BR0311952A - Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do snc - Google Patents
Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do sncInfo
- Publication number
- BR0311952A BR0311952A BR0311952-1A BR0311952A BR0311952A BR 0311952 A BR0311952 A BR 0311952A BR 0311952 A BR0311952 A BR 0311952A BR 0311952 A BR0311952 A BR 0311952A
- Authority
- BR
- Brazil
- Prior art keywords
- diabetes
- type
- compounds useful
- new compounds
- treating obesity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0201925A SE0201925D0 (sv) | 2002-06-20 | 2002-06-20 | New compounds |
SE0202181A SE0202181D0 (sv) | 2002-07-11 | 2002-07-11 | New compounds |
US40612002P | 2002-08-26 | 2002-08-26 | |
SE0202908A SE0202908D0 (sv) | 2002-10-01 | 2002-10-01 | New compounds |
US43401002P | 2002-12-17 | 2002-12-17 | |
SE0300357A SE0300357D0 (sv) | 2003-02-10 | 2003-02-10 | New compounds |
US46470103P | 2003-04-23 | 2003-04-23 | |
PCT/SE2003/001061 WO2004000828A1 (en) | 2002-06-20 | 2003-06-19 | New compounds useful for the treatment of obesity, type ii diabetes and cns disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0311952A true BR0311952A (pt) | 2005-04-19 |
Family
ID=30004107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0311952-1A BR0311952A (pt) | 2002-06-20 | 2003-06-19 | Novos compostos úteis para o tratamento de obesidade, diabetes tipo ii e distúrbios do snc |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1513828A1 (zh) |
CN (1) | CN1662521A (zh) |
AU (1) | AU2003243091A1 (zh) |
BR (1) | BR0311952A (zh) |
CA (1) | CA2486989A1 (zh) |
EA (2) | EA008835B1 (zh) |
IL (1) | IL165051A0 (zh) |
MX (1) | MXPA04012914A (zh) |
NO (1) | NO20050294L (zh) |
NZ (3) | NZ552283A (zh) |
RS (1) | RS111204A (zh) |
SG (1) | SG156524A1 (zh) |
WO (1) | WO2004000828A1 (zh) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL209872B1 (pl) | 2002-03-27 | 2011-10-31 | Glaxo Group Ltd | Pochodna chinolinowa, sposób jej wytwarzania i jej zastosowanie oraz zawierająca ją farmaceutyczna kompozycja |
SE0301446D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | New Compounds |
TWI328009B (en) | 2003-05-21 | 2010-08-01 | Glaxo Group Ltd | Quinoline derivatives as phosphodiesterase inhibitors |
RS20060035A (en) | 2003-07-22 | 2008-08-07 | Arena Pharmaceuticals Inc., | Diaryl and arylheteroaryl urea derivatives as modulators of the 5-ht2a serotonin receptor useful for the prophylaxis and treatment of disorders related thereto |
SE0302760D0 (sv) * | 2003-10-20 | 2003-10-20 | Biovitrum Ab | New compounds |
AU2004299438A1 (en) * | 2003-12-19 | 2005-06-30 | Biovitrum Ab | Novel benzofuran derivatives, which can be used in prophylaxis or treatment of 5-HT6 receptor-related disorder |
SE0303480D0 (sv) | 2003-12-19 | 2003-12-19 | Biovitrum Ab | Benzofuranes |
GB0407025D0 (en) * | 2004-03-29 | 2004-04-28 | Glaxo Group Ltd | Novel compounds |
CA2563895C (en) * | 2004-04-13 | 2012-10-16 | Synta Pharmaceuticals Corp. | Disalt inhibitors of il-12 production |
WO2006062481A1 (en) * | 2004-12-09 | 2006-06-15 | Biovitrum Ab | New benzofuran derivatives and their use in the treatment of obesity, type ii diabetes and cns disorders . |
AR054044A1 (es) * | 2005-05-23 | 2007-05-30 | Astrazeneca Ab | Derivados de cromano y tetrahidronaftaleno como moduladores del receptor 5 - ht6; intermediarios en su preparacion; composiciones farmaceuticas que los contienen y su empelo en la fabricacion de medicamentos para el tratamiento de enfermedades del snc y de la obesidad. |
US7582767B2 (en) * | 2005-06-17 | 2009-09-01 | Biovitrum Ab (Publ.) | Substituted sulphonamide compound and uses thereof |
JP2008545008A (ja) * | 2005-06-30 | 2008-12-11 | プロシディオン・リミテッド | Gpcrアゴニスト |
JP5270353B2 (ja) | 2005-10-07 | 2013-08-21 | エクセリクシス, インク. | ホスファチジルイノシトール3−キナーゼインヒビターとその使用方法 |
RU2008115032A (ru) | 2005-11-03 | 2009-12-10 | Ф. Хоффманн-Ля Рош Аг (Ch) | Арилсульфонилхроманы в качестве ингибиторов 5-нт6 |
UY30048A1 (es) | 2005-12-23 | 2007-07-31 | Astrazeneca Ab | Derivados sustituidos de la n,2-(1h-benzimidazol-1-il) acetamida, composiciones farmacéuticas conteniéndolos, procesos de preparación y aplicaciones |
JP2009541249A (ja) | 2006-06-20 | 2009-11-26 | エフ.ホフマン−ラ ロシュ アーゲー | アリールスルホニルナフタレン誘導体およびその使用 |
BRPI0713736A2 (pt) | 2006-06-20 | 2014-11-18 | Hoffmann La Roche | Derivados de tetralina e indano e emprego destes |
CN101472883A (zh) | 2006-06-20 | 2009-07-01 | 弗·哈夫曼-拉罗切有限公司 | 芳基磺酰氨基四氢萘衍生物以及其应用 |
TWI433839B (zh) | 2006-08-11 | 2014-04-11 | Neomed Inst | 新穎的苯并咪唑衍生物290 |
WO2009074607A1 (en) | 2007-12-12 | 2009-06-18 | Glaxo Group Limited | Combinations comprising 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline |
WO2009123714A2 (en) | 2008-04-02 | 2009-10-08 | Arena Pharmaceuticals, Inc. | Processes for the preparation of pyrazole derivatives useful as modulators of the 5-ht2a serotonin receptor |
US7888662B2 (en) | 2008-06-20 | 2011-02-15 | Varian Semiconductor Equipment Associates, Inc. | Ion source cleaning method and apparatus |
US9126946B2 (en) | 2008-10-28 | 2015-09-08 | Arena Pharmaceuticals, Inc. | Processes useful for the preparation of 1-[3-(4-bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxy-phenyl]-3-(2,4-difluoro-phenyl)urea and crystalline forms related thereto |
JP5872027B2 (ja) * | 2011-05-09 | 2016-03-01 | フォーマ ティーエム, エルエルシー. | ニコチンアミドホスホリボシルトランスフェラーゼ(nampt)を阻害するためのピペリジン誘導体および組成物 |
JP6454346B2 (ja) | 2013-12-20 | 2019-01-16 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. | 芳香族複素環式化合物及び医薬におけるその応用 |
CN109562085A (zh) | 2015-06-12 | 2019-04-02 | 阿速万科学有限责任公司 | 用于预防和治疗rem睡眠行为障碍的二芳基和芳基杂芳基脲衍生物 |
AU2016291673A1 (en) | 2015-07-15 | 2018-01-25 | Axovant Sciences Gmbh | Diaryl and arylheteroaryl urea derivatives for the prophylaxis and treatment of hallucinations associated with a neurodegenerative disease |
WO2017147328A1 (en) | 2016-02-23 | 2017-08-31 | Portola Pharmaceuticals, Inc. | Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9) |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB947606A (en) * | 1961-04-10 | 1964-01-22 | Ici Ltd | N-substituted piperazines |
US4808595A (en) * | 1986-12-24 | 1989-02-28 | Merck & Co., Inc. | Furopyridine sulfonamides and their opthalmological compositions |
PT689536E (pt) * | 1993-03-16 | 2001-11-30 | Pfizer | Derivados de naftaleno |
US5597826A (en) * | 1994-09-14 | 1997-01-28 | Pfizer Inc. | Compositions containing sertraline and a 5-HT1D receptor agonist or antagonist |
DZ2376A1 (fr) * | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
GB9818916D0 (en) * | 1998-08-28 | 1998-10-21 | Smithkline Beecham Plc | Use |
GB9904995D0 (en) * | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Substituted aza-oxindole derivatives |
WO2001032660A1 (en) * | 1999-11-05 | 2001-05-10 | Nps Allelix Corp. | Compounds having 5-ht6 receptor antagonist activity |
GB9926302D0 (en) * | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
CA2408156A1 (en) * | 2000-05-05 | 2001-11-15 | Millennium Pharmaceuticals, Inc. | Heterobicyclic sulfonamides and their use as platelet adp receptor inhibitors |
US6943174B2 (en) * | 2000-06-14 | 2005-09-13 | Warner-Lambert Company | 6,5-Fused bicyclic heterocycles |
MXPA03003397A (es) * | 2000-10-20 | 2004-06-30 | Biovitrum Ab | N1-(bencensulfonil)indoles sustituidos en las posiciones 2-, 3-, 4-, o 5 y su uso en terapia. |
NZ528450A (en) * | 2001-05-11 | 2006-02-24 | Biovitrum Ab | Novel, arylsulfonamide compounds for the treatment of obesity, type II diabetes and CNS-disorders |
NZ529631A (en) * | 2001-06-07 | 2006-08-31 | F | Indole derivatives with 5-hydroxytryptamine (5-HT) 5-HT6 receptor affinity in the treatment of disorders of the CNS |
WO2002100822A1 (en) * | 2001-06-11 | 2002-12-19 | Biovitrum Ab | Substituted sulfonamide compounds, process for their use as medicament for the treatment of cns disorders, obesity and type ii diabetes |
-
2003
- 2003-06-19 AU AU2003243091A patent/AU2003243091A1/en not_active Abandoned
- 2003-06-19 EP EP03760999A patent/EP1513828A1/en not_active Ceased
- 2003-06-19 EA EA200500054A patent/EA008835B1/ru not_active IP Right Cessation
- 2003-06-19 NZ NZ552283A patent/NZ552283A/en unknown
- 2003-06-19 CA CA002486989A patent/CA2486989A1/en not_active Abandoned
- 2003-06-19 RS YU111204A patent/RS111204A/sr unknown
- 2003-06-19 WO PCT/SE2003/001061 patent/WO2004000828A1/en active Application Filing
- 2003-06-19 MX MXPA04012914A patent/MXPA04012914A/es not_active Application Discontinuation
- 2003-06-19 NZ NZ552282A patent/NZ552282A/en unknown
- 2003-06-19 CN CN038144328A patent/CN1662521A/zh active Pending
- 2003-06-19 SG SG200604188-3A patent/SG156524A1/en unknown
- 2003-06-19 BR BR0311952-1A patent/BR0311952A/pt not_active IP Right Cessation
- 2003-06-19 NZ NZ536600A patent/NZ536600A/en unknown
- 2003-06-19 EA EA200600975A patent/EA011581B1/ru not_active IP Right Cessation
-
2004
- 2004-11-04 IL IL16505104A patent/IL165051A0/xx unknown
-
2005
- 2005-01-19 NO NO20050294A patent/NO20050294L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IL165051A0 (en) | 2005-12-18 |
RS111204A (en) | 2006-12-15 |
EA200500054A1 (ru) | 2005-06-30 |
EA008835B1 (ru) | 2007-08-31 |
EA011581B1 (ru) | 2009-04-28 |
CA2486989A1 (en) | 2003-12-31 |
EP1513828A1 (en) | 2005-03-16 |
WO2004000828A1 (en) | 2003-12-31 |
AU2003243091A1 (en) | 2004-01-06 |
EA200600975A1 (ru) | 2006-10-27 |
MXPA04012914A (es) | 2005-03-31 |
SG156524A1 (en) | 2009-11-26 |
CN1662521A (zh) | 2005-08-31 |
NZ536600A (en) | 2007-08-31 |
NZ552283A (en) | 2008-07-31 |
NO20050294L (no) | 2005-02-04 |
NZ552282A (en) | 2008-07-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: BIOVITRUM AB (PUBL) (SE) Free format text: ALTERADO DE: BIOVITRUM AB |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: PARA INT.CL: C07D 207/12, C07D 211/40, C07D 211/46, C07D 215/46, C07D 217/22, C07D 401/04, C07D 406/12, C07D 471/04, C07D 495/04, A61K 31/40, A61K 31/4025, A61K 31/4353, A61K 31/4465, A61K 31/4523, A61K 31/496, A61K 31/551, A61P 25/00, A61P 3/04, A61P 3/10, A61P 3/00, A61P 43/00 Ipc: C07D 401/04 (2011.01), C07D 495/04 (2011.01), C07D |
|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE 8A. ANUIDADE(S). |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE A 8A ANUIDADE. |