BR0014666A - Vacina - Google Patents
VacinaInfo
- Publication number
- BR0014666A BR0014666A BR0014666-8A BR0014666A BR0014666A BR 0014666 A BR0014666 A BR 0014666A BR 0014666 A BR0014666 A BR 0014666A BR 0014666 A BR0014666 A BR 0014666A
- Authority
- BR
- Brazil
- Prior art keywords
- oligo
- vehicle
- polynucleotide
- development
- papilloma virus
- Prior art date
Links
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 108091034117 Oligonucleotide Proteins 0.000 abstract 3
- 108091033319 polynucleotide Proteins 0.000 abstract 3
- 102000040430 polynucleotide Human genes 0.000 abstract 3
- 239000002157 polynucleotide Substances 0.000 abstract 3
- 208000015181 infectious disease Diseases 0.000 abstract 2
- 101710121996 Hexon protein p72 Proteins 0.000 abstract 1
- 241000701806 Human papillomavirus Species 0.000 abstract 1
- 108700005307 Human papillomavirus HPV L1 Proteins 0.000 abstract 1
- 101710125418 Major capsid protein Proteins 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 238000002255 vaccination Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C07K14/01—DNA viruses
- C07K14/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/04—Drugs for disorders of the respiratory system for throat disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6075—Viral proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Otolaryngology (AREA)
Abstract
Patente de Invenção: "VACINA". A invenção refere-se a um veículo para introdução de uma substância em células, compreendendo uma proteína de capsídeo principal L1 do vírus do papiloma humano (proteína HPV-L1) que fora intencionalmente modificada para remover epítopo(s) de tipo(s) específico(s) causando a produção de anticorpos neutralizantes. A invenção também inclui um oligo ou polinucleotídeo codificando o referido veículo, vacinas compreendendo o referido veículo ou o referido oligo ou polinucleotídeo, bem como métodos de uso do carregador ou do oligo ou polinucleotídeo na vacinação contra infecções pelo vírus do papiloma humano, ou contra o desenvolvimento de conseq³ências de tal infecção, ou contra o desenvolvimento de certos cânceres.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9903534A SE514982C2 (sv) | 1999-09-30 | 1999-09-30 | Bärare innehållande ett huvudkapsidprotein L1 från humant papillomavirus samt dess användning |
PCT/SE2000/001808 WO2001023422A1 (en) | 1999-09-30 | 2000-09-19 | Vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0014666A true BR0014666A (pt) | 2002-06-18 |
Family
ID=20417209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0014666-8A BR0014666A (pt) | 1999-09-30 | 2000-09-19 | Vacina |
Country Status (25)
Country | Link |
---|---|
EP (1) | EP1222200B1 (pt) |
JP (1) | JP2003510064A (pt) |
KR (1) | KR20020047195A (pt) |
CN (1) | CN1373771A (pt) |
AT (1) | ATE313559T1 (pt) |
AU (1) | AU771481B2 (pt) |
BR (1) | BR0014666A (pt) |
CA (1) | CA2384723A1 (pt) |
CZ (1) | CZ20021023A3 (pt) |
DE (1) | DE60025016D1 (pt) |
EE (1) | EE200200157A (pt) |
HR (1) | HRP20020092A2 (pt) |
HU (1) | HUP0202770A3 (pt) |
IL (1) | IL148741A0 (pt) |
MX (1) | MXPA02003328A (pt) |
NO (1) | NO20020615L (pt) |
NZ (1) | NZ516725A (pt) |
PL (1) | PL355012A1 (pt) |
RU (1) | RU2002111554A (pt) |
SE (1) | SE514982C2 (pt) |
SK (1) | SK4222002A3 (pt) |
TR (1) | TR200200802T2 (pt) |
WO (1) | WO2001023422A1 (pt) |
YU (1) | YU22202A (pt) |
ZA (1) | ZA200200886B (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY139500A (en) * | 2003-11-12 | 2009-10-30 | Merck Sharp & Dohme | Optimized expression of hpv 58 l1 in yeast |
TWI349036B (en) * | 2004-03-24 | 2011-09-21 | Merck Sharp & Dohme | Optimized expression of hpv 52 l1 in yeast |
DE102004036913A1 (de) * | 2004-07-16 | 2006-02-09 | Responsif Gmbh | Verwendung von Pentameren zur Herstellung eines Medikaments |
CN1796403B (zh) * | 2004-12-22 | 2010-04-28 | 三峡大学 | 用于多型人乳头瘤病毒感染防治的多肽和疫苗 |
CN100392084C (zh) * | 2006-03-13 | 2008-06-04 | 曾毅 | 含密码子优化型hpv16l1基因的重组腺病毒 |
CN101914139B (zh) * | 2010-07-16 | 2012-11-21 | 四川大学 | 人类乳头瘤病毒(hpv)衣壳蛋白l1多肽及其制备与应用 |
MX2019015769A (es) | 2017-06-23 | 2020-08-03 | Verimmune Inc | Partículas tipo virus quiméricas y usos de estas como redireccionadores de respuestas inmunitarias específicos para el antígeno. |
CA3125184A1 (en) | 2018-12-27 | 2020-07-02 | Verimmune Inc. | Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors |
EP3920967A4 (en) * | 2019-02-08 | 2023-01-18 | Rensselaer Polytechnic Institute | CONTRACEPTIVE VACCINE BASED ON SPER-ASSOCIATED PROTEIN CATSPER |
KR20230129379A (ko) | 2020-10-19 | 2023-09-08 | 버이뮨 아이엔씨. | 바이러스에 영향받은 조성물 및 암 치료를 위해 이를 사용하여 기존 면역 반응을 재지향시키는 방법 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU4270196A (en) * | 1994-10-07 | 1996-05-02 | Lutz Gissmann | Papilloma virus-like particles, fusion proteins and process for producing the same |
FR2768749A1 (fr) * | 1997-09-22 | 1999-03-26 | Inst Nat Sante Rech Med | Virus artificiels derives de papillomavirus, et leurs utilisations, notamment en therapie genique |
DE19812941A1 (de) * | 1998-03-24 | 1999-10-07 | Medigene Ag | Arzneimittel zur Vermeidung oder Behandlung von Papillomavirusspezifischem Tumor |
-
1999
- 1999-09-30 SE SE9903534A patent/SE514982C2/sv not_active IP Right Cessation
-
2000
- 2000-09-19 IL IL14874100A patent/IL148741A0/xx unknown
- 2000-09-19 SK SK422-2002A patent/SK4222002A3/sk unknown
- 2000-09-19 HU HU0202770A patent/HUP0202770A3/hu unknown
- 2000-09-19 WO PCT/SE2000/001808 patent/WO2001023422A1/en active IP Right Grant
- 2000-09-19 DE DE60025016T patent/DE60025016D1/de not_active Expired - Lifetime
- 2000-09-19 YU YU22202A patent/YU22202A/sh unknown
- 2000-09-19 EE EEP200200157A patent/EE200200157A/xx unknown
- 2000-09-19 RU RU2002111554/13A patent/RU2002111554A/ru unknown
- 2000-09-19 NZ NZ516725A patent/NZ516725A/xx unknown
- 2000-09-19 PL PL00355012A patent/PL355012A1/xx not_active Application Discontinuation
- 2000-09-19 TR TR2002/00802T patent/TR200200802T2/xx unknown
- 2000-09-19 BR BR0014666-8A patent/BR0014666A/pt not_active IP Right Cessation
- 2000-09-19 AU AU76951/00A patent/AU771481B2/en not_active Ceased
- 2000-09-19 KR KR1020027004124A patent/KR20020047195A/ko not_active Application Discontinuation
- 2000-09-19 AT AT00966633T patent/ATE313559T1/de not_active IP Right Cessation
- 2000-09-19 JP JP2001526572A patent/JP2003510064A/ja active Pending
- 2000-09-19 MX MXPA02003328A patent/MXPA02003328A/es unknown
- 2000-09-19 CA CA002384723A patent/CA2384723A1/en not_active Abandoned
- 2000-09-19 CZ CZ20021023A patent/CZ20021023A3/cs unknown
- 2000-09-19 CN CN00812618A patent/CN1373771A/zh active Pending
- 2000-09-19 EP EP00966633A patent/EP1222200B1/en not_active Expired - Lifetime
-
2002
- 2002-01-29 HR HR20020092A patent/HRP20020092A2/hr not_active Application Discontinuation
- 2002-01-31 ZA ZA200200886A patent/ZA200200886B/en unknown
- 2002-02-08 NO NO20020615A patent/NO20020615L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CN1373771A (zh) | 2002-10-09 |
EE200200157A (et) | 2003-04-15 |
YU22202A (sh) | 2005-06-10 |
AU771481B2 (en) | 2004-03-25 |
WO2001023422A1 (en) | 2001-04-05 |
TR200200802T2 (tr) | 2002-09-23 |
HUP0202770A3 (en) | 2004-07-28 |
EP1222200A1 (en) | 2002-07-17 |
SE9903534D0 (sv) | 1999-09-30 |
HRP20020092A2 (en) | 2003-06-30 |
ATE313559T1 (de) | 2006-01-15 |
EP1222200B1 (en) | 2005-12-21 |
IL148741A0 (en) | 2002-09-12 |
PL355012A1 (en) | 2004-03-22 |
KR20020047195A (ko) | 2002-06-21 |
NO20020615L (no) | 2002-05-29 |
ZA200200886B (en) | 2003-03-26 |
NZ516725A (en) | 2003-03-28 |
JP2003510064A (ja) | 2003-03-18 |
SE514982C2 (sv) | 2001-05-28 |
NO20020615D0 (no) | 2002-02-08 |
SK4222002A3 (en) | 2002-10-08 |
SE9903534L (sv) | 2001-03-31 |
DE60025016D1 (de) | 2006-01-26 |
CZ20021023A3 (cs) | 2002-07-17 |
AU7695100A (en) | 2001-04-30 |
RU2002111554A (ru) | 2004-03-27 |
MXPA02003328A (es) | 2004-09-10 |
HUP0202770A2 (hu) | 2002-12-28 |
CA2384723A1 (en) | 2001-04-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A,7A E 8A ANUIDADE. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |