BR0307595A - Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico - Google Patents

Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico

Info

Publication number
BR0307595A
BR0307595A BR0307595-8A BR0307595A BR0307595A BR 0307595 A BR0307595 A BR 0307595A BR 0307595 A BR0307595 A BR 0307595A BR 0307595 A BR0307595 A BR 0307595A
Authority
BR
Brazil
Prior art keywords
sildenafil
treatment
pde5 inhibitors
polycystic ovarian
ovarian syndrome
Prior art date
Application number
BR0307595-8A
Other languages
English (en)
Inventor
Mahmoud Nizar Ghazzi
Nandan Parmanand Koppiker
Simon Lempriere Westbrook
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of BR0307595A publication Critical patent/BR0307595A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

"USO DE INIBIDORES DE PDE5 TAL COMO SILDENAFIL NO TRATAMENTO DE SìNDROME DE OVáRIO POLICìSTICO". A presente invenção refere-se ao uso de um inibidor de PDE5 de pirazolopirimidinona tal como sildenafil para o tratamento de síndrome do ovário policístico.
BR0307595-8A 2002-02-07 2003-01-27 Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico BR0307595A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35503802P 2002-02-07 2002-02-07
PCT/IB2003/000257 WO2003066061A1 (en) 2002-02-07 2003-01-27 Use of pde5 inhibitors such as sildenafil in the treatment of polycystic ovary syndrome

Publications (1)

Publication Number Publication Date
BR0307595A true BR0307595A (pt) 2005-02-01

Family

ID=27734455

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0307595-8A BR0307595A (pt) 2002-02-07 2003-01-27 Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico

Country Status (9)

Country Link
US (1) US20040029891A1 (pt)
EP (1) EP1471917A1 (pt)
JP (1) JP2005519927A (pt)
AU (1) AU2003205926A1 (pt)
BR (1) BR0307595A (pt)
CA (1) CA2475377A1 (pt)
MX (1) MXPA04007713A (pt)
TW (1) TW200303747A (pt)
WO (1) WO2003066061A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7105489B2 (en) * 2002-01-22 2006-09-12 Amylin Pharmaceuticals, Inc. Methods and compositions for treating polycystic ovary syndrome
EP1581247A4 (en) * 2002-12-11 2007-09-12 Amylin Pharmaceuticals Inc METHODS AND COMPOSITIONS FOR TREATING STEIN-LEVENTHAL SYNDROME
BRPI0409229A (pt) * 2003-04-01 2006-03-28 Applied Research Systems inibidores das fosfodiesterases na infertilidade
TW200530246A (en) * 2003-12-19 2005-09-16 Bristol Myers Squibb Co Azabicyclic heterocycles as cannabinoid receptor modulators
CA2550375A1 (en) * 2003-12-19 2005-07-14 Bristol-Myers Squibb Company Azabicyclic heterocycles as cannabinoid receptor modulators
AU2006204334B2 (en) * 2005-01-10 2012-02-23 Cortendo Ab (Publ) Methods and compositions for treating diabetes, metabolic syndrome and other conditions
EP1956906A4 (en) 2005-11-09 2009-12-30 Combinatorx Inc METHODS, COMPOSITIONS AND KITS FOR THE TREATMENT OF PATHOLOGIES
WO2007081980A2 (en) * 2006-01-10 2007-07-19 Diobex, Inc. Methods and compositions for treating prostate cancer
JP4975805B2 (ja) * 2006-04-04 2012-07-11 ドン・ア・ファーム・カンパニー・リミテッド ピラゾロピリミジノン化合物を有効成分として含む、前立腺肥大症予防及び治療剤
AU2007303219A1 (en) * 2006-10-02 2008-04-10 Cortendo Ab (Publ) Ketoconazole enantiomer in humans
AU2008267274A1 (en) * 2007-06-26 2008-12-31 Solvay Pharmaceuticals B.V. Sildenafil N-oxide as prodrug
ES2344183B1 (es) * 2009-02-18 2011-06-10 Italfarmaco, S.A. Uso de agentes sensibilizantes a insulina por via vaginal.
CA2789900A1 (en) * 2010-03-22 2011-09-29 Glenmark Pharmaceuticals S.A. Pharmaceutical composition comprising a pyrimidineone derivative
AT512084A1 (de) 2011-10-20 2013-05-15 Univ Wien Tech Diazabicyclo- und diazaspiro-alkanderivate als phosphodiesterase-5 inhibitoren
CN106442764B (zh) * 2016-08-31 2019-01-22 王义明 多囊卵巢综合征的诊断和/或分型标志物及制备试剂的用途
US11376263B2 (en) * 2020-10-08 2022-07-05 Fortress Biotech, Inc. Cyproterone acetate compositions and uses thereof
DE202022104150U1 (de) 2022-07-22 2022-08-11 Malti Arya Eine polypharmazeutische Formulierung als potenzielles Mittel zur Behandlung des polyzystischen Ovarsyndroms

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242474B1 (en) * 1997-06-27 2001-06-05 Fujisawa Pharmaceutical Co., Ltd. Aromatic ring derivatives
EP1132087A4 (en) * 1998-11-13 2002-06-26 Fujisawa Pharmaceutical Co MEDICINE AGAINST POLYCYSTIC OVARY SYNDROME
JP2004506009A (ja) * 2000-08-11 2004-02-26 ファイザー・インク インスリン抵抗性症候群の治療
US6548508B2 (en) * 2000-10-20 2003-04-15 Pfizer, Inc. Use of PDE V inhibitors for improved fecundity in mammals

Also Published As

Publication number Publication date
JP2005519927A (ja) 2005-07-07
AU2003205926A1 (en) 2003-09-02
CA2475377A1 (en) 2003-08-14
US20040029891A1 (en) 2004-02-12
TW200303747A (en) 2003-09-16
MXPA04007713A (es) 2004-11-10
EP1471917A1 (en) 2004-11-03
WO2003066061A1 (en) 2003-08-14

Similar Documents

Publication Publication Date Title
BR0307595A (pt) Uso de inibidores de pde5 tal como sildenafil no tratamento de sìndrome de ovário policìstico
IL163781A0 (en) Purine derivatives as kinase inhibitors
MXPA04008613A (es) N-aminoacetil-pirrolidina-2-carbonitrilos y su uso como inhibidores de ddp-iv.
TW200720271A (en) DNA-PK inhibitors
DK1893587T3 (da) Fremgangsmåde til fremstilling af dihydroquinazoliner
GEP20105081B (en) Pyrrolotriazine compounds as kinase inhibitors
ATE365740T1 (de) Substituierte pyrazolopyrimidine
DE602005014382D1 (de) 2-pyrimidinyl-pyrazolopyridin-erbb-kinaseinhibitoren
TW200716183A (en) Parakeratosis inhibitor, pore-contracting agent and external composition for skin
NO20071077L (no) Fosfonatanaloger til HIV-inhibitorforbindelser
HK1079522A1 (en) Thienyl compounds
WO2007120333A3 (en) Tetracyclic kinase inhibitors
GT200300231A (es) Inhibidores de hiv-integrasa, composiciones farmaceuticas y metodos para su uso
TNSN06260A1 (en) Process for the preparation of tryptase inhibitors
UY27203A1 (es) Bencimidazoles útiles en el tratamiento de la disfunción sexual
BG108245A (en) Compositions containing imidazotriazinone for nasal application
HK1096548A1 (en) Imidazopyridine-derivatives as inductible no-synthase inhibitors
MXPA06003345A (es) Derivados de aminopiridina como inhibidores de la no-sintasa inducible.
MX2007001952A (es) Compuestos y composiciones utiles como inhibidores de catepsina-s.
EP1605926A4 (en) USE OF PINITOL OR CHIROINOSITOL FOR THE PROTECTION OF THE LIVER
ATE396177T1 (de) Neue kristalline formen eines faktor xa inhibitors
BRPI0417263A (pt) imidazopiridinas para uso como inibidores de secreção gástrica
LT2003075A (en) Inhibitor of monoamine uptake
WO2004042114A3 (en) White rust corrosion inhibitors
WO2002083108A3 (de) Zusammensetzungen enthaltend cgmp-pde-inhibitoren und lokalanästhetika zur nasalen applikation

Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE 5A., 6A., E 7A. ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2051 DE 27/04/2010.