BR112013015003A2 - método para obter um composto - Google Patents

método para obter um composto

Info

Publication number
BR112013015003A2
BR112013015003A2 BR112013015003A BR112013015003A BR112013015003A2 BR 112013015003 A2 BR112013015003 A2 BR 112013015003A2 BR 112013015003 A BR112013015003 A BR 112013015003A BR 112013015003 A BR112013015003 A BR 112013015003A BR 112013015003 A2 BR112013015003 A2 BR 112013015003A2
Authority
BR
Brazil
Prior art keywords
compound
Prior art date
Application number
BR112013015003A
Other languages
English (en)
Other versions
BR112013015003B1 (pt
Inventor
Anne Nilsen
Sondre Nilsen
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BR112013015003A2 publication Critical patent/BR112013015003A2/pt
Publication of BR112013015003B1 publication Critical patent/BR112013015003B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C07C227/20Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001Acyclic or carbocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/24Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/26Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids
    • C07C303/28Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of esters of sulfonic acids by reaction of hydroxy compounds with sulfonic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/72Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C309/73Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Indole Compounds (AREA)
BR112013015003-3A 2010-12-20 2011-12-19 Método e método radiossintético para obter derivados de aminoácidos protegidos BR112013015003B1 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201061424695P 2010-12-20 2010-12-20
GB1021530.9 2010-12-20
US61/424695 2010-12-20
GBGB1021530.9A GB201021530D0 (en) 2010-12-20 2010-12-20 Purification of precursor compound by crystallisation
PCT/EP2011/073247 WO2012084831A1 (en) 2010-12-20 2011-12-19 Purification of precursor compound by crystallisation

Publications (2)

Publication Number Publication Date
BR112013015003A2 true BR112013015003A2 (pt) 2016-08-09
BR112013015003B1 BR112013015003B1 (pt) 2019-07-02

Family

ID=43598631

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013015003-3A BR112013015003B1 (pt) 2010-12-20 2011-12-19 Método e método radiossintético para obter derivados de aminoácidos protegidos

Country Status (12)

Country Link
EP (1) EP2655321B1 (pt)
JP (1) JP6240507B2 (pt)
KR (1) KR101925650B1 (pt)
CN (2) CN103261153A (pt)
AU (1) AU2011347530B2 (pt)
BR (1) BR112013015003B1 (pt)
CA (1) CA2821951C (pt)
DK (1) DK2655321T3 (pt)
ES (1) ES2621940T3 (pt)
GB (1) GB201021530D0 (pt)
RU (1) RU2586881C2 (pt)
WO (1) WO2012084831A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201214220D0 (en) 2012-08-09 2012-09-19 Ge Healthcare Ltd Radiosynthesis

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559766B1 (fr) * 1984-02-16 1986-05-16 Poudres & Explosifs Ste Nale Procede de preparation de derives de l'acide carbamique
US5808146A (en) * 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
JP3705657B2 (ja) * 1996-09-05 2005-10-12 信越化学工業株式会社 N,n−ジアルキルカルバミン酸2−ニトロベンジルエステル類の製造方法
US6824760B2 (en) * 2001-06-04 2004-11-30 The University Of Texas System Imaging agents, precursors thereof and methods of manufacture
GB0229695D0 (en) * 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
EP1893246A4 (en) * 2005-06-23 2009-05-06 Univ Emory STEREOSELECTIVE SYNTHESIS OF AMINO ACID ANALOGUE FOR TUMOR IMAGING
WO2007063824A1 (ja) * 2005-11-29 2007-06-07 Nihon Medi-Physics Co., Ltd. 放射性ハロゲン標識有機化合物の前駆体化合物
JP4550141B2 (ja) * 2006-05-11 2010-09-22 日本メジフィジックス株式会社 放射性フッ素標識有機化合物の製造方法
RU2466984C2 (ru) * 2006-12-27 2012-11-20 Нихон Меди-Физикс Ко., Лтд. Процесс получения соединений-предшественников для радиоактивных галогенпомеченных соединений
DK2230229T3 (en) * 2007-12-19 2017-01-23 Nihon Mediphysics Co Ltd Process for the preparation of radioactive-fluoro-labeled organic compound
EP2325167A4 (en) * 2008-07-28 2012-03-07 Ube Industries METHOD FOR PRODUCING A CARBAMATE COMPOUND

Also Published As

Publication number Publication date
CA2821951A1 (en) 2012-06-28
GB201021530D0 (en) 2011-02-02
WO2012084831A1 (en) 2012-06-28
ES2621940T3 (es) 2017-07-05
AU2011347530A1 (en) 2013-07-25
CA2821951C (en) 2019-11-26
DK2655321T3 (en) 2017-04-18
CN103261153A (zh) 2013-08-21
JP6240507B2 (ja) 2017-11-29
KR101925650B1 (ko) 2018-12-05
BR112013015003B1 (pt) 2019-07-02
KR20140003490A (ko) 2014-01-09
RU2586881C2 (ru) 2016-06-10
CN107266339A (zh) 2017-10-20
EP2655321B1 (en) 2017-02-15
RU2013127011A (ru) 2015-01-27
EP2655321A1 (en) 2013-10-30
AU2011347530B2 (en) 2016-09-15
JP2014509303A (ja) 2014-04-17

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/12/2011, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/12/2011, OBSERVADAS AS CONDICOES LEGAIS