BR112014018135A8 - Produto farmacêutico e uso do produto farmacêutico - Google Patents
Produto farmacêutico e uso do produto farmacêuticoInfo
- Publication number
- BR112014018135A8 BR112014018135A8 BR112014018135A BR112014018135A BR112014018135A8 BR 112014018135 A8 BR112014018135 A8 BR 112014018135A8 BR 112014018135 A BR112014018135 A BR 112014018135A BR 112014018135 A BR112014018135 A BR 112014018135A BR 112014018135 A8 BR112014018135 A8 BR 112014018135A8
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical product
- compound
- maximizes
- toxicity
- provision
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261612429P | 2012-03-19 | 2012-03-19 | |
| PCT/EP2013/055324 WO2013139687A1 (en) | 2012-03-19 | 2013-03-15 | Method for administration of an anti tumor agent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112014018135A2 BR112014018135A2 (https=) | 2017-06-20 |
| BR112014018135A8 true BR112014018135A8 (pt) | 2021-10-19 |
Family
ID=47913395
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014018135A BR112014018135A8 (pt) | 2012-03-19 | 2013-03-15 | Produto farmacêutico e uso do produto farmacêutico |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US20130245089A1 (https=) |
| EP (1) | EP2827858B1 (https=) |
| JP (2) | JP6224690B2 (https=) |
| KR (4) | KR102438597B1 (https=) |
| CN (2) | CN104203232A (https=) |
| BR (1) | BR112014018135A8 (https=) |
| CA (1) | CA2859940C (https=) |
| CY (1) | CY1118070T1 (https=) |
| DK (1) | DK2827858T3 (https=) |
| ES (1) | ES2593066T3 (https=) |
| HK (1) | HK1204934A1 (https=) |
| HR (1) | HRP20161295T1 (https=) |
| HU (1) | HUE029933T2 (https=) |
| LT (1) | LT2827858T (https=) |
| MX (1) | MX356948B (https=) |
| PL (1) | PL2827858T3 (https=) |
| PT (1) | PT2827858T (https=) |
| RS (1) | RS55250B1 (https=) |
| RU (1) | RU2638795C2 (https=) |
| SI (1) | SI2827858T1 (https=) |
| WO (1) | WO2013139687A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112353762A (zh) * | 2013-01-22 | 2021-02-12 | 霍夫曼-拉罗奇有限公司 | 具有改善的生物利用度的药物组合物 |
| EP3459933B1 (en) | 2014-04-15 | 2022-08-24 | F. Hoffmann-La Roche AG | Solid forms of a pharmaceutically active compound |
| TW201613576A (en) | 2014-06-26 | 2016-04-16 | Novartis Ag | Intermittent dosing of MDM2 inhibitor |
| EP3204776B1 (en) * | 2014-10-10 | 2019-09-04 | F.Hoffmann-La Roche Ag | Methods for personalizing patient cancer therapy with an mdm2 antagonist |
| AU2017246452C1 (en) | 2016-04-06 | 2021-06-03 | The Regents Of The University Of Michigan | MDM2 protein degraders |
| MX388093B (es) | 2016-11-15 | 2025-03-19 | Novartis Ag | Dosis y regimen para inhibidores de la interaccion hdm2-p53. |
| US20210122831A1 (en) | 2017-03-27 | 2021-04-29 | Noile-Immune Biotech, Inc. | Chimeric antigen receptor |
| CA3052543A1 (en) | 2017-03-31 | 2018-10-04 | Novartis Ag | Dose and regimen for an hdm2-p53 interaction inhibitor in hematological tumors |
| TWI791794B (zh) | 2018-03-20 | 2023-02-11 | 瑞士商諾華公司 | 藥物組合 |
| MX2021007391A (es) | 2018-12-20 | 2021-09-23 | Novartis Ag | Regimenes de baja dosis extendida para inhibidores de mdm2. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101595107A (zh) * | 2006-06-30 | 2009-12-02 | 先灵公司 | 能提高p53活性的有取代哌啶及其用途 |
| WO2008076415A1 (en) | 2006-12-14 | 2008-06-26 | Exelixis, Inc. | Methods of using mek inhibitors |
| US8354444B2 (en) * | 2008-09-18 | 2013-01-15 | Hoffmann-La Roche Inc. | Substituted pyrrolidine-2-carboxamides |
| US20120010235A1 (en) * | 2010-07-12 | 2012-01-12 | Xin-Jie Chu | N-substituted pyrrolidines |
| US9216170B2 (en) | 2012-03-19 | 2015-12-22 | Hoffmann-La Roche Inc. | Combination therapy for proliferative disorders |
-
2013
- 2013-02-05 US US13/759,647 patent/US20130245089A1/en not_active Abandoned
- 2013-03-15 EP EP13711004.5A patent/EP2827858B1/en active Active
- 2013-03-15 KR KR1020217003250A patent/KR102438597B1/ko active Active
- 2013-03-15 RU RU2014141365A patent/RU2638795C2/ru active
- 2013-03-15 WO PCT/EP2013/055324 patent/WO2013139687A1/en not_active Ceased
- 2013-03-15 CA CA2859940A patent/CA2859940C/en active Active
- 2013-03-15 CN CN201380015189.5A patent/CN104203232A/zh active Pending
- 2013-03-15 DK DK13711004.5T patent/DK2827858T3/en active
- 2013-03-15 RS RS20160860A patent/RS55250B1/sr unknown
- 2013-03-15 PT PT137110045T patent/PT2827858T/pt unknown
- 2013-03-15 MX MX2014010586A patent/MX356948B/es active IP Right Grant
- 2013-03-15 PL PL13711004T patent/PL2827858T3/pl unknown
- 2013-03-15 KR KR1020147026019A patent/KR20140133583A/ko not_active Ceased
- 2013-03-15 HR HRP20161295TT patent/HRP20161295T1/hr unknown
- 2013-03-15 JP JP2015500851A patent/JP6224690B2/ja active Active
- 2013-03-15 ES ES13711004.5T patent/ES2593066T3/es active Active
- 2013-03-15 LT LTEP13711004.5T patent/LT2827858T/lt unknown
- 2013-03-15 HK HK15105538.1A patent/HK1204934A1/xx unknown
- 2013-03-15 KR KR1020197008801A patent/KR20190035957A/ko not_active Ceased
- 2013-03-15 KR KR1020167019798A patent/KR20160089549A/ko not_active Ceased
- 2013-03-15 BR BR112014018135A patent/BR112014018135A8/pt not_active Application Discontinuation
- 2013-03-15 SI SI201330310A patent/SI2827858T1/sl unknown
- 2013-03-15 CN CN201910030832.0A patent/CN110013478A/zh active Pending
- 2013-03-15 HU HUE13711004A patent/HUE029933T2/en unknown
-
2015
- 2015-01-14 US US14/596,747 patent/US20150126575A1/en not_active Abandoned
-
2016
- 2016-10-05 CY CY20161100996T patent/CY1118070T1/el unknown
- 2016-10-06 JP JP2016197838A patent/JP2017061461A/ja active Pending
-
2019
- 2019-07-12 US US16/510,256 patent/US20190328708A1/en not_active Abandoned
-
2020
- 2020-11-18 US US16/951,153 patent/US11738003B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112014018135A8 (pt) | Produto farmacêutico e uso do produto farmacêutico | |
| UY34698A (es) | Combinaciones farmacéuticas que comprenden un análogo de tionucleótidos | |
| PH12016501151A1 (en) | Nrf2 regulators | |
| CY1120480T1 (el) | Ενωσεις πυραζολοπυριμιδινης | |
| CU20160020A7 (es) | Derivados de imidazoquinolinas sustituidas inhibidores de mek para el tratamiento del cáncer | |
| CU20140081A7 (es) | Nuevos derivados de pirrol, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| EA201400591A1 (ru) | Ингалятор | |
| DOP2015000241A (es) | Compuestos de biaril-amida como inhibidores de cinasa | |
| EA201401292A2 (ru) | Новые тиенопиримидиновые производные, способ их получения и фармацевтические композиции, содержащие их | |
| CU20140095A7 (es) | Nuevos derivados fosfatos, su procedimiento de preparación y las composiciones farmacéuticas que los contienen | |
| PE20150887A1 (es) | Compuestos de benceno sustituidos | |
| MX2020001258A (es) | Moduladores del factor del complemento b. | |
| IN2014DN06501A (https=) | ||
| MX2016003199A (es) | Compuestos de azapiridona y usos de los mismos. | |
| EA201492287A1 (ru) | Дейтерированные производные руксолитиниба | |
| GEP201706621B (en) | Benzamides | |
| UA116889C2 (uk) | Фармацевтична композиція, що містить суміш ізоформ apg101 (cd95-fc) | |
| EA201590954A1 (ru) | Дигидропиразольные модуляторы gpr40 | |
| MX2019006878A (es) | Uso de flecainida como un agente anti-conexina y metodo para potenciar los efectos de un farmaco psicotropico. | |
| PH12015501993B1 (en) | Pyrazole-amide compound and medicinal uses therefor | |
| EA201590949A1 (ru) | Дигидропиразольные модуляторы gpr40 | |
| PH12019501178A1 (en) | Thiopene derivatives as antiviral agents | |
| EA201301061A1 (ru) | Фармацевтическая композиция, содержащая инозит | |
| MY168212A (en) | A new therapeutical composition containing apomorphine as active ingredient | |
| MX2015012833A (es) | Composiciones antibioticas de ceftolozano. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |