BR112012014996A2 - método diagnóstico baseado em reaaranjo somaticamente adquirido - Google Patents
método diagnóstico baseado em reaaranjo somaticamente adquiridoInfo
- Publication number
- BR112012014996A2 BR112012014996A2 BR112012014996A BR112012014996A BR112012014996A2 BR 112012014996 A2 BR112012014996 A2 BR 112012014996A2 BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A2 BR112012014996 A2 BR 112012014996A2
- Authority
- BR
- Brazil
- Prior art keywords
- reaaranjo
- diagnostic method
- based diagnostic
- somatically acquired
- somatically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0922006.2A GB0922006D0 (en) | 2009-12-17 | 2009-12-17 | Diagnostic |
PCT/GB2010/052110 WO2011073665A1 (en) | 2009-12-17 | 2010-12-16 | Diagnostic methods based on somatically acquired rearrangement |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112012014996A2 true BR112012014996A2 (pt) | 2017-01-31 |
BR112012014996A8 BR112012014996A8 (pt) | 2018-04-03 |
Family
ID=41717068
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012014996A BR112012014996A8 (pt) | 2009-12-17 | 2010-12-16 | método diagnóstico baseado em rearranjo somaticamente adquirido |
Country Status (11)
Country | Link |
---|---|
US (1) | US20130122010A1 (pt) |
EP (1) | EP2513330B1 (pt) |
JP (1) | JP5963679B2 (pt) |
CN (1) | CN102939389B (pt) |
BR (1) | BR112012014996A8 (pt) |
CA (1) | CA2784613C (pt) |
DK (1) | DK2513330T3 (pt) |
ES (1) | ES2627961T3 (pt) |
GB (1) | GB0922006D0 (pt) |
IN (1) | IN2012DN06280A (pt) |
WO (1) | WO2011073665A1 (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8388951B2 (en) | 2003-07-14 | 2013-03-05 | Cls Therapeutics Limited | Method for treating systemic DNA mutation disease |
US8431123B2 (en) | 2003-07-14 | 2013-04-30 | Cls Therapeutics Limited | Method for treating systemic bacterial, fungal and protozoan infection |
US8710012B2 (en) | 2003-07-14 | 2014-04-29 | Cls Therapeutics Limited | Method for treating oncological diseases |
US8916151B2 (en) | 2005-04-25 | 2014-12-23 | Cls Therapeutics Limited | Method for treating a reduction of fertility |
PL2095825T3 (pl) | 2006-11-28 | 2011-12-30 | Cls Therapeutics Ltd | Sposób leczenia ludzkich chorób związanych ze zwiększoną zawartością kwasu deoksyrybonukleinowego w przestrzeniach pozakomórkowych i tkankach i preparat leczniczy do przeprowadzenia tego sposobu |
EP2536854B1 (en) * | 2010-02-18 | 2017-07-19 | The Johns Hopkins University | Personalized tumor biomarkers |
US11261494B2 (en) * | 2012-06-21 | 2022-03-01 | The Chinese University Of Hong Kong | Method of measuring a fractional concentration of tumor DNA |
US9953130B2 (en) | 2013-10-01 | 2018-04-24 | Life Technologies Corporation | Systems and methods for detecting structural variants |
WO2015184439A1 (en) * | 2014-05-30 | 2015-12-03 | Five3 Genomics, Llc | Systems and methods for comprehensive analysis of molecular profiles across multiple tumor and germline exomes |
US10617743B2 (en) | 2014-06-19 | 2020-04-14 | Cls Therapeutics Limited | Method to improve safety and efficacy of anti-cancer therapy |
PT3256605T (pt) | 2015-02-10 | 2022-03-17 | Univ Hong Kong Chinese | Deteção de mutações para rastreio de cancro e análise fetal |
EP3297657B1 (en) | 2015-05-22 | 2020-03-25 | GENKIN, Dmitry Dmitrievich | Extracellular dna as a therapeutic target in neurodegeneration |
TWI803477B (zh) | 2017-01-25 | 2023-06-01 | 香港中文大學 | 使用核酸片段之診斷應用 |
EP3740581A4 (en) | 2018-01-16 | 2021-10-27 | CLS Therapeutics Limited | TREATMENT OF DISEASES BY LIVER EXPRESSION OF AN ENZYME WITH DESOXYRIBONUCLEASE (DNASE) ACTIVITY |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030175713A1 (en) * | 2002-02-15 | 2003-09-18 | Clemens Sorg | Method for diagnosis of inflammatory diseases using CALGRANULIN C |
AU2003304203A1 (en) * | 2002-10-29 | 2005-01-04 | Pharmacia Corporation | Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same |
FR2863274B1 (fr) * | 2003-12-05 | 2012-11-16 | Commissariat Energie Atomique | Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications. |
US8039210B2 (en) * | 2004-05-14 | 2011-10-18 | The Johns Hopkins University | Protein tyrosine phosphatase mutations in cancers |
JP2009502159A (ja) * | 2005-07-28 | 2009-01-29 | オンコステム ファルマ ソシエダッド リミタード | ガン成長ならびにdna損傷に基づく疾患のマーカーとしてのスネイルの段階的発現 |
US20070238094A1 (en) * | 2005-12-09 | 2007-10-11 | Baylor Research Institute | Diagnosis, prognosis and monitoring of disease progression of systemic lupus erythematosus through blood leukocyte microarray analysis |
CN1995384A (zh) * | 2006-01-06 | 2007-07-11 | 王铸钢 | 一种快速方便转基因插入位点鉴定技术 |
CN101153340A (zh) * | 2007-09-30 | 2008-04-02 | 中国农业大学 | 一种用于鉴定未知基因序列的连接片断pcr检测方法 |
US20100255481A1 (en) * | 2007-10-30 | 2010-10-07 | Olympus Corporation | Method for detection of adenoma or cancer by genetic analysis |
-
2009
- 2009-12-17 GB GBGB0922006.2A patent/GB0922006D0/en not_active Ceased
-
2010
- 2010-12-16 DK DK10801235.2T patent/DK2513330T3/en active
- 2010-12-16 CA CA2784613A patent/CA2784613C/en not_active Expired - Fee Related
- 2010-12-16 WO PCT/GB2010/052110 patent/WO2011073665A1/en active Application Filing
- 2010-12-16 EP EP10801235.2A patent/EP2513330B1/en not_active Not-in-force
- 2010-12-16 CN CN201080064162.1A patent/CN102939389B/zh not_active Expired - Fee Related
- 2010-12-16 ES ES10801235.2T patent/ES2627961T3/es active Active
- 2010-12-16 US US13/516,364 patent/US20130122010A1/en not_active Abandoned
- 2010-12-16 BR BR112012014996A patent/BR112012014996A8/pt not_active Application Discontinuation
- 2010-12-16 JP JP2012543910A patent/JP5963679B2/ja not_active Expired - Fee Related
-
2012
- 2012-07-17 IN IN6280DEN2012 patent/IN2012DN06280A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB0922006D0 (en) | 2010-02-03 |
DK2513330T3 (en) | 2017-06-19 |
ES2627961T3 (es) | 2017-08-01 |
IN2012DN06280A (pt) | 2015-09-25 |
WO2011073665A1 (en) | 2011-06-23 |
US20130122010A1 (en) | 2013-05-16 |
EP2513330A1 (en) | 2012-10-24 |
CN102939389B (zh) | 2016-11-16 |
CA2784613C (en) | 2018-03-06 |
EP2513330B1 (en) | 2017-03-08 |
JP2013514075A (ja) | 2013-04-25 |
CN102939389A (zh) | 2013-02-20 |
JP5963679B2 (ja) | 2016-08-03 |
BR112012014996A8 (pt) | 2018-04-03 |
CA2784613A1 (en) | 2011-06-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |