EP2665490A4 - Vaccines and compositions against streptococcus pneumoniae - Google Patents
Vaccines and compositions against streptococcus pneumoniaeInfo
- Publication number
- EP2665490A4 EP2665490A4 EP12736908.0A EP12736908A EP2665490A4 EP 2665490 A4 EP2665490 A4 EP 2665490A4 EP 12736908 A EP12736908 A EP 12736908A EP 2665490 A4 EP2665490 A4 EP 2665490A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- vaccines
- streptococcus pneumoniae
- compositions against
- against streptococcus
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000193998 Streptococcus pneumoniae Species 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940031000 streptococcus pneumoniae Drugs 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161434818P | 2011-01-20 | 2011-01-20 | |
PCT/US2012/022128 WO2012100234A1 (en) | 2011-01-20 | 2012-01-20 | Vaccines and compositions against streptococcus pneumoniae |
Publications (3)
Publication Number | Publication Date |
---|---|
EP2665490A1 EP2665490A1 (en) | 2013-11-27 |
EP2665490A4 true EP2665490A4 (en) | 2015-07-01 |
EP2665490B1 EP2665490B1 (en) | 2020-03-04 |
Family
ID=46516136
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP12736908.0A Active EP2665490B1 (en) | 2011-01-20 | 2012-01-20 | Vaccines and compositions against streptococcus pneumoniae |
Country Status (14)
Country | Link |
---|---|
US (2) | US9393294B2 (en) |
EP (1) | EP2665490B1 (en) |
JP (1) | JP6126993B2 (en) |
KR (1) | KR20140017554A (en) |
CN (2) | CN103501809B (en) |
AU (2) | AU2012207088A1 (en) |
BR (1) | BR112013018642A2 (en) |
CA (1) | CA2861313A1 (en) |
IL (1) | IL227554A (en) |
MX (1) | MX344120B (en) |
MY (1) | MY163871A (en) |
RU (1) | RU2623174C2 (en) |
SG (2) | SG192060A1 (en) |
WO (2) | WO2012100233A1 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011008548A1 (en) | 2009-06-29 | 2011-01-20 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
EP2550289A4 (en) | 2010-03-12 | 2013-11-27 | Childrens Medical Center | Novel immunogens and methods for discovery and screening thereof |
RU2623174C2 (en) | 2011-01-20 | 2017-06-22 | Дженоцея Байосайенсиз, Инк. | Vaccines and composition against streptococcus pneumoniae |
CA2897020A1 (en) * | 2012-01-20 | 2013-07-25 | Genocea Biosciences, Inc. | Fused antigen vaccines and compositions against streptococcus pneumoniae |
CA2900008A1 (en) | 2013-02-07 | 2014-08-14 | Children's Medical Center Corporation | Protein antigens that provide protection against pneumococcal colonization and/or disease |
US10126305B2 (en) * | 2013-06-25 | 2018-11-13 | University of Pittsburg—Of the Commonwealth System of Higher Education | Proteomic biomarkers of sepsis in elderly patients |
KR101587859B1 (en) * | 2013-09-11 | 2016-01-25 | 한국기초과학지원연구원 | Composition for diagnosing infection of streptococcus pneumoniae comprising N-aceylglucosamine-6-phosphate deacetylase of streptococcus pneumoniae |
WO2015082501A1 (en) | 2013-12-03 | 2015-06-11 | Virometix Ag | Proline-rich peptides protective against s. pneumoniae |
CN106822885B (en) | 2017-02-16 | 2020-06-30 | 清华大学 | Streptococcus pneumoniae vaccine |
GB201807380D0 (en) * | 2018-05-04 | 2018-06-20 | Karlsson Roger | Biomarkers for detecting microbial infection |
CN112969474A (en) | 2018-09-12 | 2021-06-15 | 艾芬尼维克斯公司 | Multivalent pneumococcal vaccine |
RU2701733C1 (en) * | 2018-12-14 | 2019-10-01 | Федеральное государственное бюджетное научное учреждение "Институт экспериментальной медицины" (ФГБНУ "ИЭМ") | Live vaccine based on enterococcus faecium l3 probiotic strain for prevention of infection caused by streptococcus pneumonie |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002077021A2 (en) * | 2001-03-27 | 2002-10-03 | Chiron Srl. | Streptococcus pneumoniae proteins and nucleic acids |
WO2011008548A1 (en) * | 2009-06-29 | 2011-01-20 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
Family Cites Families (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2059692C (en) * | 1991-01-28 | 2004-11-16 | Peter J. Kniskern | Pneumoccoccal polysaccharide conjugate vaccine |
US5371197A (en) | 1991-09-24 | 1994-12-06 | Merck & Co., Inc. | Protein-dimeric polysaccharide conjugate vaccine |
US5474905A (en) * | 1993-11-24 | 1995-12-12 | Research Corporation Technologies | Antibodies specific for streptococcus pneumoniae hemin/hemoglobin-binding antigens |
US5505947A (en) | 1994-05-27 | 1996-04-09 | The University Of North Carolina At Chapel Hill | Attenuating mutations in Venezuelan Equine Encephalitis virus |
WO1997037026A1 (en) | 1996-04-02 | 1997-10-09 | Smithkline Beecham Corporation | Novel compounds |
WO1998018931A2 (en) | 1996-10-31 | 1998-05-07 | Human Genome Sciences, Inc. | Streptococcus pneumoniae polynucleotides and sequences |
WO1998050554A2 (en) | 1997-05-06 | 1998-11-12 | Human Genome Sciences, Inc. | Enterococcus faecalis polynucleotides and polypeptides |
AU8151898A (en) | 1997-06-20 | 1999-01-04 | Human Genome Sciences, Inc. | Lyme disease vaccines |
US7153952B1 (en) | 1997-07-02 | 2006-12-26 | sanofi pasteur limited/sanofi pasteur limitée | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US6800744B1 (en) | 1997-07-02 | 2004-10-05 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics |
US5882885A (en) | 1997-07-17 | 1999-03-16 | Smithkline Beecham Corporation | Glycogen phosphorylase |
US5994101A (en) | 1997-07-18 | 1999-11-30 | Smithkline Beecham Corporation | DNA encoding gidA1 polypeptides |
US6617156B1 (en) | 1997-08-15 | 2003-09-09 | Lynn A. Doucette-Stamm | Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics |
US6248558B1 (en) | 1998-03-31 | 2001-06-19 | Vanderbilt University | Sequence and method for genetic engineering of proteins with cell membrane translocating activity |
WO2000006738A2 (en) | 1998-07-27 | 2000-02-10 | Microbial Technics Limited | NUCLEIC ACIDS AND PROTEINS FROM $i(STREPTOCOCCUS PNEUMONIAE) |
GB9816337D0 (en) * | 1998-07-27 | 1998-09-23 | Cortecs Uk Ltd | Proteins |
PT2261358E (en) | 1998-12-23 | 2014-07-30 | Id Biomedical Corp Quebec | Novel streptococcus antigen |
ATE325620T1 (en) | 1999-06-10 | 2006-06-15 | Medimmune Inc | STREPTOCOCCUS PNEUMONIAE PROTEINS AND VACCINES |
US6887480B1 (en) | 1999-06-10 | 2005-05-03 | Medimmune, Inc. | Streptococcus pneumoniae proteins and vaccines |
NZ519669A (en) | 1999-12-23 | 2004-03-26 | Vmax Ltd | Streptococcus pyogenes virulence genes and proteins and their use |
US6783939B2 (en) | 2000-07-07 | 2004-08-31 | Alphavax, Inc. | Alphavirus vectors and virosomes with modified HIV genes for use in vaccines |
EP2189473A3 (en) | 2000-10-27 | 2010-08-11 | Novartis Vaccines and Diagnostics S.r.l. | Nucleic and proteins from streptococcus groups A & B |
CA2444133A1 (en) | 2001-04-16 | 2002-10-24 | Wyeth Holdings Corporation | Novel streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof |
US20040029129A1 (en) | 2001-10-25 | 2004-02-12 | Liangsu Wang | Identification of essential genes in microorganisms |
US7314974B2 (en) | 2002-02-21 | 2008-01-01 | Monsanto Technology, Llc | Expression of microbial proteins in plants for production of plants with improved properties |
EP2275122A3 (en) | 2002-04-02 | 2011-05-18 | Ben Gurion University Of The Negev Research And Development Authority | Protein-based streptococcus pneumoniae vaccines |
US20090252756A1 (en) | 2002-04-02 | 2009-10-08 | Yaffa Mizrachi-Nebenzahl | Protein-based streptococcus pneumoniae vaccines |
EP1597348A4 (en) | 2002-08-26 | 2010-03-31 | Novartis Vaccines & Diagnostic | Conserved and specific streptococcal genomes |
AU2003268353A1 (en) | 2002-08-30 | 2004-03-19 | Tufts University | Streptococcus pneumoniae antigens for diagnosis, treatment and prevention of active infection |
CA2498798A1 (en) | 2002-09-20 | 2004-04-01 | Alpharma, Inc. | Sustained-release opioid formulations and methods of use |
WO2004092209A2 (en) | 2003-04-15 | 2004-10-28 | Intercell Ag | S. pneumoniae antigens |
GB0318688D0 (en) | 2003-08-08 | 2003-09-10 | Chiron Srl | Streptococcus pneumoniae knockout mutants |
AU2005319174A1 (en) | 2004-12-22 | 2006-06-29 | J. Craig Venter Institute, Inc. | Group B Streptococcus |
WO2006084466A2 (en) | 2005-02-11 | 2006-08-17 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides |
AU2007225238A1 (en) | 2006-03-10 | 2007-09-20 | Wyeth | Microarray for monitoring gene expression in multiple strains of Streptococcus pneumoniae |
PL2054431T3 (en) | 2006-06-09 | 2012-07-31 | Novartis Ag | Conformers of bacterial adhesins |
GB0700136D0 (en) | 2007-01-04 | 2007-02-14 | Glaxosmithkline Biolog Sa | Process for manufacturing vaccines |
WO2008119358A2 (en) | 2007-03-30 | 2008-10-09 | Ace Biosciences A/S | Surface-located streptococcus pneumoniae polypeptides for use in vaccine compositions |
CN101855362A (en) | 2007-05-18 | 2010-10-06 | 美国政府健康及人类服务部,疾病控制和预防中心 | Primers and probes for the detection of streptococcus pneumoniae |
US20110097360A1 (en) | 2007-05-25 | 2011-04-28 | Claudio Donati | Streptococcus pneumoniae pilus antigens |
US20100247547A1 (en) | 2007-05-29 | 2010-09-30 | Chen Dong | Modulation of the th-17 cell mediated immune responses |
GB0714963D0 (en) | 2007-08-01 | 2007-09-12 | Novartis Ag | Compositions comprising antigens |
WO2009033742A2 (en) | 2007-09-14 | 2009-03-19 | Katholieke Universiteit Leuven | Streptococcus pneumoniae vaccines |
US8466259B2 (en) | 2007-12-07 | 2013-06-18 | National Health Research Institutes | Adjuvants |
US7833776B2 (en) | 2007-12-12 | 2010-11-16 | National Health Research Institutes | Lipidating sequences and use thereof for producing lipidated proteins in E. coli |
EA023888B1 (en) | 2008-03-14 | 2016-07-29 | Санофи Пастер Байолоджикс, Ллс | Replication-defective flavivirus vaccines and vaccine vectors |
EP2300828B1 (en) | 2008-07-01 | 2018-09-05 | Genocea Biosciences Inc. | Antigen screening system |
EP2356225A1 (en) | 2008-12-03 | 2011-08-17 | Protea Vaccine Technologies Ltd. | GLUTAMYL tRNA SYNTHETASE (GtS) FRAGMENTS |
US8287880B2 (en) | 2009-06-02 | 2012-10-16 | National Health Research Institutes | Lipidated vaccine against dengue virus infection |
WO2010148496A1 (en) | 2009-06-22 | 2010-12-29 | National Health Research Institutes | Lipidated tumor- associated antigens and immunotherapeutic compositions |
WO2010150242A2 (en) | 2009-06-25 | 2010-12-29 | Protea Vaccine Technologies Ltd. | Immunogenic streptococcus pneumoniae peptides and peptide-multimers |
WO2011064781A1 (en) | 2009-11-30 | 2011-06-03 | Ben-Gurion University Of The Negev Research And Development Authority | S. pneumoniae adhesins |
WO2011067758A2 (en) | 2009-12-02 | 2011-06-09 | Protea Vaccine Technologies Ltd. | Immunogenic fragments and multimers from streptococcus pneumoniae proteins |
JP5065434B2 (en) | 2010-04-06 | 2012-10-31 | 株式会社日立製作所 | Management method and management apparatus |
WO2011128892A2 (en) | 2010-04-12 | 2011-10-20 | Protea Vaccine Technologies Ltd. | Modified forms of pneumococcal surface immunogenic protein b (psipb) |
WO2011141968A1 (en) | 2010-05-14 | 2011-11-17 | Hitachi, Ltd. | Storage apparatus and data retaining method for storage apparatus |
RU2623174C2 (en) | 2011-01-20 | 2017-06-22 | Дженоцея Байосайенсиз, Инк. | Vaccines and composition against streptococcus pneumoniae |
-
2012
- 2012-01-20 RU RU2013138563A patent/RU2623174C2/en not_active IP Right Cessation
- 2012-01-20 CA CA2861313A patent/CA2861313A1/en not_active Abandoned
- 2012-01-20 CN CN201280006067.5A patent/CN103501809B/en not_active Expired - Fee Related
- 2012-01-20 MY MYPI2013002729A patent/MY163871A/en unknown
- 2012-01-20 SG SG2013055496A patent/SG192060A1/en unknown
- 2012-01-20 EP EP12736908.0A patent/EP2665490B1/en active Active
- 2012-01-20 MX MX2013008358A patent/MX344120B/en active IP Right Grant
- 2012-01-20 US US13/355,468 patent/US9393294B2/en active Active
- 2012-01-20 AU AU2012207088A patent/AU2012207088A1/en not_active Abandoned
- 2012-01-20 JP JP2013550649A patent/JP6126993B2/en not_active Expired - Fee Related
- 2012-01-20 WO PCT/US2012/022127 patent/WO2012100233A1/en active Application Filing
- 2012-01-20 WO PCT/US2012/022128 patent/WO2012100234A1/en active Application Filing
- 2012-01-20 SG SG10201600435UA patent/SG10201600435UA/en unknown
- 2012-01-20 AU AU2012207089A patent/AU2012207089B2/en not_active Ceased
- 2012-01-20 BR BR112013018642-9A patent/BR112013018642A2/en not_active Application Discontinuation
- 2012-01-20 CN CN201610211251.3A patent/CN105833260A/en active Pending
- 2012-01-20 KR KR1020137021818A patent/KR20140017554A/en not_active Application Discontinuation
-
2013
- 2013-07-18 IL IL227554A patent/IL227554A/en active IP Right Grant
-
2016
- 2016-06-13 US US15/180,844 patent/US10188717B2/en not_active Expired - Fee Related
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002077021A2 (en) * | 2001-03-27 | 2002-10-03 | Chiron Srl. | Streptococcus pneumoniae proteins and nucleic acids |
WO2011008548A1 (en) * | 2009-06-29 | 2011-01-20 | Genocea Biosciences, Inc. | Vaccines and compositions against streptococcus pneumoniae |
Non-Patent Citations (4)
Title |
---|
KRISTIN L MOFFITT ET AL: "T17-Based Vaccine Design for Prevention ofColonization", CELL HOST & MICROBE, ELSEVIER, NL, vol. 9, no. 2, 17 February 2011 (2011-02-17), pages 158 - 165, XP028365196, ISSN: 1931-3128, [retrieved on 20110129], DOI: 10.1016/J.CHOM.2011.01.007 * |
See also references of WO2012100234A1 * |
YING-JIE LU ET AL: "Interleukin-17A Mediates Acquired Immunity to Pneumococcal Colonization", PLOS PATHOGENS, vol. 4, no. 9, 19 September 2008 (2008-09-19), pages e1000159, XP055189295, DOI: 10.1371/journal.ppat.1000159 * |
YUAN LI ET AL: "Distinct Effects on Diversifying Selection by Two Mechanisms of Immunity against Streptococcus pneumoniae", PLOS PATHOGENS, vol. 8, no. 11, 8 November 2012 (2012-11-08), pages e1002989, XP055189293, DOI: 10.1371/journal.ppat.1002989 * |
Also Published As
Publication number | Publication date |
---|---|
RU2013138563A (en) | 2015-02-27 |
WO2012100233A1 (en) | 2012-07-26 |
JP2014503002A (en) | 2014-02-06 |
AU2012207089A1 (en) | 2013-05-02 |
US9393294B2 (en) | 2016-07-19 |
IL227554A (en) | 2016-10-31 |
US20170157234A1 (en) | 2017-06-08 |
WO2012100234A1 (en) | 2012-07-26 |
CN103501809B (en) | 2018-08-10 |
AU2012207089B2 (en) | 2016-04-14 |
BR112013018642A2 (en) | 2019-04-30 |
SG192060A1 (en) | 2013-08-30 |
IL227554A0 (en) | 2013-09-30 |
US20120189649A1 (en) | 2012-07-26 |
US10188717B2 (en) | 2019-01-29 |
CN105833260A (en) | 2016-08-10 |
EP2665490A1 (en) | 2013-11-27 |
MY163871A (en) | 2017-10-31 |
CN103501809A (en) | 2014-01-08 |
JP6126993B2 (en) | 2017-05-10 |
KR20140017554A (en) | 2014-02-11 |
EP2665490B1 (en) | 2020-03-04 |
MX344120B (en) | 2016-12-06 |
MX2013008358A (en) | 2013-09-02 |
RU2623174C2 (en) | 2017-06-22 |
AU2012207088A1 (en) | 2013-05-02 |
NZ614460A (en) | 2015-08-28 |
CA2861313A1 (en) | 2012-07-26 |
SG10201600435UA (en) | 2016-02-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL257533B (en) | Yeast-muc1 immunotherapeutic compositions and uses thereof | |
SG10201600435UA (en) | Vaccines And Compositions Against Streptococcus Pneumoniae | |
SG10201403702SA (en) | Vaccines and compositions against streptococcus pneumoniae | |
HK1199694A1 (en) | Probiotic compositions and methods | |
ZA201408594B (en) | Xylitol-based anti-mucosal compositions and related methods and compositions | |
EP2763665A4 (en) | Antimicrobial compositions and methods employing same | |
HK1210714A1 (en) | Antibody formulations and uses thereof | |
EP2825196A4 (en) | Adjuvant and vaccine compositions | |
ZA201308537B (en) | Vaccine against streptococcus pneumoniae | |
HK1206970A1 (en) | Antigenic compositions and methods | |
GB201315350D0 (en) | Methods and compositions | |
ZA201304517B (en) | Composition for immunization against streptococcus pneumoniae | |
GB201315347D0 (en) | Methods and compositions | |
EP2668044A4 (en) | Compositions and their use | |
ZA201308892B (en) | Compositions and methods | |
EP2766357A4 (en) | Meso-biliverdin compositions and methods | |
GB201106357D0 (en) | Composition and uses thereof | |
EP2804627A4 (en) | Fused antigen vaccines and compositions against streptococcus pneumoniae | |
HK1200724A1 (en) | Chlamydia antigen compositions and uses thereof | |
GB201120470D0 (en) | Compositions and uses thereof | |
GB201116340D0 (en) | Compositions and methods | |
GB201107454D0 (en) | Compositions and uses | |
GB201101924D0 (en) | Compositions and uses | |
TWM388902U (en) | Dual-purpose pillow | |
IL205570A0 (en) | Multipurpose scribable article |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20130820 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
DAX | Request for extension of the european patent (deleted) | ||
RA4 | Supplementary search report drawn up and despatched (corrected) |
Effective date: 20150603 |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 39/09 20060101AFI20150528BHEP Ipc: A61K 38/00 20060101ALI20150528BHEP |
|
17Q | First examination report despatched |
Effective date: 20160816 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R079 Ref document number: 602012068232 Country of ref document: DE Free format text: PREVIOUS MAIN CLASS: A61K0039090000 Ipc: A61P0031040000 |
|
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61P 31/04 20060101AFI20190109BHEP |
|
INTG | Intention to grant announced |
Effective date: 20190206 |
|
GRAJ | Information related to disapproval of communication of intention to grant by the applicant or resumption of examination proceedings by the epo deleted |
Free format text: ORIGINAL CODE: EPIDOSDIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: EXAMINATION IS IN PROGRESS |
|
INTC | Intention to grant announced (deleted) | ||
GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: GRANT OF PATENT IS INTENDED |
|
INTG | Intention to grant announced |
Effective date: 20190816 |
|
GRAS | Grant fee paid |
Free format text: ORIGINAL CODE: EPIDOSNIGR3 |
|
GRAA | (expected) grant |
Free format text: ORIGINAL CODE: 0009210 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE PATENT HAS BEEN GRANTED |
|
AK | Designated contracting states |
Kind code of ref document: B1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
|
REG | Reference to a national code |
Ref country code: GB Ref legal event code: FG4D |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: EP |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: REF Ref document number: 1239699 Country of ref document: AT Kind code of ref document: T Effective date: 20200315 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R096 Ref document number: 602012068232 Country of ref document: DE |
|
REG | Reference to a national code |
Ref country code: IE Ref legal event code: FG4D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: RS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: NO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200604 Ref country code: FI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
REG | Reference to a national code |
Ref country code: NL Ref legal event code: MP Effective date: 20200304 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: LV Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: HR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: BG Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200604 Ref country code: GR Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200605 |
|
REG | Reference to a national code |
Ref country code: LT Ref legal event code: MG4D |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: NL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: EE Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: PT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200729 Ref country code: RO Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: LT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: SM Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: IS Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200704 Ref country code: SK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: CZ Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: ES Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
REG | Reference to a national code |
Ref country code: AT Ref legal event code: MK05 Ref document number: 1239699 Country of ref document: AT Kind code of ref document: T Effective date: 20200304 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R097 Ref document number: 602012068232 Country of ref document: DE |
|
PLBE | No opposition filed within time limit |
Free format text: ORIGINAL CODE: 0009261 |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: NO OPPOSITION FILED WITHIN TIME LIMIT |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: AT Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: DK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
26N | No opposition filed |
Effective date: 20201207 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: SI Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 Ref country code: PL Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MC Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
REG | Reference to a national code |
Ref country code: CH Ref legal event code: PL |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LU Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210120 |
|
REG | Reference to a national code |
Ref country code: BE Ref legal event code: MM Effective date: 20210131 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: LI Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210131 Ref country code: CH Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210131 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: IE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210120 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: GB Payment date: 20220127 Year of fee payment: 11 Ref country code: DE Payment date: 20220127 Year of fee payment: 11 |
|
PGFP | Annual fee paid to national office [announced via postgrant information from national office to epo] |
Ref country code: FR Payment date: 20220125 Year of fee payment: 11 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: BE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20210131 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: HU Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT; INVALID AB INITIO Effective date: 20120120 Ref country code: CY Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |
|
REG | Reference to a national code |
Ref country code: DE Ref legal event code: R119 Ref document number: 602012068232 Country of ref document: DE |
|
GBPC | Gb: european patent ceased through non-payment of renewal fee |
Effective date: 20230120 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: GB Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230120 Ref country code: DE Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230801 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: FR Free format text: LAPSE BECAUSE OF NON-PAYMENT OF DUE FEES Effective date: 20230131 |
|
PG25 | Lapsed in a contracting state [announced via postgrant information from national office to epo] |
Ref country code: MK Free format text: LAPSE BECAUSE OF FAILURE TO SUBMIT A TRANSLATION OF THE DESCRIPTION OR TO PAY THE FEE WITHIN THE PRESCRIBED TIME-LIMIT Effective date: 20200304 |