EE200200229A - Diarylenines, composition and pharmaceutical composition - Google Patents

Diarylenines, composition and pharmaceutical composition

Info

Publication number
EE200200229A
EE200200229A EEP200200229A EEP200200229A EE200200229A EE 200200229 A EE200200229 A EE 200200229A EE P200200229 A EEP200200229 A EE P200200229A EE P200200229 A EEP200200229 A EE P200200229A EE 200200229 A EE200200229 A EE 200200229A
Authority
EE
Estonia
Prior art keywords
composition
diarylenines
pharmaceutical composition
pharmaceutical
Prior art date
Application number
EEP200200229A
Other languages
Estonian (et)
Inventor
Egle Ian
Frey Jennifer
Isaac Methvin
Original Assignee
Nps Allelix Corp.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nps Allelix Corp. filed Critical Nps Allelix Corp.
Publication of EE200200229A publication Critical patent/EE200200229A/en
Publication of EE05031B1 publication Critical patent/EE05031B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
EEP200200229A 1999-11-01 2000-11-01 Diaries, composition, pharmaceutical composition and use of diaries EE05031B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43102299A 1999-11-01 1999-11-01
PCT/US2000/030074 WO2001032602A1 (en) 1999-11-01 2000-11-01 Diaryl-enynes

Publications (2)

Publication Number Publication Date
EE200200229A true EE200200229A (en) 2003-06-16
EE05031B1 EE05031B1 (en) 2008-06-16

Family

ID=23710104

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200229A EE05031B1 (en) 1999-11-01 2000-11-01 Diaries, composition, pharmaceutical composition and use of diaries

Country Status (22)

Country Link
EP (1) EP1226108A4 (en)
JP (1) JP2003513063A (en)
KR (1) KR100702717B1 (en)
CN (1) CN100357274C (en)
AU (1) AU780922C (en)
BG (1) BG65275B1 (en)
BR (1) BR0015199A (en)
CA (1) CA2387660A1 (en)
CZ (1) CZ20021545A3 (en)
EA (1) EA004602B1 (en)
EE (1) EE05031B1 (en)
HR (1) HRP20020376A2 (en)
HU (1) HUP0203182A3 (en)
IL (1) IL149347A0 (en)
MX (1) MXPA02004354A (en)
NO (1) NO20021936L (en)
NZ (1) NZ529245A (en)
PL (1) PL355425A1 (en)
SK (1) SK6202002A3 (en)
UA (1) UA73749C2 (en)
WO (1) WO2001032602A1 (en)
ZA (1) ZA200203458B (en)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04225953A (en) * 1990-05-07 1992-08-14 Shionogi & Co Ltd Spiro dibenzosuberane derivative
JPH06500099A (en) * 1990-08-13 1994-01-06 ジー．ディー．サール　アンド　カンパニー Use of heterocyclic amino-alcohol compounds in the treatment of CNS diseases
PT871440E (en) * 1995-12-07 2006-07-31 Daniel C Javitt TREATMENT OF NEGATIVE AND COGNITIVE SYMPTOMS OF SCHIZOPHRENIA WITH ANTAGONISTS OF GLYCINE CAPTACAO
UA52698C2 (en) * 1996-10-04 2003-01-15 Х. Луннбек А/С (3-Alkoxyisoxazol-4-yl)-substituted 2-amino carboxylic acid derivatives
SK13092000A3 (en) * 1998-03-06 2001-03-12 Janssen Pharmaceutica N. V. Glycine transport inhibitors
HUP0101048A2 (en) * 1998-03-06 2001-10-28 Janssen Pharmaceutica N.V. Glycine transport inhibiting [4,4-bis(4-fluorophenyl)butyl]-1-(piperazinyl and piperidinyl) derivatives and their therapeutic use
PE20000728A1 (en) * 1998-06-26 2000-08-21 Cocensys Inc HETEROCYCLES 4-BENZYL PIPERIDINE ALKYLSULFOXIDE AND THEIR USE AS SUBTYPE-SELECTIVE NMDA RECEPTOR ANTAGONISTS
US6103743A (en) * 1999-08-06 2000-08-15 Allelix Neuroscience, Inc. Unsaturated amino acid derivatives

Also Published As

Publication number Publication date
MXPA02004354A (en) 2003-10-06
IL149347A0 (en) 2002-11-10
AU780922B2 (en) 2005-04-28
HUP0203182A2 (en) 2003-01-28
ZA200203458B (en) 2003-10-29
CN1387507A (en) 2002-12-25
WO2001032602A1 (en) 2001-05-10
EP1226108A4 (en) 2004-06-16
AU780922C (en) 2005-10-20
BG65275B1 (en) 2007-11-30
EA200200521A1 (en) 2002-10-31
NO20021936L (en) 2002-07-01
CA2387660A1 (en) 2001-05-10
JP2003513063A (en) 2003-04-08
NO20021936D0 (en) 2002-04-24
CN100357274C (en) 2007-12-26
CZ20021545A3 (en) 2002-10-16
AU1450701A (en) 2001-05-14
PL355425A1 (en) 2004-04-19
HRP20020376A2 (en) 2004-02-29
BR0015199A (en) 2002-07-09
HUP0203182A3 (en) 2003-04-28
KR100702717B1 (en) 2007-04-03
EA004602B1 (en) 2004-06-24
UA73749C2 (en) 2005-09-15
EP1226108A1 (en) 2002-07-31
KR20020060961A (en) 2002-07-19
EE05031B1 (en) 2008-06-16
BG106671A (en) 2003-02-28
NZ529245A (en) 2005-09-30
SK6202002A3 (en) 2002-10-08

Similar Documents

Publication Publication Date Title
EE200000468A (en) The compounds, their use and the pharmaceutical composition
FI991485A (en) New pharmaceutical composition
NO20015175L (en) Pharmaceutical composition
EE200200175A (en) Substituted 2-Thio-3,5-Dicyano-4-aryl-6-aminopyridines and their Uses
EE200100391A (en) Peptidyl-heterocyclic ketones, their use and pharmaceutical composition
EE200100684A (en) Indalyl-substituted benzenecarboxamides, process for their preparation, use and pharmaceutical compositions
EE200300145A (en) Aza and polyazanaphthalenylcarboxamides and pharmaceutical composition
ID27415A (en) PHARMACEUTICAL COMPOSITION
EE200200487A (en) Azetidine derivatives, processes for their preparation and pharmaceutical composition
NO20005913L (en) Medicinal Composition
EE200200251A (en) Novel N-azabicycloamide derivatives and their use
EE200100594A (en) Novel pharmaceutical compositions based on anticholinergic compounds and β-mimetics
EE05169B1 (en) Substituted oxazolidinones and their uses
PT1242087E (en) PHARMACEUTICAL COMPOSITIONS
EE05475B1 (en) Superantigen Conjugate, Conjugate Use, and Conjugate Containing Pharmaceutical Composition
ID29262A (en) PHARMACEUTICAL COMPOSITION
ID29089A (en) MOKSIFLOXASIN PHARMACEUTICAL PROPERTIES
EE200000621A (en) Anti-picornaviral compounds, their preparation and use
EE04497B1 (en) Pyridopyranoazepine derivatives, their preparation and therapeutic use
EE200200342A (en) Substituted 8-arylquinolines, their use, pharmaceutical composition and precursor compound
ID27201A (en) PHARMACEUTICAL COMPOSITION
NO20022606D0 (en) Pharmaceutical combinations
PT1239832E (en) PHARMACEUTICAL COMPOSITIONS
EE03996B1 (en) Pharmaceutical compositions, process for their preparation and use
FI4488U1 (en) Pharmaceutical composition

Legal Events

Date Code Title Description
GB1A Change in the ownership or in the address of the owner
HC1A Change of owner name
KB4A Valid patent at the end of a year

Effective date: 20081231

KB4A Valid patent at the end of a year

Effective date: 20101231

MM4A Lapsed by not paying the annual fees

Effective date: 20101101