BR0213177A - Derivados de 5-metóxi-8-aril-[1,2,4]triazolo[1,5-a]piridina - Google Patents
Derivados de 5-metóxi-8-aril-[1,2,4]triazolo[1,5-a]piridinaInfo
- Publication number
- BR0213177A BR0213177A BR0213177-3A BR0213177A BR0213177A BR 0213177 A BR0213177 A BR 0213177A BR 0213177 A BR0213177 A BR 0213177A BR 0213177 A BR0213177 A BR 0213177A
- Authority
- BR
- Brazil
- Prior art keywords
- methoxy
- aryl
- pyridine derivatives
- halogen
- substituted
- Prior art date
Links
- 229910052736 halogen Inorganic materials 0.000 abstract 3
- 150000002367 halogens Chemical group 0.000 abstract 3
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 102000000506 Adenosine A2 Receptors Human genes 0.000 abstract 1
- 108010041368 Adenosine A2 Receptors Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- LENLQGBLVGGAMF-UHFFFAOYSA-N tributyl([1,2,4]triazolo[1,5-a]pyridin-6-yl)stannane Chemical class C1=C([Sn](CCCC)(CCCC)CCCC)C=CC2=NC=NN21 LENLQGBLVGGAMF-UHFFFAOYSA-N 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Anesthesiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01123949 | 2001-10-08 | ||
| PCT/EP2002/010917 WO2003031445A1 (en) | 2001-10-08 | 2002-09-28 | 5-methoxy-8-aryl-[1,2,4] triazolo [1,5-a] pyridine derivatives as adenosine receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0213177A true BR0213177A (pt) | 2004-09-14 |
Family
ID=8178877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0213177-3A BR0213177A (pt) | 2001-10-08 | 2002-09-28 | Derivados de 5-metóxi-8-aril-[1,2,4]triazolo[1,5-a]piridina |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6693116B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1436292B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4101756B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100604407B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1254475C (cg-RX-API-DMAC7.html) |
| AR (1) | AR036735A1 (cg-RX-API-DMAC7.html) |
| AT (1) | ATE338043T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2002338827B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0213177A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2462801A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60214408T2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2269772T3 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA04003278A (cg-RX-API-DMAC7.html) |
| PL (1) | PL370565A1 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2298009C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2003031445A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1830978B (zh) * | 2005-03-07 | 2010-06-16 | 中国人民解放军军事医学科学院毒物药物研究所 | 吡唑并[4,3-c]喹啉-3-酮化合物、其制备方法及其应用 |
| WO2009017954A1 (en) * | 2007-08-01 | 2009-02-05 | Phenomix Corporation | Inhibitors of jak2 kinase |
| GB0719803D0 (en) * | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| CN102131390A (zh) | 2008-06-20 | 2011-07-20 | 健泰科生物技术公司 | 三唑并吡啶jak抑制剂化合物和方法 |
| JP5512665B2 (ja) | 2008-06-20 | 2014-06-04 | ジェネンテック， インコーポレイテッド | トリアゾロピリジンｊａｋ阻害剤化合物と方法 |
| HRP20160488T1 (hr) * | 2008-12-19 | 2016-06-17 | Leo Pharma A/S | Triazolopiridini kao inhibitori fosfodiesteraze za liječenje kožnih bolesti |
| NZ597140A (en) | 2009-06-05 | 2014-01-31 | Cephalon Inc | Preparation and uses of 1,2,4-triazolo [1,5a] pyridine derivatives |
| UA112096C2 (uk) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | Заміщені триазолопіридини та їх застосування як інгібіторів ttk |
| CA2878792A1 (en) * | 2012-07-12 | 2014-01-16 | Chiesi Farmaceutici S.P.A. | Inhibition of enzymes |
| EP2895487B1 (en) * | 2012-09-14 | 2018-08-15 | Dow AgroSciences LLC | An improved process for the preparation of 2-amino-5,8-dimethoxy[1,2,4]triazolo[1,5-c]pyrimidine from 4-amino-2,5-dimethoxypyrimidine |
| CA2922770A1 (en) | 2013-09-05 | 2015-03-12 | F. Hoffmann-La Roche Ag | Triazolopyridine compounds, compositions and methods of use thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE287262C (cg-RX-API-DMAC7.html) * | ||||
| US6355653B1 (en) | 1999-09-06 | 2002-03-12 | Hoffmann-La Roche Inc. | Amino-triazolopyridine derivatives |
| US6514989B1 (en) * | 2001-07-20 | 2003-02-04 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives |
-
2002
- 2002-09-18 US US10/246,551 patent/US6693116B2/en not_active Expired - Fee Related
- 2002-09-28 CA CA002462801A patent/CA2462801A1/en not_active Abandoned
- 2002-09-28 EP EP02777254A patent/EP1436292B1/en not_active Expired - Lifetime
- 2002-09-28 AU AU2002338827A patent/AU2002338827B2/en not_active Ceased
- 2002-09-28 RU RU2004114277/04A patent/RU2298009C2/ru not_active IP Right Cessation
- 2002-09-28 KR KR1020047005097A patent/KR100604407B1/ko not_active Expired - Fee Related
- 2002-09-28 DE DE60214408T patent/DE60214408T2/de not_active Expired - Fee Related
- 2002-09-28 AT AT02777254T patent/ATE338043T1/de not_active IP Right Cessation
- 2002-09-28 BR BR0213177-3A patent/BR0213177A/pt not_active IP Right Cessation
- 2002-09-28 WO PCT/EP2002/010917 patent/WO2003031445A1/en not_active Ceased
- 2002-09-28 MX MXPA04003278A patent/MXPA04003278A/es active IP Right Grant
- 2002-09-28 JP JP2003534428A patent/JP4101756B2/ja not_active Expired - Fee Related
- 2002-09-28 ES ES02777254T patent/ES2269772T3/es not_active Expired - Lifetime
- 2002-09-28 CN CNB028199138A patent/CN1254475C/zh not_active Expired - Fee Related
- 2002-09-28 PL PL02370565A patent/PL370565A1/xx not_active Application Discontinuation
- 2002-10-04 AR ARP020103750A patent/AR036735A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP4101756B2 (ja) | 2008-06-18 |
| RU2298009C2 (ru) | 2007-04-27 |
| EP1436292B1 (en) | 2006-08-30 |
| MXPA04003278A (es) | 2004-07-23 |
| WO2003031445A1 (en) | 2003-04-17 |
| ATE338043T1 (de) | 2006-09-15 |
| CN1254475C (zh) | 2006-05-03 |
| DE60214408T2 (de) | 2007-03-08 |
| KR100604407B1 (ko) | 2006-07-25 |
| EP1436292A1 (en) | 2004-07-14 |
| CA2462801A1 (en) | 2003-04-17 |
| KR20040044196A (ko) | 2004-05-27 |
| ES2269772T3 (es) | 2007-04-01 |
| US6693116B2 (en) | 2004-02-17 |
| PL370565A1 (en) | 2005-05-30 |
| JP2005508954A (ja) | 2005-04-07 |
| US20030134873A1 (en) | 2003-07-17 |
| AU2002338827B2 (en) | 2007-09-06 |
| CN1564821A (zh) | 2005-01-12 |
| DE60214408D1 (de) | 2006-10-12 |
| AR036735A1 (es) | 2004-09-29 |
| RU2004114277A (ru) | 2006-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2108 DE 31/05/2011. |