BR0209518A - Novos derivados arilheteroalquilamina - Google Patents

Novos derivados arilheteroalquilamina

Info

Publication number
BR0209518A
BR0209518A BR0209518-1A BR0209518A BR0209518A BR 0209518 A BR0209518 A BR 0209518A BR 0209518 A BR0209518 A BR 0209518A BR 0209518 A BR0209518 A BR 0209518A
Authority
BR
Brazil
Prior art keywords
derivatives
new
aryletheroalkylamine
compounds
arilheteroalkylamines
Prior art date
Application number
BR0209518-1A
Other languages
English (en)
Inventor
Tim Birkinshaw
Stephen Connolly
Timothy Luker
Antonio Mete
Ian Millichip
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SE0101617A external-priority patent/SE0101617D0/xx
Priority claimed from SE0103271A external-priority patent/SE0103271D0/xx
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BR0209518A publication Critical patent/BR0209518A/pt

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
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    • C07C323/29—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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    • C07C323/35—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group
    • C07C323/36—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to a carbon atom of the same non-condensed six-membered aromatic ring the thio group being a sulfide group the sulfur atom of the sulfide group being further bound to an acyclic carbon atom
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

"NOVOS DERIVADOS ARILHETEROALQUILAMINAS". São fornecidos novos compostos de fórmula (I) aonde R1, R2, R3, R4, R5, R6, T, U, X, Y, V e W são como definidos na especificação, e sais farmaceuticamente aceitáveis dos mesmos, e enantiómeros e racematos dos mesmos; junto com processos para suas preparações, composições contendo os mesmos e seus usos em terapia. Os compostos são inibidores da sintase do óxido nítrico e são desta maneira particularmente úteis no tratamento ou profilaxia de doença inflamatória e dor.
BR0209518-1A 2001-05-08 2002-05-06 Novos derivados arilheteroalquilamina BR0209518A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE0101617A SE0101617D0 (sv) 2001-05-08 2001-05-08 Novel compounds
SE0103271A SE0103271D0 (sv) 2001-09-28 2001-09-28 Novel compounds
PCT/SE2002/000876 WO2002090332A2 (en) 2001-05-08 2002-05-06 Novel aeylheteroalkylaminε derivatives

Publications (1)

Publication Number Publication Date
BR0209518A true BR0209518A (pt) 2004-07-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR0209518-1A BR0209518A (pt) 2001-05-08 2002-05-06 Novos derivados arilheteroalquilamina

Country Status (15)

Country Link
US (1) US20040242871A1 (pt)
EP (1) EP1572655A2 (pt)
JP (1) JP2005506308A (pt)
KR (1) KR20030096361A (pt)
CN (1) CN100340548C (pt)
AR (1) AR035700A1 (pt)
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KR20030096361A (ko) 2003-12-24
JP2005506308A (ja) 2005-03-03
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EP1572655A2 (en) 2005-09-14
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AU2002306039B2 (en) 2008-05-29
CA2446120A1 (en) 2002-11-14
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