ATE337309T1 - Pyranon- und pyrandioninhibitoren der rna- abhängigen rna-polymerase des hepatitis-c-virus - Google Patents
Pyranon- und pyrandioninhibitoren der rna- abhängigen rna-polymerase des hepatitis-c-virusInfo
- Publication number
- ATE337309T1 ATE337309T1 AT03745205T AT03745205T ATE337309T1 AT E337309 T1 ATE337309 T1 AT E337309T1 AT 03745205 T AT03745205 T AT 03745205T AT 03745205 T AT03745205 T AT 03745205T AT E337309 T1 ATE337309 T1 AT E337309T1
- Authority
- AT
- Austria
- Prior art keywords
- hepatitis
- virus
- inhibitors
- rna
- pyrandione
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36938102P | 2002-04-01 | 2002-04-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE337309T1 true ATE337309T1 (de) | 2006-09-15 |
Family
ID=28675577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03745205T ATE337309T1 (de) | 2002-04-01 | 2003-03-21 | Pyranon- und pyrandioninhibitoren der rna- abhängigen rna-polymerase des hepatitis-c-virus |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6878727B2 (de) |
| EP (1) | EP1490350B1 (de) |
| JP (1) | JP2005526102A (de) |
| AT (1) | ATE337309T1 (de) |
| AU (1) | AU2003215826A1 (de) |
| BR (1) | BR0308856A (de) |
| CA (1) | CA2480583C (de) |
| DE (1) | DE60307804T2 (de) |
| ES (1) | ES2268394T3 (de) |
| MX (1) | MXPA04009672A (de) |
| WO (1) | WO2003082848A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DOP2003000641A (es) * | 2002-05-10 | 2003-11-15 | Pfizer | Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan |
| US7148226B2 (en) * | 2003-02-21 | 2006-12-12 | Agouron Pharmaceuticals, Inc. | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same |
| HRP20130971T1 (hr) | 2004-02-20 | 2013-11-08 | Boehringer Ingelheim International Gmbh | Inhibitori virusne polimeraze |
| JP4663733B2 (ja) * | 2004-10-29 | 2011-04-06 | シェーリング コーポレイション | 抗ウイルス物質としての置換５−オキソピラゾールおよび置換［１，２，４］トリアゾール |
| WO2006127289A1 (en) * | 2005-05-20 | 2006-11-30 | Valeant Research & Development | Treatment of hcv with subtherapeutic doses of ribavirin |
| US7816348B2 (en) * | 2006-02-03 | 2010-10-19 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| JP5244604B2 (ja) * | 2006-10-13 | 2013-07-24 | あすか製薬株式会社 | ベンゾチアゾール化合物の製造方法 |
| ES2381410T3 (es) | 2007-05-04 | 2012-05-28 | Vertex Pharmceuticals Incorporated | Terapia de combinación paa el tratamiento de infecciones por VHC |
| US8242140B2 (en) * | 2007-08-03 | 2012-08-14 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
| JP2010535155A (ja) * | 2007-08-03 | 2010-11-18 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | ウイルスポリメラーゼ阻害剤 |
| EP2234977A4 (de) | 2007-12-19 | 2011-04-13 | Boehringer Ingelheim Int | Viren-polymerasehemmer |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1144937A (en) | 1977-12-22 | 1983-04-19 | Dke J.E. Helgstrand | Aromatic derivatives, pharmaceutical compositions and methods for combatting virus infections |
| US6174868B1 (en) | 1992-09-10 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
| WO1995003056A1 (en) | 1993-07-19 | 1995-02-02 | Tokyo Tanabe Company Limited | Hepatitis c virus proliferation inhibitor |
| IL129871A (en) * | 1994-05-06 | 2003-11-23 | Pharmacia & Upjohn Inc | Process for preparing 4-phenyl-substituted octanoyl-oxazolidin-2-one intermediates that are useful for preparing pyran-2-ones useful for treating retroviral infections |
| AU777040B2 (en) * | 1999-02-22 | 2004-09-30 | Shire Biochem Inc. | (1,8) naphthyridine derivatives having antiviral activity |
| AR034127A1 (es) * | 2000-07-21 | 2004-02-04 | Schering Corp | Imidazolidinonas como inhibidores de ns3-serina proteasa del virus de hepatitis c, composicion farmaceutica, un metodo para su preparacion, y el uso de las mismas para la manufactura de un medicamento |
-
2003
- 2003-03-21 AT AT03745205T patent/ATE337309T1/de not_active IP Right Cessation
- 2003-03-21 MX MXPA04009672A patent/MXPA04009672A/es active IP Right Grant
- 2003-03-21 AU AU2003215826A patent/AU2003215826A1/en not_active Abandoned
- 2003-03-21 BR BR0308856-1A patent/BR0308856A/pt not_active IP Right Cessation
- 2003-03-21 WO PCT/IB2003/001206 patent/WO2003082848A1/en not_active Ceased
- 2003-03-21 CA CA002480583A patent/CA2480583C/en not_active Expired - Fee Related
- 2003-03-21 JP JP2003580314A patent/JP2005526102A/ja not_active Abandoned
- 2003-03-21 DE DE60307804T patent/DE60307804T2/de not_active Expired - Fee Related
- 2003-03-21 EP EP03745205A patent/EP1490350B1/de not_active Expired - Lifetime
- 2003-03-21 ES ES03745205T patent/ES2268394T3/es not_active Expired - Lifetime
- 2003-03-31 US US10/403,537 patent/US6878727B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| ES2268394T3 (es) | 2007-03-16 |
| MXPA04009672A (es) | 2004-11-12 |
| DE60307804T2 (de) | 2007-01-18 |
| EP1490350A1 (de) | 2004-12-29 |
| CA2480583A1 (en) | 2003-10-09 |
| US6878727B2 (en) | 2005-04-12 |
| JP2005526102A (ja) | 2005-09-02 |
| AU2003215826A1 (en) | 2003-10-13 |
| BR0308856A (pt) | 2005-02-22 |
| CA2480583C (en) | 2008-07-15 |
| US20030195239A1 (en) | 2003-10-16 |
| EP1490350B1 (de) | 2006-08-23 |
| WO2003082848A1 (en) | 2003-10-09 |
| DE60307804D1 (de) | 2006-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |