BR112014006432B8 - Método in vitro para diagnosticar se um indivíduo tem ou não câncer, método implementado por computador, produto de programa de computador - Google Patents
Método in vitro para diagnosticar se um indivíduo tem ou não câncer, método implementado por computador, produto de programa de computadorInfo
- Publication number
- BR112014006432B8 BR112014006432B8 BR112014006432A BR112014006432A BR112014006432B8 BR 112014006432 B8 BR112014006432 B8 BR 112014006432B8 BR 112014006432 A BR112014006432 A BR 112014006432A BR 112014006432 A BR112014006432 A BR 112014006432A BR 112014006432 B8 BR112014006432 B8 BR 112014006432B8
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- lung cancer
- methods
- subjects
- subject
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 8
- 206010028980 Neoplasm Diseases 0.000 title abstract 6
- 201000011510 cancer Diseases 0.000 title abstract 6
- 238000000338 in vitro Methods 0.000 title abstract 2
- 238000004590 computer program Methods 0.000 title 1
- 239000000090 biomarker Substances 0.000 abstract 10
- 208000002154 non-small cell lung carcinoma Diseases 0.000 abstract 6
- 208000029729 tumor suppressor gene on chromosome 11 Diseases 0.000 abstract 6
- 206010058467 Lung neoplasm malignant Diseases 0.000 abstract 2
- 239000012472 biological sample Substances 0.000 abstract 2
- 201000005202 lung cancer Diseases 0.000 abstract 2
- 208000020816 lung neoplasm Diseases 0.000 abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57423—Specifically defined cancers of lung
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2011/057499 WO2013062515A2 (en) | 2011-10-24 | 2011-10-24 | Lung cancer biomarkers and uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| BR112014006432A2 BR112014006432A2 (pt) | 2017-04-04 |
| BR112014006432B1 BR112014006432B1 (pt) | 2021-04-06 |
| BR112014006432B8 true BR112014006432B8 (pt) | 2022-10-25 |
Family
ID=48168748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014006432A BR112014006432B8 (pt) | 2011-10-24 | 2011-10-24 | Método in vitro para diagnosticar se um indivíduo tem ou não câncer, método implementado por computador, produto de programa de computador |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2771692B1 (enExample) |
| JP (1) | JP5986638B2 (enExample) |
| KR (1) | KR101921945B1 (enExample) |
| CN (2) | CN103890586B (enExample) |
| AU (1) | AU2011378427B8 (enExample) |
| BR (1) | BR112014006432B8 (enExample) |
| CA (3) | CA2847188C (enExample) |
| ES (1) | ES2674318T3 (enExample) |
| IL (2) | IL231426A (enExample) |
| IN (1) | IN2014CN01787A (enExample) |
| MX (1) | MX355416B (enExample) |
| NZ (1) | NZ621733A (enExample) |
| SG (1) | SG11201400375SA (enExample) |
| WO (1) | WO2013062515A2 (enExample) |
| ZA (1) | ZA201401476B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX355020B (es) | 2010-07-09 | 2018-04-02 | Somalogic Inc | Biomarcadores de cancer de pulmon y usos de los mismos. |
| WO2014179959A1 (en) * | 2013-05-09 | 2014-11-13 | The Procter & Gamble Company | Method and system for assessing health condition |
| ES3014093T3 (en) | 2014-07-30 | 2025-04-16 | Harvard College | Method for determining nucleic acids |
| CN104263723B (zh) * | 2014-09-15 | 2017-06-06 | 南京医科大学 | 一种与原发性肺癌辅助诊断相关的低频高外显性遗传标志物及其应用 |
| WO2016094330A2 (en) * | 2014-12-08 | 2016-06-16 | 20/20 Genesystems, Inc | Methods and machine learning systems for predicting the liklihood or risk of having cancer |
| KR102087373B1 (ko) * | 2015-09-11 | 2020-03-10 | 주식회사 압타머사이언스 | 비소세포성 폐암 진단용 단백질 바이오마커 패널 및 이를 이용한 비소세포성 폐암 진단 방법 |
| KR102086935B1 (ko) * | 2015-11-05 | 2020-03-09 | 비지아이 션전 | 폐 선암종을 검출하기 위한 생체마커 및 그의 사용 |
| AU2017235661B2 (en) * | 2016-03-18 | 2023-06-08 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| KR101853118B1 (ko) * | 2016-09-02 | 2018-04-30 | 주식회사 바이오인프라생명과학 | 피험체의 폐암 진단을 위한 복합 바이오마커군, 이를 이용하는 폐암 진단용 키트, 복합 바이오마커군의 정보를 이용하는 방법 및 이를 수행하는 컴퓨팅 시스템 |
| EP4386761A3 (en) * | 2016-11-08 | 2024-09-04 | President and Fellows of Harvard College | Matrix imprinting and clearing |
| JP7128196B2 (ja) * | 2017-03-01 | 2022-08-30 | エフ.ホフマン-ラ ロシュ アーゲー | 検体の存在に関する生体サンプルの分類のためのシステムおよび方法 |
| US11788123B2 (en) | 2017-05-26 | 2023-10-17 | President And Fellows Of Harvard College | Systems and methods for high-throughput image-based screening |
| CN109116023B (zh) * | 2018-06-14 | 2021-06-04 | 郑州大学第一附属医院 | 一种肺癌标志物抗-mmp12自身抗体及其应用 |
| CN109470859A (zh) * | 2018-11-04 | 2019-03-15 | 华东医院 | 一种外泌体蛋白作为鉴别肺结节良恶性标志物及其应用 |
| CN113366116A (zh) | 2018-12-13 | 2021-09-07 | 哈佛学院院长及董事 | 用于merfish和其他应用的扩增方法和系统 |
| EP3671210A1 (en) * | 2018-12-21 | 2020-06-24 | Biosystems International KFT | Lung cancer protein epitomic biomarkers |
| WO2020167471A1 (en) * | 2019-02-15 | 2020-08-20 | Biodesix, Inc. | Predictive test for identification of early stage nsclc patients at high risk of recurrence after surgery |
| CN110473167B (zh) * | 2019-07-09 | 2022-06-17 | 哈尔滨工程大学 | 一种基于深度学习的尿沉渣图像识别系统及方法 |
| CN112892619B (zh) * | 2019-12-04 | 2022-07-15 | 香港城市大学深圳研究院 | 弧形边缘截面的pdms母模、微流控阀和芯片及其制备 |
| WO2022103843A1 (en) * | 2020-11-11 | 2022-05-19 | George Mason Research Foundation, Inc. | Laser capture microdissection visualization chemistry |
| KR102613772B1 (ko) * | 2021-02-02 | 2023-12-14 | 제노마인(주) | 폐암 혈액 바이오마커의 검출 방법 및 키트 |
| WO2025144995A1 (en) * | 2023-12-29 | 2025-07-03 | Novelna Inc. | Lung cancer detection proteins and methods of use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6335170B1 (en) * | 1999-02-22 | 2002-01-01 | Torben F. Orntoft | Gene expression in bladder tumors |
| US6596503B1 (en) * | 2000-08-18 | 2003-07-22 | East Carolina University | Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof |
| EP1787122B1 (en) * | 2004-08-10 | 2010-10-06 | Oncotherapy Science, Inc. | NON-SMALL CELL LUNG CANCER-RELATED GENE, ANLN, AND ITS INTERACTIONS WITH RhoA |
| WO2007013665A2 (en) * | 2005-07-27 | 2007-02-01 | Oncotherapy Science, Inc. | Method of diagnosing small cell lung cancer |
| EP1937837A2 (en) * | 2005-07-29 | 2008-07-02 | Siemens Healthcare Diagnostics Inc. | Methods and kits for the prediction of therapeutic success, recurrence free and overall survival in cancer therapies |
| US8445198B2 (en) * | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| US8014957B2 (en) * | 2005-12-15 | 2011-09-06 | Fred Hutchinson Cancer Research Center | Genes associated with progression and response in chronic myeloid leukemia and uses thereof |
| EP2090665A2 (en) * | 2006-10-20 | 2009-08-19 | Exiqon A/S | Novel human microRNAs associated with cancer |
| GB0803192D0 (en) * | 2008-02-22 | 2008-04-02 | Mubio Products Bv | SCLC biomarker panel |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| CA3011730C (en) * | 2008-09-09 | 2022-05-17 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| GB2512153B (en) | 2008-11-17 | 2014-11-12 | Veracyte Inc | Methods and compositions of molecular profiling for disease diagnostics |
| WO2010065940A1 (en) | 2008-12-04 | 2010-06-10 | The Regents Of The University Of California | Materials and methods for determining diagnosis and prognosis of prostate cancer |
| WO2011100472A1 (en) * | 2010-02-10 | 2011-08-18 | The Regents Of The University Of California | Salivary transcriptomic and proteomic biomarkers for breast cancer detection |
| CN103237901B (zh) | 2010-03-01 | 2016-08-03 | 卡里斯生命科学瑞士控股有限责任公司 | 用于治疗诊断的生物标志物 |
| CA2795776A1 (en) | 2010-04-06 | 2011-10-13 | Caris Life Sciences Luxembourg Holdings, S.A.R.L. | Circulating biomarkers for disease |
-
2011
- 2011-10-24 KR KR1020147013714A patent/KR101921945B1/ko active Active
- 2011-10-24 AU AU2011378427A patent/AU2011378427B8/en active Active
- 2011-10-24 CA CA2847188A patent/CA2847188C/en active Active
- 2011-10-24 CA CA3064363A patent/CA3064363C/en active Active
- 2011-10-24 MX MX2014004860A patent/MX355416B/es active IP Right Grant
- 2011-10-24 CN CN201180074349.4A patent/CN103890586B/zh active Active
- 2011-10-24 SG SG11201400375SA patent/SG11201400375SA/en unknown
- 2011-10-24 WO PCT/US2011/057499 patent/WO2013062515A2/en not_active Ceased
- 2011-10-24 CA CA3006793A patent/CA3006793C/en active Active
- 2011-10-24 BR BR112014006432A patent/BR112014006432B8/pt active IP Right Grant
- 2011-10-24 NZ NZ621733A patent/NZ621733A/en not_active IP Right Cessation
- 2011-10-24 CN CN201610457386.8A patent/CN106168624B/zh active Active
- 2011-10-24 JP JP2014538759A patent/JP5986638B2/ja active Active
- 2011-10-24 ES ES11874668.4T patent/ES2674318T3/es active Active
- 2011-10-24 EP EP11874668.4A patent/EP2771692B1/en active Active
- 2011-10-24 IN IN1787CHN2014 patent/IN2014CN01787A/en unknown
-
2014
- 2014-02-26 ZA ZA2014/01476A patent/ZA201401476B/en unknown
- 2014-03-10 IL IL231426A patent/IL231426A/en active IP Right Grant
-
2017
- 2017-05-08 IL IL252163A patent/IL252163A0/en unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/10/2011, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B25D | Requested change of name of applicant approved |
Owner name: SOMALOGIC OPERATING CO., INC. (US) |