BR0308856A - Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite c - Google Patents
Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite cInfo
- Publication number
- BR0308856A BR0308856A BR0308856-1A BR0308856A BR0308856A BR 0308856 A BR0308856 A BR 0308856A BR 0308856 A BR0308856 A BR 0308856A BR 0308856 A BR0308856 A BR 0308856A
- Authority
- BR
- Brazil
- Prior art keywords
- hepatitis
- inhibitors
- piranon
- pirandion
- virus
- Prior art date
Links
- 241000711549 Hepacivirus C Species 0.000 title abstract 4
- 108060004795 Methyltransferase Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36938102P | 2002-04-01 | 2002-04-01 | |
| PCT/IB2003/001206 WO2003082848A1 (en) | 2002-04-01 | 2003-03-21 | Pyranon and pyrandion inhibitors of hepatitis c virus rna-dependent rna polymerase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0308856A true BR0308856A (pt) | 2005-02-22 |
Family
ID=28675577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0308856-1A BR0308856A (pt) | 2002-04-01 | 2003-03-21 | Piranon e pirandion inibidores do rna polimerase dependente do rna do vìrus da hepatite c |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6878727B2 (enExample) |
| EP (1) | EP1490350B1 (enExample) |
| JP (1) | JP2005526102A (enExample) |
| AT (1) | ATE337309T1 (enExample) |
| AU (1) | AU2003215826A1 (enExample) |
| BR (1) | BR0308856A (enExample) |
| CA (1) | CA2480583C (enExample) |
| DE (1) | DE60307804T2 (enExample) |
| ES (1) | ES2268394T3 (enExample) |
| MX (1) | MXPA04009672A (enExample) |
| WO (1) | WO2003082848A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DOP2003000641A (es) * | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
| US7148226B2 (en) * | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
| IN2012DN04853A (enExample) | 2004-02-20 | 2015-09-25 | Boehringer Ingelheim Int | |
| US7115749B2 (en) | 2004-10-29 | 2006-10-03 | Schering Corporation | Substituted 5-oxo pyrazoles and [1,2,4]triazoles as antiviral agents |
| EP1881828A4 (en) * | 2005-05-20 | 2009-06-03 | Valeant Res & Dev | TREATMENT OF HEPATITIS C (HCV) USING SUB-THERAPEUTIC DOSES OF RIBAVIRIN |
| US7816348B2 (en) * | 2006-02-03 | 2010-10-19 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| WO2008047694A1 (fr) * | 2006-10-13 | 2008-04-24 | Aska Pharmaceutical Co., Ltd. | Procédé de fabrication d'un composé benzothiazole |
| EP2494991A1 (en) | 2007-05-04 | 2012-09-05 | Vertex Pharmaceuticals Incorporated | Combination therapy for the treatment of HCV infection |
| CA2693495A1 (en) * | 2007-08-03 | 2009-02-12 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| EP2188274A4 (en) * | 2007-08-03 | 2011-05-25 | Boehringer Ingelheim Int | VIRAL POLYMERASE HEMMER |
| EA201000948A1 (ru) | 2007-12-19 | 2011-02-28 | Бёрингер Ингельхайм Интернациональ Гмбх | Ингибиторы вирусной полимеразы |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1140049A (en) * | 1977-12-22 | 1983-01-25 | Dke J.E. Helgstran | Pharmaceutical preparations from derivatives of hydroxycarbonylphosphonic acid |
| US6174868B1 (en) * | 1992-09-10 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
| US5846964A (en) * | 1993-07-19 | 1998-12-08 | Tokyo Tanabe Company Limited | Hepatitis C virus proliferation inhibitor |
| IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
| AU777040B2 (en) * | 1999-02-22 | 2004-09-30 | Shire Biochem Inc. | (1,8) naphthyridine derivatives having antiviral activity |
| AR034127A1 (es) * | 2000-07-21 | 2004-02-04 | Schering Corp | Imidazolidinonas como inhibidores de ns3-serina proteasa del virus de hepatitis c, composicion farmaceutica, un metodo para su preparacion, y el uso de las mismas para la manufactura de un medicamento |
-
2003
- 2003-03-21 AU AU2003215826A patent/AU2003215826A1/en not_active Abandoned
- 2003-03-21 EP EP03745205A patent/EP1490350B1/en not_active Expired - Lifetime
- 2003-03-21 BR BR0308856-1A patent/BR0308856A/pt not_active IP Right Cessation
- 2003-03-21 DE DE60307804T patent/DE60307804T2/de not_active Expired - Fee Related
- 2003-03-21 WO PCT/IB2003/001206 patent/WO2003082848A1/en not_active Ceased
- 2003-03-21 CA CA002480583A patent/CA2480583C/en not_active Expired - Fee Related
- 2003-03-21 AT AT03745205T patent/ATE337309T1/de not_active IP Right Cessation
- 2003-03-21 JP JP2003580314A patent/JP2005526102A/ja not_active Abandoned
- 2003-03-21 MX MXPA04009672A patent/MXPA04009672A/es active IP Right Grant
- 2003-03-21 ES ES03745205T patent/ES2268394T3/es not_active Expired - Lifetime
- 2003-03-31 US US10/403,537 patent/US6878727B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2480583A1 (en) | 2003-10-09 |
| EP1490350A1 (en) | 2004-12-29 |
| AU2003215826A1 (en) | 2003-10-13 |
| WO2003082848A1 (en) | 2003-10-09 |
| ES2268394T3 (es) | 2007-03-16 |
| MXPA04009672A (es) | 2004-11-12 |
| DE60307804D1 (de) | 2006-10-05 |
| ATE337309T1 (de) | 2006-09-15 |
| US6878727B2 (en) | 2005-04-12 |
| CA2480583C (en) | 2008-07-15 |
| JP2005526102A (ja) | 2005-09-02 |
| EP1490350B1 (en) | 2006-08-23 |
| DE60307804T2 (de) | 2007-01-18 |
| US20030195239A1 (en) | 2003-10-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A E 7A ANUIDADES |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010. |