BR0015161A - ácido nucleico, métodos para a triagem de bancos, para a identificação de um ácido nucleico e de sequência genÈmica, para produção de um polipeptìdeo recombinante, para a detecção e/ou a purificação de um polipeptìdeo, para o diagnóstico de uma patologia e para a seleção de compostos quìmicos ou bioquìmicosm polipeptìdios, vetor, célula hospedeira, mamìfero exceto o homem, utilização de uma sequência de ácido nucleico e de polipeptìdeo, anticorpors mono - ou policlinais ,e, composto - Google Patents
ácido nucleico, métodos para a triagem de bancos, para a identificação de um ácido nucleico e de sequência genÈmica, para produção de um polipeptìdeo recombinante, para a detecção e/ou a purificação de um polipeptìdeo, para o diagnóstico de uma patologia e para a seleção de compostos quìmicos ou bioquìmicosm polipeptìdios, vetor, célula hospedeira, mamìfero exceto o homem, utilização de uma sequência de ácido nucleico e de polipeptìdeo, anticorpors mono - ou policlinais ,e, compostoInfo
- Publication number
- BR0015161A BR0015161A BR0015161-0A BR0015161A BR0015161A BR 0015161 A BR0015161 A BR 0015161A BR 0015161 A BR0015161 A BR 0015161A BR 0015161 A BR0015161 A BR 0015161A
- Authority
- BR
- Brazil
- Prior art keywords
- nucleic acid
- polypeptide
- sequence
- methods
- identification
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title abstract 9
- 102000039446 nucleic acids Human genes 0.000 title abstract 9
- 150000007523 nucleic acids Chemical class 0.000 title abstract 9
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 150000001875 compounds Chemical class 0.000 title abstract 5
- 239000013598 vector Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000000126 substance Substances 0.000 title abstract 3
- 238000001514 detection method Methods 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 230000007170 pathology Effects 0.000 title abstract 2
- 238000000746 purification Methods 0.000 title abstract 2
- 238000012216 screening Methods 0.000 title abstract 2
- 241000124008 Mammalia Species 0.000 title 1
- 210000004027 cell Anatomy 0.000 abstract 2
- 238000012512 characterization method Methods 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
"áCIDO NUCLEICO, MéTODOS PARA A TRIAGEM DE BANCOS, PARA A IDENTIFICAçãO DE UM áCIDO NUCLEICO E DE SEQuêNCIA GENÈMICA, PARA PRODUçãO DE UM POLIPEPTìDEO RECOMBINANTE, PARA A DETECçãO E/OU A PURIFICAçãO DE UM POLIPEPTìDEO, PARA O DIAGNóSTICO DE UMA PATOLOGIA E PARA A SELEçãO DE COMPOSTOS QUìMICOS OU BIOQUìMICOS, POLIPEPTìDEO, VETOR, CéLULA HOSPEDEIRA, MAMìFERO EXCETO O HOMEM, UTILIZAçõES DE UMA SEQuêNCIA DE áCIDO NUCLEICO, DE áCIDO NUCLEICO E DE POLIPEPTìDEO, ANTICORPOS MONO- OU POLICLONAIS, E, COMPOSTO". A invenção refere-se à identificação e a caracterização de um novo gene expresso nas células tumorais e implicado na regulagem da resposta imune, a clonagem e a caracterização de seu cDNA, assim como os polipeptídeos correspondentes. A invenção refere-se igualmente a vetores contendo um ácido nucleico codificando para este gene, células transformadas por tais vetores, assim como os métodos de diagnóstico e métodos de seleção de um composto químico ou bioquímico capaz de interagir diretamente ou indiretamente com um ácido nucleico ou polipeptídeo de acordo com a invenção. A invenção refere-se, por outro lado, aos compostos para o tratamento de patologias imunes, notadamente as doenças autoimunes e o câncer.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9913629A FR2800388A1 (fr) | 1999-10-29 | 1999-10-29 | Clonage, expression et caracterisation d'un gene exprime dans des cellules tumorales et implique dans la regulation de la reponse immune |
| PCT/FR2000/003032 WO2001031003A1 (fr) | 1999-10-29 | 2000-10-30 | Clonage, expression et caracterisation d'un gene exprime dans des cellules tumorales et implique dans la regulation de la reponse immune |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0015161A true BR0015161A (pt) | 2002-07-09 |
Family
ID=9551565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0015161-0A BR0015161A (pt) | 1999-10-29 | 2000-10-30 | ácido nucleico, métodos para a triagem de bancos, para a identificação de um ácido nucleico e de sequência genÈmica, para produção de um polipeptìdeo recombinante, para a detecção e/ou a purificação de um polipeptìdeo, para o diagnóstico de uma patologia e para a seleção de compostos quìmicos ou bioquìmicosm polipeptìdios, vetor, célula hospedeira, mamìfero exceto o homem, utilização de uma sequência de ácido nucleico e de polipeptìdeo, anticorpors mono - ou policlinais ,e, composto |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP1226248A1 (pt) |
| JP (1) | JP2003516126A (pt) |
| CN (1) | CN1391608A (pt) |
| AU (1) | AU1284801A (pt) |
| BR (1) | BR0015161A (pt) |
| CA (1) | CA2389522A1 (pt) |
| FR (1) | FR2800388A1 (pt) |
| MX (1) | MXPA02004297A (pt) |
| WO (1) | WO2001031003A1 (pt) |
| ZA (1) | ZA200203340B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6951738B2 (en) | 1999-07-16 | 2005-10-04 | Human Genome Sciences, Inc. | Human tumor necrosis factor receptors TR13 and TR14 |
| JP2003252801A (ja) * | 2002-02-27 | 2003-09-10 | Japan Science & Technology Corp | 下垂体特異的遺伝子の使用法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2267192T3 (es) * | 1997-08-01 | 2007-03-01 | Serono Genetics Institute S.A. | Ests 5' para proteinas secretadas no especificas de tejido. |
| JP2001512013A (ja) * | 1997-08-01 | 2001-08-21 | ジェンセット | 前立腺に発現される分泌タンパク質の５’ｅｓｔ |
| DE19817948A1 (de) * | 1998-04-17 | 1999-10-21 | Metagen Gesellschaft Fuer Genomforschung Mbh | Menschliche Nukleinsäuresequenzen aus Endometrium-Tumor |
| KR20020008134A (ko) * | 1999-03-26 | 2002-01-29 | 장 스테판느 | 화합물 |
| WO2001002568A2 (en) * | 1999-07-02 | 2001-01-11 | Chiron Corporation | Human genes and gene expression products |
-
1999
- 1999-10-29 FR FR9913629A patent/FR2800388A1/fr active Pending
-
2000
- 2000-10-30 EP EP00974612A patent/EP1226248A1/fr not_active Withdrawn
- 2000-10-30 JP JP2001533984A patent/JP2003516126A/ja active Pending
- 2000-10-30 MX MXPA02004297A patent/MXPA02004297A/es unknown
- 2000-10-30 CN CN00816059A patent/CN1391608A/zh active Pending
- 2000-10-30 BR BR0015161-0A patent/BR0015161A/pt not_active Application Discontinuation
- 2000-10-30 AU AU12848/01A patent/AU1284801A/en not_active Abandoned
- 2000-10-30 WO PCT/FR2000/003032 patent/WO2001031003A1/fr not_active Application Discontinuation
- 2000-10-30 CA CA002389522A patent/CA2389522A1/fr not_active Abandoned
-
2002
- 2002-04-26 ZA ZA200203340A patent/ZA200203340B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2001031003A1 (fr) | 2001-05-03 |
| CN1391608A (zh) | 2003-01-15 |
| JP2003516126A (ja) | 2003-05-13 |
| AU1284801A (en) | 2001-05-08 |
| WO2001031003B1 (fr) | 2001-10-11 |
| EP1226248A1 (fr) | 2002-07-31 |
| MXPA02004297A (es) | 2002-10-31 |
| CA2389522A1 (fr) | 2001-05-03 |
| ZA200203340B (en) | 2002-12-11 |
| FR2800388A1 (fr) | 2001-05-04 |
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| BR0015161A (pt) | ácido nucleico, métodos para a triagem de bancos, para a identificação de um ácido nucleico e de sequência genÈmica, para produção de um polipeptìdeo recombinante, para a detecção e/ou a purificação de um polipeptìdeo, para o diagnóstico de uma patologia e para a seleção de compostos quìmicos ou bioquìmicosm polipeptìdios, vetor, célula hospedeira, mamìfero exceto o homem, utilização de uma sequência de ácido nucleico e de polipeptìdeo, anticorpors mono - ou policlinais ,e, composto | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |