BR112013022277A2 - método para produção de cadeia de açúcar contendo ácido siálico - Google Patents
método para produção de cadeia de açúcar contendo ácido siálicoInfo
- Publication number
- BR112013022277A2 BR112013022277A2 BR112013022277A BR112013022277A BR112013022277A2 BR 112013022277 A2 BR112013022277 A2 BR 112013022277A2 BR 112013022277 A BR112013022277 A BR 112013022277A BR 112013022277 A BR112013022277 A BR 112013022277A BR 112013022277 A2 BR112013022277 A2 BR 112013022277A2
- Authority
- BR
- Brazil
- Prior art keywords
- sialic acid
- sugar chain
- chain containing
- producing sugar
- containing sialic
- Prior art date
Links
- SQVRNKJHWKZAKO-UHFFFAOYSA-N beta-N-Acetyl-D-neuraminic acid Natural products CC(=O)NC1C(O)CC(O)(C(O)=O)OC1C(O)C(O)CO SQVRNKJHWKZAKO-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- SQVRNKJHWKZAKO-OQPLDHBCSA-N sialic acid Chemical compound CC(=O)N[C@@H]1[C@@H](O)C[C@@](O)(C(O)=O)OC1[C@H](O)[C@H](O)CO SQVRNKJHWKZAKO-OQPLDHBCSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/99—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- C12Y204/99001—Beta-galactoside alpha-2,6-sialyltransferase (2.4.99.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Materials Engineering (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011-047378 | 2011-03-04 | ||
| JP2011047378 | 2011-03-04 | ||
| PCT/JP2012/054727 WO2012121041A1 (ja) | 2011-03-04 | 2012-02-27 | シアル酸含有糖鎖の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013022277A2 true BR112013022277A2 (pt) | 2018-08-21 |
| BR112013022277B1 BR112013022277B1 (pt) | 2021-08-03 |
Family
ID=46798009
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013022277-8A BR112013022277B1 (pt) | 2011-03-04 | 2012-02-27 | Método para produção de cadeia de açúcar contendo ácido siálico |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9376506B2 (pt) |
| EP (1) | EP2682473B1 (pt) |
| JP (1) | JP5975577B2 (pt) |
| KR (1) | KR101906623B1 (pt) |
| CN (1) | CN103502462B (pt) |
| AU (1) | AU2012225900B2 (pt) |
| BR (1) | BR112013022277B1 (pt) |
| CA (1) | CA2828905C (pt) |
| RU (1) | RU2597975C2 (pt) |
| SG (1) | SG193021A1 (pt) |
| TW (1) | TWI546385B (pt) |
| WO (1) | WO2012121041A1 (pt) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6090738B2 (ja) * | 2011-12-19 | 2017-03-08 | 国立大学法人 香川大学 | 糖ペプチドの製造方法、糖アミノ酸の製造方法および糖タンパク質の製造方法 |
| SG10201707565WA (en) * | 2013-03-14 | 2017-10-30 | Glycobia Inc | Oligosaccharide compositions, glycoproteins and methods to produce the same in prokaryotes |
| US10450361B2 (en) | 2013-03-15 | 2019-10-22 | Momenta Pharmaceuticals, Inc. | Methods related to CTLA4-Fc fusion proteins |
| WO2014179601A2 (en) * | 2013-05-02 | 2014-11-06 | Momenta Pharmaceuticals, Inc. | Sialylated glycoproteins |
| US10464996B2 (en) | 2013-05-13 | 2019-11-05 | Momenta Pharmaceuticals, Inc. | Methods for the treatment of neurodegeneration |
| US20160257754A1 (en) | 2013-10-16 | 2016-09-08 | Momenta Pharmaceuticals Inc. | Sialylated glycoproteins |
| KR101755430B1 (ko) * | 2014-09-25 | 2017-07-27 | 한국생명공학연구원 | 개선된 효율을 갖는 시알산전달효소를 이용한 당단백질의 당사슬에 시알산을 부가하는 방법 |
| EP3237608B1 (en) * | 2014-12-22 | 2019-10-09 | F. Hoffmann-La Roche AG | Cmp-dependent sialidase activity |
| TWI757238B (zh) * | 2015-06-30 | 2022-03-11 | 日商糖鎖工學研究所股份有限公司 | 白蛋白-糖鏈複合物 |
| JP6762027B2 (ja) | 2016-08-25 | 2020-09-30 | 株式会社雅嘉貿易 | シアロオリゴ糖の製造方法とその利用 |
| WO2020096057A1 (ja) * | 2018-11-08 | 2020-05-14 | 日立化成テクノサービス株式会社 | メタボロームの分離方法 |
| JP7341434B2 (ja) * | 2018-11-08 | 2023-09-11 | 株式会社レゾナック・テクノサービス | メタボローム分析用分離材及びメタボローム分析用カラム |
| CN110041443A (zh) * | 2019-04-24 | 2019-07-23 | 广东药科大学附属第一医院 | 多分支聚唾液酸衍生物及其制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2125092C1 (ru) * | 1991-10-15 | 1999-01-20 | Дзе Скриппс Рисерч Инститьют | Способ получения фукозилированного углевода, способ получения фукозилированной сиалилированной углеводной молекулы, реакционная система in vitro |
| US6458574B1 (en) * | 1996-09-12 | 2002-10-01 | Transkaryotic Therapies, Inc. | Treatment of a α-galactosidase a deficiency |
| WO2001088117A2 (en) * | 2000-05-12 | 2001-11-22 | Neose Technologies, Inc. | In vitro fucosylation recombinant glycopeptides |
| ATE420198T1 (de) | 2002-04-26 | 2009-01-15 | Kirin Pharma Kk | Methylotrophe hefe,die eine zuckerkette eines säugers herstellt |
| AU2003292641B2 (en) * | 2002-12-26 | 2007-11-29 | Glytech, Inc. | Three-branched sugar-chain asparagine derivatives, the sugar-chain asparagines, the sugar chains, and processes for producing these |
| JP4910091B2 (ja) * | 2005-02-16 | 2012-04-04 | 国立大学法人北海道大学 | ４位ハロゲン化ガラクトース含有糖鎖及びその応用 |
| US7461223B2 (en) | 2006-05-29 | 2008-12-02 | Microsoft Corporation | Retaining shadow copy data during replication |
| EP2411529A4 (en) * | 2009-03-27 | 2012-09-19 | Zacharon Pharmaceuticals Inc | MODULATORS OF BIOSYNTHESIS OF N-BOUND GLYCANS |
| CN103946234B (zh) * | 2011-09-04 | 2017-06-30 | 株式会社糖锁工学研究所 | 附加糖链的多肽和含有该多肽的医药组合物 |
-
2012
- 2012-02-27 AU AU2012225900A patent/AU2012225900B2/en not_active Ceased
- 2012-02-27 JP JP2013503458A patent/JP5975577B2/ja active Active
- 2012-02-27 BR BR112013022277-8A patent/BR112013022277B1/pt not_active IP Right Cessation
- 2012-02-27 SG SG2013066527A patent/SG193021A1/en unknown
- 2012-02-27 CN CN201280011234.5A patent/CN103502462B/zh not_active Expired - Fee Related
- 2012-02-27 WO PCT/JP2012/054727 patent/WO2012121041A1/ja active Application Filing
- 2012-02-27 US US14/002,645 patent/US9376506B2/en active Active
- 2012-02-27 CA CA2828905A patent/CA2828905C/en active Active
- 2012-02-27 RU RU2013143650/10A patent/RU2597975C2/ru active
- 2012-02-27 EP EP12754383.3A patent/EP2682473B1/en active Active
- 2012-02-27 KR KR1020137024893A patent/KR101906623B1/ko active IP Right Grant
- 2012-03-03 TW TW101107162A patent/TWI546385B/zh not_active IP Right Cessation
-
2015
- 2015-05-01 US US14/702,535 patent/US20170240655A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN103502462B (zh) | 2016-08-10 |
| US20140066617A1 (en) | 2014-03-06 |
| CN103502462A (zh) | 2014-01-08 |
| US9376506B2 (en) | 2016-06-28 |
| TW201247873A (en) | 2012-12-01 |
| EP2682473A1 (en) | 2014-01-08 |
| RU2597975C2 (ru) | 2016-09-20 |
| JPWO2012121041A1 (ja) | 2014-07-17 |
| EP2682473B1 (en) | 2019-09-25 |
| US20170240655A1 (en) | 2017-08-24 |
| KR101906623B1 (ko) | 2018-10-10 |
| AU2012225900A1 (en) | 2013-09-19 |
| AU2012225900B2 (en) | 2015-09-17 |
| RU2013143650A (ru) | 2015-04-10 |
| WO2012121041A1 (ja) | 2012-09-13 |
| CA2828905C (en) | 2021-05-04 |
| SG193021A1 (en) | 2013-09-30 |
| EP2682473A4 (en) | 2015-06-03 |
| BR112013022277B1 (pt) | 2021-08-03 |
| TWI546385B (zh) | 2016-08-21 |
| JP5975577B2 (ja) | 2016-08-23 |
| CA2828905A1 (en) | 2012-09-13 |
| KR20140114279A (ko) | 2014-09-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 27/02/2012, OBSERVADAS AS CONDICOES LEGAIS. |
|
| B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B24J | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12) |
Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2763 DE 19-12-2023 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |