BR0313019A - Compostos que se ligam a p-selectina - Google Patents
Compostos que se ligam a p-selectinaInfo
- Publication number
- BR0313019A BR0313019A BR0313019-3A BR0313019A BR0313019A BR 0313019 A BR0313019 A BR 0313019A BR 0313019 A BR0313019 A BR 0313019A BR 0313019 A BR0313019 A BR 0313019A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- selectin
- binding
- bind
- derivatives
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 101000622137 Homo sapiens P-selectin Proteins 0.000 abstract 1
- 108010035766 P-Selectin Proteins 0.000 abstract 1
- 102000008212 P-Selectin Human genes 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02078308 | 2002-08-09 | ||
| PCT/EP2003/007260 WO2004018502A1 (en) | 2002-08-09 | 2003-07-04 | Compounds binding to p-selectin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0313019A true BR0313019A (pt) | 2005-07-12 |
Family
ID=31896910
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0313019-3A BR0313019A (pt) | 2002-08-09 | 2003-07-04 | Compostos que se ligam a p-selectina |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US20060217294A1 (enExample) |
| EP (1) | EP1527086B1 (enExample) |
| JP (2) | JP4563806B2 (enExample) |
| AT (1) | ATE383370T1 (enExample) |
| AU (1) | AU2003250899A1 (enExample) |
| BR (1) | BR0313019A (enExample) |
| CA (1) | CA2493471C (enExample) |
| DE (1) | DE60318585T2 (enExample) |
| ES (1) | ES2299749T3 (enExample) |
| MX (1) | MXPA05001599A (enExample) |
| WO (1) | WO2004018502A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1527086B1 (en) * | 2002-08-09 | 2008-01-09 | Astellas Pharma Europe B.V. | Compounds binding to p-selectin |
| ATE444301T1 (de) | 2002-10-11 | 2009-10-15 | Astellas Pharma Europ B V | Verbindungen auf glukosebasis mit affinitüt für p-selektin |
| EP1577289A1 (en) * | 2004-03-18 | 2005-09-21 | Revotar Biopharmaceuticals AG | Non-glycosylated/-glycosidic/-peptidic small molecule selectin inhibitors for the treament of inflammatory disorders |
| EP1764093A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel aromatic compounds and their use in medical applications |
| EP1764095A1 (en) * | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel nitrocatechol derivatives having selectin ligand activity |
| EP1764096A1 (en) | 2005-09-20 | 2007-03-21 | Revotar Biopharmaceuticals AG | Novel phloroglucinol derivatives having selectin ligand activity |
| BRPI0716554A2 (pt) * | 2006-09-08 | 2013-09-24 | Bayer Schering Pharma Ag | compostos de mÉtodos para agentes rotulados de 18f |
| HUE034308T2 (en) | 2013-03-21 | 2018-02-28 | Sanofi Aventis Deutschland | Preparation of hydantoin-containing peptide products |
| US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
| AU2021208650A1 (en) * | 2020-01-16 | 2022-08-11 | Case Western Reserve University | Neutrophil elastase binding peptides and compositions thereof |
| CN115039782A (zh) * | 2022-07-20 | 2022-09-13 | 中国农业科学院植物保护研究所 | 一种化合物在大豆孢囊线虫几丁质酶抑制剂中的应用 |
| WO2025168211A1 (en) | 2023-02-10 | 2025-08-14 | Novo Nordisk A/S | P-selectin peptide ligands |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005314A1 (en) * | 1992-09-08 | 1994-03-17 | Centocor, Inc. | Peptide inhibitors of leukocyte adhesion |
| AU2958195A (en) * | 1994-06-29 | 1996-01-25 | Texas Biotechnology Corporation | Process to inhibit binding of the integrin alpha 4 beta 1 to vcam-1 or fibronectin |
| WO2000027420A1 (en) * | 1998-11-06 | 2000-05-18 | The Wistar Institute Of Anatomy And Biology | Compositions and methods for treatment of cancer |
| EP1288222A1 (en) * | 2001-09-03 | 2003-03-05 | Yamanouchi Europe B.V. | Peptidic compounds selectively binding to P-selectin |
| EP1527086B1 (en) * | 2002-08-09 | 2008-01-09 | Astellas Pharma Europe B.V. | Compounds binding to p-selectin |
-
2003
- 2003-07-04 EP EP03792179A patent/EP1527086B1/en not_active Expired - Lifetime
- 2003-07-04 AT AT03792179T patent/ATE383370T1/de not_active IP Right Cessation
- 2003-07-04 US US10/524,172 patent/US20060217294A1/en not_active Abandoned
- 2003-07-04 ES ES03792179T patent/ES2299749T3/es not_active Expired - Lifetime
- 2003-07-04 MX MXPA05001599A patent/MXPA05001599A/es unknown
- 2003-07-04 WO PCT/EP2003/007260 patent/WO2004018502A1/en not_active Ceased
- 2003-07-04 JP JP2004530000A patent/JP4563806B2/ja not_active Expired - Fee Related
- 2003-07-04 CA CA2493471A patent/CA2493471C/en not_active Expired - Fee Related
- 2003-07-04 BR BR0313019-3A patent/BR0313019A/pt not_active Application Discontinuation
- 2003-07-04 DE DE60318585T patent/DE60318585T2/de not_active Expired - Lifetime
- 2003-07-04 AU AU2003250899A patent/AU2003250899A1/en not_active Abandoned
-
2008
- 2008-06-25 US US12/146,302 patent/US20090062186A1/en not_active Abandoned
-
2010
- 2010-03-16 US US12/725,199 patent/US20100323969A1/en not_active Abandoned
- 2010-04-21 JP JP2010098138A patent/JP2010209088A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ES2299749T3 (es) | 2008-06-01 |
| WO2004018502A8 (en) | 2005-05-12 |
| US20090062186A1 (en) | 2009-03-05 |
| ATE383370T1 (de) | 2008-01-15 |
| MXPA05001599A (es) | 2005-08-19 |
| WO2004018502A1 (en) | 2004-03-04 |
| DE60318585T2 (de) | 2009-01-08 |
| JP2010209088A (ja) | 2010-09-24 |
| EP1527086B1 (en) | 2008-01-09 |
| EP1527086A1 (en) | 2005-05-04 |
| US20060217294A1 (en) | 2006-09-28 |
| US20100323969A1 (en) | 2010-12-23 |
| CA2493471C (en) | 2013-02-12 |
| CA2493471A1 (en) | 2004-03-04 |
| JP2006513141A (ja) | 2006-04-20 |
| DE60318585D1 (de) | 2008-02-21 |
| JP4563806B2 (ja) | 2010-10-13 |
| AU2003250899A1 (en) | 2004-03-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004025101D1 (de) | Humane anti-humane cd3-bindungsmoleküle | |
| BRPI0513681A (pt) | composição que compreendem anticorpo her2, método, formulações farmacêuticas, polipeptìdeo, anticorpo e método de tratamento de cáncer | |
| IS7965A (is) | Þíenópýrimidíndíón og notkun þeirra í breytingu ásjálfsnæmissjúkdómi | |
| BRPI0417684A (pt) | composto, composição farmacêutica, e, uso de um composto | |
| EA200100968A1 (ru) | Димерные соединения и их применение в качестве ингибиторов нейраминидазы | |
| ATE517638T1 (de) | Verfahren und zubereitungen zum verabreichen von therapeutischen und diagnostischen mitteln | |
| CA2413190A1 (en) | Methods for treating rheumatic diseases using a soluble ctla4 molecule | |
| CY1113069T1 (el) | Μεθοδοι παρασκευης συνθεσεων ξηρης σκονης του γλυκοπυρρολικου | |
| DE602007009995D1 (de) | Muteine von tearlipocalin und verfahren zu deren gewinnung | |
| BRPI0411505A (pt) | uso de um composto, método para modular a resposta imune de um indivìduo, composição farmacêutica, vacina, complexo, e, kit para a captura de uma molécula biologicamente ativa | |
| SG144925A1 (en) | Methods for treating cardiovascular disease using a soluble ctla4 molecule | |
| CY1109168T1 (el) | Συνθεση νατριουχου φονταπαρινοξης υψηλης καθαροτητας | |
| CY1109722T1 (el) | Ενδιαμεσες ενωσεις για την παρασκευη της trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,73oxepino[4,5-c]pyrrole | |
| CY1106386T1 (el) | Υποκατεστημενα παραγωγα 3-πυρρολιδιν-ινδολης | |
| EA200700096A1 (ru) | Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии | |
| ATE383370T1 (de) | Verbindungen die p-selectin binden | |
| ATE422356T1 (de) | Pharmazeutische zubereitungen | |
| DE60336225D1 (de) | Neue pharmazeutische zusammenstezungen, flibanserin polymorph a enthaltend | |
| BR0308606A (pt) | Derivados de hemiasterlina e usos destes | |
| BR0012478A (pt) | Derivados de aminotiazóis, sua preparação e composição farmacêuticas contendo os mesmos | |
| CY1109537T1 (el) | Πεπτιδια και παραγωγα πεπτιδιου, παρασκευη αυτων καθως επισης χρηση αυτων για την παρασκευη θεραπευτικως η/και προληπτικως δραστικης φαρμακευτικης συνθεσης | |
| BR0311491A (pt) | Composto, composição farmacêutica, uso de um composto, e, método terapêutico para tratar câncer em um mamìfero | |
| BRPI0407031A (pt) | Composições e métodos para tratamento de câncer empregando igsf9 e liv-1 | |
| EA200702375A1 (ru) | Производные мочевины, способы их получения и применения | |
| DE502007002949D1 (de) | Proteinbindende methotrexat-derivate und diese enthaltende arzneimittel |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |