BR0209572A - Peptìdeo reativo com lipoproteìna de alta densidade - Google Patents

Peptìdeo reativo com lipoproteìna de alta densidade

Info

Publication number
BR0209572A
BR0209572A BR0209572-6A BR0209572A BR0209572A BR 0209572 A BR0209572 A BR 0209572A BR 0209572 A BR0209572 A BR 0209572A BR 0209572 A BR0209572 A BR 0209572A
Authority
BR
Brazil
Prior art keywords
amino acid
high density
peptide
cholesterol
density lipoprotein
Prior art date
Application number
BR0209572-6A
Other languages
English (en)
Inventor
Manabu Niimi
Kazushi Kanatani
Masakazu Adachi
Original Assignee
Japan Immunores Lab Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Immunores Lab Co Ltd filed Critical Japan Immunores Lab Co Ltd
Publication of BR0209572A publication Critical patent/BR0209572A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/775—Apolipopeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"PEPTìDIO REATIVO COM LIPOPROTEìNA DE ALTA DENSIDADE". Peptídio reativo com lipoproteína de alta densidade ou peptídio reativo com células espumosas conforme apresentado em um dos seguintes (a) ou (b): (a) um peptídio com a seq³ência de aminoácidos representada por SEQ ID NO: 1; e (b) um peptídio com uma seq³ência de aminoácidos derivada da seq³ência de aminoácidos especificada em (a) acima por substituição, deleção, adição ou inserção de um ou mais resíduos de aminoácidos e que é capaz de se ligar especificamente a colesterol de lipoproteína de alta densidade ou de retirar colesterol de células espumosas. Assim, apresentam-se peptídios com novas seq³ências de aminoácidos e que são capazes de se ligarem especificamente a colesterol HDL ou de retirar colesterol de células espumosas. Esses peptídios são utilizáveis como medicamentos ara várias doenças causadas por arteriosclerose, erros metabólicos de lipídios e colesterose periférica.
BR0209572-6A 2001-05-15 2002-05-15 Peptìdeo reativo com lipoproteìna de alta densidade BR0209572A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001144304 2001-05-15
PCT/JP2002/004697 WO2002092630A1 (en) 2001-05-15 2002-05-15 High density lipoprotein-reactive peptides

Publications (1)

Publication Number Publication Date
BR0209572A true BR0209572A (pt) 2004-07-13

Family

ID=18990273

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209572-6A BR0209572A (pt) 2001-05-15 2002-05-15 Peptìdeo reativo com lipoproteìna de alta densidade

Country Status (10)

Country Link
US (1) US7241861B2 (pt)
EP (1) EP1394177A4 (pt)
JP (1) JP3944083B2 (pt)
KR (1) KR20030097854A (pt)
CN (1) CN1312178C (pt)
BR (1) BR0209572A (pt)
CA (1) CA2446720A1 (pt)
MX (1) MXPA03010456A (pt)
RU (1) RU2003136090A (pt)
WO (1) WO2002092630A1 (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030105003A1 (en) 2001-04-05 2003-06-05 Jan Nilsson Peptide-based immunization therapy for treatment of atherosclerosis and development of peptide-based assay for determination of immune responses against oxidized low density lipoprotein
SE0103754L (sv) * 2001-04-05 2002-10-06 Forskarpatent I Syd Ab Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid
IL161110A0 (en) 2001-09-28 2004-08-31 Esperion Therapeutics Inc Prevention and treatment of restenosis by local admistration of drug
JP2007531537A (ja) 2004-04-06 2007-11-08 セダーズ−シナイ　メディカル　センター アポリポタンパク質ａ−ｉおよびアポリポタンパク質ａ−ｉｍｉｌａｎｏをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置
KR100956893B1 (ko) * 2006-09-25 2010-05-11 (주)에스제이바이오메드 항비만용 면역원성 하이브리드 폴리펩타이드 및 이를포함하는 항비만 백신 조성물
WO2010080007A2 (ko) * 2009-01-09 2010-07-15 부산대학교 산학협력단 Ｔｏｌｌ 유사수용체２ 리간드로서 기능하는 그람양성균 유래의 리포단백질
US9205139B2 (en) 2010-11-12 2015-12-08 Cardiovax, Llc Immunomodulatory methods and systems for treatment and/or prevention of aneurysms
RU2013126626A (ru) 2010-11-12 2014-12-20 Седарс-Синаи Медикал Сентер Иммуномодулирующие способы и системы для лечения и/или предотвращения гипертензий

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0239631A4 (en) * 1985-10-04 1989-01-12 Biotech Res Partners Ltd RECOMBINANT APOLIPOPROTEINS AND METHODS.
JP2657225B2 (ja) 1987-03-31 1997-09-24 株式会社 日本抗体研究所 脂質代謝異常の検出方法
JP3043528B2 (ja) 1992-10-30 2000-05-22 株式会社日本抗体研究所 コレステリルエステル転送蛋白の測定法
GB9609702D0 (en) * 1996-05-09 1996-07-10 Royal Free Hosp School Med Anticoagulant peptides
US6635623B1 (en) * 1997-06-13 2003-10-21 Baylor College Of Medicine Lipoproteins as nucleic acid vectors

Also Published As

Publication number Publication date
EP1394177A4 (en) 2005-03-30
CN1509294A (zh) 2004-06-30
JPWO2002092630A1 (ja) 2004-08-26
CN1312178C (zh) 2007-04-25
US20040242474A1 (en) 2004-12-02
EP1394177A1 (en) 2004-03-03
RU2003136090A (ru) 2005-04-20
WO2002092630A1 (en) 2002-11-21
MXPA03010456A (es) 2004-12-06
US7241861B2 (en) 2007-07-10
KR20030097854A (ko) 2003-12-31
JP3944083B2 (ja) 2007-07-11
CA2446720A1 (en) 2002-11-21

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: JIMRO CO., LTD. (JP)

Free format text: ALTERADO DE: JAPAN IMMUNORESEARCH LABORATORIES CO., LTD.

B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A , 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2029 DE 24/11/2009.