BR0212860A - Processo para preparação de derivados de piridil-alquilsulfonil pirazol - Google Patents

Processo para preparação de derivados de piridil-alquilsulfonil pirazol

Info

Publication number
BR0212860A
BR0212860A BR0212860-8A BR0212860A BR0212860A BR 0212860 A BR0212860 A BR 0212860A BR 0212860 A BR0212860 A BR 0212860A BR 0212860 A BR0212860 A BR 0212860A
Authority
BR
Brazil
Prior art keywords
pyrazole derivatives
pyridyl
alkylsulfonyl
preparing pyridyl
preparing
Prior art date
Application number
BR0212860-8A
Other languages
English (en)
Inventor
Dennis Ernest Bourassa
Michael James Castaldi
David Harold Brown Ripin
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0212860A publication Critical patent/BR0212860A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO PARA PREPARAçãO DE DERIVADOS DE PIRIDIL-ALQUILSULFONIL PIRAZOL". A invenção refere-se a um processo para preparação de compostos da fórmula (1): assim como intermediários úteis em tais processos, em que R^ 1^-R^ 4^ São como aqui definidos. Os compostos da fórmula (1) são úteis no tratamento ou alívio de inflamações e outros distúrbios associados com inflamações.
BR0212860-8A 2001-09-28 2002-09-19 Processo para preparação de derivados de piridil-alquilsulfonil pirazol BR0212860A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32564701P 2001-09-28 2001-09-28
PCT/IB2002/003908 WO2003029244A1 (en) 2001-09-28 2002-09-19 Process for preparing pyridyl-alkylsulfonyl pyrazole derivatives

Publications (1)

Publication Number Publication Date
BR0212860A true BR0212860A (pt) 2004-10-13

Family

ID=23268786

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0212860-8A BR0212860A (pt) 2001-09-28 2002-09-19 Processo para preparação de derivados de piridil-alquilsulfonil pirazol

Country Status (20)

Country Link
US (2) US6646128B2 (pt)
EP (1) EP1430046A1 (pt)
JP (1) JP2005504127A (pt)
KR (1) KR20040039424A (pt)
CN (1) CN1561339A (pt)
AR (1) AR036680A1 (pt)
BR (1) BR0212860A (pt)
CA (1) CA2457798A1 (pt)
CZ (1) CZ2004414A3 (pt)
GT (1) GT200200183A (pt)
HU (1) HUP0401914A3 (pt)
IL (1) IL160369A0 (pt)
MX (1) MXPA04002879A (pt)
PA (1) PA8555601A1 (pt)
PE (1) PE20030532A1 (pt)
PL (1) PL370110A1 (pt)
RU (1) RU2004109148A (pt)
UY (1) UY27453A1 (pt)
WO (1) WO2003029244A1 (pt)
ZA (1) ZA200401043B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1865955A4 (en) * 2005-03-25 2009-04-15 Merck & Co Inc TREATMENT OF MALE-HUMAN HUMANS BY TESTOSTERONE SUPPLEMENTATION ASSOCIATED WITH 5ALPHA-REDUCTASE INHIBITOR
CA2694007C (en) * 2007-07-23 2019-02-26 The Chinese University Of Hong Kong Determining a nucleic acid sequence imbalance

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH27357A (en) 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
IL104311A (en) 1992-02-05 1997-07-13 Fujisawa Pharmaceutical Co Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
US5474995A (en) 1993-06-24 1995-12-12 Merck Frosst Canada, Inc. Phenyl heterocycles as cox-2 inhibitors
US5401765A (en) 1993-11-30 1995-03-28 G. D. Searle 1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders
US5434178A (en) 1993-11-30 1995-07-18 G.D. Searle & Co. 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation
ES2193609T3 (es) 1993-11-30 2003-11-01 Searle & Co Pirazolil-bencenosulfonamidas sustituidas y su uso como inhibidores de la ciclooxigenasa ii.
US5475018A (en) 1993-11-30 1995-12-12 G. D. Searle & Co. 1,5-diphenyl pyrazole compounds for treatment of inflammation
WO1996003392A1 (en) 1994-07-27 1996-02-08 G.D. Searle & Co. Substituted thiazoles for the treatment of inflammation
US5620999A (en) 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US5585504A (en) 1994-09-16 1996-12-17 Merck & Co., Inc. Process of making cox-2 inhibitors having a lactone bridge
ES2191069T3 (es) 1994-12-21 2003-09-01 Merck Frosst Canada Inc Diaril-2-(5h)-furanonas como inhibidores de cox-2.
US5691374A (en) 1995-05-18 1997-11-25 Merck Frosst Canada Inc. Diaryl-5-oxygenated-2-(5H) -furanones as COX-2 inhibitors
US5756529A (en) 1995-09-29 1998-05-26 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies
GB9520584D0 (en) 1995-10-09 1995-12-13 Fujisawa Pharmaceutical Co Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
UA57002C2 (uk) 1995-10-13 2003-06-16 Мерк Фросст Кенада Енд Ко./Мерк Фросст Кенада Енд Сі. Похідне (метилсульфоніл)феніл-2-(5н)-фуранону, фармацевтична композиція та спосіб лікування
WO1997016435A1 (en) 1995-10-30 1997-05-09 Merck Frosst Canada Inc. 3,4-diaryl-2-hydroxy-2,5-dihydrofurans as prodrugs to cox-2 inhibitors
ES2208227T3 (es) 1999-12-03 2004-06-16 Pfizer Products Inc. Compuestos de heteroarilfenilpirazol como agentes antiinflamatorios/analgesicos.
CA2392931A1 (en) * 1999-12-03 2001-06-07 Pfizer Products Inc. Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents
DK1104758T3 (da) * 1999-12-03 2003-10-20 Pfizer Prod Inc Acetylenderivativer som anti-inflammatoriske/analgesiske lægemidler

Also Published As

Publication number Publication date
EP1430046A1 (en) 2004-06-23
GT200200183A (es) 2003-05-23
PA8555601A1 (es) 2003-09-17
HUP0401914A2 (hu) 2005-01-28
US20040044042A1 (en) 2004-03-04
US6846930B2 (en) 2005-01-25
CZ2004414A3 (cs) 2004-12-15
US6646128B2 (en) 2003-11-11
WO2003029244A8 (en) 2003-09-04
RU2004109148A (ru) 2005-08-20
WO2003029244A1 (en) 2003-04-10
US20030100765A1 (en) 2003-05-29
IL160369A0 (en) 2004-07-25
ZA200401043B (en) 2005-04-15
CN1561339A (zh) 2005-01-05
UY27453A1 (es) 2003-04-30
CA2457798A1 (en) 2003-04-10
AR036680A1 (es) 2004-09-29
PE20030532A1 (es) 2003-06-18
HUP0401914A3 (en) 2006-04-28
PL370110A1 (en) 2005-05-16
JP2005504127A (ja) 2005-02-10
KR20040039424A (ko) 2004-05-10
MXPA04002879A (es) 2004-07-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 4A,5A,6A E 7A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2034 DE 29/12/2009.