BR0015199A - A compound, composition, and method for treating a patient who has a medical condition for which a glycine transport inhibitor is indicated - Google Patents
A compound, composition, and method for treating a patient who has a medical condition for which a glycine transport inhibitor is indicatedInfo
- Publication number
- BR0015199A BR0015199A BR0015199-8A BR0015199A BR0015199A BR 0015199 A BR0015199 A BR 0015199A BR 0015199 A BR0015199 A BR 0015199A BR 0015199 A BR0015199 A BR 0015199A
- Authority
- BR
- Brazil
- Prior art keywords
- group
- substituted
- cycloalkyl
- alkyl
- independently selected
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/40—Y being a hydrogen or a carbon atom
- C07C323/41—Y being a hydrogen or an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/58—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Confectionery (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Quinoline Compounds (AREA)
- Furan Compounds (AREA)
- Pyrrole Compounds (AREA)
Abstract
"COMPOSTO, COMPOSIçãO, E, MéTODO PARA TRATAR UM PACIENTE QUE TEM UMA CONDIçãO MéDICA PARA A QUAL UM INIBIDOR DO TRANSPORTE DE GLICINA E INDICADO". é fornecido, entre outras coisas, um composto da Fórmula (I), em que, Ar~ 1~ e Ar~ 2~ são independentemente selecionados de grupos arila, opcionalmente substituídos por até cinco substituintes independentemente selecionados do grupo que consiste de alquila, alcóxi, cicloalquila, cicloalquilóxi, heterocicloalquila, heterocicloalquilóxi, alcanoíla, tioalquila, aralquila, aralquilóxi, ariloxialquila, arilóxialcóxi, alquila substituída por cicloalquila, alquila substituída por cicloalquilóxi, alcóxi substituído por cicloalquila, alcóxi substituído por cicloalquilóxi, alquila substituída por heterocicloalquila, alquila substituída por heterocicloalquilóxi, alcóxi substituído por heterocicloalquila, alcóxi substituído por heterocicloalquilóxi, tioarila, aralquiltio, tioarilalquila, aralquiltioalquila, halo, NO~ 2~,CF~ 3~, CN, OH, alquilenodióxi, SO~ 2~NRR', NRR', CO~ 2~R (onde R e R' são independentemente selecionados do grupo que consiste de H e alquila) e um segundo grupo arila, que pode ser substituído como acima; R~ 1~ é selecionado do grupo que consiste de H e alquila; R~ 2~ é selecionado do grupo que consiste de H, alquila e benzila; R~ 3~ é selecionado do grupo que consiste de CO~ 2~R, CONRR', CONH(OH), COSR, SO~ 2~NRR', PO(OR)OR') e tetrazolila, em que R e R' são independentemente selecionados do grupo que consiste de H e alquila; e um sal, solvato ou hidrato deste."COMPOSITE, COMPOSITION, AND, METHOD FOR TREATING A PATIENT WHO HAS A MEDICAL CONDITION FOR WHICH A GLYCIN TRANSPORT INHIBITOR IS INDICATED". a compound of Formula (I) is provided, among other things, in which, Ar ~ 1 ~ and Ar ~ 2 ~ are independently selected from aryl groups, optionally substituted by up to five substituents independently selected from the group consisting of alkyl, alkoxy , cycloalkyl, cycloalkyloxy, heterocycloalkyl, heterocycloalkyloxy, alkanoyl, thioalkyl, aralkyl, aralkyloxy, aryloxyalkyl, aryloxyalkoxy, cycloalkyl substituted alkyl, heteroalkyl substituted by cycloalkyl, alkoxy substituted by cycloalkyl, substituted by cycloalkyl, substituted by cycloalkyl , alkoxy substituted by heterocycloalkyl, alkoxy substituted by heterocycloalkyloxy, thioaryl, aralkylthio, thioarylalkyl, aralkylthioalkyl, halo, NO ~ 2 ~, CF ~ 3 ~, CN, OH, alkylenedioxy, SO ~ 2 ~ NRR ', NRR', CO ~ 2 ~ R (where R and R 'are independently selected from the group consisting of H and alkyl) and an s second aryl group, which can be replaced as above; R ~ 1 ~ is selected from the group consisting of H and alkyl; R ~ 2 ~ is selected from the group consisting of H, alkyl and benzyl; R ~ 3 ~ is selected from the group consisting of CO ~ 2 ~ R, CONRR ', CONH (OH), COSR, SO ~ 2 ~ NRR', PO (OR) OR ') and tetrazolyl, where R and R' they are independently selected from the group consisting of H and alkyl; and a salt, solvate or hydrate thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43102299A | 1999-11-01 | 1999-11-01 | |
| PCT/US2000/030074 WO2001032602A1 (en) | 1999-11-01 | 2000-11-01 | Diaryl-enynes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015199A true BR0015199A (en) | 2002-07-09 |
Family
ID=23710104
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015199-8A BR0015199A (en) | 1999-11-01 | 2000-11-01 | A compound, composition, and method for treating a patient who has a medical condition for which a glycine transport inhibitor is indicated |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1226108A4 (en) |
| JP (1) | JP2003513063A (en) |
| KR (1) | KR100702717B1 (en) |
| CN (1) | CN100357274C (en) |
| AU (1) | AU780922C (en) |
| BG (1) | BG65275B1 (en) |
| BR (1) | BR0015199A (en) |
| CA (1) | CA2387660A1 (en) |
| CZ (1) | CZ20021545A3 (en) |
| EA (1) | EA004602B1 (en) |
| EE (1) | EE05031B1 (en) |
| HR (1) | HRP20020376A2 (en) |
| HU (1) | HUP0203182A3 (en) |
| IL (1) | IL149347A0 (en) |
| MX (1) | MXPA02004354A (en) |
| NO (1) | NO20021936L (en) |
| NZ (1) | NZ529245A (en) |
| PL (1) | PL355425A1 (en) |
| SK (1) | SK6202002A3 (en) |
| UA (1) | UA73749C2 (en) |
| WO (1) | WO2001032602A1 (en) |
| ZA (1) | ZA200203458B (en) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04225953A (en) * | 1990-05-07 | 1992-08-14 | Shionogi & Co Ltd | Spiro dibenzosuberane derivative |
| ATE136461T1 (en) * | 1990-08-13 | 1996-04-15 | Searle & Co | USE OF HETEROCYCLIC AMINO ALCOHOL COMPOUNDS FOR THE PRODUCTION OF A MEDICATION FOR THE TREATMENT OF CNS DISEASES |
| ATE320804T1 (en) * | 1995-12-07 | 2006-04-15 | Daniel C Javitt | TREATMENT OF NEGATIVE AND COGNITIVE SYMPTOMS OF SCHIZOPHRENIA WITH ANTAGONISTS OF GLYCINE ABSORPTION |
| UA52698C2 (en) * | 1996-10-04 | 2003-01-15 | Х. Луннбек А/С | (3-Alkoxyisoxazol-4-yl)-substituted 2-amino carboxylic acid derivatives |
| BR9907951A (en) * | 1998-03-06 | 2001-01-30 | Janssen Pharmaceutica Nv | Glycine transport inhibitors |
| CA2322136A1 (en) * | 1998-03-06 | 1999-09-10 | Ludo Edmond Josephine Kennis | Glycine transport inhibitors |
| PE20000728A1 (en) * | 1998-06-26 | 2000-08-21 | Cocensys Inc | HETEROCYCLES 4-BENZYL PIPERIDINE ALKYLSULFOXIDE AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS |
| US6103743A (en) * | 1999-08-06 | 2000-08-15 | Allelix Neuroscience, Inc. | Unsaturated amino acid derivatives |
-
2000
- 2000-01-11 UA UA2002043703A patent/UA73749C2/en unknown
- 2000-11-01 CA CA002387660A patent/CA2387660A1/en not_active Abandoned
- 2000-11-01 AU AU14507/01A patent/AU780922C/en not_active Ceased
- 2000-11-01 HU HU0203182A patent/HUP0203182A3/en unknown
- 2000-11-01 BR BR0015199-8A patent/BR0015199A/en not_active Application Discontinuation
- 2000-11-01 JP JP2001534756A patent/JP2003513063A/en active Pending
- 2000-11-01 SK SK620-2002A patent/SK6202002A3/en unknown
- 2000-11-01 WO PCT/US2000/030074 patent/WO2001032602A1/en active IP Right Grant
- 2000-11-01 EP EP00976775A patent/EP1226108A4/en not_active Withdrawn
- 2000-11-01 MX MXPA02004354A patent/MXPA02004354A/en active IP Right Grant
- 2000-11-01 KR KR1020027005593A patent/KR100702717B1/en not_active IP Right Cessation
- 2000-11-01 CZ CZ20021545A patent/CZ20021545A3/en unknown
- 2000-11-01 EA EA200200521A patent/EA004602B1/en not_active IP Right Cessation
- 2000-11-01 NZ NZ529245A patent/NZ529245A/en active Application Filing
- 2000-11-01 EE EEP200200229A patent/EE05031B1/en not_active IP Right Cessation
- 2000-11-01 PL PL00355425A patent/PL355425A1/en not_active IP Right Cessation
- 2000-11-01 CN CNB008151970A patent/CN100357274C/en not_active Expired - Fee Related
- 2000-11-01 IL IL14934700A patent/IL149347A0/en unknown
-
2002
- 2002-04-24 NO NO20021936A patent/NO20021936L/en not_active Application Discontinuation
- 2002-04-29 HR HR20020376A patent/HRP20020376A2/en not_active Application Discontinuation
- 2002-04-30 ZA ZA200203458A patent/ZA200203458B/en unknown
- 2002-04-30 BG BG106671A patent/BG65275B1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU780922C (en) | 2005-10-20 |
| HUP0203182A2 (en) | 2003-01-28 |
| KR100702717B1 (en) | 2007-04-03 |
| HUP0203182A3 (en) | 2003-04-28 |
| IL149347A0 (en) | 2002-11-10 |
| MXPA02004354A (en) | 2003-10-06 |
| ZA200203458B (en) | 2003-10-29 |
| NO20021936L (en) | 2002-07-01 |
| EP1226108A4 (en) | 2004-06-16 |
| UA73749C2 (en) | 2005-09-15 |
| HRP20020376A2 (en) | 2004-02-29 |
| CA2387660A1 (en) | 2001-05-10 |
| WO2001032602A1 (en) | 2001-05-10 |
| PL355425A1 (en) | 2004-04-19 |
| NO20021936D0 (en) | 2002-04-24 |
| EA200200521A1 (en) | 2002-10-31 |
| EA004602B1 (en) | 2004-06-24 |
| EP1226108A1 (en) | 2002-07-31 |
| JP2003513063A (en) | 2003-04-08 |
| SK6202002A3 (en) | 2002-10-08 |
| NZ529245A (en) | 2005-09-30 |
| EE05031B1 (en) | 2008-06-16 |
| CN100357274C (en) | 2007-12-26 |
| AU1450701A (en) | 2001-05-14 |
| AU780922B2 (en) | 2005-04-28 |
| CZ20021545A3 (en) | 2002-10-16 |
| BG65275B1 (en) | 2007-11-30 |
| EE200200229A (en) | 2003-06-16 |
| KR20020060961A (en) | 2002-07-19 |
| CN1387507A (en) | 2002-12-25 |
| BG106671A (en) | 2003-02-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0115446A (en) | Processes for treating p38 kinase-associated conditions and pyrrolotriazine compounds useful as kinase inhibitors | |
| EE04548B1 (en) | Aminots cloheks measles compounds, their compositions and their use | |
| AU731946B2 (en) | Local anesthetic for external use | |
| IE873215L (en) | Antimicrobial proteins, compositions containing same and¹uses thereof | |
| GB8332704D0 (en) | Growth promotants for animals | |
| CA2120538A1 (en) | Use of Bisphosphonic Acid Derivatives for Promoting Bone Repair and Corresponding Drugs | |
| KR890003704A (en) | Quinol and naphthyridine antimicrobials comprising α-amino acids in the side chain of the 7-substituent | |
| CY1105796T1 (en) | TREATMENT OF RUMINANT ACIDICATION WITH ALPHA-AMYLASE INHIBITORS | |
| DE602004014791D1 (en) | PHENYLIC ACIDIC ACID AMID COMPOUNDS SUITABLE FOR THE TREATMENT OF PAIN | |
| NZ196284A (en) | 1-piperazino-3-phenylindane derivatives:pharmaceutical compositions | |
| DK0888293T3 (en) | N-acylaminoalkylhydrazine carboximidamides | |
| DE69202876D1 (en) | Inhibitors of N-myristoyl transferase, their method of preparation and the pharmaceutical compositions containing them. | |
| ATE59757T1 (en) | PHOSPHOLIPID CONTAINING PRODUCTS, THEIR MANUFACTURE AND USE. | |
| BRPI0417902A (en) | piperazines useful in pain management | |
| BR0015199A (en) | A compound, composition, and method for treating a patient who has a medical condition for which a glycine transport inhibitor is indicated | |
| O’Neil-Cutting et al. | Effect of excess dietary zinc on tissue storage of iron in rats | |
| CY1104974T1 (en) | USE OF A DERIVATIVE OF DIPHOSPHONIC ACID FOR THE PREPARATION OF A MEDICATION INTENDED FOR THE TREATMENT OF BILITIVITY | |
| ATE22685T1 (en) | SUBSTITUTED 1,3-DIAZOLYL-2-PROPANOLS, PROCESS FOR THEIR PRODUCTION AND USE AS ANTIFUNCTIONAL AGENTS. | |
| GR851467B (en) | ||
| EA200100584A1 (en) | ORGANOPHOSPHORUS COMPOUNDS AND THEIR APPLICATION | |
| ATE37533T1 (en) | DERIVATIVES OF 4-PHENYL-4-OXO-BUTENE-2-ACID, PROCESS FOR THEIR PREPARATION, MEDICATIONS AND MIXTURES WITH THESE DERIVATIVES. | |
| EA200001029A1 (en) | HYGROMYCIN DERIVATIVES | |
| ZA918991B (en) | Imidazole compounds,process for the preparation thereof and pharmaceutical compositions containing them | |
| EA200101170A1 (en) | HALOGEN DERIVATIVES 9-DEOXO-9A-AZA-9A-Homoeritromycin A | |
| ES2132439T3 (en) | COMPOSITION FOR THE CONSERVATION OF A LUNG GRAFT AND METHOD FOR THE VIABLE CONSERVATION OF LUNG GRAFT. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B15G | Petition not considered as such [chapter 15.7 patent gazette] |
Free format text: DESCONHECIDA DA PETICAO NO 020080143316/RJ DE 17/11/2008, O PRIMEIRO ATO DE TRANSFERENCIA POR FUSAO, UMA VEZ QUE O PEDIDO JA SE ENCONTRA EM NOME DE NPS ALLELIX CORP. |
|
| B25A | Requested transfer of rights approved |
Owner name: NPS PHARMACEUTICALS, INC. (US) Free format text: TRANSFERIDO DE: NPS ALLELIX CORP. |
|
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements |