BR112014010091B1 - Ácido nucleico, vetor viral, preparação farmacêutica, uso destes, método para produção de uma proteína rdcvf, e método in vitro ou ex vivo de secreção de uma proteína rdcvf a partir de uma célula - Google Patents

Ácido nucleico, vetor viral, preparação farmacêutica, uso destes, método para produção de uma proteína rdcvf, e método in vitro ou ex vivo de secreção de uma proteína rdcvf a partir de uma célula Download PDF

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BR112014010091B1
BR112014010091B1 BR112014010091-8A BR112014010091A BR112014010091B1 BR 112014010091 B1 BR112014010091 B1 BR 112014010091B1 BR 112014010091 A BR112014010091 A BR 112014010091A BR 112014010091 B1 BR112014010091 B1 BR 112014010091B1
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cell
rdcvf
protein
nucleic acid
cells
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BR112014010091-8A
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Portuguese (pt)
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BR112014010091A2 (pt
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Tianci Luo
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Wellstat Ophthalmics Corporation
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BR112014010091-8A 2011-10-27 2012-10-26 Ácido nucleico, vetor viral, preparação farmacêutica, uso destes, método para produção de uma proteína rdcvf, e método in vitro ou ex vivo de secreção de uma proteína rdcvf a partir de uma célula BR112014010091B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161552155P 2011-10-27 2011-10-27
US61/552,155 2011-10-27
PCT/US2012/062106 WO2013063383A2 (en) 2011-10-27 2012-10-26 Vectors encoding rod-derived cone viability factor

Publications (2)

Publication Number Publication Date
BR112014010091A2 BR112014010091A2 (pt) 2020-10-27
BR112014010091B1 true BR112014010091B1 (pt) 2022-11-08

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BR112014010091-8A BR112014010091B1 (pt) 2011-10-27 2012-10-26 Ácido nucleico, vetor viral, preparação farmacêutica, uso destes, método para produção de uma proteína rdcvf, e método in vitro ou ex vivo de secreção de uma proteína rdcvf a partir de uma célula

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US (2) US9265813B2 (https=)
EP (1) EP2797613B1 (https=)
JP (1) JP6293664B2 (https=)
KR (1) KR102000141B1 (https=)
CN (2) CN110777124A (https=)
AU (1) AU2012321102C1 (https=)
BR (1) BR112014010091B1 (https=)
CA (1) CA2853379C (https=)
DK (1) DK2797613T3 (https=)
ES (1) ES2774779T3 (https=)
MX (1) MX354516B (https=)
PL (1) PL2797613T3 (https=)
RU (1) RU2664673C2 (https=)
WO (1) WO2013063383A2 (https=)

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US10004780B2 (en) 2012-10-17 2018-06-26 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the treatment of age-related macular degeneration (AMD)
CN114395559A (zh) 2014-04-25 2022-04-26 吉尼松公司 高胆红素血症的治疗
JP6684343B2 (ja) * 2015-05-21 2020-04-22 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル ニューロン生存因子の相乗組み合わせ及びその使用
GB201516066D0 (en) 2015-09-10 2015-10-28 Young & Co Llp D Treatment of retinitis pigmentosa
JP7061067B2 (ja) 2015-12-14 2022-04-27 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア クリグラー・ナジャー症候群の処置のための組成物
US10857240B2 (en) 2016-01-05 2020-12-08 The Trustees Of The University Of Pennsylvania Methods and compositions for treatment of ocular disorders and blinding diseases
CN106148528B (zh) * 2016-07-11 2019-10-01 赵晨 一种遗传性Usher综合征的致病突变及其检测试剂
KR20230156440A (ko) * 2016-10-11 2023-11-14 웰스테이트 옵탈믹스 코퍼레이션 짧은 형태의 간상체 유래 원추체 생존능 인자와 친수성 펩타이드 사이의 융합 단백질
US12043848B2 (en) * 2017-10-16 2024-07-23 Vigeneron Gmbh AAV vectors
SG11202006796RA (en) * 2017-12-22 2020-08-28 Sparingvision Constructs comprising neuronal viability factors and uses thereof
JP7213891B2 (ja) * 2018-01-30 2023-01-27 ユニベルシテイト ゲント 白内障を処置するのに使用するための組成物
CN108504685A (zh) * 2018-03-27 2018-09-07 宜明细胞生物科技有限公司 一种利用CRISPR/Cas9系统同源重组修复IL-2RG缺陷基因的方法
CA3110745A1 (en) * 2018-09-07 2020-03-12 University Of Southern California Cryopreservation of cell-seeded substrates and related methods
BR112021009370A2 (pt) * 2018-11-14 2021-08-17 Regenxbio Inc. método de tratamento da doença de batten cln2, composição farmacêutica e kit
AU2019407921A1 (en) * 2018-12-19 2021-06-10 Versameb Ag RNA encoding a protein
WO2021050789A1 (en) 2019-09-10 2021-03-18 Obsidian Therapeutics, Inc. Ca2-il15 fusion proteins for tunable regulation
CN113260704B (zh) * 2019-12-09 2022-06-28 北京中因科技有限公司 CYP4V2和RdCVF在制备药物中的用途
CN111733174B (zh) * 2020-08-07 2021-02-09 北京大学第三医院（北京大学第三临床医学院） 一种分离的核酸分子及其用途
WO2022045935A1 (en) * 2020-08-28 2022-03-03 Joint Stock Company "Biocad" Aav5-based vaccine against sars-cov-2
KR20260008735A (ko) 2023-03-30 2026-01-16 파마 싱크, 엘엘씨 간상체-유래 원뿔세포 생존인자 및 인간 IgK 신호 서열을 인코딩하는 벡터
US20260091133A1 (en) * 2024-09-27 2026-04-02 Pharma Cinq, Llc Rod-derived cone viability factor fusion protein

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