BR112012014996A8 - método diagnóstico baseado em rearranjo somaticamente adquirido - Google Patents

método diagnóstico baseado em rearranjo somaticamente adquirido Download PDF

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Publication number
BR112012014996A8
BR112012014996A8 BR112012014996A BR112012014996A BR112012014996A8 BR 112012014996 A8 BR112012014996 A8 BR 112012014996A8 BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A8 BR112012014996 A8 BR 112012014996A8
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BR
Brazil
Prior art keywords
method based
diagnostic method
somatically acquired
rearrangement
acquired rearrangement
Prior art date
Application number
BR112012014996A
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English (en)
Other versions
BR112012014996A2 (pt
Inventor
John Campbell Peter
Original Assignee
Genome Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Genome Res Ltd filed Critical Genome Res Ltd
Publication of BR112012014996A2 publication Critical patent/BR112012014996A2/pt
Publication of BR112012014996A8 publication Critical patent/BR112012014996A8/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BR112012014996A 2009-12-17 2010-12-16 método diagnóstico baseado em rearranjo somaticamente adquirido BR112012014996A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0922006.2A GB0922006D0 (en) 2009-12-17 2009-12-17 Diagnostic
PCT/GB2010/052110 WO2011073665A1 (en) 2009-12-17 2010-12-16 Diagnostic methods based on somatically acquired rearrangement

Publications (2)

Publication Number Publication Date
BR112012014996A2 BR112012014996A2 (pt) 2017-01-31
BR112012014996A8 true BR112012014996A8 (pt) 2018-04-03

Family

ID=41717068

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014996A BR112012014996A8 (pt) 2009-12-17 2010-12-16 método diagnóstico baseado em rearranjo somaticamente adquirido

Country Status (11)

Country Link
US (1) US20130122010A1 (pt)
EP (1) EP2513330B1 (pt)
JP (1) JP5963679B2 (pt)
CN (1) CN102939389B (pt)
BR (1) BR112012014996A8 (pt)
CA (1) CA2784613C (pt)
DK (1) DK2513330T3 (pt)
ES (1) ES2627961T3 (pt)
GB (1) GB0922006D0 (pt)
IN (1) IN2012DN06280A (pt)
WO (1) WO2011073665A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US8431123B2 (en) 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
US8710012B2 (en) 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
EP1880733A4 (en) 2005-04-25 2009-08-12 Genkin Dmitry Dmitrievich METHOD FOR EXTENDING THE LIFE OF A HUMAN AND ANIMALS
EP2095825B8 (en) 2006-11-28 2012-03-28 CLS Therapeutics Limited Method for treating human diseases associated with an increased deoxyribonucleic acid content in extracellular spaces of tissues and a medicinal preparation for carrying out said method
EP2536854B1 (en) * 2010-02-18 2017-07-19 The Johns Hopkins University Personalized tumor biomarkers
US11261494B2 (en) 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
EP3052651B1 (en) 2013-10-01 2019-11-27 Life Technologies Corporation Systems and methods for detecting structural variants
US10614910B2 (en) * 2014-05-30 2020-04-07 Nantomics, Llc Systems and methods for comprehensive analysis of molecular profiles across multiple tumor and germline exomes
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
DK3256605T3 (da) 2015-02-10 2022-03-14 Univ Hong Kong Chinese Påvisning af mutationer til cancerscreening og føtal analyse
JP6745873B2 (ja) 2015-05-22 2020-08-26 ドミトリエヴィッチ ゲンキン,ドミトリー 神経変性における治療標的としての細胞外dna
MY197535A (en) 2017-01-25 2023-06-21 Univ Hong Kong Chinese Diagnostic applications using nucleic acid fragments
EP3740581A4 (en) 2018-01-16 2021-10-27 CLS Therapeutics Limited TREATMENT OF DISEASES BY LIVER EXPRESSION OF AN ENZYME WITH DESOXYRIBONUCLEASE (DNASE) ACTIVITY

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030175713A1 (en) * 2002-02-15 2003-09-18 Clemens Sorg Method for diagnosis of inflammatory diseases using CALGRANULIN C
AU2003304203A1 (en) * 2002-10-29 2005-01-04 Pharmacia Corporation Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
FR2863274B1 (fr) * 2003-12-05 2012-11-16 Commissariat Energie Atomique Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications.
WO2005113824A2 (en) * 2004-05-14 2005-12-01 Zhenghe Wang Protein tyrosine phosphatase mutations in cancers
WO2007012970A1 (en) * 2005-07-28 2007-02-01 Oncostem Pharma, S.L. Graded expression of snail as marker of cancer development and dna damage-based diseases
US20070238094A1 (en) * 2005-12-09 2007-10-11 Baylor Research Institute Diagnosis, prognosis and monitoring of disease progression of systemic lupus erythematosus through blood leukocyte microarray analysis
CN1995384A (zh) * 2006-01-06 2007-07-11 王铸钢 一种快速方便转基因插入位点鉴定技术
CN101153340A (zh) * 2007-09-30 2008-04-02 中国农业大学 一种用于鉴定未知基因序列的连接片断pcr检测方法
JPWO2009057695A1 (ja) * 2007-10-30 2011-03-10 オリンパス株式会社 遺伝子解析による腺腫又はがんの検出方法

Also Published As

Publication number Publication date
WO2011073665A1 (en) 2011-06-23
BR112012014996A2 (pt) 2017-01-31
CA2784613A1 (en) 2011-06-23
IN2012DN06280A (pt) 2015-09-25
EP2513330B1 (en) 2017-03-08
ES2627961T3 (es) 2017-08-01
CA2784613C (en) 2018-03-06
DK2513330T3 (en) 2017-06-19
EP2513330A1 (en) 2012-10-24
US20130122010A1 (en) 2013-05-16
JP2013514075A (ja) 2013-04-25
CN102939389A (zh) 2013-02-20
GB0922006D0 (en) 2010-02-03
JP5963679B2 (ja) 2016-08-03
CN102939389B (zh) 2016-11-16

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements