BR0015199A - Composto, composição, e, método para tratar um paciente que tem uma condição médica para a qual um inibidor do transporte de glicina é indicado - Google Patents
Composto, composição, e, método para tratar um paciente que tem uma condição médica para a qual um inibidor do transporte de glicina é indicadoInfo
- Publication number
- BR0015199A BR0015199A BR0015199-8A BR0015199A BR0015199A BR 0015199 A BR0015199 A BR 0015199A BR 0015199 A BR0015199 A BR 0015199A BR 0015199 A BR0015199 A BR 0015199A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- substituted
- cycloalkyl
- alkyl
- independently selected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Confectionery (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43102299A | 1999-11-01 | 1999-11-01 | |
| PCT/US2000/030074 WO2001032602A1 (en) | 1999-11-01 | 2000-11-01 | Diaryl-enynes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015199A true BR0015199A (pt) | 2002-07-09 |
Family
ID=23710104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015199-8A BR0015199A (pt) | 1999-11-01 | 2000-11-01 | Composto, composição, e, método para tratar um paciente que tem uma condição médica para a qual um inibidor do transporte de glicina é indicado |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1226108A4 (no) |
| JP (1) | JP2003513063A (no) |
| KR (1) | KR100702717B1 (no) |
| CN (1) | CN100357274C (no) |
| AU (1) | AU780922C (no) |
| BG (1) | BG65275B1 (no) |
| BR (1) | BR0015199A (no) |
| CA (1) | CA2387660A1 (no) |
| CZ (1) | CZ20021545A3 (no) |
| EA (1) | EA004602B1 (no) |
| EE (1) | EE05031B1 (no) |
| HR (1) | HRP20020376A2 (no) |
| HU (1) | HUP0203182A3 (no) |
| IL (1) | IL149347A0 (no) |
| MX (1) | MXPA02004354A (no) |
| NO (1) | NO20021936L (no) |
| NZ (1) | NZ529245A (no) |
| PL (1) | PL355425A1 (no) |
| SK (1) | SK6202002A3 (no) |
| UA (1) | UA73749C2 (no) |
| WO (1) | WO2001032602A1 (no) |
| ZA (1) | ZA200203458B (no) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04225953A (ja) * | 1990-05-07 | 1992-08-14 | Shionogi & Co Ltd | スピロ ジベンゾスベラン誘導体 |
| ATE136461T1 (de) * | 1990-08-13 | 1996-04-15 | Searle & Co | Verwendung von heterozyklischen aminoalkoholverbindungen zur herstellung eines medikaments für die behandlung von erkrankungen des zns |
| PT871440E (pt) * | 1995-12-07 | 2006-07-31 | Daniel C Javitt | Tratamento de sintomas negativos e cognitivos de esquizofrenia com antagonistas da captacao de glicina |
| UA52698C2 (uk) * | 1996-10-04 | 2003-01-15 | Х. Луннбек А/С | Похідні (3-алкоксіізоксазол-4-іл)заміщеної 2-амінокарбонової кислоти та їх сірковмісні аналоги, фармацевтична композиція на їх основі |
| AU3254499A (en) * | 1998-03-06 | 1999-09-20 | Janssen Pharmaceutica N.V. | Glycine transport inhibitors |
| EP1059922A2 (en) * | 1998-03-06 | 2000-12-20 | Janssen Pharmaceutica N.V. | Glycine transport inhibitors |
| PE20000728A1 (es) * | 1998-06-26 | 2000-08-21 | Cocensys Inc | Heterociclos 4-bencil piperidina alquilsulfoxido y su uso como antagonistas receptores subtipo-selectivo nmda |
| US6103743A (en) * | 1999-08-06 | 2000-08-15 | Allelix Neuroscience, Inc. | Unsaturated amino acid derivatives |
-
2000
- 2000-01-11 UA UA2002043703A patent/UA73749C2/uk unknown
- 2000-11-01 JP JP2001534756A patent/JP2003513063A/ja active Pending
- 2000-11-01 NZ NZ529245A patent/NZ529245A/en active Application Filing
- 2000-11-01 KR KR1020027005593A patent/KR100702717B1/ko not_active IP Right Cessation
- 2000-11-01 CN CNB008151970A patent/CN100357274C/zh not_active Expired - Fee Related
- 2000-11-01 EA EA200200521A patent/EA004602B1/ru not_active IP Right Cessation
- 2000-11-01 PL PL00355425A patent/PL355425A1/xx not_active IP Right Cessation
- 2000-11-01 WO PCT/US2000/030074 patent/WO2001032602A1/en active IP Right Grant
- 2000-11-01 CZ CZ20021545A patent/CZ20021545A3/cs unknown
- 2000-11-01 MX MXPA02004354A patent/MXPA02004354A/es active IP Right Grant
- 2000-11-01 HU HU0203182A patent/HUP0203182A3/hu unknown
- 2000-11-01 BR BR0015199-8A patent/BR0015199A/pt not_active Application Discontinuation
- 2000-11-01 CA CA002387660A patent/CA2387660A1/en not_active Abandoned
- 2000-11-01 EP EP00976775A patent/EP1226108A4/en not_active Withdrawn
- 2000-11-01 IL IL14934700A patent/IL149347A0/xx unknown
- 2000-11-01 AU AU14507/01A patent/AU780922C/en not_active Ceased
- 2000-11-01 EE EEP200200229A patent/EE05031B1/xx not_active IP Right Cessation
- 2000-11-01 SK SK620-2002A patent/SK6202002A3/sk unknown
-
2002
- 2002-04-24 NO NO20021936A patent/NO20021936L/no not_active Application Discontinuation
- 2002-04-29 HR HR20020376A patent/HRP20020376A2/hr not_active Application Discontinuation
- 2002-04-30 BG BG106671A patent/BG65275B1/bg unknown
- 2002-04-30 ZA ZA200203458A patent/ZA200203458B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20020376A2 (en) | 2004-02-29 |
| EA200200521A1 (ru) | 2002-10-31 |
| EP1226108A1 (en) | 2002-07-31 |
| NO20021936D0 (no) | 2002-04-24 |
| HUP0203182A2 (hu) | 2003-01-28 |
| CZ20021545A3 (cs) | 2002-10-16 |
| EA004602B1 (ru) | 2004-06-24 |
| AU780922B2 (en) | 2005-04-28 |
| CN100357274C (zh) | 2007-12-26 |
| MXPA02004354A (es) | 2003-10-06 |
| PL355425A1 (en) | 2004-04-19 |
| EE200200229A (et) | 2003-06-16 |
| AU780922C (en) | 2005-10-20 |
| CN1387507A (zh) | 2002-12-25 |
| EP1226108A4 (en) | 2004-06-16 |
| KR20020060961A (ko) | 2002-07-19 |
| CA2387660A1 (en) | 2001-05-10 |
| NZ529245A (en) | 2005-09-30 |
| BG106671A (en) | 2003-02-28 |
| UA73749C2 (en) | 2005-09-15 |
| ZA200203458B (en) | 2003-10-29 |
| EE05031B1 (et) | 2008-06-16 |
| WO2001032602A1 (en) | 2001-05-10 |
| HUP0203182A3 (en) | 2003-04-28 |
| AU1450701A (en) | 2001-05-14 |
| NO20021936L (no) | 2002-07-01 |
| SK6202002A3 (en) | 2002-10-08 |
| KR100702717B1 (ko) | 2007-04-03 |
| IL149347A0 (en) | 2002-11-10 |
| JP2003513063A (ja) | 2003-04-08 |
| BG65275B1 (bg) | 2007-11-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2008228597B2 (en) | Stabilization of vitamin B12 | |
| BR0115446A (pt) | Processos para tratamento de condições associadas a quinase p38 e compostos pirrolotriazina úteis como inibidores de quinase | |
| EE04548B1 (et) | Aminotskloheksleeterhendid, nende kompositsioonid ja nende kasutamine | |
| AU731946B2 (en) | Local anesthetic for external use | |
| IE873215L (en) | Antimicrobial proteins, compositions containing same and¹uses thereof | |
| GR81149B (en) | Growth promotants for animals | |
| CA2120538A1 (en) | Use of Bisphosphonic Acid Derivatives for Promoting Bone Repair and Corresponding Drugs | |
| KR890003704A (ko) | 7-치환체의 측쇄에 α- 아미노산을 포함하는 퀴놀른 및 나프티리딘 항균제 | |
| DK0888293T3 (da) | N-acylaminoalkylhydrazin-carboximidamider | |
| DE69202876D1 (de) | Inhibitoren von N-Myristoyltransferase, deren Verfahren zur Herstellung und die sie enthaltenden pharmazeutischen Zusammensetzungen. | |
| MY114944A (en) | Propanolamine derivatives, processes for their preparation pharmaceuticals comprising these compounds, and their use | |
| ATE59757T1 (de) | Phospholipidhaltige produkte, deren herstellung und verwendung. | |
| BRPI0417902A (pt) | piperazinas úteis no tratamento da dor | |
| BR0015199A (pt) | Composto, composição, e, método para tratar um paciente que tem uma condição médica para a qual um inibidor do transporte de glicina é indicado | |
| BR0317433A (pt) | Derivados bicìclicos para o tratamento do crescimento celular anormal | |
| O’Neil-Cutting et al. | Effect of excess dietary zinc on tissue storage of iron in rats | |
| CY1104974T1 (el) | Χρηση παραγωγου του διφωσφονικου οξεος για τηn παρασκευη ενος φαρμακου που προοριζεται για τη θεραπεια της χωλοτητας | |
| MY136145A (en) | TREATMENT OF RUMEN ACIDOSIS WITH (a)-AMYLASE INHIBITORS | |
| ATE22685T1 (de) | Substituierte 1,3-diazolyl-2-propanole, verfahren zu ihrer herstellung und ihre verwendung als antimykotische mittel. | |
| GR851467B (no) | ||
| EA200100584A1 (ru) | Фосфорорганические соединения и их применение | |
| Jones et al. | Control of nephrotoxicity in the rat during repeated cis‐platinum treatments | |
| ZA918991B (en) | Imidazole compounds,process for the preparation thereof and pharmaceutical compositions containing them | |
| TW287086B (no) | ||
| Massie et al. | Excess dietary aluminum increases Drosophila’s rate of aging |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B15G | Petition not considered as such [chapter 15.7 patent gazette] |
Free format text: DESCONHECIDA DA PETICAO NO 020080143316/RJ DE 17/11/2008, O PRIMEIRO ATO DE TRANSFERENCIA POR FUSAO, UMA VEZ QUE O PEDIDO JA SE ENCONTRA EM NOME DE NPS ALLELIX CORP. |
|
| B25A | Requested transfer of rights approved |
Owner name: NPS PHARMACEUTICALS, INC. (US) Free format text: TRANSFERIDO DE: NPS ALLELIX CORP. |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |