BR112014017175A8 - proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros - Google Patents

proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros

Info

Publication number
BR112014017175A8
BR112014017175A8 BR112014017175A BR112014017175A BR112014017175A8 BR 112014017175 A8 BR112014017175 A8 BR 112014017175A8 BR 112014017175 A BR112014017175 A BR 112014017175A BR 112014017175 A BR112014017175 A BR 112014017175A BR 112014017175 A8 BR112014017175 A8 BR 112014017175A8
Authority
BR
Brazil
Prior art keywords
proximal
region
cosmetic
treatments
skin protection
Prior art date
Application number
BR112014017175A
Other languages
English (en)
Other versions
BR112014017175A2 (pt
Inventor
Allison John
Fourkas Michael
Williams Ronald
Original Assignee
Myoscience Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Myoscience Inc filed Critical Myoscience Inc
Priority claimed from PCT/US2013/021488 external-priority patent/WO2013106857A1/en
Publication of BR112014017175A2 publication Critical patent/BR112014017175A2/pt
Publication of BR112014017175A8 publication Critical patent/BR112014017175A8/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • A61L31/088Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/0046Surgical instruments, devices or methods, e.g. tourniquets with a releasable handle; with handle and operating part separable
    • A61B2017/00473Distal part, e.g. tip or head
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00743Type of operation; Specification of treatment sites
    • A61B2017/00747Dermatology
    • A61B2017/00761Removing layer of skin tissue, e.g. wrinkles, scars or cancerous tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00005Cooling or heating of the probe or tissue immediately surrounding the probe
    • A61B2018/00041Heating, e.g. defrosting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00089Thermal conductivity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00059Material properties
    • A61B2018/00089Thermal conductivity
    • A61B2018/00095Thermal conductivity high, i.e. heat conducting
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00107Coatings on the energy applicator
    • A61B2018/00148Coatings on the energy applicator with metal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00452Skin
    • A61B2018/00458Deeper parts of the skin, e.g. treatment of vascular disorders or port wine stains
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0293Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00Materials characterised by their function or physical properties
    • A61L2400/18Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/40Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking

Abstract

abstract of the disclosure a cryogenic needle probe having a proximal and distal region. a cooling supply tube provides pressurized cooling fluid within the needle. the proximal region is more conductive that the distal region. the proximal region is conductively coupled to a heat source. ************************** tradução do resumo resumo patente de invenção: "proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros". a presente invenção refere-se a uma sonda de agulha criogênica que tem uma região proximal e uma distal. um tubo de suprimento de resfriamento provê um fluido de resfriamento pressurizado dentro da agulha. a região proximal é mais condutiva que a região distal. a região proximal é acoplada de forma condutiva a uma fonte de calor. 21785964v1 1/1 21785964v1
BR112014017175A 2012-01-13 2013-01-14 proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros BR112014017175A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261586692P 2012-01-13 2012-01-13
PCT/US2013/021488 WO2013106857A1 (en) 2012-01-13 2013-01-14 Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments

Publications (2)

Publication Number Publication Date
BR112014017175A2 BR112014017175A2 (pt) 2017-06-13
BR112014017175A8 true BR112014017175A8 (pt) 2017-07-04

Family

ID=48780478

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112014017175A BR112014017175A8 (pt) 2012-01-13 2013-01-14 proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros

Country Status (5)

Country Link
US (2) US9241753B2 (pt)
EP (1) EP2802280B1 (pt)
CN (1) CN104159534B (pt)
BR (1) BR112014017175A8 (pt)
CA (1) CA2860893A1 (pt)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5763646B2 (ja) 2009-09-18 2015-08-12 ヴィヴェブ・インコーポレーテッド 膣再構築装置及び膣再構築方法
US9241753B2 (en) 2012-01-13 2016-01-26 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments
WO2013106859A1 (en) 2012-01-13 2013-07-18 Myoscience, Inc. Cryogenic needle with freeze zone regulation
US20140276359A1 (en) * 2013-03-15 2014-09-18 Plum Systems Co. Apparatus and method for tissue rejuvenation
US10016229B2 (en) 2013-03-15 2018-07-10 Myoscience, Inc. Methods and systems for treatment of occipital neuralgia
US9295512B2 (en) 2013-03-15 2016-03-29 Myoscience, Inc. Methods and devices for pain management
US9610112B2 (en) 2013-03-15 2017-04-04 Myoscience, Inc. Cryogenic enhancement of joint function, alleviation of joint stiffness and/or alleviation of pain associated with osteoarthritis
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
WO2015069792A1 (en) 2013-11-05 2015-05-14 Myoscience, Inc. Secure cryosurgical treatment system
US10660688B2 (en) * 2014-05-12 2020-05-26 Gary Kalser Cryotherapy device with cryoprotection and methods for performing cryotherapy with cryoprotection
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US11471401B2 (en) 2014-08-28 2022-10-18 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
BR112017003143B1 (pt) 2014-08-28 2023-12-05 The General Hospital Corporation Suspensões injetáveis, métodos para fabricação das mesmas e seus usos
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
US11324534B2 (en) 2014-11-14 2022-05-10 Cytrellis Biosystems, Inc. Devices and methods for ablation of the skin
US9554713B2 (en) * 2015-03-02 2017-01-31 Global Pediatric Surgical Technology and Education Project, Inc. Probe stimulator
BR112017019272A2 (pt) 2015-03-10 2018-05-02 Allergan Pharmaceuticals Holdings Ireland Unlimited Company injetor de múltiplas agulhas
MX2018010220A (es) 2016-02-26 2018-11-29 Massachusetts Gen Hospital Sistemas y metodos de produccion y suministro de suspension medica helada.
RU2725968C2 (ru) 2016-04-08 2020-07-07 Аллерган, Инк. Аспирационно-инъекционное устройство
JP2019531168A (ja) * 2016-08-30 2019-10-31 ザ ジェネラル ホスピタル コーポレイション 細胞組織治療のための凍結療法および凍結切除システムおよび方法
CN106344116B (zh) * 2016-10-13 2019-01-29 武汉大学 一种可视化智能陶瓷针刀
KR101905830B1 (ko) 2016-11-15 2018-10-08 울산과학기술원 국부 냉각 마취 장치, 국부 냉각 마취 장치의 제어 방법 및 국부 냉각 마취 장치의 냉각 온도 조절기
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
WO2018221848A1 (ko) 2017-05-30 2018-12-06 주식회사 리센스메디컬 의료용 냉각 장치
KR20180131359A (ko) 2017-05-30 2018-12-10 주식회사 리센스메디컬 의료용 냉각 장치
US11013547B2 (en) 2017-06-30 2021-05-25 R2 Technologies, Inc. Dermatological cryospray devices having linear array of nozzles and methods of use
KR102517065B1 (ko) 2017-12-29 2023-04-03 주식회사 리센스메디컬 냉각발생장치
USD999392S1 (en) * 2018-01-01 2023-09-19 Rooijakkers Huisman L S Vibrator
ES2941267T3 (es) 2018-04-27 2023-05-19 Recensmedical Inc Aparato de enfriamiento y método de enfriamiento
AU2019204574A1 (en) 2018-06-27 2020-01-23 Viveve, Inc. Methods for treating urinary stress incontinence
CN108904036B (zh) * 2018-07-17 2024-01-12 广州复大医疗有限公司 防皮肤冻伤装置、防皮肤冻伤袋及其使用方法
US11666479B2 (en) 2018-08-19 2023-06-06 Recensmedical, Inc. Device for cooling anesthesia by chilled fluidic cooling medium
USD921211S1 (en) 2019-06-21 2021-06-01 Recensmedical, Inc. Medical cooling device
USD921911S1 (en) 2019-06-21 2021-06-08 Recensmedical, Inc. Medical cooling device
CN115038396A (zh) 2019-10-29 2022-09-09 帕西拉冷冻技术股份有限公司 带有快速连接的针式探头的低温装置
USD914903S1 (en) * 2019-11-04 2021-03-30 Shenzhen Boyuan Intelligent Electronic Technology Co., Ltd Beauty instrument
WO2021108141A1 (en) 2019-11-27 2021-06-03 Pacira Cryotech, Inc. Display device and interfaces for cryogenic devices
JP2023504366A (ja) 2019-12-03 2023-02-03 パシラ クライオテック インコーポレイテッド 低温装置の圧力の安定化
CN111084658B (zh) * 2020-03-23 2020-07-24 上海导向医疗系统有限公司 冷冻粘连装置
US11278341B2 (en) 2020-07-14 2022-03-22 Recensmedical, Inc. Method of safely using controlled cooling systems and devices
USD977633S1 (en) 2020-08-07 2023-02-07 Recensmedical, Inc. Cradle for a medical cooling device
USD968626S1 (en) 2020-08-07 2022-11-01 Recensmedical, Inc. Medical cooling device
USD968627S1 (en) 2020-08-07 2022-11-01 Recensmedical, Inc. Medical cooling device
USD912263S1 (en) * 2020-08-22 2021-03-02 Guangdong Yunshangmei Technology Co., Ltd. Blackhead remover
USD949415S1 (en) * 2020-09-14 2022-04-19 Health Bloom, LLC Electrical stimulation device
USD950754S1 (en) 2020-10-30 2022-05-03 Health Bloom, LLC Electrical stimulation device
US11241330B1 (en) 2021-04-02 2022-02-08 Brixton Biosciences, Inc. Apparatus for creation of injectable slurry

Family Cites Families (211)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2319542A (en) 1940-06-24 1943-05-18 Franklin E Hall Therapeutic machine
US2672032A (en) 1951-10-19 1954-03-16 Towse Robert Albert Edward Carcass freezing device
US3289424A (en) 1963-07-01 1966-12-06 Union Carbide Corp Cryosurgical fluid control system
US3266492A (en) 1963-09-06 1966-08-16 Samuel B Steinberg Cryosurgery probe device
US3351063A (en) 1964-12-08 1967-11-07 Stephen F Malaker Cryosurgical probe
US3439680A (en) 1965-04-12 1969-04-22 Univ Northwestern Surgical instrument for cataract removal
US3343544A (en) 1965-12-21 1967-09-26 Alcon Lab Inc Cryogenic surgical instrument
GB1103079A (en) 1966-02-17 1968-02-14 Internat Res And Dev Company L Improvements in and relating to surgical probes
US3532094A (en) 1967-07-20 1970-10-06 Norman O Stahl Cryogenic-instrument with detachable probe
US3507283A (en) 1967-10-11 1970-04-21 Univ Northwestern Cryosurgical instrument
US3702114A (en) 1970-08-26 1972-11-07 Frigitronics Of Conn Inc Liquid refrigerant spray device
US3664344A (en) 1970-09-15 1972-05-23 Brymill Corp Tyned cryosurgical probe
US3795245A (en) 1971-04-29 1974-03-05 Al Co Du Splash-proof leak-proof syringe-type cryosurgical instrument
GB1360353A (en) 1972-01-19 1974-07-17 Atomic Energy Authority Uk Method of making thermocouples
GB1402632A (en) 1972-02-02 1975-08-13 Wilkinson Sword Ltd Medical equipment
US3814095A (en) 1972-03-24 1974-06-04 H Lubens Occlusively applied anesthetic patch
US3886945A (en) 1972-06-14 1975-06-03 Frigitronics Of Conn Inc Cryosurgical apparatus
US3830239A (en) 1972-09-12 1974-08-20 Frigitronics Of Conn Inc Cryosurgical device
US4022215A (en) * 1973-12-10 1977-05-10 Benson Jerrel W Cryosurgical system
US3951152A (en) 1974-06-03 1976-04-20 Dynatech Corporation Cryosurgical probe
US3889681A (en) 1974-10-30 1975-06-17 Jack Douglas Waller Cryosurgical spraying apparatus
US3993075A (en) 1975-12-24 1976-11-23 Dynatech Corporation Disposable, defrostable cryosurgical probe
GB1534162A (en) 1976-07-21 1978-11-29 Lloyd J Cyosurgical probe
US4140109A (en) 1977-10-17 1979-02-20 Savic Michael I Impedance-based method and apparatus for monitoring cryodestruction in controlled cryosurgery
US4236518A (en) 1978-04-14 1980-12-02 Gyne-Tech Instrument Corporation Cryogenic device selectively operable in a continuous freezing mode, a continuous thawing mode or a combination thereof
US4306568A (en) 1979-12-04 1981-12-22 Torre Douglas P Method and apparatus for congelation cryometry in cryosurgery
US4376376A (en) 1980-05-12 1983-03-15 Virginia M. Gregory Cryogenic device operable in single or dual phase with a range of nozzle sizes and method of using the same
DE3022216A1 (de) 1980-06-13 1982-01-28 Heinz 3012 Langenhagen Hennecke Tieftemperaturuebertragungseinrichtung fuer medizinische zwecke
US4404862A (en) 1981-11-02 1983-09-20 Dynatech Precision Sampling Corporation Microdispensing springs with a needle in a tubular extension
US4524771A (en) 1982-10-28 1985-06-25 Ethicon Inc. Multiple curved surgical needle
JPS6013111A (ja) 1983-06-30 1985-01-23 Oyo Suiken Kk 2重管式変圧定量注水方法
JPS6013111U (ja) 1983-07-04 1985-01-29 株式会社 東理社 外科用消息子
GB2190842B (en) 1986-05-05 1990-03-07 Oreal Apparatus for the cryogenic treatment of the skin
US4802475A (en) 1987-06-22 1989-02-07 Weshahy Ahmed H A G Methods and apparatus of applying intra-lesional cryotherapy
JPH0538347Y2 (pt) 1987-10-28 1993-09-28
GB2230191B (en) 1989-04-15 1992-04-22 Robert Graham Urie Lesion location device
US4946460A (en) 1989-04-26 1990-08-07 Cryo Instruments, Inc. Apparatus for cryosurgery
US5200170A (en) 1989-07-18 1993-04-06 Mcdow Ronald A Medical process--use of dichlorodifluoromethane (CCl2 F2) and chlorodifluoromethane (CHClF2) as cryogens for treating skin lesions
ZA917281B (en) 1990-09-26 1992-08-26 Cryomedical Sciences Inc Cryosurgical instrument and system and method of cryosurgery
JP3142008B2 (ja) 1991-06-03 2001-03-07 株式会社前川製作所 生体凍結用治療針
JPH0538347A (ja) 1991-08-06 1993-02-19 Mayekawa Mfg Co Ltd 生体組織凍結装置
US7549424B2 (en) 1991-10-18 2009-06-23 Pro Surg, Inc. Method and apparatus for tissue treatment with laser and electromagnetic radiation
EP0680283B1 (en) 1992-04-24 1998-05-13 Surgical Laser Technologies Thermally-resistant medical probe
US5294325A (en) 1992-07-09 1994-03-15 World Precision Instruments, Inc. Miniaturized fluid conveying device and methods of use thereof
DE4322955B4 (de) 1992-07-20 2007-12-20 Aesculap Ag & Co. Kg Invasives chirurgisches Instrument
US5571147A (en) 1993-11-02 1996-11-05 Sluijter; Menno E. Thermal denervation of an intervertebral disc for relief of back pain
US5647868A (en) 1994-02-02 1997-07-15 Chinn; Douglas Owen Cryosurgical integrated control and monitoring system and method
US5536249A (en) 1994-03-09 1996-07-16 Visionary Medical Products, Inc. Pen-type injector with a microprocessor and blood characteristic monitor
JP3263275B2 (ja) 1994-04-05 2002-03-04 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 生体組織のレーザー処理のための装置並びに火焔状斑点母斑のレーザー処理装置
US6277116B1 (en) 1994-05-06 2001-08-21 Vidaderm Systems and methods for shrinking collagen in the dermis
GB2289510A (en) 1994-05-10 1995-11-22 Spembly Medical Ltd Connector
GB2289414B (en) 1994-05-10 1998-05-13 Spembly Medical Ltd Cryosurgical instrument
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
JPH08206147A (ja) 1995-02-06 1996-08-13 Akio Usui 発熱体及びこれを用いる貼付剤
JP3283716B2 (ja) 1995-04-07 2002-05-20 シャープ株式会社 ヒータ制御装置
US5755753A (en) 1995-05-05 1998-05-26 Thermage, Inc. Method for controlled contraction of collagen tissue
US7620290B2 (en) 1995-08-31 2009-11-17 Biolase Technology, Inc. Modified-output fiber optic tips
FR2739557B1 (fr) 1995-10-09 1997-11-14 Cird Galderma Utilisation d'un ligand agoniste specifique rar-gamma
US6350276B1 (en) 1996-01-05 2002-02-26 Thermage, Inc. Tissue remodeling apparatus containing cooling fluid
US20040000316A1 (en) 1996-01-05 2004-01-01 Knowlton Edward W. Methods for creating tissue effect utilizing electromagnetic energy and a reverse thermal gradient
US7189230B2 (en) 1996-01-05 2007-03-13 Thermage, Inc. Method for treating skin and underlying tissue
US6682501B1 (en) 1996-02-23 2004-01-27 Gyrus Ent, L.L.C. Submucosal tonsillectomy apparatus and method
US6039730A (en) 1996-06-24 2000-03-21 Allegheny-Singer Research Institute Method and apparatus for cryosurgery
JPH1014656A (ja) 1996-07-01 1998-01-20 Shigemi Kobayashi 顔の皺取り具
US5899897A (en) 1996-09-26 1999-05-04 Allegheny-Singer Research Institute Method and apparatus for heating during cryosurgery
US5910104A (en) 1996-12-26 1999-06-08 Cryogen, Inc. Cryosurgical probe with disposable sheath
AU6865298A (en) 1997-03-17 1998-10-12 Boris Rubinsky The use of cryoprotective agent compounds during cryosurgery
US6032675A (en) 1997-03-17 2000-03-07 Rubinsky; Boris Freezing method for controlled removal of fatty tissue by liposuction
US7347840B2 (en) 2000-03-02 2008-03-25 Pyng Medical Corp. Patch for locating a target zone for penetration
US5976505A (en) 1997-07-02 1999-11-02 Hcs Trust Method for cryogenically treating psoriasis with liquid nitrogen or liquid nitrous oxide
US6371943B1 (en) 1997-09-08 2002-04-16 Epimed International, Inc. Spring tip needle combination
US5971979A (en) 1997-12-02 1999-10-26 Odyssey Technologies, Inc. Method for cryogenic inhibition of hyperplasia
JP3422678B2 (ja) 1998-01-20 2003-06-30 エヌオーケー株式会社 差圧弁及び液体遮断弁装置
US6051019A (en) * 1998-01-23 2000-04-18 Del Mar Medical Technologies, Inc. Selective organ hypothermia method and apparatus
US5916212A (en) 1998-01-23 1999-06-29 Cryomedical Sciences, Inc. Hand held cyrosurgical probe system
FR2775589B1 (fr) 1998-03-06 2000-04-28 Cryonic Medical Appareil autonome et portable de cryogenie utilisant l'anhydride carbonique en phase liquide/solide
US6905494B2 (en) 1998-03-31 2005-06-14 Innercool Therapies, Inc. Method and device for performing cooling- or cryo-therapies for, e.g., angioplasty with reduced restenosis or pulmonary vein cell necrosis to inhibit atrial fibrillation employing tissue protection
US6142991A (en) 1998-03-31 2000-11-07 Galil Medical, Ltd. High resolution cryosurgical method and apparatus
US6139545A (en) 1998-09-09 2000-10-31 Vidaderm Systems and methods for ablating discrete motor nerve regions
US6306119B1 (en) 1999-01-20 2001-10-23 Pearl Technology Holdings, Llc Skin resurfacing and treatment using biocompatible materials
US6196839B1 (en) 1999-01-29 2001-03-06 Robert Gregg Ross Continuous use orthodontic cooling appliance
US6468297B1 (en) 1999-02-24 2002-10-22 Cryovascular Systems, Inc. Cryogenically enhanced intravascular interventions
US6432102B2 (en) 1999-03-15 2002-08-13 Cryovascular Systems, Inc. Cryosurgical fluid supply
US6964668B2 (en) 1999-03-04 2005-11-15 Abbott Laboratories Articulating suturing device and method
US7001400B1 (en) 1999-03-04 2006-02-21 Abbott Laboratories Articulating suturing device and method
US7235087B2 (en) 1999-03-04 2007-06-26 Abbott Park Articulating suturing device and method
US20040092964A1 (en) 1999-03-04 2004-05-13 Modesitt D. Bruce Articulating suturing device and method
US6562030B1 (en) 1999-04-06 2003-05-13 Cryocath Technologies Inc. Heater control of cryocatheter tip temperature
US6256533B1 (en) 1999-06-09 2001-07-03 The Procter & Gamble Company Apparatus and method for using an intracutaneous microneedle array
EP1151729A1 (en) 1999-08-05 2001-11-07 Broncus Technologies, Inc. Methods and devices for creating collateral channels in the lungs
US6277099B1 (en) 1999-08-06 2001-08-21 Becton, Dickinson And Company Medication delivery pen
US20020193740A1 (en) 1999-10-14 2002-12-19 Alchas Paul G. Method of intradermally injecting substances
GB2355728A (en) 1999-10-27 2001-05-02 Anson Medical Ltd Tubular medical implants and methods of manufacture
JP2001178737A (ja) 1999-12-07 2001-07-03 Dieter Steinfatt 凍結装置
US6669688B2 (en) 2000-01-25 2003-12-30 The Regents Of The University Of California Method and apparatus for measuring the heat transfer coefficient during cryogen spray cooling of tissue
US6363730B1 (en) 2000-03-15 2002-04-02 The Conair Group, Inc. Method and apparatus for cryogenic cooling
US6546935B2 (en) 2000-04-27 2003-04-15 Atricure, Inc. Method for transmural ablation
US6494844B1 (en) 2000-06-21 2002-12-17 Sanarus Medical, Inc. Device for biopsy and treatment of breast tumors
US6503246B1 (en) 2000-07-05 2003-01-07 Mor Research Applications Ltd. Cryoprobe and method of treating scars
EP1463437B1 (en) 2000-07-31 2012-01-04 Galil Medical Ltd. Facilitation system for cryosurgery
US6902554B2 (en) 2000-07-31 2005-06-07 Bionix Development Corporation Method for controlling the pain from injections or minor surgical procedures and apparatus for use therewith
US6840935B2 (en) 2000-08-09 2005-01-11 Bekl Corporation Gynecological ablation procedure and system using an ablation needle
US6955174B2 (en) 2000-08-18 2005-10-18 Uryovascular Systems, Inc. Cryotherapy method for detecting and treating vulnerable plaque
WO2002019573A2 (en) 2000-08-31 2002-03-07 Aerocomm, Inc. System and method for transmitting information modulated radio frequency signals using infrared transmission
US6551309B1 (en) 2000-09-14 2003-04-22 Cryoflex, Inc. Dual action cryoprobe and methods of using the same
CA2425793A1 (en) 2000-10-16 2002-04-25 Kevin H. Van Bladel Device for biopsy of tumors
US20020068929A1 (en) 2000-10-24 2002-06-06 Roni Zvuloni Apparatus and method for compressing a gas, and cryosurgery system and method utilizing same
US6706037B2 (en) 2000-10-24 2004-03-16 Galil Medical Ltd. Multiple cryoprobe apparatus and method
US6723092B2 (en) 2000-12-15 2004-04-20 Tony R. Brown Atrial fibrillation RF treatment device and method
US20040162551A1 (en) 2000-12-15 2004-08-19 Brown Tony R. Method and device for creating transmural lesions
US7029480B2 (en) 2001-01-24 2006-04-18 Abott Laboratories Device and method for suturing of internal puncture sites
US6648880B2 (en) 2001-02-16 2003-11-18 Cryocath Technologies Inc. Method of using cryotreatment to treat brain tissue
US7422586B2 (en) 2001-02-28 2008-09-09 Angiodynamics, Inc. Tissue surface treatment apparatus and method
MXPA03009367A (es) 2001-04-13 2004-01-29 Becton Dickinson Co DISPOSITIVO PARA SUMINISTRO INTRADeRMICO QUE PUEDE SER PRELLENADO.
US6761715B2 (en) 2001-04-26 2004-07-13 Ronald J. Carroll Method and device for neurocryo analgesia and anesthesia
EP2258424B1 (en) 2001-05-16 2013-01-30 Eli Lilly and Company Medication injector apparatus
GB0111986D0 (en) 2001-05-16 2001-07-04 Optomed As Cryosurgical apparatus and methods
US20080051776A1 (en) 2001-05-21 2008-02-28 Galil Medical Ltd. Thin uninsulated cryoprobe and insulating probe introducer
US6786900B2 (en) 2001-08-13 2004-09-07 Cryovascular Systems, Inc. Cryotherapy methods for treating vessel dissections and side branch occlusion
WO2003026476A2 (en) 2001-09-27 2003-04-03 Galil Medical Ltd. Apparatus and method for cryosurgical treatment of tumors of the breast
US7479139B2 (en) 2002-01-04 2009-01-20 Galil Medical Ltd. Apparatus and method for protecting tissues during cryoablation
US7250046B1 (en) 2002-02-27 2007-07-31 Fallat Lawrence M Treatment of lower extremity pain
ATE386491T1 (de) 2002-03-15 2008-03-15 Gen Hospital Corp Vorrichtungen für die selektive zerstörung von fettgewebe durch kontrollierte kühlung
TW557219B (en) 2002-06-28 2003-10-11 Jiun-Guang Luo Quick-freezing medical device
SE523503C2 (sv) 2002-07-23 2004-04-27 Jettec Ab Kapillärrör
US7393350B2 (en) * 2002-08-06 2008-07-01 Erbe Elektromedizin Gmbh Cryo-surgical apparatus and methods
US6858025B2 (en) * 2002-08-06 2005-02-22 Medically Advanced Designs, Llc Cryo-surgical apparatus and method of use
US7338504B2 (en) 2002-10-03 2008-03-04 Gibbens Group, L.L.C. Cycling suturing and knot-tying device
US6789545B2 (en) 2002-10-04 2004-09-14 Sanarus Medical, Inc. Method and system for cryoablating fibroadenomas
MXPA05003705A (es) 2002-10-09 2005-08-16 Central Iowa Health System Vacunacion antitumoral usando celulas de tumor alogeneico que expresan alfa (1,3)-galactosil transferasa.
DE10250629A1 (de) 2002-10-30 2004-05-19 Tecpharma Licensing Ag Verfahren und Vorrichtung zur Anzeige und Dosierung bei der Verabreichung eines Produkts
US6896666B2 (en) 2002-11-08 2005-05-24 Kochamba Family Trust Cutaneous injection delivery under suction
WO2004045434A2 (fr) 2002-11-18 2004-06-03 N.V. H & O Equipments Instrument destine aux traitements cryogeniques dans le secteur medical, paramedical et cosmetique
US20040122482A1 (en) 2002-12-20 2004-06-24 James Tung Nerve proximity method and device
US7273479B2 (en) 2003-01-15 2007-09-25 Cryodynamics, Llc Methods and systems for cryogenic cooling
WO2004064914A2 (en) 2003-01-15 2004-08-05 Cryodynamics, Llc. Cryotherapy probe and system
US7083612B2 (en) 2003-01-15 2006-08-01 Cryodynamics, Llc Cryotherapy system
US7410484B2 (en) 2003-01-15 2008-08-12 Cryodynamics, Llc Cryotherapy probe
US6936048B2 (en) 2003-01-16 2005-08-30 Charlotte-Mecklenburg Hospital Authority Echogenic needle for transvaginal ultrasound directed reduction of uterine fibroids and an associated method
CA2519120C (en) 2003-03-13 2017-11-07 Cheryl M. Burgess Methods of administering a material into a patient for dermal enhancement
US20040204705A1 (en) 2003-04-10 2004-10-14 Scimed Life Systems, Inc. Cryotreatment devices and methods of forming conduction blocks
US20060224149A1 (en) 2003-04-21 2006-10-05 Galil Medical Ltd. Apparatus and method positioning a therapeutic probe with respect to a therapeutic target
US7160291B2 (en) 2003-06-25 2007-01-09 Endocare, Inc. Detachable cryosurgical probe
US7207985B2 (en) 2003-06-25 2007-04-24 Endocare, Inc. Detachable cryosurgical probe
US6960208B2 (en) 2003-06-30 2005-11-01 Boston Scientific Scimed, Inc. Apparatus and methods for delivering energy to a target site within bone
US20050004563A1 (en) 2003-07-01 2005-01-06 Racz N. Sandor Apparatus and methods for sensing and cooling during application of thermal energy for treating degenerative spinal discs
CN1579337A (zh) * 2003-07-30 2005-02-16 亚诺超导科技股份有限公司 急冻医疗方法与装置
US20050043723A1 (en) 2003-08-19 2005-02-24 Schering-Plough Healthcare Products, Inc. Cryosurgery device
JP2005080988A (ja) 2003-09-10 2005-03-31 Ruo Mei Ryan 冷凍治療装置及び熱伝導針手段
US20050203593A1 (en) 2003-10-24 2005-09-15 Shanks Steven C. Method for dermatology therapies in combination with low level laser treatments
US7381208B2 (en) 2003-12-22 2008-06-03 Ams Research Corporation Cryosurgical devices for endometrial ablation
US7402140B2 (en) 2004-02-12 2008-07-22 Sanarus Medical, Inc. Rotational core biopsy device with liquid cryogen adhesion probe
US7238184B2 (en) 2004-03-15 2007-07-03 Boston Scientific Scimed, Inc. Ablation probe with peltier effect thermal control
US7322973B2 (en) 2004-03-31 2008-01-29 Cryocath Technologies Inc. Method and apparatus for preventing atrial fibrillation
ES2611284T3 (es) 2004-04-01 2017-05-08 The General Hospital Corporation Aparato para tratamiento cutáneo y remodelación de tejido
US8177779B2 (en) 2004-06-02 2012-05-15 Boston Scientific Scimed, Inc. Controllable pressure cryogenic balloon treatment system and method
US20050283148A1 (en) 2004-06-17 2005-12-22 Janssen William M Ablation apparatus and system to limit nerve conduction
AU2005267378A1 (en) 2004-06-24 2006-02-02 Suture Robotics, Inc. Semi-robotic suturing device
DE602005010442D1 (de) 2004-08-16 2008-11-27 Zimmer Spine Inc Spiralförmige nähvorrichtung
US20060069385A1 (en) 2004-09-28 2006-03-30 Scimed Life Systems, Inc. Methods and apparatus for tissue cryotherapy
US20060190035A1 (en) 2004-10-08 2006-08-24 Sherwood Services Ag Latching mechanism for forceps
US7578819B2 (en) 2005-05-16 2009-08-25 Baxano, Inc. Spinal access and neural localization
AU2005295589B2 (en) 2004-10-15 2009-12-03 Baxano, Inc. Devices and methods for tissue removal
US20060089688A1 (en) 2004-10-25 2006-04-27 Dorin Panescu Method and apparatus to reduce wrinkles through application of radio frequency energy to nerves
JP4324673B2 (ja) 2004-11-05 2009-09-02 国立大学法人東北大学 ペルチェモジュールによる凍結治療装置
US7297136B2 (en) 2004-12-06 2007-11-20 Wyrick Ronald E Medicine injection devices and methods
US7604631B2 (en) 2004-12-15 2009-10-20 Boston Scientific Scimed, Inc. Efficient controlled cryogenic fluid delivery into a balloon catheter and other treatment devices
US8906039B2 (en) 2005-03-21 2014-12-09 Design Standards Corporation Suturing device
US20060223052A1 (en) 2005-03-30 2006-10-05 Kimberly-Clark Worldwide, Inc. Technique for detecting microorganisms
US7850683B2 (en) 2005-05-20 2010-12-14 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
US7713266B2 (en) 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
ES2338342T3 (es) 2005-05-27 2010-05-06 Instituto Tecnologico De Canarias, S.A. (Itc) Porta-agujas quirurgico para el suturado de puntos.
US20070055173A1 (en) 2005-08-23 2007-03-08 Sanarus Medical, Inc. Rotational core biopsy device with liquid cryogen adhesion probe
US8758375B2 (en) 2005-09-28 2014-06-24 Olympus Medical Systems Corp Method for suturing perforation
US7572268B2 (en) 2005-10-13 2009-08-11 Bacoustics, Llc Apparatus and methods for the selective removal of tissue using combinations of ultrasonic energy and cryogenic energy
US20080051775A1 (en) 2005-11-23 2008-02-28 Evans David K Multi-modal analgesia delivery system ("MADS")
JP4614451B2 (ja) 2005-12-26 2011-01-19 日本シャーウッド株式会社 医療用縫合具
US20070156125A1 (en) 2005-12-30 2007-07-05 Russell Delonzor Encodable cryogenic device
US7799018B2 (en) 2006-01-06 2010-09-21 Olga Goulko Cryogenic applicator for rejuvenating human skin and related method
JP5355094B2 (ja) 2006-01-27 2013-11-27 スターテック インコーポレイテッド 組織閉鎖装置および方法
US7854754B2 (en) 2006-02-22 2010-12-21 Zeltiq Aesthetics, Inc. Cooling device for removing heat from subcutaneous lipid-rich cells
EP2010084A2 (en) 2006-04-24 2009-01-07 Thomas Jefferson University Cryoneedle and cryotherapy system
KR101039758B1 (ko) 2006-04-28 2011-06-09 젤티크 애스세틱스, 인코포레이티드. 피하 지질 과다 세포의 개선된 냉각을 위한 치료 장치와함께 사용하기 위한 동결 방지제
WO2007129121A1 (en) 2006-05-08 2007-11-15 Tayside Health Board Device and method for improved surgical suturing
WO2007135629A1 (en) 2006-05-16 2007-11-29 Orhan Seyfi Aksakal A needle pusher
US20070270925A1 (en) 2006-05-17 2007-11-22 Juniper Medical, Inc. Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature
EP1862125B1 (en) 2006-05-31 2011-08-03 Covidien AG Medical suturing tool with gripping device
US8425502B2 (en) 2006-07-28 2013-04-23 Centre Hospitalier Universitaire de Québec Probe, sleeve, system, method and kit for performing percutaneous thermotherapy
US7803154B2 (en) 2006-08-03 2010-09-28 Arbel Medical Ltd. Cryogenic probe for treating enlarged volume of tissue
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US20080077201A1 (en) 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
WO2008055243A2 (en) 2006-10-31 2008-05-08 Zeltiq Aesthetics, Inc. Method and apparatus for cooling subcutaneous lipid-rich cells or tissue
US9254162B2 (en) 2006-12-21 2016-02-09 Myoscience, Inc. Dermal and transdermal cryogenic microprobe systems
US8409185B2 (en) 2007-02-16 2013-04-02 Myoscience, Inc. Replaceable and/or easily removable needle systems for dermal and transdermal cryogenic remodeling
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US20090018624A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Limiting use of disposable system patient protection devices
US20090018625A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Managing system temperature to remove heat from lipid-rich regions
US20090018626A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. User interfaces for a system that removes heat from lipid-rich regions
US20090018627A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Secure systems for removing heat from lipid-rich regions
EP2182898B1 (en) 2007-08-21 2018-10-03 Zeltiq Aesthetics, Inc. Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
US8298216B2 (en) 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
WO2009146053A1 (en) 2008-04-01 2009-12-03 The General Hospital Corporation Method and apparatus for cooling biological tissue
WO2009153755A2 (en) * 2008-06-18 2009-12-23 Arbel Medical Ltd. Cryosurgical instrument insulating system
EP2373239B1 (en) 2008-12-22 2013-08-14 Myoscience, Inc. Integrated cryosurgical system with refrigerant and electrical power source
EP2373240B1 (en) 2008-12-22 2015-04-29 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments
US20120089211A1 (en) 2010-04-08 2012-04-12 Myoscience, Inc. Methods and apparatus for cryogenically treating multiple tissue sites with a single puncture
US9039688B2 (en) 2010-12-13 2015-05-26 Myoscience, Inc. Method for reducing hyperdynamic facial wrinkles
US9241753B2 (en) 2012-01-13 2016-01-26 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments
WO2013106857A1 (en) 2012-01-13 2013-07-18 Myoscience, Inc. Skin protection for subdermal cryogenic remodeling for cosmetic and other treatments

Also Published As

Publication number Publication date
US20160095643A1 (en) 2016-04-07
CA2860893A1 (en) 2013-07-18
EP2802280B1 (en) 2016-11-30
CN104159534A (zh) 2014-11-19
EP2802280A1 (en) 2014-11-19
EP2802280A4 (en) 2015-08-19
US10188444B2 (en) 2019-01-29
CN104159534B (zh) 2017-02-22
BR112014017175A2 (pt) 2017-06-13
US20130184695A1 (en) 2013-07-18
US9241753B2 (en) 2016-01-26

Similar Documents

Publication Publication Date Title
BR112014017175A8 (pt) proteção de pele para remodelagem criogênica subdérmica para tratamentos cosméticos e outros
MX2016001666A (es) Dispositivo de inyeccion para procedimientos minimamente invasivos y usos del mismo.
BR112018012266A2 (pt) sonda eletrocirúrgica para entrega de energia de micro-ondas
BR112014032663A2 (pt) dispositivo para fixação óssea com ângulo variável
BR112014025826A2 (pt) método e aparelho para transecção com fio de um ligamento
BR112014016938A8 (pt) método, kit cirúrgico e dispositivo para tratar glaucoma
BR112014031708A2 (pt) porta agulha para uso em um dispositivo médico, e aparelho de cateterismo
BR112013026029A2 (pt) métodos e dispositivos para o aquecimento de fluido em terapia de ablação aprimorada com fluido
BR112015027762A2 (pt) Aparelho e métodos para injeção ocular
BR112015019663A2 (pt) sistema gerador de aerossol com aquecimento diferencial
BR112012022132A2 (pt) sistema de terapia a vapor
BR112013024653A2 (pt) cânula ajustável
BR112014008173A2 (pt) fixação de ativador para cateteres de controle de sangue
BR112015021441A2 (pt) sistemas e métodos eletrocirúrgicos
BR112016002465A2 (pt) terapia da combinação para o tratamento de câncer
BR112015012197A2 (pt) terapia de combinação
BR112016013299A2 (pt) Composto
BR112016004118A2 (pt) uso de inibidores da acetil-coa carboxilase para tratamento de acne vulgar
BR112015026297A2 (pt) terapia combinada composta por um inibidor tor quinase e um composto de 5-quinazolinona substituído para o tratamento de câncer
BR112016001446A8 (pt) composições terapêuticas, produto de combinação, uso in vitro de flecainida e flecainida
BR112013004843A2 (pt) "tubo-guia de ablação"
BR112015029823A2 (pt) inspeção de um gerador de vapor
BR112017011532A2 (pt) dispositivo para tratamento de pele por radiofrequência da pele de um usuário
BR112015004465A2 (pt) sistemas, dispositivos e métodos para fornecer terapia com orientação de imagem
BR112016006503A2 (pt) máscara respiratória com uma extensão de suporte nasal

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired
B350 Update of information on the portal [chapter 15.35 patent gazette]