BR112014002546A2 - "colágeno 7, ou seu fragmento funcional, seus métodos de produção e de purificação, sua preparação purificada ou isolada, vetor, coleção de vetores, preparação isolada de células, cultura celular, e método para produção de uma célula adequada à expressão de colágeno 7" - Google Patents
"colágeno 7, ou seu fragmento funcional, seus métodos de produção e de purificação, sua preparação purificada ou isolada, vetor, coleção de vetores, preparação isolada de células, cultura celular, e método para produção de uma célula adequada à expressão de colágeno 7"Info
- Publication number
- BR112014002546A2 BR112014002546A2 BR112014002546A BR112014002546A BR112014002546A2 BR 112014002546 A2 BR112014002546 A2 BR 112014002546A2 BR 112014002546 A BR112014002546 A BR 112014002546A BR 112014002546 A BR112014002546 A BR 112014002546A BR 112014002546 A2 BR112014002546 A2 BR 112014002546A2
- Authority
- BR
- Brazil
- Prior art keywords
- collagen
- cell
- preparation
- isolated
- functional fragments
- Prior art date
Links
- 102000008186 Collagen Human genes 0.000 title abstract 12
- 108010035532 Collagen Proteins 0.000 title abstract 12
- 229920001436 collagen Polymers 0.000 title abstract 12
- 239000012634 fragment Substances 0.000 title abstract 10
- 238000000034 method Methods 0.000 title abstract 8
- 239000013598 vector Substances 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title 2
- 238000004113 cell culture Methods 0.000 title 1
- 238000000746 purification Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 5
- 102000039446 nucleic acids Human genes 0.000 abstract 5
- 108020004707 nucleic acids Proteins 0.000 abstract 5
- 239000002253 acid Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/13—Dipeptidases (3.4.13)
- C12Y304/13009—Xaa-Pro dipeptidase (3.4.13.9) i.e. prolidase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/22—Vectors comprising a coding region that has been codon optimised for expression in a respective host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/485—Exopeptidases (3.4.11-3.4.19)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
- C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161514796P | 2011-08-03 | 2011-08-03 | |
| PCT/US2012/049553 WO2013020064A1 (en) | 2011-08-03 | 2012-08-03 | Collagen 7 and related methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112014002546A2 true BR112014002546A2 (pt) | 2017-03-14 |
Family
ID=47629706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112014002546A BR112014002546A2 (pt) | 2011-08-03 | 2012-08-03 | "colágeno 7, ou seu fragmento funcional, seus métodos de produção e de purificação, sua preparação purificada ou isolada, vetor, coleção de vetores, preparação isolada de células, cultura celular, e método para produção de uma célula adequada à expressão de colágeno 7" |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9676837B2 (https=) |
| EP (1) | EP2753704A4 (https=) |
| JP (2) | JP2014524241A (https=) |
| KR (1) | KR20140054160A (https=) |
| CN (2) | CN103842517A (https=) |
| AU (2) | AU2012289916B2 (https=) |
| BR (1) | BR112014002546A2 (https=) |
| CA (1) | CA2843896A1 (https=) |
| MX (1) | MX351565B (https=) |
| WO (1) | WO2013020064A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6849257B2 (en) | 2000-02-04 | 2005-02-01 | Children's Hospital Research Foundation | Lipid hydrolysis therapy for atherosclerosis and related diseases |
| FI3205351T3 (fi) | 2010-04-23 | 2023-07-06 | Alexion Pharma Inc | Lysosomaalisen kertymätaudin entsyymi |
| KR20150038636A (ko) | 2010-09-09 | 2015-04-08 | 시나게바 바이오파르마, 코포레이션 | 환자에서 리소좀 산 리파제 결핍증의 치료를 위한 리소좀 산 리파제의 용도 |
| WO2012112681A1 (en) | 2011-02-15 | 2012-08-23 | Shire Human Genetic Therapies, Inc. | Methods for treating lysosomal acid lipase deficiency |
| US9040484B2 (en) * | 2011-04-26 | 2015-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Production and delivery of a stable collagen |
| EP3099801B1 (en) | 2014-01-31 | 2020-03-18 | Factor Bioscience Inc. | Synthetic rna for use in the treatment of dystrophic epidermolysis bullosa |
| AU2015243535A1 (en) | 2014-04-08 | 2016-11-03 | University Of Southern California | Polypeptide compositions with Type VII collagen fibronectin Type Ill- like repeats and treatment methods for wound closure and healing |
| KR102204367B1 (ko) * | 2014-07-16 | 2021-01-19 | 주식회사 엘지생활건강 | 피부 주름 개선용 화장료 조성물 |
| CA2976376A1 (en) | 2015-02-13 | 2016-08-18 | Factor Bioscience Inc. | Nucleic acid products and methods of administration thereof |
| GB201601571D0 (en) * | 2016-01-28 | 2016-03-16 | Nordic Bioscience As | Collagen type Vll alpha 1 assay |
| MX2018011162A (es) * | 2016-03-16 | 2018-11-22 | Phoenix Tissue Repair Inc | Metodos de purificacion de colageno 7. |
| IL308824A (en) | 2016-08-17 | 2024-01-01 | Factor Bioscience Inc | Nucleic acid products and methods of administration thereof |
| US11028146B2 (en) * | 2017-09-22 | 2021-06-08 | Modern Meadow, Inc. | Recombinant yeast strains |
| US11180541B2 (en) | 2017-09-28 | 2021-11-23 | Geltor, Inc. | Recombinant collagen and elastin molecules and uses thereof |
| CN109022464A (zh) * | 2018-07-02 | 2018-12-18 | 西安巨子生物基因技术股份有限公司 | 重组人源型胶原蛋白的羟基化方法 |
| CN114401769A (zh) * | 2019-03-27 | 2022-04-26 | 菲尼克斯组织修复公司 | 生产胶原蛋白7组合物的系统和方法 |
| EP3953380A4 (en) | 2019-04-12 | 2023-01-25 | Geltor, Inc. | RECOMBINATION ELASTIN AND ASSOCIATED PRODUCTION |
| CA3145425A1 (en) | 2019-07-03 | 2021-01-07 | Factor Bioscience Inc. | Cationic lipids and uses thereof |
| US10501404B1 (en) | 2019-07-30 | 2019-12-10 | Factor Bioscience Inc. | Cationic lipids and transfection methods |
| GB2610313B (en) | 2020-01-24 | 2024-07-03 | Geltor Inc | Animal-free dietary collagen |
| KR20240004264A (ko) * | 2021-03-04 | 2024-01-11 | 젤라텍, 인크. | 배양된 동물 세포로부터의 콜라겐을 사용한 재료의 제조 방법 |
| MX2024004434A (es) | 2021-10-12 | 2024-07-09 | Phoenix Tissue Repair Inc | Terapia de reemplazo de proteínas con colágeno 7. |
| CN117143223B (zh) * | 2022-08-23 | 2024-03-08 | 山西锦波生物医药股份有限公司 | 一种生物合成人体结构性材料的制备方法 |
| CN116854807A (zh) * | 2023-07-26 | 2023-10-10 | 浙江大学 | 一种重组人源ⅶ型胶原蛋白及其制备方法与应用 |
| CN120137008B (zh) * | 2025-03-18 | 2025-09-26 | 广东普言生物科技有限公司 | 一种重组Ⅶ型胶原蛋白Pro.C7及其制备方法和应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020142391A1 (en) * | 1991-06-12 | 2002-10-03 | Kivirikko Kari I. | Synthesis of human procollagens and collagens in recombinant DNA systems |
| WO2001009318A1 (fr) * | 1999-07-29 | 2001-02-08 | Helix Research Institute | Genes associes au cancer du foie |
| US7026463B2 (en) * | 1999-08-13 | 2006-04-11 | Matthew Glenn | Polynucleotides and polypeptides, materials incorporating them and methods for using them |
| RU2002112751A (ru) | 1999-11-12 | 2004-02-27 | Файброджен, Инк. (Us) | Рекомбинантные желатины |
| CN1552889A (zh) * | 2003-12-18 | 2004-12-08 | 四川铭让生物科技有限公司 | 制备胶原蛋白和胶原多肽的方法及其用途 |
| JP4490498B2 (ja) | 2008-09-30 | 2010-06-23 | 新田ゼラチン株式会社 | 疾病抑制剤 |
| US9040484B2 (en) | 2011-04-26 | 2015-05-26 | The Board Of Trustees Of The Leland Stanford Junior University | Production and delivery of a stable collagen |
-
2012
- 2012-08-03 EP EP12820654.7A patent/EP2753704A4/en not_active Withdrawn
- 2012-08-03 AU AU2012289916A patent/AU2012289916B2/en not_active Ceased
- 2012-08-03 CA CA2843896A patent/CA2843896A1/en not_active Abandoned
- 2012-08-03 KR KR1020147005544A patent/KR20140054160A/ko not_active Ceased
- 2012-08-03 CN CN201280047084.3A patent/CN103842517A/zh active Pending
- 2012-08-03 CN CN201711271805.XA patent/CN108165593A/zh active Pending
- 2012-08-03 BR BR112014002546A patent/BR112014002546A2/pt not_active Application Discontinuation
- 2012-08-03 MX MX2014001383A patent/MX351565B/es active IP Right Grant
- 2012-08-03 WO PCT/US2012/049553 patent/WO2013020064A1/en not_active Ceased
- 2012-08-03 JP JP2014524112A patent/JP2014524241A/ja active Pending
- 2012-08-03 US US14/236,403 patent/US9676837B2/en active Active
-
2017
- 2017-09-07 JP JP2017171852A patent/JP2017209117A/ja not_active Abandoned
- 2017-11-02 AU AU2017254910A patent/AU2017254910A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2753704A1 (en) | 2014-07-16 |
| AU2017254910A1 (en) | 2017-11-23 |
| JP2017209117A (ja) | 2017-11-30 |
| CA2843896A1 (en) | 2013-02-07 |
| US20150011733A1 (en) | 2015-01-08 |
| MX351565B (es) | 2017-10-19 |
| CN108165593A (zh) | 2018-06-15 |
| AU2012289916A1 (en) | 2014-02-20 |
| MX2014001383A (es) | 2014-08-26 |
| KR20140054160A (ko) | 2014-05-08 |
| EP2753704A4 (en) | 2015-07-08 |
| US9676837B2 (en) | 2017-06-13 |
| AU2012289916B2 (en) | 2017-08-03 |
| CN103842517A (zh) | 2014-06-04 |
| JP2014524241A (ja) | 2014-09-22 |
| WO2013020064A1 (en) | 2013-02-07 |
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Legal Events
| Date | Code | Title | Description |
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| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06I | Publication of requirement cancelled [chapter 6.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 6.21 NA RPI NO 2539 DE 03/09/2019 POR TER SIDO INDEVIDA. |
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| B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
| B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |