BR112012014996A2 - método diagnóstico baseado em reaaranjo somaticamente adquirido - Google Patents

método diagnóstico baseado em reaaranjo somaticamente adquirido

Info

Publication number
BR112012014996A2
BR112012014996A2 BR112012014996A BR112012014996A BR112012014996A2 BR 112012014996 A2 BR112012014996 A2 BR 112012014996A2 BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A BR112012014996 A BR 112012014996A BR 112012014996 A2 BR112012014996 A2 BR 112012014996A2
Authority
BR
Brazil
Prior art keywords
reaaranjo
diagnostic method
based diagnostic
somatically acquired
somatically
Prior art date
Application number
BR112012014996A
Other languages
English (en)
Other versions
BR112012014996A8 (pt
Inventor
John Campbell Peter
Original Assignee
Genome Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Res Ltd filed Critical Genome Res Ltd
Publication of BR112012014996A2 publication Critical patent/BR112012014996A2/pt
Publication of BR112012014996A8 publication Critical patent/BR112012014996A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
BR112012014996A 2009-12-17 2010-12-16 método diagnóstico baseado em rearranjo somaticamente adquirido BR112012014996A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0922006.2A GB0922006D0 (en) 2009-12-17 2009-12-17 Diagnostic
PCT/GB2010/052110 WO2011073665A1 (en) 2009-12-17 2010-12-16 Diagnostic methods based on somatically acquired rearrangement

Publications (2)

Publication Number Publication Date
BR112012014996A2 true BR112012014996A2 (pt) 2017-01-31
BR112012014996A8 BR112012014996A8 (pt) 2018-04-03

Family

ID=41717068

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014996A BR112012014996A8 (pt) 2009-12-17 2010-12-16 método diagnóstico baseado em rearranjo somaticamente adquirido

Country Status (11)

Country Link
US (1) US20130122010A1 (pt)
EP (1) EP2513330B1 (pt)
JP (1) JP5963679B2 (pt)
CN (1) CN102939389B (pt)
BR (1) BR112012014996A8 (pt)
CA (1) CA2784613C (pt)
DK (1) DK2513330T3 (pt)
ES (1) ES2627961T3 (pt)
GB (1) GB0922006D0 (pt)
IN (1) IN2012DN06280A (pt)
WO (1) WO2011073665A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8388951B2 (en) 2003-07-14 2013-03-05 Cls Therapeutics Limited Method for treating systemic DNA mutation disease
US8431123B2 (en) 2003-07-14 2013-04-30 Cls Therapeutics Limited Method for treating systemic bacterial, fungal and protozoan infection
US8710012B2 (en) 2003-07-14 2014-04-29 Cls Therapeutics Limited Method for treating oncological diseases
US8916151B2 (en) 2005-04-25 2014-12-23 Cls Therapeutics Limited Method for treating a reduction of fertility
PL2095825T3 (pl) 2006-11-28 2011-12-30 Cls Therapeutics Ltd Sposób leczenia ludzkich chorób związanych ze zwiększoną zawartością kwasu deoksyrybonukleinowego w przestrzeniach pozakomórkowych i tkankach i preparat leczniczy do przeprowadzenia tego sposobu
EP2536854B1 (en) * 2010-02-18 2017-07-19 The Johns Hopkins University Personalized tumor biomarkers
US11261494B2 (en) * 2012-06-21 2022-03-01 The Chinese University Of Hong Kong Method of measuring a fractional concentration of tumor DNA
US9953130B2 (en) 2013-10-01 2018-04-24 Life Technologies Corporation Systems and methods for detecting structural variants
WO2015184439A1 (en) * 2014-05-30 2015-12-03 Five3 Genomics, Llc Systems and methods for comprehensive analysis of molecular profiles across multiple tumor and germline exomes
US10617743B2 (en) 2014-06-19 2020-04-14 Cls Therapeutics Limited Method to improve safety and efficacy of anti-cancer therapy
PT3256605T (pt) 2015-02-10 2022-03-17 Univ Hong Kong Chinese Deteção de mutações para rastreio de cancro e análise fetal
EP3297657B1 (en) 2015-05-22 2020-03-25 GENKIN, Dmitry Dmitrievich Extracellular dna as a therapeutic target in neurodegeneration
TWI803477B (zh) 2017-01-25 2023-06-01 香港中文大學 使用核酸片段之診斷應用
EP3740581A4 (en) 2018-01-16 2021-10-27 CLS Therapeutics Limited TREATMENT OF DISEASES BY LIVER EXPRESSION OF AN ENZYME WITH DESOXYRIBONUCLEASE (DNASE) ACTIVITY

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030175713A1 (en) * 2002-02-15 2003-09-18 Clemens Sorg Method for diagnosis of inflammatory diseases using CALGRANULIN C
AU2003304203A1 (en) * 2002-10-29 2005-01-04 Pharmacia Corporation Differentially expressed genes involved in cancer, the polypeptides encoded thereby, and methods of using the same
FR2863274B1 (fr) * 2003-12-05 2012-11-16 Commissariat Energie Atomique Procede d'evaluation quantitative d'un rearrangement ou d'une recombinaison genetique ciblee d'un individu et ses applications.
US8039210B2 (en) * 2004-05-14 2011-10-18 The Johns Hopkins University Protein tyrosine phosphatase mutations in cancers
JP2009502159A (ja) * 2005-07-28 2009-01-29 オンコステム ファルマ ソシエダッド リミタード ガン成長ならびにdna損傷に基づく疾患のマーカーとしてのスネイルの段階的発現
US20070238094A1 (en) * 2005-12-09 2007-10-11 Baylor Research Institute Diagnosis, prognosis and monitoring of disease progression of systemic lupus erythematosus through blood leukocyte microarray analysis
CN1995384A (zh) * 2006-01-06 2007-07-11 王铸钢 一种快速方便转基因插入位点鉴定技术
CN101153340A (zh) * 2007-09-30 2008-04-02 中国农业大学 一种用于鉴定未知基因序列的连接片断pcr检测方法
US20100255481A1 (en) * 2007-10-30 2010-10-07 Olympus Corporation Method for detection of adenoma or cancer by genetic analysis

Also Published As

Publication number Publication date
GB0922006D0 (en) 2010-02-03
DK2513330T3 (en) 2017-06-19
ES2627961T3 (es) 2017-08-01
IN2012DN06280A (pt) 2015-09-25
WO2011073665A1 (en) 2011-06-23
US20130122010A1 (en) 2013-05-16
EP2513330A1 (en) 2012-10-24
CN102939389B (zh) 2016-11-16
CA2784613C (en) 2018-03-06
EP2513330B1 (en) 2017-03-08
JP2013514075A (ja) 2013-04-25
CN102939389A (zh) 2013-02-20
JP5963679B2 (ja) 2016-08-03
BR112012014996A8 (pt) 2018-04-03
CA2784613A1 (en) 2011-06-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements