BR112012032406A2 - marcadores para o prognóstico e avaliação de risco de hipertensão induzida pela gravidez e pré-eclâmpsia - Google Patents
marcadores para o prognóstico e avaliação de risco de hipertensão induzida pela gravidez e pré-eclâmpsiaInfo
- Publication number
- BR112012032406A2 BR112012032406A2 BR112012032406A BR112012032406A BR112012032406A2 BR 112012032406 A2 BR112012032406 A2 BR 112012032406A2 BR 112012032406 A BR112012032406 A BR 112012032406A BR 112012032406 A BR112012032406 A BR 112012032406A BR 112012032406 A2 BR112012032406 A2 BR 112012032406A2
- Authority
- BR
- Brazil
- Prior art keywords
- preeclampsia
- prognosis
- pregnancy
- risk assessment
- markers
- Prior art date
Links
- 206010070538 Gestational hypertension Diseases 0.000 title abstract 3
- 201000005624 HELLP Syndrome Diseases 0.000 title abstract 3
- 208000005347 Pregnancy-Induced Hypertension Diseases 0.000 title abstract 3
- 201000011461 pre-eclampsia Diseases 0.000 title abstract 3
- 208000036335 preeclampsia/eclampsia 1 Diseases 0.000 title abstract 3
- 238000004393 prognosis Methods 0.000 title abstract 3
- 238000012502 risk assessment Methods 0.000 title abstract 3
- 239000003550 marker Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/02—Measuring pulse or heart rate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/32—Cardiovascular disorders
- G01N2800/321—Arterial hypertension
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Cardiology (AREA)
- Medical Informatics (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
Abstract
marcadores para o prognóstico e avaliação de risco de hipertensão induzida pela gravidez e pré-eclâmpsia. a presente invenção refere-se ao prognóstico e avaliação de risco em mulheres grávidas de desenvolver hipertensão induzida pela gravidez e/ou pré-eclâmpsia pela determinação de níveis de marcadores.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10290332 | 2010-06-18 | ||
PCT/EP2011/003018 WO2011157445A1 (en) | 2010-06-18 | 2011-06-17 | Markers for the prognosis and risk assessment of pregnancy-induced hypertension and preeclampsia |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112012032406A2 true BR112012032406A2 (pt) | 2016-10-25 |
Family
ID=42668216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012032406A BR112012032406A2 (pt) | 2010-06-18 | 2011-06-17 | marcadores para o prognóstico e avaliação de risco de hipertensão induzida pela gravidez e pré-eclâmpsia |
Country Status (7)
Country | Link |
---|---|
US (1) | US20130177901A1 (pt) |
EP (1) | EP2583106A1 (pt) |
JP (1) | JP5684904B2 (pt) |
CN (1) | CN103109192A (pt) |
BR (1) | BR112012032406A2 (pt) |
RU (1) | RU2013102112A (pt) |
WO (1) | WO2011157445A1 (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA3086149A1 (en) | 2006-04-04 | 2007-10-11 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
US7838250B1 (en) | 2006-04-04 | 2010-11-23 | Singulex, Inc. | Highly sensitive system and methods for analysis of troponin |
AU2010259022B2 (en) | 2009-06-08 | 2016-05-12 | Singulex, Inc. | Highly sensitive biomarker panels |
RU2480762C1 (ru) * | 2012-03-19 | 2013-04-27 | Федеральное государственное бюджетное учреждение "Уральский научно-исследовательский институт охраны материнства и младенчества" Министерства здравоохранения и социального развития Российской Федерации (ФГБУ "НИИ ОММ" Минздравсоцразвития России) | Способ прогноза формирования эссенциальной артериальной гипертензии у женщин с гипертензивными нарушениями при беременности |
SG10201700872TA (en) | 2012-08-13 | 2017-04-27 | Otago Innovation Ltd | NT-proCNP AS A BIOMARKER OF VASCULAR DISORDERS AND PREGNANCY COMPLICATION |
US20150330989A1 (en) * | 2012-11-15 | 2015-11-19 | The Brigham And Women's Hospital, Inc. | Method and system for diagnosing and treating preeclampsia |
US20150377876A1 (en) * | 2013-02-08 | 2015-12-31 | University Of Iowa Research Foundation | Diagnostic tools to predict onset of preeclampsia |
US20140273025A1 (en) * | 2013-03-15 | 2014-09-18 | Wallac Oy | System and method for determining risk of pre-eclampsia based on biochemical marker analysis |
US10598674B2 (en) * | 2013-03-20 | 2020-03-24 | Sphingotec Gmbh | Adrenomedullin to guide therapy of blood pressure decline |
RU2545760C2 (ru) * | 2013-05-31 | 2015-04-10 | Закрытое акционерное общество "Протеинсинтез" | Способ прогнозирования преэклампсии у беременных с плацентарной недостаточностью |
CN103513042A (zh) * | 2013-09-23 | 2014-01-15 | 中国科学院动物研究所 | 用于预测或早期诊断妊娠高血压疾病的试剂盒 |
CN103760342B (zh) * | 2014-01-28 | 2016-01-27 | 成都创宜生物科技有限公司 | 检测妊娠子痫前期的免疫层析试纸 |
RU2565405C1 (ru) * | 2014-05-07 | 2015-10-20 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | СПОСОБ ПРОГНОЗИРОВАНИЯ УРОВНЯ АРТЕРИАЛЬНОГО ДАВЛЕНИЯ У ЖЕНЩИН НА СРОКЕ РОДОРАЗРЕШЕНИЯ С ИСПОЛЬЗОВАНИЕМ ГЕНЕТИЧЕСКОГО ПОЛИМОРФИЗМА 4a/4b eNOS |
RU2558465C1 (ru) * | 2014-07-15 | 2015-08-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования Читинская государственная медицинская академия Министерства здравоохранения РФ | Способ доклинической диагностики преэклампсии |
WO2016042202A1 (en) | 2014-09-17 | 2016-03-24 | Wallac Oy | Method for determining the risk of preterm birth |
US20180114600A1 (en) * | 2015-03-23 | 2018-04-26 | Adelaide Research & Innovation Pty Ltd | Methods and systems for determining risk of a pregnancy complication occurring |
JP2019519795A (ja) * | 2016-04-13 | 2019-07-11 | アボット・ラボラトリーズAbbott Laboratories | 心血管疾患の同定及びリスク評価のための妊娠中の心臓トロポニンi検出 |
US20190128895A1 (en) * | 2016-04-20 | 2019-05-02 | Ldx Prognostics Limited Co. | Methods and compositions for prognosing preterm birth |
CN109196362A (zh) * | 2016-05-17 | 2019-01-11 | 苏州爱尔迪思生物科技有限公司 | 用于提供子痫前期评估的方法和组合物 |
CN109891239B (zh) * | 2016-10-24 | 2022-04-05 | 苏州爱尔迪思生物科技有限公司 | 用于提供子痫前期评估和预测早产的方法和试剂盒 |
GR20170100034A (el) * | 2017-01-27 | 2018-10-22 | Αθανασιος Κωνσταντινου Αναγνωστοπουλος | Η πρωτεϊνη c9jv37 ως δεικτης για την προγνωση και διαγνωση της προεκλαμψιας κατα την διαρκεια της κυησης |
US20200124612A1 (en) * | 2017-04-11 | 2020-04-23 | University Of Iowa Research Foundation | Detection of predictors of preeclampsia |
RU2691114C1 (ru) * | 2018-03-20 | 2019-06-11 | федеральное государственное бюджетное образовательное учреждение высшего образования "Ростовский государственный медицинский университет" Министерства здравоохранения Российской Федерации | Способ прогнозирования развития преэклампсии в поздние сроки беременности |
CN108776226B (zh) * | 2018-04-08 | 2021-03-19 | 邓成 | 晚发型子痫前期快速筛查用试纸和试剂盒 |
CN108614118B (zh) * | 2018-04-17 | 2021-08-27 | 广州市妇女儿童医疗中心(广州市妇幼保健院、广州市儿童医院、广州市妇婴医院、广州市妇幼保健计划生育服务中心) | 妊娠期高血压疾病相关标志物组合物及其应用 |
GB201910133D0 (en) * | 2019-07-15 | 2019-08-28 | Univ Tartu | Method of prognosing and diagnosing preeclampsia |
CN110387414B (zh) * | 2019-07-19 | 2022-09-30 | 广州市达瑞生物技术股份有限公司 | 一种利用外周血游离dna预测妊娠期糖尿病的模型 |
RU2741730C1 (ru) * | 2020-10-12 | 2021-01-28 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный медицинский университет имени академика Е.А. Вагнера" Министерства здравоохранения Российской Федерации | Способ прогнозирования риска развития тяжелых осложнений преэклампсии |
CN112816702A (zh) * | 2020-12-29 | 2021-05-18 | 苏州百志生物科技有限公司 | 一种检测人体液中可溶性内皮因子含量的试剂盒 |
RU2753463C1 (ru) * | 2021-02-28 | 2021-08-16 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) (ФГАОУ ВО Первый МГМУ им. И.М. Сеченова Минздрава России (Се | Способ прогнозирования тяжести течения ранней преэклампсии |
WO2022234111A1 (en) * | 2021-05-07 | 2022-11-10 | Sphingotec Gmbh | Mature adrenomedullin for therapy stratification of corticosteroids in critically ill patients |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0845036B1 (en) * | 1995-08-18 | 1999-06-02 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Functional role of adrenomedullin (am) and the gene-related product (pamp) in human pathology and physiology |
CN101245376A (zh) * | 2003-01-17 | 2008-08-20 | 香港中文大学 | 作为妊娠相关病症的诊断标志物的循环mRNA |
EP1619505B1 (en) * | 2004-07-22 | 2008-04-16 | BRAHMS Aktiengesellschaft | Method for the diagnosis of critically ill patients |
DE102004051847B4 (de) * | 2004-10-25 | 2008-09-18 | Dade Behring Marburg Gmbh | Verhältnis von PIGF und Flt-1 als prognostischer Parameter bei kardio-vaskulären Erkrankungen |
US20080071151A1 (en) * | 2006-06-30 | 2008-03-20 | Sogin David C | Method and Apparatus for Diagnosing Pre-eclampsia |
CN101643785B (zh) * | 2009-06-18 | 2011-12-21 | 中国人民解放军第二军医大学 | 用于妊娠高血压综合症检测的hsa-mir-210试剂盒及检测方法 |
-
2011
- 2011-06-17 BR BR112012032406A patent/BR112012032406A2/pt not_active IP Right Cessation
- 2011-06-17 WO PCT/EP2011/003018 patent/WO2011157445A1/en active Application Filing
- 2011-06-17 RU RU2013102112/15A patent/RU2013102112A/ru unknown
- 2011-06-17 JP JP2013514598A patent/JP5684904B2/ja not_active Expired - Fee Related
- 2011-06-17 US US13/704,654 patent/US20130177901A1/en not_active Abandoned
- 2011-06-17 EP EP11729558.4A patent/EP2583106A1/en not_active Withdrawn
- 2011-06-17 CN CN2011800301041A patent/CN103109192A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
RU2013102112A (ru) | 2014-07-27 |
JP5684904B2 (ja) | 2015-03-18 |
WO2011157445A1 (en) | 2011-12-22 |
EP2583106A1 (en) | 2013-04-24 |
JP2013533965A (ja) | 2013-08-29 |
CN103109192A (zh) | 2013-05-15 |
US20130177901A1 (en) | 2013-07-11 |
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Legal Events
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |