BR0309030A - Métodos para prevenir, tratar ou controlar uma doença ou condição corpórea, para reduzir o colesterol em tecido periférico ao mesmo tempo que reduz ou evita os efeitos adversos associados com a tarapia de lipossoma, para prevenir ou tratar uma doença ou distúrbio associado (a) com os nìveis de colesterol anormais, e para reduzir o colesterol em um ser humano doente - Google Patents

Métodos para prevenir, tratar ou controlar uma doença ou condição corpórea, para reduzir o colesterol em tecido periférico ao mesmo tempo que reduz ou evita os efeitos adversos associados com a tarapia de lipossoma, para prevenir ou tratar uma doença ou distúrbio associado (a) com os nìveis de colesterol anormais, e para reduzir o colesterol em um ser humano doente

Info

Publication number
BR0309030A
BR0309030A BR0309030-2A BR0309030A BR0309030A BR 0309030 A BR0309030 A BR 0309030A BR 0309030 A BR0309030 A BR 0309030A BR 0309030 A BR0309030 A BR 0309030A
Authority
BR
Brazil
Prior art keywords
treat
prevent
disease
cholesterol
methods
Prior art date
Application number
BR0309030-2A
Other languages
English (en)
Inventor
Wendi V Rodriqueza
Charles L Bisgaier
Original Assignee
Esperion Luv Dev Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esperion Luv Dev Inc filed Critical Esperion Luv Dev Inc
Publication of BR0309030A publication Critical patent/BR0309030A/pt

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Preparation (AREA)

Abstract

"MéTODOS PARA PREVENIR, TRATAR OU CONTROLAR UMA DOENçA OU CONDIçãO CORPóREA, PARA REDUZIR O COLESTEROL EM TECIDO PERIFéRICO AO MESMO TEMPO QUE REDUZ OU EVITA OS EFEITOS ADVERSOS ASSOCIADOS COM A TERAPIA DE LIPOSSOMA, PARA PREVENIR OU TRATAR UMA DOENçA OU DISTúRBIO ASSOCIADO(A) COM OS NìVEIS DE COLESTEROL ANORMAIS, E PARA REDUZIR O COLESTEROL EM UM SER HUMANO DOENTE". A presente invenção diz respeito às formulações farmacêuticas que compreendem lipossomas e aos métodos para usar tais lipossomas para prevenir, tratar ou controlar uma variedade de doenças e/ou condições corpóreas. Os lipossomas podem compreender vesículas unilamelares grandes (LUVs) sozinhas ou em combinação com vesículas multilamelares (MLVs), vesículas unilamelares pequenas (SUVs) ou outros produtos terapêuticos. A invenção diz respeito aos lipossomas tendo certos diâmetros administrados aos pacientes usando doses específicas e/ou regimes de dosagem.
BR0309030-2A 2002-04-05 2003-04-04 Métodos para prevenir, tratar ou controlar uma doença ou condição corpórea, para reduzir o colesterol em tecido periférico ao mesmo tempo que reduz ou evita os efeitos adversos associados com a tarapia de lipossoma, para prevenir ou tratar uma doença ou distúrbio associado (a) com os nìveis de colesterol anormais, e para reduzir o colesterol em um ser humano doente BR0309030A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37040902P 2002-04-05 2002-04-05
PCT/US2003/010339 WO2003086351A1 (en) 2002-04-05 2003-04-04 Compositions and methods for dosing liposomes of certain sizes to treat or prevent disease

Publications (1)

Publication Number Publication Date
BR0309030A true BR0309030A (pt) 2005-02-01

Family

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BR0309030-2A BR0309030A (pt) 2002-04-05 2003-04-04 Métodos para prevenir, tratar ou controlar uma doença ou condição corpórea, para reduzir o colesterol em tecido periférico ao mesmo tempo que reduz ou evita os efeitos adversos associados com a tarapia de lipossoma, para prevenir ou tratar uma doença ou distúrbio associado (a) com os nìveis de colesterol anormais, e para reduzir o colesterol em um ser humano doente

Country Status (26)

Country Link
US (2) US20040009216A1 (pt)
EP (1) EP1501482A1 (pt)
JP (1) JP2005527582A (pt)
KR (1) KR20050009988A (pt)
CN (1) CN1655764A (pt)
AP (1) AP2004003157A0 (pt)
AU (1) AU2003230800A1 (pt)
BR (1) BR0309030A (pt)
CA (1) CA2480763A1 (pt)
CR (1) CR7563A (pt)
EA (1) EA007986B1 (pt)
EC (1) ECSP045409A (pt)
HR (1) HRP20040915A2 (pt)
IL (1) IL164370A0 (pt)
IS (1) IS7493A (pt)
MA (1) MA27298A1 (pt)
MX (1) MXPA04009692A (pt)
NO (1) NO20044751L (pt)
NZ (1) NZ535900A (pt)
OA (1) OA12799A (pt)
PL (1) PL372689A1 (pt)
RS (1) RS87704A (pt)
TN (1) TNSN04190A1 (pt)
UA (1) UA80121C2 (pt)
WO (1) WO2003086351A1 (pt)
ZA (1) ZA200407947B (pt)

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OA12799A (en) 2006-07-11
WO2003086351A1 (en) 2003-10-23
JP2005527582A (ja) 2005-09-15
EA007986B1 (ru) 2007-02-27
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NZ535900A (en) 2008-08-29
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IS7493A (is) 2004-10-08
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CN1655764A (zh) 2005-08-17
US20040009216A1 (en) 2004-01-15
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US20080213351A1 (en) 2008-09-04
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