BR0213288A - Etilcelulose altamente compressìvel para formação de comprimidos - Google Patents
Etilcelulose altamente compressìvel para formação de comprimidosInfo
- Publication number
- BR0213288A BR0213288A BR0213288-5A BR0213288A BR0213288A BR 0213288 A BR0213288 A BR 0213288A BR 0213288 A BR0213288 A BR 0213288A BR 0213288 A BR0213288 A BR 0213288A
- Authority
- BR
- Brazil
- Prior art keywords
- highly compressible
- ethylcellulose
- tableting
- dosage form
- tablets
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Anesthesiology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Nutrition Science (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- AIDS & HIV (AREA)
Abstract
"ETILCELULOSE ALTAMENTE COMPRESSìVEL PARA FORMAçãO DE COMPRIMIDOS". A presente invenção refere-se a uma composição de forma de dosagem farmacêutica que é composta de uma etilcelulose que tem um limite inferior da faixa de etoxila de 49,6%, uma viscosidade menor do que 53 cps e pelo menos um ingrediente farmaceuticamente ativo. Esta forma de dosagem é altamente compressível e compactável formando comprimidos ou péletes mais duros com melhor retardamento na liberação do que os comprimidos comparáveis da técnica anterior.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/977,785 US6592901B2 (en) | 2001-10-15 | 2001-10-15 | Highly compressible ethylcellulose for tableting |
PCT/US2002/032049 WO2003032955A1 (en) | 2001-10-15 | 2002-10-08 | Highly compressible ethylcellulose for tableting |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0213288A true BR0213288A (pt) | 2004-11-23 |
Family
ID=25525513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0213288-5A BR0213288A (pt) | 2001-10-15 | 2002-10-08 | Etilcelulose altamente compressìvel para formação de comprimidos |
Country Status (12)
Country | Link |
---|---|
US (1) | US6592901B2 (pt) |
EP (1) | EP1435918B1 (pt) |
JP (1) | JP4672981B2 (pt) |
KR (1) | KR20050034612A (pt) |
CN (1) | CN100482280C (pt) |
BR (1) | BR0213288A (pt) |
CA (1) | CA2463583C (pt) |
DE (1) | DE60232898D1 (pt) |
ES (1) | ES2325986T3 (pt) |
MX (1) | MXPA04003378A (pt) |
RU (1) | RU2396072C2 (pt) |
WO (1) | WO2003032955A1 (pt) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
DE102004032051A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
PE20050728A1 (es) * | 2003-08-06 | 2005-11-10 | Gruenenthal Chemie | Forma de dosificacion a prueba de abuso |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
PL1750862T3 (pl) | 2004-06-04 | 2011-06-30 | Teva Pharma | Kompozycja farmaceutyczna zawierająca irbesartan |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
US20060068009A1 (en) * | 2004-09-30 | 2006-03-30 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20070077297A1 (en) * | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
BRPI0518396A2 (pt) * | 2004-12-27 | 2008-11-18 | Eisai R&D Man Co Ltd | mÉtodo para estabilizaÇço de droga anti-demÊncia |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
FR2898056B1 (fr) | 2006-03-01 | 2012-01-20 | Ethypharm Sa | Comprimes resistant a l'ecrasement destines a eviter le detournement illicite |
US7749537B2 (en) * | 2006-12-04 | 2010-07-06 | Scolr Pharma, Inc. | Method of forming a tablet |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
WO2008135855A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and a nonionizable polymer |
WO2008135828A2 (en) | 2007-05-03 | 2008-11-13 | Pfizer Products Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
WO2008140772A2 (en) * | 2007-05-08 | 2008-11-20 | Hercules Incorporated | Robust rapid disintegration tablet formulation |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
WO2008149192A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
WO2009073215A1 (en) | 2007-12-06 | 2009-06-11 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
EP2240162A4 (en) | 2007-12-06 | 2013-10-09 | Bend Res Inc | NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER |
JP5774853B2 (ja) | 2008-01-25 | 2015-09-09 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 医薬投薬形 |
TWI524904B (zh) | 2008-05-09 | 2016-03-11 | 歌林達股份有限公司 | 製備醫藥用固體劑型,尤指錠劑之方法,及製備固體劑型,尤指錠劑之前驅物之方法 |
WO2009157564A1 (ja) * | 2008-06-26 | 2009-12-30 | 旭化成ケミカルズ株式会社 | セルロース組成物 |
US20100260842A1 (en) * | 2009-04-06 | 2010-10-14 | Rashmi Nair | Pseudoephedrine pharmaceutical formulations |
JP2012533586A (ja) | 2009-07-22 | 2012-12-27 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 酸化安定化された不正使用防止剤形 |
CA2765971C (en) | 2009-07-22 | 2017-08-22 | Gruenenthal Gmbh | Hot-melt extruded controlled release dosage form |
US8901113B2 (en) | 2009-09-30 | 2014-12-02 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
ES2606227T3 (es) | 2010-02-03 | 2017-03-23 | Grünenthal GmbH | Preparación de una composición farmacéutica en polvo mediante una extrusora |
NZ608865A (en) | 2010-09-02 | 2015-03-27 | Gruenenthal Chemie | Tamper resistant dosage form comprising an anionic polymer |
AU2011297901B2 (en) | 2010-09-02 | 2014-07-31 | Grunenthal Gmbh | Tamper resistant dosage form comprising inorganic salt |
TWI535461B (zh) | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
PT2736497T (pt) | 2011-07-29 | 2017-11-30 | Gruenenthal Gmbh | Comprimido resistente a adulteração proporcionando libertação imediata de fármaco |
CN103841964A (zh) | 2011-07-29 | 2014-06-04 | 格吕伦塔尔有限公司 | 提供药物立即释放的抗破碎片剂 |
JP6117249B2 (ja) | 2012-02-28 | 2017-04-19 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 薬理学的に活性な化合物および陰イオン性ポリマーを含むタンパーレジスタント剤形 |
WO2013156453A1 (en) | 2012-04-18 | 2013-10-24 | Grünenthal GmbH | Tamper resistant and dose-dumping resistant pharmaceutical dosage form |
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-
2001
- 2001-10-15 US US09/977,785 patent/US6592901B2/en not_active Expired - Lifetime
-
2002
- 2002-10-08 CN CNB028204050A patent/CN100482280C/zh not_active Expired - Fee Related
- 2002-10-08 KR KR1020047005473A patent/KR20050034612A/ko not_active Application Discontinuation
- 2002-10-08 RU RU2004115021/15A patent/RU2396072C2/ru not_active IP Right Cessation
- 2002-10-08 WO PCT/US2002/032049 patent/WO2003032955A1/en active Application Filing
- 2002-10-08 DE DE60232898T patent/DE60232898D1/de not_active Expired - Lifetime
- 2002-10-08 EP EP02776176A patent/EP1435918B1/en not_active Expired - Fee Related
- 2002-10-08 ES ES02776176T patent/ES2325986T3/es not_active Expired - Lifetime
- 2002-10-08 MX MXPA04003378A patent/MXPA04003378A/es active IP Right Grant
- 2002-10-08 CA CA002463583A patent/CA2463583C/en not_active Expired - Fee Related
- 2002-10-08 JP JP2003535759A patent/JP4672981B2/ja not_active Expired - Fee Related
- 2002-10-08 BR BR0213288-5A patent/BR0213288A/pt not_active Application Discontinuation
Also Published As
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RU2396072C2 (ru) | 2010-08-10 |
WO2003032955A1 (en) | 2003-04-24 |
ES2325986T3 (es) | 2009-09-28 |
CA2463583A1 (en) | 2003-04-24 |
MXPA04003378A (es) | 2004-06-18 |
US6592901B2 (en) | 2003-07-15 |
CN100482280C (zh) | 2009-04-29 |
JP2005509620A (ja) | 2005-04-14 |
DE60232898D1 (de) | 2009-08-20 |
EP1435918A1 (en) | 2004-07-14 |
KR20050034612A (ko) | 2005-04-14 |
CN1571662A (zh) | 2005-01-26 |
JP4672981B2 (ja) | 2011-04-20 |
US20030077327A1 (en) | 2003-04-24 |
EP1435918B1 (en) | 2009-07-08 |
CA2463583C (en) | 2009-09-15 |
RU2004115021A (ru) | 2005-04-20 |
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