BR0311909A - Métodos para a manufatura de uma composição, e para aumentar a capacidade de metilação de um indivìduo, e, composição farmacêutica ou nutricional - Google Patents
Métodos para a manufatura de uma composição, e para aumentar a capacidade de metilação de um indivìduo, e, composição farmacêutica ou nutricionalInfo
- Publication number
- BR0311909A BR0311909A BR0311909-2A BR0311909A BR0311909A BR 0311909 A BR0311909 A BR 0311909A BR 0311909 A BR0311909 A BR 0311909A BR 0311909 A BR0311909 A BR 0311909A
- Authority
- BR
- Brazil
- Prior art keywords
- composition
- pharmaceutical
- individual
- increasing
- methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 7
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 235000016709 nutrition Nutrition 0.000 title abstract 2
- 230000011987 methylation Effects 0.000 title 1
- 238000007069 methylation reaction Methods 0.000 title 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 2
- 239000000370 acceptor Substances 0.000 abstract 2
- 235000019152 folic acid Nutrition 0.000 abstract 2
- FSYKKLYZXJSNPZ-UHFFFAOYSA-N sarcosine Chemical compound C[NH2+]CC([O-])=O FSYKKLYZXJSNPZ-UHFFFAOYSA-N 0.000 abstract 2
- ZKHQWZAMYRWXGA-KQYNXXCUSA-J ATP(4-) Chemical class C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-J 0.000 abstract 1
- ZKHQWZAMYRWXGA-UHFFFAOYSA-N Adenosine triphosphate Chemical class C1=NC=2C(N)=NC=NC=2N1C1OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C1O ZKHQWZAMYRWXGA-UHFFFAOYSA-N 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-N Betaine Natural products C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 abstract 1
- HMFHBZSHGGEWLO-SOOFDHNKSA-N D-ribofuranose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H]1O HMFHBZSHGGEWLO-SOOFDHNKSA-N 0.000 abstract 1
- JZNWSCPGTDBMEW-UHFFFAOYSA-N Glycerophosphorylethanolamin Natural products NCCOP(O)(=O)OCC(O)CO JZNWSCPGTDBMEW-UHFFFAOYSA-N 0.000 abstract 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- KWIUHFFTVRNATP-UHFFFAOYSA-O N,N,N-trimethylglycinium Chemical compound C[N+](C)(C)CC(O)=O KWIUHFFTVRNATP-UHFFFAOYSA-O 0.000 abstract 1
- FFDGPVCHZBVARC-UHFFFAOYSA-N N,N-dimethylglycine Chemical compound CN(C)CC(O)=O FFDGPVCHZBVARC-UHFFFAOYSA-N 0.000 abstract 1
- PYMYPHUHKUWMLA-LMVFSUKVSA-N Ribose Natural products OC[C@@H](O)[C@@H](O)[C@@H](O)C=O PYMYPHUHKUWMLA-LMVFSUKVSA-N 0.000 abstract 1
- MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical class O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 abstract 1
- 108010077895 Sarcosine Proteins 0.000 abstract 1
- RZCIEJXAILMSQK-JXOAFFINSA-N TTP Chemical class O=C1NC(=O)C(C)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O1 RZCIEJXAILMSQK-JXOAFFINSA-N 0.000 abstract 1
- 229960001570 ademetionine Drugs 0.000 abstract 1
- HMFHBZSHGGEWLO-UHFFFAOYSA-N alpha-D-Furanose-Ribose Natural products OCC1OC(O)C(O)C1O HMFHBZSHGGEWLO-UHFFFAOYSA-N 0.000 abstract 1
- 229960003237 betaine Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 230000015556 catabolic process Effects 0.000 abstract 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001231 choline Drugs 0.000 abstract 1
- 108700003601 dimethylglycine Proteins 0.000 abstract 1
- 229940031098 ethanolamine Drugs 0.000 abstract 1
- 229940014144 folate Drugs 0.000 abstract 1
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 abstract 1
- 239000011724 folic acid Substances 0.000 abstract 1
- 150000002224 folic acids Chemical class 0.000 abstract 1
- 230000006609 metabolic stress Effects 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 229960004452 methionine Drugs 0.000 abstract 1
- WTJKGGKOPKCXLL-RRHRGVEJSA-N phosphatidylcholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCCCCCCC=CCCCCCCCC WTJKGGKOPKCXLL-RRHRGVEJSA-N 0.000 abstract 1
- 150000008104 phosphatidylethanolamines Chemical class 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229940043230 sarcosine Drugs 0.000 abstract 1
- 229960001153 serine Drugs 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P35/00—Antineoplastic agents
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Mycology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Reproductive Health (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Emergency Medicine (AREA)
Abstract
"MéTODOS PARA A MANUFATURA DE UMA COMPOSIçãO, E PARA AUMENTAR A CAPACIDADE DE METILAçãO DE UM INDIVìDUO, E, COMPOSIçãO FARMACêUTICA OU NUTRICIONAL". A invenção refere-se a um método e a uma composição para o tratamento ou a prevenção de catabolismo ou de estimulação de anabolismo em um mamífero sofrendo de estresse metabólico. O método compreende a administração ao mamífero de uma composição contendo doadores de metila selecionados do grupo consistindo de L-serina, metionina, colina, fosfatidil-colina, betaína, dimetil-glicina, sarcosina, folatos metilados, S-adenosil-metionina, timidina-trifosfato, adenosina-trifosfato e opcionalmente aceptores de metila selecionados do grupo consistindo de L-glicina, etanol-amina, fosfatidil etanol-amina, folato, ribose, no qual a quantidade molar total de doadores de metila fornecida pelo método excede a quantidade molar total de aceptores de metila fornecida pelo método em pelo menos 0,18 mmol por kg de peso corporal por dia.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02077434 | 2002-06-19 | ||
US45253703P | 2003-03-07 | 2003-03-07 | |
PCT/NL2003/000449 WO2004000042A2 (en) | 2002-06-19 | 2003-06-19 | Method and composition for treating or preventing catabolism or stimulating anabolism in a mammal undergoing metabolic stress |
Publications (2)
Publication Number | Publication Date |
---|---|
BR0311909A true BR0311909A (pt) | 2005-04-05 |
BRPI0311909A8 BRPI0311909A8 (pt) | 2018-02-06 |
Family
ID=30001854
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0311909A BRPI0311909A8 (pt) | 2002-06-19 | 2003-06-19 | Métodos para a manufatura de uma composição, e para aumentar a capacidade de metilação de um indivíduo, e, composição farmacêutica ou nutricional |
Country Status (7)
Country | Link |
---|---|
EP (3) | EP3184107A1 (pt) |
JP (1) | JP2005529980A (pt) |
CN (1) | CN100469361C (pt) |
AU (1) | AU2003247225A1 (pt) |
BR (1) | BRPI0311909A8 (pt) |
PL (1) | PL375076A1 (pt) |
WO (1) | WO2004000042A2 (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19836339B4 (de) | 1998-08-11 | 2011-12-22 | N.V. Nutricia | Kohlenhydratmischung |
EP1597978A1 (en) | 2004-05-17 | 2005-11-23 | Nutricia N.V. | Synergism of GOS and polyfructose |
US8252769B2 (en) | 2004-06-22 | 2012-08-28 | N. V. Nutricia | Intestinal barrier integrity |
EP1723951A1 (en) * | 2005-04-21 | 2006-11-22 | N.V. Nutricia | Nutritional supplement with oligosaccharides for a category of HIV patients |
EP1645276A1 (en) * | 2004-10-08 | 2006-04-12 | Wageningen Centre for Food Sciences | Treatment of neurodegenerative disorders |
WO2006052134A2 (en) * | 2004-11-12 | 2006-05-18 | N.V. Nutricia | Food composition comprising a protein- and a lipid fraction for rapidly attenuating inflammatory responses |
EP1680967A1 (fr) * | 2005-01-14 | 2006-07-19 | Forum Media Productions SPRL | Compositions diététiques à base d'isolat de protéines solubles de lait |
US20060217386A1 (en) * | 2005-03-10 | 2006-09-28 | Edwards John B | Nutritional preparations |
DK2258219T4 (da) * | 2005-04-27 | 2022-08-29 | Nutricia Nv | Næring med lipider og ikke-fordøjelige saccharider |
PL1909601T3 (pl) * | 2005-08-02 | 2014-03-31 | Alzchem Ag | Ciekły preparat zawierający składnik na bazie kwasu guanidynooctowego |
EP1774973A1 (en) * | 2005-10-12 | 2007-04-18 | Nutricia N.V. | Leucine rich composition |
JP2007209231A (ja) * | 2006-02-08 | 2007-08-23 | Japan Organo Co Ltd | クレアチン含有食品組成物 |
US8835396B2 (en) * | 2006-12-15 | 2014-09-16 | Bioenergy, Inc. | Method and compositions for improving pulmonary hypertension |
DE102007004781A1 (de) | 2007-01-31 | 2008-08-07 | Alzchem Trostberg Gmbh | Verwendung von Guanidinoessigsäure(-Salzen) zur Herstellung eines gesundheitsfördernden Mittels |
ITMI20081405A1 (it) * | 2008-07-29 | 2010-01-30 | Velleja Res Srl | Formulazioni orali istantanee, gelificanti a temperatura ambiente, utili per contrastare il deperimento organico e la sindrome depressiva connessi a cachessia, anoressia, malattia metabolica, malattia endocrina e disfagia |
DE202013006354U1 (de) * | 2013-07-15 | 2014-10-20 | Marianne Brøndlund | Stoffgemisch zur Behandlung von Koagulopathien |
CA3122548A1 (en) | 2016-12-23 | 2018-06-28 | Keio University | Compositions and methods for the induction of cd8+ t-cells |
JP2019024389A (ja) * | 2017-07-28 | 2019-02-21 | 株式会社明治 | 筋力向上用アミノ酸組成物 |
WO2019146735A1 (ja) * | 2018-01-26 | 2019-08-01 | 味の素株式会社 | 侵害受容性疼痛の予防又は改善用組成物 |
WO2019156234A1 (en) * | 2018-02-09 | 2019-08-15 | Keio University | Compositions and methods for the induction of cd8+ t-cells |
AR116213A1 (es) * | 2018-06-20 | 2021-04-14 | Axcella Health Inc | Composiciones para terapia y salud que contienen aminoácidos con sabor amargo |
CN110028570A (zh) * | 2018-10-31 | 2019-07-19 | 华中科技大学 | 一种肌肉素的表达方法及其在代谢疾病中的应用 |
US11767314B2 (en) | 2018-11-02 | 2023-09-26 | Conopco, Inc. | Bioenergetic nicotinic acid glycerol esters, compositions and methods of using same |
HUP2000298A1 (hu) * | 2020-09-11 | 2022-03-28 | Laszlo Gyulai | Vírusfertõzés, elõnyösen SARS-COV-2 és IBV koronavírusok fertõzésének visszaszorítására alkalmazható táplálék-kiegészítõ vagy gyógyászati vagy gyógyszerkészítmény és formulálásuk |
CN117545498A (zh) * | 2021-05-14 | 2024-02-09 | 荷兰医疗食品有限公司 | 用于保持肌肉量的营养组合物 |
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GB696405A (en) * | 1950-12-15 | 1953-08-26 | California Inst Res Found | Improvements in or relating to preparations for muscular and nervous disorders and method of preparing the same |
IL31992A (en) * | 1968-05-08 | 1973-07-30 | American Cyanamid Co | Synthetic thyrocalcitonins and a method for their preparation |
US3873722A (en) * | 1974-05-31 | 1975-03-25 | Nelson Res & Dev | Method for treating schizophrenia |
DE2832009A1 (de) * | 1978-07-20 | 1980-01-31 | Deutsches Krebsforsch | Verwendung von sarkosin und sarkosinderivaten ls tumorhemmende wirksubstanzen |
JPS56110617A (en) * | 1980-02-08 | 1981-09-01 | Ajinomoto Co Inc | Nutrient composition for young child |
US4461724A (en) * | 1981-10-28 | 1984-07-24 | Nippon Zoki Pharmaceutical Co., Ltd. | Peptide compounds, a process for manufacturing them, pharmaceutical compositions containing them, and methods for treating ulcer and thrombus with them |
US5665371A (en) * | 1985-05-20 | 1997-09-09 | Hoerrmann; Wilhelm | Medicines which contain derivatives of proline or hydroxyproline |
US5236899A (en) * | 1987-11-16 | 1993-08-17 | Merck & Co., Inc. | 6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance |
US5026721A (en) * | 1989-06-05 | 1991-06-25 | Dudrick Stanley J | Amino acid nutritional supplement and regimen for enhancing physical performance through sound nutrition |
KR930006993B1 (ko) * | 1989-10-06 | 1993-07-26 | 미쓰이 도오아쓰 가가쿠 가부시키가이샤 | 효소법에 의한 l-세린의 제조법 |
FR2675996B1 (fr) * | 1991-04-30 | 1993-10-15 | Georges Baritiu | Compositions sanogenes dietetiques complexes. |
CA2078019C (en) * | 1991-09-13 | 2002-08-27 | Siegbert Heinrich Bissbort | Substance or composition and uses thereof |
US5856148A (en) * | 1991-12-12 | 1999-01-05 | Wacker Chemie Gmbh | Materials and methods for biosynthesis of serine and serine-related products |
AU685585B2 (en) * | 1994-02-24 | 1998-01-22 | Otsuka Pharmaceutical Factory, Inc. | Analgesic activity enhancer |
US6221836B1 (en) * | 1996-07-26 | 2001-04-24 | Paxton King Beale | Composition of pyruvate and anabolic protein and method for increasing fat loss in a mammal |
EP0891719A1 (en) * | 1997-07-14 | 1999-01-20 | N.V. Nutricia | Nutritional composition containing methionine |
EP1124559B1 (en) * | 1998-10-30 | 2003-03-26 | MERCK PATENT GmbH | Compositions for the treatment and prevention of neurological and pathopsychological diseases |
EP1062879B1 (en) * | 1999-06-26 | 2003-08-27 | B. Braun Melsungen Ag | Aqueous solution for the parenteral nutrition |
US6602532B2 (en) * | 2000-03-03 | 2003-08-05 | F.G.A. Laboratories Flavourence Corporation | Process of preserving food and food preservative |
US7226916B1 (en) | 2000-05-08 | 2007-06-05 | N.V. Nutricia | Preparation for the prevention and/or treatment of vascular disorders |
AU2003247224A1 (en) * | 2002-06-19 | 2004-01-06 | N.V. Nutricia | Nutritional or pharmaceutical compositions for increasing the creatine response of organisms |
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- 2003-06-19 EP EP16199313.4A patent/EP3184107A1/en not_active Withdrawn
- 2003-06-19 JP JP2004530928A patent/JP2005529980A/ja active Pending
- 2003-06-19 BR BRPI0311909A patent/BRPI0311909A8/pt not_active Application Discontinuation
- 2003-06-19 WO PCT/NL2003/000449 patent/WO2004000042A2/en active Application Filing
- 2003-06-19 EP EP20100186325 patent/EP2283835A3/en not_active Ceased
- 2003-06-19 CN CNB038193140A patent/CN100469361C/zh not_active Expired - Fee Related
- 2003-06-19 EP EP03760968A patent/EP1513419A2/en not_active Ceased
- 2003-06-19 AU AU2003247225A patent/AU2003247225A1/en not_active Abandoned
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BRPI0311909A8 (pt) | 2018-02-06 |
AU2003247225A1 (en) | 2004-01-06 |
AU2003247225A8 (en) | 2004-01-06 |
EP2283835A2 (en) | 2011-02-16 |
EP3184107A1 (en) | 2017-06-28 |
CN100469361C (zh) | 2009-03-18 |
EP1513419A2 (en) | 2005-03-16 |
PL375076A1 (en) | 2005-11-14 |
JP2005529980A (ja) | 2005-10-06 |
CN1674795A (zh) | 2005-09-28 |
WO2004000042A3 (en) | 2004-05-06 |
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