * | 2019-05-07 | 2021-12-21 | Univ Do Minho | Método para produção de lipossomas. |
| CN112010995A (zh) * | 2019-05-30 | 2020-12-01 | 株式会社大赛璐 | 壳聚糖衍生物及光学异构体用分离剂 |
| CN114177136B (zh) * | 2020-09-12 | 2023-08-01 | 苏州优诺康医药科技有限公司 | 一种可注射用的两亲性嵌段共聚物纳米载药胶束 |
| CN113185421B (zh) * | 2020-11-27 | 2022-01-25 | 广州市锐博生物科技有限公司 | 脂质化合物及其组合物 |
| EP4534525A4 (en) * | 2022-06-02 | 2025-08-20 | Xiamen Sinopeg Biotech Co Ltd | CATIONIC LIPID BASED ON AMINO ACIDS CONTAINING UNSATURATED BONDS |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2967069D1 (en) | 1978-01-16 | 1984-08-02 | Univ Boston | Effecting cellular uptake of molecules |
| US4144036A (en) * | 1978-03-27 | 1979-03-13 | Texaco Inc. | Detergent fuel composition |
| US4144034A (en) * | 1978-03-27 | 1979-03-13 | Texaco Inc. | Polyether-maleic anhydride reaction product containing motor fuel composition |
| US5108921A (en) | 1989-04-03 | 1992-04-28 | Purdue Research Foundation | Method for enhanced transmembrane transport of exogenous molecules |
| US6030954A (en) | 1991-09-05 | 2000-02-29 | University Of Connecticut | Targeted delivery of poly- or oligonucleotides to cells |
| US6335434B1 (en) | 1998-06-16 | 2002-01-01 | Isis Pharmaceuticals, Inc., | Nucleosidic and non-nucleosidic folate conjugates |
| IT1254135B (it) | 1992-01-16 | 1995-09-08 | Sigma Tau Ind Farmaceuti | Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica. |
| US6214388B1 (en) | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
| DE19521412A1 (de) * | 1995-06-14 | 1996-12-19 | Boehringer Mannheim Gmbh | Neue kationische und polykationische Amphiphile, diese enthaltende Reagenzien und deren Verwendung |
| US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
| WO1998052614A2 (en) | 1997-05-21 | 1998-11-26 | The Board Of Trustees Of The Leland Stanford Junior University | Composition and method for enhancing transport across biological membranes |
| EP2415486B1 (en) | 2001-05-18 | 2017-02-22 | Sirna Therapeutics, Inc. | Conjugates and compositions for cellular delivery |
| JP5093547B2 (ja) * | 2001-08-24 | 2012-12-12 | 日本ケミカルリサーチ株式会社 | 両イオン性脂質およびその用途 |
| WO2003022910A1 (en) | 2001-09-08 | 2003-03-20 | Access Pharmaceuticals, Inc. | Synthesis and uses of polymer gel nanoparticle networks |
| EP1308167A1 (de) | 2001-11-06 | 2003-05-07 | Pickl, Winfried, Ao. Univ. Prof. Dr. | Antigenpräsentierende Vesikel |
| JP4527407B2 (ja) * | 2002-04-15 | 2010-08-18 | オンコサイレオン インコーポレーテッド | ワクチンとしての合成グリコリポペプチド |
| US7226636B2 (en) * | 2003-07-31 | 2007-06-05 | Los Alamos National Security, Llc | Gold-coated nanoparticles for use in biotechnology applications |
| EP1709195B1 (en) * | 2003-12-19 | 2014-01-22 | Novartis Vaccines and Diagnostics, Inc. | Cell transfecting formulations of small interfering rna, related compositions and methods of making and use |
| US20100028450A1 (en) | 2006-01-25 | 2010-02-04 | The Board Of Trustees Of The University Of Illinoi S | Tolerogenic biodegradable artificial antigen presenting system |
| JP5253716B2 (ja) * | 2006-02-09 | 2013-07-31 | 日本ケミカルリサーチ株式会社 | ｐＨ応答性分子集合体 |
| WO2008062911A1 (fr) * | 2006-11-24 | 2008-05-29 | Waseda University | Réactif pour l'introduction d'une protéine ou d'un gène |
| CN101674853B (zh) * | 2007-05-04 | 2013-03-27 | 玛瑞纳生物技术有限公司 | 氨基酸脂质及其用途 |
| WO2009129387A2 (en) * | 2008-04-16 | 2009-10-22 | Abbott Laboratories | Cationic lipids and uses thereof |
| US20120294924A1 (en) | 2011-04-29 | 2012-11-22 | Thomas Tice | Peptide-Lipid Conjugates And Uses Thereof |
-
2013
- 2013-03-11 JP JP2014561311A patent/JP6457816B2/ja active Active
- 2013-03-11 KR KR1020147028907A patent/KR102081046B1/ko active Active
- 2013-03-11 WO PCT/EP2013/000699 patent/WO2013135360A1/en active Application Filing
- 2013-03-11 PT PT13710787T patent/PT2825157T/pt unknown
- 2013-03-11 MX MX2014010810A patent/MX359736B/es active IP Right Grant
- 2013-03-11 RU RU2014141547A patent/RU2670618C2/ru active
- 2013-03-11 SG SG11201405536YA patent/SG11201405536YA/en unknown
- 2013-03-11 AU AU2013231819A patent/AU2013231819B2/en active Active
- 2013-03-11 BR BR112014022847-7A patent/BR112014022847B1/pt active IP Right Grant
- 2013-03-11 SG SG10201610402VA patent/SG10201610402VA/en unknown
- 2013-03-11 ES ES13710787T patent/ES2700742T3/es active Active
- 2013-03-11 US US14/385,178 patent/US9796666B2/en active Active
- 2013-03-11 SI SI201331279T patent/SI2825157T1/sl unknown
- 2013-03-11 HU HUE13710787A patent/HUE040256T2/hu unknown
- 2013-03-11 EP EP13710787.6A patent/EP2825157B1/en active Active
- 2013-03-11 PL PL13710787T patent/PL2825157T3/pl unknown
- 2013-03-11 DK DK13710787.6T patent/DK2825157T3/da active
- 2013-03-11 CN CN201380013769.0A patent/CN104168887B/zh active Active
- 2013-03-11 CA CA2867184A patent/CA2867184C/en active Active
- 2013-03-11 NZ NZ630990A patent/NZ630990A/en unknown
- 2013-03-15 TW TW102109379A patent/TWI606030B/zh active
-
2014
- 2014-10-15 ZA ZA2014/07491A patent/ZA201407491B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2670618C2 (ru) | 2018-10-24 |
| TWI606030B (zh) | 2017-11-21 |
| CA2867184A1 (en) | 2013-09-19 |
| PT2825157T (pt) | 2018-12-14 |
| JP6457816B2 (ja) | 2019-01-23 |
| ES2700742T3 (es) | 2019-02-19 |
| SG11201405536YA (en) | 2014-10-30 |
| RU2014141547A (ru) | 2016-05-10 |
| AU2013231819B2 (en) | 2017-07-20 |
| DK2825157T3 (da) | 2019-01-02 |
| SG10201610402VA (en) | 2017-02-27 |
| CN104168887B (zh) | 2018-09-04 |
| US9796666B2 (en) | 2017-10-24 |
| CN104168887A (zh) | 2014-11-26 |
| JP2015514692A (ja) | 2015-05-21 |
| KR102081046B1 (ko) | 2020-02-25 |
| WO2013135360A1 (en) | 2013-09-19 |
| NZ630990A (en) | 2016-04-29 |
| TW201343615A (zh) | 2013-11-01 |
| SI2825157T1 (sl) | 2019-01-31 |
| KR20140135832A (ko) | 2014-11-26 |
| HUE040256T2 (hu) | 2019-02-28 |
| US20150030670A1 (en) | 2015-01-29 |
| EP2825157B1 (en) | 2018-09-05 |
| ZA201407491B (en) | 2015-12-23 |
| PL2825157T3 (pl) | 2019-05-31 |
| HK1199819A1 (en) | 2015-07-24 |
| EP2825157A1 (en) | 2015-01-21 |
| CA2867184C (en) | 2020-09-01 |
| BR112014022847B1 (pt) | 2022-08-23 |
| MX2014010810A (es) | 2014-12-08 |
| MX359736B (es) | 2018-10-09 |
| AU2013231819A1 (en) | 2014-10-30 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 11/03/2013, OBSERVADAS AS CONDICOES LEGAIS |