BR112014018179B1 - Vetor de expressão viral, partícula viral, uso dos mesmos, composição, e método in vitro para expressão de um polipeptídeo heterólogo em uma célula - Google Patents

Vetor de expressão viral, partícula viral, uso dos mesmos, composição, e método in vitro para expressão de um polipeptídeo heterólogo em uma célula Download PDF

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BR112014018179B1
BR112014018179B1 BR112014018179-9A BR112014018179A BR112014018179B1 BR 112014018179 B1 BR112014018179 B1 BR 112014018179B1 BR 112014018179 A BR112014018179 A BR 112014018179A BR 112014018179 B1 BR112014018179 B1 BR 112014018179B1
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piv5
virus
mice
gene
influenza
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BR112014018179-9A
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Portuguese (pt)
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BR112014018179A2 (pt
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Biao He
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University Of Georgia Research Foundation, Inc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/12Viral antigens
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
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    • A61K2039/58Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
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    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
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    • C12N2760/18011Paramyxoviridae
    • C12N2760/18711Rubulavirus, e.g. mumps virus, parainfluenza 2,4
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    • C12N2760/18011Paramyxoviridae
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BR112014018179-9A 2012-01-24 2013-01-24 Vetor de expressão viral, partícula viral, uso dos mesmos, composição, e método in vitro para expressão de um polipeptídeo heterólogo em uma célula BR112014018179B1 (pt)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261590070P 2012-01-24 2012-01-24
US201261590056P 2012-01-24 2012-01-24
US61/590,056 2012-01-24
US61/590,070 2012-01-24
US201261683810P 2012-08-16 2012-08-16
US61/683,810 2012-08-16
PCT/US2013/022962 WO2013112720A1 (en) 2012-01-24 2013-01-24 Parainfluenza virus 5 based vaccines

Publications (2)

Publication Number Publication Date
BR112014018179A2 BR112014018179A2 (pt) 2017-07-04
BR112014018179B1 true BR112014018179B1 (pt) 2022-04-12

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BR112014018179-9A BR112014018179B1 (pt) 2012-01-24 2013-01-24 Vetor de expressão viral, partícula viral, uso dos mesmos, composição, e método in vitro para expressão de um polipeptídeo heterólogo em uma célula

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US (6) US9732358B2 (https=)
EP (2) EP2806891B1 (https=)
JP (3) JP6228136B2 (https=)
CN (2) CN104093422B (https=)
AU (1) AU2013212097B2 (https=)
BR (1) BR112014018179B1 (https=)
CA (2) CA3128591A1 (https=)
ES (1) ES2728248T3 (https=)
MX (1) MX359638B (https=)
MY (1) MY173638A (https=)
PH (1) PH12014501255B1 (https=)
PT (1) PT2806891T (https=)
WO (2) WO2013112720A1 (https=)

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ES2728248T3 (es) 2012-01-24 2019-10-23 Univ Georgia Vacunas basadas en el virus paragripal 5
KR101577397B1 (ko) * 2014-01-15 2015-12-28 경북대학교 산학협력단 신규한 돼지 파라인플루엔자 바이러스 5(pPIV5), 이를 포함하는 백신 조성물 및 이를 이용한 돼지 파라인플루엔자 바이러스 검정 키트
CN107847610B (zh) * 2015-04-28 2022-02-01 塞维卡有限责任公司 基于piv5的扩增病毒样颗粒
JPWO2016199936A1 (ja) * 2015-06-12 2018-04-05 国立大学法人三重大学 ヒトパラインフルエンザ2型ウイルスベクター及びワクチン
EP3630144A4 (en) * 2017-05-25 2021-03-31 University of Central Florida Research Foundation, Inc. NEW ONCOLYTIC VIRUSES TO SENSITIZE TUMOR CELLS TO DESTRUCTION BY NATURAL KILLER CELLS
RU2681473C1 (ru) * 2018-01-16 2019-03-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кубанский государственный аграрный университет имени И.Т. Трубилина" Тест-система для обнаружения генома вируса парагриппа 3 типа у крупного рогатого скота с помощью мультиплексной полимеразной цепной реакции с флуоресцентной детекцией в режиме реального времени
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WO2020092207A1 (en) * 2018-10-28 2020-05-07 University Of Georgia Research Foundation Broadly reactive immunogens of influenza virus, compositions, and methods of use thereof
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JP7802064B2 (ja) * 2020-09-21 2026-01-19 ユニバーシティ オブ ジョージア リサーチ ファンデーション,インコーポレーテッド Piv5ベースのcovid-19ワクチン
US20240102912A1 (en) * 2020-11-09 2024-03-28 Thrive Bioscience, Inc. Plaque counting assay method
CN113005149A (zh) * 2021-03-26 2021-06-22 中国农业大学 一种表达冠状病毒受体结合域串联二聚体的重组副流感病毒5型载体
CA3230325A1 (en) * 2021-08-26 2023-03-02 University Of Georgia Research Foundation, Inc. J paramyxovirus vaccines
GB202209861D0 (en) * 2022-07-05 2022-08-17 Univ Court Univ St Andrews Viral vectors
EP4611804A1 (en) * 2022-11-04 2025-09-10 Blue Lake Biotechnology, Inc. Recombinant rsv vaccine: methods of making and using the same
CN121263205A (zh) * 2023-02-06 2026-01-02 塞维卡有限责任公司 修饰的piv5疫苗载体:制造方法和用途
CN116270766A (zh) * 2023-02-23 2023-06-23 天津理工大学 一种副流感病毒5型作为溶瘤病毒在抗肿瘤中的应用
CN117625560B (zh) * 2023-11-03 2025-09-16 中国农业大学 一种重组病毒rPIV5-H3及其制备方法、应用和疫苗

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