BR112013002299A2 - método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo - Google Patents
método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimoInfo
- Publication number
- BR112013002299A2 BR112013002299A2 BR112013002299A BR112013002299A BR112013002299A2 BR 112013002299 A2 BR112013002299 A2 BR 112013002299A2 BR 112013002299 A BR112013002299 A BR 112013002299A BR 112013002299 A BR112013002299 A BR 112013002299A BR 112013002299 A2 BR112013002299 A2 BR 112013002299A2
- Authority
- BR
- Brazil
- Prior art keywords
- sequencing
- capturing
- determining
- nucleic acid
- dna fragment
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 239000012634 fragment Substances 0.000 title 1
- 230000011987 methylation Effects 0.000 title 1
- 238000007069 methylation reaction Methods 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 238000012163 sequencing technique Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40235010P | 2010-08-27 | 2010-08-27 | |
| PCT/US2011/049151 WO2012027572A2 (en) | 2010-08-27 | 2011-08-25 | Methods for nucleic acid capture and sequencing |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112013002299A2 true BR112013002299A2 (pt) | 2016-05-24 |
Family
ID=44545975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013002299A BR112013002299A2 (pt) | 2010-08-27 | 2011-08-25 | método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20130324419A1 (https=) |
| EP (1) | EP2609214A2 (https=) |
| JP (1) | JP2013535986A (https=) |
| KR (1) | KR20130101031A (https=) |
| CN (1) | CN103080338A (https=) |
| BR (1) | BR112013002299A2 (https=) |
| CA (1) | CA2803693A1 (https=) |
| MX (1) | MX2013001799A (https=) |
| RU (1) | RU2013113407A (https=) |
| WO (1) | WO2012027572A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9074251B2 (en) | 2011-02-10 | 2015-07-07 | Illumina, Inc. | Linking sequence reads using paired code tags |
| CN103443338B (zh) | 2011-02-02 | 2017-09-22 | 华盛顿大学商业化中心 | 大规模平行邻接作图 |
| NO2694769T3 (https=) | 2012-03-06 | 2018-03-03 | ||
| CA2876505A1 (en) * | 2012-07-17 | 2014-01-23 | Counsyl, Inc. | System and methods for detecting genetic variation |
| US9683230B2 (en) | 2013-01-09 | 2017-06-20 | Illumina Cambridge Limited | Sample preparation on a solid support |
| DK2970951T3 (da) | 2013-03-13 | 2019-05-13 | Illumina Inc | Fremgangsmåder til nukleinsyresekventering |
| EP3957750B1 (en) | 2013-12-20 | 2025-01-29 | Illumina, Inc. | Preserving genomic connectivity information in fragmented genomic dna samples |
| RU2736728C2 (ru) | 2014-10-17 | 2020-11-19 | Иллумина Кембридж Лимитед | Транспозиция с сохранением сцепления генов |
| EP3207134B1 (en) * | 2014-10-17 | 2019-07-03 | Illumina Cambridge Limited | Contiguity preserving transposition |
| CA2971589C (en) | 2014-12-18 | 2021-09-28 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10395759B2 (en) * | 2015-05-18 | 2019-08-27 | Regeneron Pharmaceuticals, Inc. | Methods and systems for copy number variant detection |
| WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
| EP3650553B1 (en) * | 2018-11-07 | 2023-07-12 | Siemens Healthcare GmbH | Method for detection of specific nucleic acids |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO165894C (no) * | 1988-05-24 | 1991-04-24 | Gunnar Paulsen | Analysemetode for gener. |
| US6982146B1 (en) * | 1999-08-30 | 2006-01-03 | The United States Of America As Represented By The Department Of Health And Human Services | High speed parallel molecular nucleic acid sequencing |
| WO2008115185A2 (en) | 2006-04-24 | 2008-09-25 | Nimblegen Systems, Inc. | Use of microarrays for genomic representation selection |
| WO2008096146A1 (en) * | 2007-02-07 | 2008-08-14 | Solexa Limited | Preparation of templates for methylation analysis |
| US20100035268A1 (en) * | 2007-02-21 | 2010-02-11 | Joseph Beechem | Materials and methods for single molecule nucleic acid sequencing |
| CN101802223A (zh) * | 2007-08-15 | 2010-08-11 | 香港大学 | 用于高通量亚硫酸氢盐dna-测序的方法和组合物及其用途 |
| US20110281740A1 (en) | 2008-06-30 | 2011-11-17 | Joseph Beechem | Methods for Real Time Single Molecule Sequencing |
| US8795961B2 (en) * | 2008-09-05 | 2014-08-05 | Pacific Biosciences Of California, Inc. | Preparations, compositions, and methods for nucleic acid sequencing |
| US20120149593A1 (en) | 2009-01-23 | 2012-06-14 | Hicks James B | Methods and arrays for profiling dna methylation |
-
2011
- 2011-08-25 CA CA2803693A patent/CA2803693A1/en not_active Abandoned
- 2011-08-25 US US13/819,657 patent/US20130324419A1/en not_active Abandoned
- 2011-08-25 BR BR112013002299A patent/BR112013002299A2/pt not_active IP Right Cessation
- 2011-08-25 WO PCT/US2011/049151 patent/WO2012027572A2/en not_active Ceased
- 2011-08-25 KR KR1020137007586A patent/KR20130101031A/ko not_active Withdrawn
- 2011-08-25 CN CN2011800416596A patent/CN103080338A/zh active Pending
- 2011-08-25 JP JP2013526153A patent/JP2013535986A/ja active Pending
- 2011-08-25 RU RU2013113407/10A patent/RU2013113407A/ru not_active Application Discontinuation
- 2011-08-25 EP EP11752056.9A patent/EP2609214A2/en not_active Withdrawn
- 2011-08-25 MX MX2013001799A patent/MX2013001799A/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20130324419A1 (en) | 2013-12-05 |
| JP2013535986A (ja) | 2013-09-19 |
| EP2609214A2 (en) | 2013-07-03 |
| MX2013001799A (es) | 2013-05-20 |
| WO2012027572A2 (en) | 2012-03-01 |
| CA2803693A1 (en) | 2012-03-01 |
| KR20130101031A (ko) | 2013-09-12 |
| WO2012027572A3 (en) | 2012-06-07 |
| RU2013113407A (ru) | 2014-10-10 |
| CN103080338A (zh) | 2013-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112013002299A2 (pt) | método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo | |
| EP2414547A4 (en) | MULTIPLE PRIMER AMPLIFICATION METHOD FOR TARGET NUCLEIC ACID BAR CODING | |
| IL233773B (en) | Methods for identifying a target sequence of a nucleic acid from DNA or a mixture of nucleic acids and a kit for performing these methods | |
| GB2499340B (en) | Methods for sequencing nucleic acids | |
| IL251515A0 (en) | Bambam: Parallel Comparative Analysis of Serial Data at High Transfer Rate | |
| SG11201401628WA (en) | Compositions and methods for directional nucleic acid amplification and sequencing | |
| SG2014014617A (en) | Nucleic acid analysis | |
| EP2201021A4 (en) | METHOD OF ALTERNATING NUCLEIC ACID SEQUENCING | |
| EP3365445A4 (en) | METHOD OF GENOMEMBLING, HAPLOTYP PHASING AND TARGET INDEPENDENT NUCLEIC ACID DETECTION | |
| EP2791160A4 (en) | NUCLEOSIDE, NUCLEOTIDE, AND MODIFIED NUCLEIC ACID COMPOSITIONS | |
| SI3623481T1 (sl) | Sestavki za sekvenciranje nukleinske kisline | |
| IL232512A0 (en) | Parallel comparative analysis of high-throughput sequencing data | |
| EP2673380A4 (en) | ANALYSIS OF NUCLEIC ACIDS | |
| EP2431466A4 (en) | EINSTRÄNGIG NUCLEIC ACID MOLECULE FOR GENE EXPRESSION CONTROL | |
| DK2129797T3 (da) | Nukleinsyrepåvisning | |
| DK2572004T3 (da) | Detection of target nucleic acid sequences by pto cleavage and extension assay | |
| EP2872523A4 (en) | NUCLEIC ACID PURIFICATION OF A MICROORGANISM FROM HOST SAMPLES | |
| EP2480689A4 (en) | DETECTION OF TARGET NUCLEIC ACID SEQUENCES USING CYCLIC EXONUCLEOLYTIC REACTIONS | |
| EP2303458A4 (en) | Nucleic Acid Extraction DEVICE | |
| EP2576836A4 (en) | COMPOSITIONS AND METHODS FOR THE SEQUENCING OF NUCLEIC ACIDS | |
| SG11201400635UA (en) | Method for detecting target nucleic acid | |
| IL223257A0 (en) | Method of dna sequencing by hybridisation | |
| BRPI1006411A2 (pt) | seleção genômica e sequenciamento utilizando microcarreadores codificados, processo para determinar a sequência de uma molécula de ácido nucleico alvo, e, dispositivo para determinar a sequência de uma amostra de ácido nucleico | |
| IL223256A0 (en) | Method of dna sequencing by polymerisation | |
| IL229132A0 (en) | Discovery of target nucleic acid sequences by po cutting and hybridization |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |