BR112013002299A2 - método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo - Google Patents

método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo

Info

Publication number
BR112013002299A2
BR112013002299A2 BR112013002299A BR112013002299A BR112013002299A2 BR 112013002299 A2 BR112013002299 A2 BR 112013002299A2 BR 112013002299 A BR112013002299 A BR 112013002299A BR 112013002299 A BR112013002299 A BR 112013002299A BR 112013002299 A2 BR112013002299 A2 BR 112013002299A2
Authority
BR
Brazil
Prior art keywords
sequencing
capturing
determining
nucleic acid
dna fragment
Prior art date
Application number
BR112013002299A
Other languages
English (en)
Inventor
Somasekar Seshagiri
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of BR112013002299A2 publication Critical patent/BR112013002299A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1072—Differential gene expression library synthesis, e.g. subtracted libraries, differential screening
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112013002299A 2010-08-27 2011-08-25 método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo BR112013002299A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40235010P 2010-08-27 2010-08-27
PCT/US2011/049151 WO2012027572A2 (en) 2010-08-27 2011-08-25 Methods for nucleic acid capture and sequencing

Publications (1)

Publication Number Publication Date
BR112013002299A2 true BR112013002299A2 (pt) 2016-05-24

Family

ID=44545975

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013002299A BR112013002299A2 (pt) 2010-08-27 2011-08-25 método de captura e sequenciamento de uma molécula alvo de ácido nucleíco e método de determinação do estado de metilação de um fragmento de dna genônimo

Country Status (10)

Country Link
US (1) US20130324419A1 (pt)
EP (1) EP2609214A2 (pt)
JP (1) JP2013535986A (pt)
KR (1) KR20130101031A (pt)
CN (1) CN103080338A (pt)
BR (1) BR112013002299A2 (pt)
CA (1) CA2803693A1 (pt)
MX (1) MX2013001799A (pt)
RU (1) RU2013113407A (pt)
WO (1) WO2012027572A2 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012106546A2 (en) 2011-02-02 2012-08-09 University Of Washington Through Its Center For Commercialization Massively parallel continguity mapping
NO2694769T3 (pt) * 2012-03-06 2018-03-03
CN104812947B (zh) * 2012-07-17 2018-04-27 考希尔股份有限公司 检测遗传变异的系统和方法
US9683230B2 (en) 2013-01-09 2017-06-20 Illumina Cambridge Limited Sample preparation on a solid support
CA3094792A1 (en) 2013-03-13 2014-09-18 Illumina, Inc. Methods and compositions for nucleic acid sequencing
CN106414765A (zh) 2013-12-20 2017-02-15 Illumina公司 在片段化的基因组dna样品中保留基因组连接信息
BR112017007912A2 (pt) 2014-10-17 2018-01-23 Illumina Cambridge Limited transposon de preservação de contiguidade
CN114045282A (zh) * 2014-10-17 2022-02-15 伊卢米纳剑桥有限公司 接近性保留性转座
US9859394B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
WO2016100049A1 (en) 2014-12-18 2016-06-23 Edico Genome Corporation Chemically-sensitive field effect transistor
US10006910B2 (en) 2014-12-18 2018-06-26 Agilome, Inc. Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same
US9618474B2 (en) 2014-12-18 2017-04-11 Edico Genome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US10020300B2 (en) 2014-12-18 2018-07-10 Agilome, Inc. Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids
US9857328B2 (en) 2014-12-18 2018-01-02 Agilome, Inc. Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same
US10395759B2 (en) * 2015-05-18 2019-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for copy number variant detection
EP3459115A4 (en) 2016-05-16 2020-04-08 Agilome, Inc. GRAPHEN-FET DEVICES, SYSTEMS AND METHODS FOR USE THEREOF FOR SEQUENCING NUCLEIC ACIDS
EP3650553B1 (en) * 2018-11-07 2023-07-12 Siemens Healthcare GmbH Method for detection of specific nucleic acids

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO165894C (no) * 1988-05-24 1991-04-24 Gunnar Paulsen Analysemetode for gener.
US6982146B1 (en) * 1999-08-30 2006-01-03 The United States Of America As Represented By The Department Of Health And Human Services High speed parallel molecular nucleic acid sequencing
WO2008115185A2 (en) 2006-04-24 2008-09-25 Nimblegen Systems, Inc. Use of microarrays for genomic representation selection
WO2008096146A1 (en) * 2007-02-07 2008-08-14 Solexa Limited Preparation of templates for methylation analysis
EP2126072A4 (en) * 2007-02-21 2011-07-13 Life Technologies Corp MATERIALS AND METHOD FOR THE INDIVIDUAL MOLECULE SEQUENCING OF NUCLEIC ACIDS
WO2009024019A1 (en) * 2007-08-15 2009-02-26 The University Of Hong Kong Methods and compositions for high-throughput bisulphite dna-sequencing and utilities
US20110281740A1 (en) 2008-06-30 2011-11-17 Joseph Beechem Methods for Real Time Single Molecule Sequencing
WO2010027497A2 (en) * 2008-09-05 2010-03-11 Pacific Biosciences Of California, Inc Preparations, compositions, and methods for nucleic acid sequencing
WO2010085343A1 (en) 2009-01-23 2010-07-29 Cold Spring Harbor Laboratory Methods and arrays for profiling dna methylation

Also Published As

Publication number Publication date
CA2803693A1 (en) 2012-03-01
US20130324419A1 (en) 2013-12-05
WO2012027572A2 (en) 2012-03-01
CN103080338A (zh) 2013-05-01
WO2012027572A3 (en) 2012-06-07
MX2013001799A (es) 2013-05-20
RU2013113407A (ru) 2014-10-10
EP2609214A2 (en) 2013-07-03
KR20130101031A (ko) 2013-09-12
JP2013535986A (ja) 2013-09-19

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]