BR112013018642A2 - vacinas e composições contra streptococcus pneumoniae - Google Patents
vacinas e composições contra streptococcus pneumoniaeInfo
- Publication number
- BR112013018642A2 BR112013018642A2 BR112013018642-9A BR112013018642A BR112013018642A2 BR 112013018642 A2 BR112013018642 A2 BR 112013018642A2 BR 112013018642 A BR112013018642 A BR 112013018642A BR 112013018642 A2 BR112013018642 A2 BR 112013018642A2
- Authority
- BR
- Brazil
- Prior art keywords
- streptococcus pneumoniae
- compositions
- pneumoniae vaccines
- vaccines
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Abstract
formulação de vacina contra streptococcus pneumoniae a presente invenção refere-se a streptococcus pneumoniae que é uma grande preocupação de saúde, em especial em 5 pacientes muito novos, idosos, ou imunocomprometidos. a presente divulgação provê, inter alia, certas vacinas e composições farmacêuticas altamente eficazes contra streptococcus pneumoniae. os antígenos podem ser usados de modo terapêutico ou profilático.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161434818P | 2011-01-20 | 2011-01-20 | |
US61/434,818 | 2011-01-20 | ||
PCT/US2012/022128 WO2012100234A1 (en) | 2011-01-20 | 2012-01-20 | Vaccines and compositions against streptococcus pneumoniae |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112013018642A2 true BR112013018642A2 (pt) | 2019-04-30 |
Family
ID=46516136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112013018642-9A BR112013018642A2 (pt) | 2011-01-20 | 2012-01-20 | vacinas e composições contra streptococcus pneumoniae |
Country Status (14)
Country | Link |
---|---|
US (2) | US9393294B2 (pt) |
EP (1) | EP2665490B1 (pt) |
JP (1) | JP6126993B2 (pt) |
KR (1) | KR20140017554A (pt) |
CN (2) | CN105833260A (pt) |
AU (2) | AU2012207089B2 (pt) |
BR (1) | BR112013018642A2 (pt) |
CA (1) | CA2861313A1 (pt) |
IL (1) | IL227554A (pt) |
MX (1) | MX344120B (pt) |
MY (1) | MY163871A (pt) |
RU (1) | RU2623174C2 (pt) |
SG (2) | SG192060A1 (pt) |
WO (2) | WO2012100234A1 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011008548A1 (en) * | 2009-06-29 | 2011-01-20 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
WO2011112906A2 (en) | 2010-03-12 | 2011-09-15 | Children's Medical Center Corporation | Novel immunogens and methods for discovery and screening thereof |
MY163871A (en) | 2011-01-20 | 2017-10-31 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
EP2804627B1 (en) * | 2012-01-20 | 2019-08-14 | Genocea Biosciences Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
CA2900008A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
WO2014210031A1 (en) * | 2013-06-25 | 2014-12-31 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
KR101587859B1 (ko) * | 2013-09-11 | 2016-01-25 | 한국기초과학지원연구원 | 폐렴연쇄상구균의 NagA 단백질을 포함하는 폐렴연쇄상구균의 감염 진단용 조성물 |
RU2737638C2 (ru) * | 2013-12-03 | 2020-12-01 | Вирометикс Аг | ПРОЛИН-БОГАТЫЕ ПЕПТИДЫ, ЗАЩИЩАЮЩИЕ ОТ S.pneumoniae |
CN106822885B (zh) | 2017-02-16 | 2020-06-30 | 清华大学 | 肺炎链球菌疫苗 |
GB201807380D0 (en) | 2018-05-04 | 2018-06-20 | Karlsson Roger | Biomarkers for detecting microbial infection |
BR112021004193A2 (pt) | 2018-09-12 | 2021-05-25 | Affinivax, Inc. | vacinas pneumocócicas multivalentes |
RU2701733C1 (ru) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Живая вакцина на основе штамма пробиотиков ENTEROCOCCUS FAECIUM L3 для профилактики инфекции, вызванной STREPTOCOCCUS PNEUMONIE |
Family Cites Families (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2059692C (en) | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
US5371197A (en) | 1991-09-24 | 1994-12-06 | Merck & Co., Inc. | Protein-dimeric polysaccharide conjugate vaccine |
US5474905A (en) * | 1993-11-24 | 1995-12-12 | Research Corporation Technologies | Antibodies specific for streptococcus pneumoniae hemin/hemoglobin-binding antigens |
US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
JP2000511769A (ja) | 1996-04-02 | 2000-09-12 | スミスクライン・ビーチャム・コーポレイション | 新規化合物 |
AU5194598A (en) | 1996-10-31 | 1998-05-22 | Human Genome Sciences, Inc. | (streptococcus pneumoniae) antigens and vaccines |
WO1998050555A2 (en) | 1997-05-06 | 1998-11-12 | Human Genome Sciences, Inc. | Enterococcus faecalis polynucleotides and polypeptides |
WO1998059071A1 (en) | 1997-06-20 | 1998-12-30 | Human Genome Sciences, Inc. | Lyme disease vaccines |
US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US7129340B1 (en) | 1997-07-02 | 2006-10-31 | sanofi pasteur limited/sanofi pasteur limitée | Nucleic acid and amino acid sequences relating to streptococcus pneumoniae for diagnostics and therapeutics |
US5882885A (en) | 1997-07-17 | 1999-03-16 | Smithkline Beecham Corporation | Glycogen phosphorylase |
US5994101A (en) | 1997-07-18 | 1999-11-30 | Smithkline Beecham Corporation | DNA encoding gidA1 polypeptides |
US6617156B1 (en) | 1997-08-15 | 2003-09-09 | Lynn A. Doucette-Stamm | Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics |
US6248558B1 (en) | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
GB9816337D0 (en) * | 1998-07-27 | 1998-09-23 | Cortecs Uk Ltd | Proteins |
EP1144640A3 (en) | 1998-07-27 | 2001-11-28 | Microbial Technics Limited | Nucleic acids and proteins from streptococcus pneumoniae |
DE69938670D1 (de) * | 1998-12-23 | 2008-06-19 | Id Biomedical Corp | Streptococcus antigene |
ES2360296T3 (es) | 1999-06-10 | 2011-06-02 | Medimmune, Llc | Vacunas y proteínas de setreptococcus pneumoniae. |
US6887480B1 (en) | 1999-06-10 | 2005-05-03 | Medimmune, Inc. | Streptococcus pneumoniae proteins and vaccines |
NZ519669A (en) | 1999-12-23 | 2004-03-26 | Vmax Ltd | Streptococcus pyogenes virulence genes and proteins and their use |
US6783939B2 (en) | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
NZ560966A (en) | 2000-10-27 | 2010-06-25 | Novartis Vaccines & Diagnostic | Nucleic acids and proteins from streptococcus groups A & B |
GB0107658D0 (en) * | 2001-03-27 | 2001-05-16 | Chiron Spa | Streptococcus pneumoniae |
MXPA03009415A (es) | 2001-04-16 | 2004-01-29 | Wyeth Corp | ESTRUCTURAS NOVEDOSAS DE LECTURA ABIERTA DE STREPTOCOCCUS PNEUMONIAE QUE CODIFICAN ANTIGENOS DE POLIPePTIDOS Y USOS DE LAS MISMAS. |
US20040029129A1 (en) | 2001-10-25 | 2004-02-12 | Liangsu Wang | Identification of essential genes in microorganisms |
US7314974B2 (en) | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
AU2003242955B2 (en) | 2002-04-02 | 2009-04-09 | Ben-Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
US20090252756A1 (en) | 2002-04-02 | 2009-10-08 | Yaffa Mizrachi-Nebenzahl | Protein-based streptococcus pneumoniae vaccines |
US20070053924A1 (en) | 2002-08-26 | 2007-03-08 | Herve Tettelin | Conserved and specific streptococcal genomes |
AU2003268353A1 (en) | 2002-08-30 | 2004-03-19 | Tufts University | Streptococcus pneumoniae antigens for diagnosis, treatment and prevention of active infection |
EP1545468A4 (en) | 2002-09-20 | 2007-06-20 | Alpharma Inc | SUSTAINED RELEASE OPIOID PREPARATIONS AND METHODS OF USE |
AU2004230244B2 (en) | 2003-04-15 | 2011-09-22 | Intercell Ag | S. pneumoniae antigens |
GB0318688D0 (en) | 2003-08-08 | 2003-09-10 | Chiron Srl | Streptococcus pneumoniae knockout mutants |
JP2008525033A (ja) | 2004-12-22 | 2008-07-17 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | B群連鎖球菌 |
KR20070122458A (ko) | 2005-02-11 | 2007-12-31 | 에이스 바이오사이언시즈 에이/에스 | 표재성 스트렙토코커스 뉴모니아 폴리펩티드 |
WO2007106407A2 (en) | 2006-03-10 | 2007-09-20 | Wyeth | Microarray for monitoring gene expression in multiple strains of streptococcus pneumoniae |
EP2035035A2 (en) | 2006-06-09 | 2009-03-18 | Novartis AG | Immunogenic compositions for streptococcus agalactiae |
GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
WO2008119358A2 (en) | 2007-03-30 | 2008-10-09 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides for use in vaccine compositions |
WO2009011971A2 (en) | 2007-05-18 | 2009-01-22 | The Govt. Of The U.S.A. As Represented By The Secretary Of The Dept. Of Health And Human Services, Centers For Disease Control And Prevention | Primers and probes for the detection of streptococcus pneumoniae |
EP2167531B1 (en) | 2007-05-25 | 2012-03-21 | Novartis AG | Streptococcus pneumoniae pilus antigens |
WO2008150885A1 (en) | 2007-05-29 | 2008-12-11 | Board Of Regents, The University Of Texas System | Modulation of the th-17 cell mediated immune responses |
GB0714963D0 (en) * | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
EP2225265A2 (en) | 2007-09-14 | 2010-09-08 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
US7833776B2 (en) | 2007-12-12 | 2010-11-16 | National Health Research Institutes | Lipidating sequences and use thereof for producing lipidated proteins in E. coli |
US8466259B2 (en) | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
EA201591888A1 (ru) | 2008-03-14 | 2016-05-31 | Санофи Пастер Байолоджикс Ко. | Репликационно-дефектные вакцины и вакцинные векторы против флавивирусов |
ES2845203T3 (es) | 2008-07-01 | 2021-07-26 | Genocea Biosciences Inc | Sistema de análisis de antígenos |
BRPI0922132A2 (pt) | 2008-12-03 | 2018-10-23 | Protea Vaccine Tech Ltd | fragmentos glutamil trna sintetase (gts). |
US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
EP2445927B1 (en) | 2009-06-22 | 2014-04-23 | National Health Research Institutes | Lipidated tumor- associated antigens and immunotherapeutic compositions |
WO2010150242A2 (en) | 2009-06-25 | 2010-12-29 | Protea Vaccine Technologies Ltd. | Immunogenic streptococcus pneumoniae peptides and peptide-multimers |
WO2011008548A1 (en) * | 2009-06-29 | 2011-01-20 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
WO2011064781A1 (en) | 2009-11-30 | 2011-06-03 | Ben-Gurion University Of The Negev Research And Development Authority | S. pneumoniae adhesins |
WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
JP5065434B2 (ja) | 2010-04-06 | 2012-10-31 | 株式会社日立製作所 | 管理方法及び管理装置 |
WO2011128892A2 (en) | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Modified forms of pneumococcal surface immunogenic protein b (psipb) |
WO2011141968A1 (en) | 2010-05-14 | 2011-11-17 | Hitachi, Ltd. | Storage apparatus and data retaining method for storage apparatus |
MY163871A (en) | 2011-01-20 | 2017-10-31 | Genocea Biosciences Inc | Vaccines and compositions against streptococcus pneumoniae |
-
2012
- 2012-01-20 MY MYPI2013002729A patent/MY163871A/en unknown
- 2012-01-20 SG SG2013055496A patent/SG192060A1/en unknown
- 2012-01-20 BR BR112013018642-9A patent/BR112013018642A2/pt not_active Application Discontinuation
- 2012-01-20 JP JP2013550649A patent/JP6126993B2/ja not_active Expired - Fee Related
- 2012-01-20 CN CN201610211251.3A patent/CN105833260A/zh active Pending
- 2012-01-20 AU AU2012207089A patent/AU2012207089B2/en not_active Ceased
- 2012-01-20 MX MX2013008358A patent/MX344120B/es active IP Right Grant
- 2012-01-20 AU AU2012207088A patent/AU2012207088A1/en not_active Abandoned
- 2012-01-20 KR KR1020137021818A patent/KR20140017554A/ko not_active Application Discontinuation
- 2012-01-20 RU RU2013138563A patent/RU2623174C2/ru not_active IP Right Cessation
- 2012-01-20 EP EP12736908.0A patent/EP2665490B1/en active Active
- 2012-01-20 US US13/355,468 patent/US9393294B2/en active Active
- 2012-01-20 SG SG10201600435UA patent/SG10201600435UA/en unknown
- 2012-01-20 CA CA2861313A patent/CA2861313A1/en not_active Abandoned
- 2012-01-20 WO PCT/US2012/022128 patent/WO2012100234A1/en active Application Filing
- 2012-01-20 WO PCT/US2012/022127 patent/WO2012100233A1/en active Application Filing
- 2012-01-20 CN CN201280006067.5A patent/CN103501809B/zh not_active Expired - Fee Related
-
2013
- 2013-07-18 IL IL227554A patent/IL227554A/en active IP Right Grant
-
2016
- 2016-06-13 US US15/180,844 patent/US10188717B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
KR20140017554A (ko) | 2014-02-11 |
WO2012100233A1 (en) | 2012-07-26 |
RU2623174C2 (ru) | 2017-06-22 |
CN105833260A (zh) | 2016-08-10 |
MY163871A (en) | 2017-10-31 |
AU2012207089A1 (en) | 2013-05-02 |
MX344120B (es) | 2016-12-06 |
EP2665490A4 (en) | 2015-07-01 |
EP2665490A1 (en) | 2013-11-27 |
CA2861313A1 (en) | 2012-07-26 |
MX2013008358A (es) | 2013-09-02 |
AU2012207088A1 (en) | 2013-05-02 |
NZ614460A (en) | 2015-08-28 |
CN103501809B (zh) | 2018-08-10 |
US20170157234A1 (en) | 2017-06-08 |
US9393294B2 (en) | 2016-07-19 |
CN103501809A (zh) | 2014-01-08 |
WO2012100234A1 (en) | 2012-07-26 |
IL227554A0 (en) | 2013-09-30 |
US20120189649A1 (en) | 2012-07-26 |
JP2014503002A (ja) | 2014-02-06 |
SG192060A1 (en) | 2013-08-30 |
JP6126993B2 (ja) | 2017-05-10 |
EP2665490B1 (en) | 2020-03-04 |
RU2013138563A (ru) | 2015-02-27 |
US10188717B2 (en) | 2019-01-29 |
SG10201600435UA (en) | 2016-02-26 |
IL227554A (en) | 2016-10-31 |
AU2012207089B2 (en) | 2016-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B15I | Others concerning applications: loss of priority |
Free format text: PERDA DA PRIORIDADE US 61/434,818 DE 20/01/2011 POR NAO CUMPRIMENTO DE EXIGENCIA REFERENTE A COMPROVACAO DE DIREITO DE PRIORIDADE. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
|
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |