BR112014007647A2 - “variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hp - Google Patents
“variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hpInfo
- Publication number
- BR112014007647A2 BR112014007647A2 BR112014007647A BR112014007647A BR112014007647A2 BR 112014007647 A2 BR112014007647 A2 BR 112014007647A2 BR 112014007647 A BR112014007647 A BR 112014007647A BR 112014007647 A BR112014007647 A BR 112014007647A BR 112014007647 A2 BR112014007647 A2 BR 112014007647A2
- Authority
- BR
- Brazil
- Prior art keywords
- hpdh
- polypeptide
- producing
- host cell
- isolated polynucleotide
- Prior art date
Links
- 230000000694 effects Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000000813 microbial effect Effects 0.000 title 1
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 230000009261 transgenic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01059—3-Hydroxypropionate dehydrogenase (1.1.1.59)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01276—Serine 3-dehydrogenase (1.1.1.276)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01298—3-Hydroxypropionate dehydrogenase (NADP+) (1.1.1.298)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/52—Improvements relating to the production of bulk chemicals using catalysts, e.g. selective catalysts
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161541363P | 2011-09-30 | 2011-09-30 | |
| PCT/US2012/057134 WO2013049073A1 (en) | 2011-09-30 | 2012-09-25 | Dehydrogenase variants and polynucleotides encoding same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014007647A2 true BR112014007647A2 (pt) | 2017-04-18 |
Family
ID=47016840
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014007647A BR112014007647A2 (pt) | 2011-09-30 | 2012-09-25 | “variante de 3-hpdh, polipeptídeo tendo atividade de 3-hpdh, polinucleotídeo isolado, célula hospedeira microbiana transgênica, e, método para produzir 3-hp |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US8728788B1 (forum.php) |
| EP (1) | EP2751261B1 (forum.php) |
| JP (3) | JP2014528726A (forum.php) |
| CN (1) | CN103857791B (forum.php) |
| AU (1) | AU2012316246B2 (forum.php) |
| BR (1) | BR112014007647A2 (forum.php) |
| CA (1) | CA2849303C (forum.php) |
| DK (1) | DK2751261T3 (forum.php) |
| IN (1) | IN2014CN03187A (forum.php) |
| WO (1) | WO2013049073A1 (forum.php) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2849303C (en) * | 2011-09-30 | 2019-09-17 | Novozymes, Inc. | Dehydrogenase variants and polynucleotides encoding same |
| WO2015017721A1 (en) | 2013-07-31 | 2015-02-05 | Novozymes A/S | 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase |
| US20180273915A1 (en) * | 2014-12-19 | 2018-09-27 | Novozymes A/S | Recombinant Host Cells For The Production Of 3-Hydroxypropionic Acid |
| WO2016154046A2 (en) | 2015-03-20 | 2016-09-29 | Verdezyne, Inc. | Biological methods for preparing 3-hydroxypropionic acid |
| US20180265902A1 (en) | 2015-08-24 | 2018-09-20 | Novozymes A/S | Beta-Alanine Aminotransferases For The Production of 3-Hydroxypropionic Acid |
| WO2023168244A1 (en) * | 2022-03-03 | 2023-09-07 | Cargill, Incorporated | Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate |
| WO2023168233A1 (en) * | 2022-03-03 | 2023-09-07 | Cargill, Incorporated | Genetically modified yeast and fermentation processes for the production of 3-hydroxypropionate |
| KR102782737B1 (ko) * | 2022-11-29 | 2025-03-19 | 씨제이제일제당 주식회사 | 신규한 프로피온알데하이드 디하이드로게나제 활성을 갖는 변이체 폴리펩티드 및 이의 용도 |
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| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| IL97645A (en) | 1990-03-23 | 1997-03-18 | Gist Brocades Nv | Production of enzymes in seeds and their use |
| US6395966B1 (en) | 1990-08-09 | 2002-05-28 | Dekalb Genetics Corp. | Fertile transgenic maize plants containing a gene encoding the pat protein |
| IL99552A0 (en) | 1990-09-28 | 1992-08-18 | Ixsys Inc | Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof |
| FR2704860B1 (fr) | 1993-05-05 | 1995-07-13 | Pasteur Institut | Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire. |
| DE4343591A1 (de) | 1993-12-21 | 1995-06-22 | Evotec Biosystems Gmbh | Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| CA2191718A1 (en) | 1994-06-03 | 1995-12-14 | Randy M. Berka | Phosphonyldipeptides useful in the treatment of cardiovascular diseases |
| JP3167729B2 (ja) | 1994-06-30 | 2001-05-21 | ノボ ノルディスク バイオテック，インコーポレイティド | 無毒、非毒素原性、非病原性の発現系、並びにその中で利用するためのプロモーター及びターミネーター |
| US5955310A (en) | 1998-02-26 | 1999-09-21 | Novo Nordisk Biotech, Inc. | Methods for producing a polypeptide in a bacillus cell |
| ATE332968T1 (de) | 1998-10-26 | 2006-08-15 | Novozymes As | Erstellung und durchmusterung von interessierenden dna-banken in zellen von filamentösen pilzen |
| CN1940067A (zh) | 1999-03-22 | 2007-04-04 | 诺沃奇梅兹有限公司 | 用于在真菌细胞中表达基因的启动子 |
| WO2001016346A1 (en) | 1999-08-30 | 2001-03-08 | Wisconsin Alumni Research Foundation | Production of 3-hydroxypropionic acid in recombinant organisms |
| CA2429039A1 (en) | 2000-11-20 | 2002-05-30 | Cargill, Incorporated | 3-hydroxypropionic acid and other organic compounds |
| US7151204B2 (en) | 2001-01-09 | 2006-12-19 | Monsanto Technology Llc | Maize chloroplast aldolase promoter compositions and methods for use thereof |
| ATE375388T1 (de) | 2001-07-27 | 2007-10-15 | Us Gov Health & Human Serv | Systeme zur stellengerichteten in-vivo-mutagenese mit oligonukleotiden |
| CA2473716A1 (en) | 2002-01-18 | 2003-07-31 | Cargill, Incorporated | Alanine 2,3- aminomutase |
| WO2003082795A2 (en) | 2002-03-25 | 2003-10-09 | Cargill, Incorporated | METHODS OF MANUFACTURING DERIVATIVES OF β-HYDROXYCARBOXYLIC ACIDS |
| ATE543873T1 (de) * | 2003-12-04 | 2012-02-15 | Novozymes As | Herstellung von 3-hydroxypropionsäure mittels beta-alanine-pyruvat-aminotrransferase |
| AU2004322803A1 (en) | 2004-07-30 | 2006-03-02 | Cargill, Incorporated | Alanine 2, 3 aminomutases |
| EP1805304A2 (en) | 2004-10-25 | 2007-07-11 | Codexis, Inc. | Improved alanine 2,3-aminomutases and related polynucleotides |
| DE102005048818A1 (de) | 2005-10-10 | 2007-04-12 | Degussa Ag | Mikrobiologische Herstellung von 3-Hydroxypropionsäure |
| BRPI0716212A2 (pt) * | 2006-08-30 | 2013-10-15 | Cargill Inc | Beta-alanina/alfa-cetoglutarato aminotransferase para produção de ácido 3-hidroxipropiônico |
| CA2675026A1 (en) | 2007-01-12 | 2008-07-24 | The Regents Of The University Of Colorado, A Body Corporate | Compositions and methods for enhancing tolerance for the production of organic chemicals produced by microorganisms |
| US8673601B2 (en) | 2007-01-22 | 2014-03-18 | Genomatica, Inc. | Methods and organisms for growth-coupled production of 3-hydroxypropionic acid |
| WO2009089457A1 (en) | 2008-01-11 | 2009-07-16 | Novozymes A/S | Methods for producing 3-hydroxypropionic acid and compounds thereof |
| US20100021978A1 (en) | 2008-07-23 | 2010-01-28 | Genomatica, Inc. | Methods and organisms for production of 3-hydroxypropionic acid |
| EP2326709A4 (en) | 2008-09-15 | 2013-01-23 | Opx Biotechnologies Inc | METHODS, SYSTEMS AND COMPOSITIONS RELATED TO REDUCED MICROBIAL PRODUCTION OF 3-HYDROXYPROPIONIC ACID (3-HP) IN ALDEHYDMETABOLITE |
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| CA2775390C (en) * | 2009-09-27 | 2021-06-29 | Opx Biotechnologies, Inc. | Method for producing 3-hydroxypropionic acid and other products |
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| WO2012074818A2 (en) | 2010-11-22 | 2012-06-07 | Novozymes, Inc. | Compositions and methods for 3-hydroxypropionic acid production |
| WO2013043758A2 (en) | 2011-09-19 | 2013-03-28 | Opx Biotechnologies, Inc. | Compositions and methods regarding direct nadh utilization to produce 3-hydroxypropionic acid, derived chemicals and further derived products |
| CA2849303C (en) * | 2011-09-30 | 2019-09-17 | Novozymes, Inc. | Dehydrogenase variants and polynucleotides encoding same |
-
2012
- 2012-09-25 CA CA2849303A patent/CA2849303C/en not_active Expired - Fee Related
- 2012-09-25 IN IN3187CHN2014 patent/IN2014CN03187A/en unknown
- 2012-09-25 AU AU2012316246A patent/AU2012316246B2/en not_active Ceased
- 2012-09-25 CN CN201280047868.6A patent/CN103857791B/zh not_active Expired - Fee Related
- 2012-09-25 BR BR112014007647A patent/BR112014007647A2/pt not_active Application Discontinuation
- 2012-09-25 EP EP12772176.9A patent/EP2751261B1/en not_active Not-in-force
- 2012-09-25 JP JP2014533652A patent/JP2014528726A/ja active Pending
- 2012-09-25 US US13/825,515 patent/US8728788B1/en active Active
- 2012-09-25 WO PCT/US2012/057134 patent/WO2013049073A1/en active Application Filing
- 2012-09-25 DK DK12772176.9T patent/DK2751261T3/en active
-
2014
- 2014-04-01 US US14/242,721 patent/US9163220B2/en active Active
-
2015
- 2015-10-05 US US14/875,452 patent/US9404091B2/en active Active
-
2017
- 2017-08-31 JP JP2017166889A patent/JP2018033457A/ja active Pending
-
2019
- 2019-03-13 JP JP2019046076A patent/JP2019110916A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012316246B2 (en) | 2017-10-26 |
| EP2751261A1 (en) | 2014-07-09 |
| US9163220B2 (en) | 2015-10-20 |
| CN103857791B (zh) | 2016-11-23 |
| JP2014528726A (ja) | 2014-10-30 |
| US9404091B2 (en) | 2016-08-02 |
| CA2849303C (en) | 2019-09-17 |
| WO2013049073A1 (en) | 2013-04-04 |
| US20140212938A1 (en) | 2014-07-31 |
| IN2014CN03187A (forum.php) | 2015-07-03 |
| US8728788B1 (en) | 2014-05-20 |
| JP2018033457A (ja) | 2018-03-08 |
| CA2849303A1 (en) | 2013-04-04 |
| US20160017296A1 (en) | 2016-01-21 |
| JP2019110916A (ja) | 2019-07-11 |
| AU2012316246A1 (en) | 2014-03-20 |
| DK2751261T3 (en) | 2018-12-10 |
| CN103857791A (zh) | 2014-06-11 |
| EP2751261B1 (en) | 2018-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according art. 34 industrial property law | ||
| B06T | Formal requirements before examination | ||
| B06A | Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |