BR0014183A - Composições farmaceuticas e metodos de uso de proteìna relacionada frizzled secretada - Google Patents
Composições farmaceuticas e metodos de uso de proteìna relacionada frizzled secretadaInfo
- Publication number
- BR0014183A BR0014183A BR0014183-6A BR0014183A BR0014183A BR 0014183 A BR0014183 A BR 0014183A BR 0014183 A BR0014183 A BR 0014183A BR 0014183 A BR0014183 A BR 0014183A
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- pharmaceutical compositions
- secreted
- related protein
- sfrps
- Prior art date
Links
- 108010020277 WD repeat containing planar cell polarity effector Proteins 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 102100030053 Secreted frizzled-related protein 3 Human genes 0.000 title abstract 2
- 210000000963 osteoblast Anatomy 0.000 abstract 2
- 208000005623 Carcinogenesis Diseases 0.000 abstract 1
- 101000864743 Homo sapiens Secreted frizzled-related protein 1 Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 102100030058 Secreted frizzled-related protein 1 Human genes 0.000 abstract 1
- 230000031018 biological processes and functions Effects 0.000 abstract 1
- 230000036952 cancer formation Effects 0.000 abstract 1
- 231100000504 carcinogenesis Toxicity 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000013020 embryo development Effects 0.000 abstract 1
- 239000003102 growth factor Substances 0.000 abstract 1
- 210000004409 osteocyte Anatomy 0.000 abstract 1
- 230000002188 osteogenic effect Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000026011 regulation of ossification Effects 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0275—Genetically modified vertebrates, e.g. transgenic
- A01K67/0276—Knock-out vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Environmental Sciences (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Biodiversity & Conservation Biology (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- Psychiatry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Animal Husbandry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39483299A | 1999-09-13 | 1999-09-13 | |
| PCT/US2000/025035 WO2001019855A2 (en) | 1999-09-13 | 2000-09-13 | Pharmaceutical compositions and methods of using secreted frizzled related protein |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0014183A true BR0014183A (pt) | 2002-05-14 |
Family
ID=23560597
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0014183-6A BR0014183A (pt) | 1999-09-13 | 2000-09-13 | Composições farmaceuticas e metodos de uso de proteìna relacionada frizzled secretada |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1212355A2 (cs) |
| JP (1) | JP2003512304A (cs) |
| CN (2) | CN102988957A (cs) |
| AU (1) | AU7131200A (cs) |
| BR (1) | BR0014183A (cs) |
| CA (1) | CA2383360A1 (cs) |
| CZ (1) | CZ2002903A3 (cs) |
| IL (1) | IL148421A0 (cs) |
| MX (1) | MXPA02002624A (cs) |
| NZ (1) | NZ529560A (cs) |
| WO (1) | WO2001019855A2 (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA02008487A (es) | 2000-02-29 | 2002-12-13 | Alcon Lab Inc | Diagnosticos y terapeutica del glaucoma. |
| US6600018B1 (en) | 2000-04-10 | 2003-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Secreted frizzled related protein, sFRP, fragments and methods of use thereof |
| EP1318840A2 (en) * | 2000-07-19 | 2003-06-18 | Genzyme Corporation | PHOSPHATONIN-RELATED GENE AND i METHODS OF USE THEREOF /i |
| JP4029041B2 (ja) | 2001-01-10 | 2008-01-09 | アメリカ合衆国 | ｓＦＲＰおよびｓＦＲＰと相互作用するペプチドモチーフならびにそれらの使用法 |
| EP1222933A1 (en) * | 2001-01-15 | 2002-07-17 | Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum | Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway |
| WO2002081745A2 (en) * | 2001-04-05 | 2002-10-17 | Proskelia Pharmaceuticals | Genes involved in osteogenesis, and methods of use |
| AU2002308557A1 (en) | 2001-05-01 | 2002-11-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
| US7713526B2 (en) | 2001-05-01 | 2010-05-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
| GB0111004D0 (en) * | 2001-05-04 | 2001-06-27 | Univ Sheffield | Screening method |
| CA2467258A1 (en) * | 2001-11-15 | 2003-05-22 | Kyowa Hakko Kogyo Co., Ltd. | Agent for inducing embryonic stem cell to ectodermal cell, method for obtaining the same and use of the same. |
| ES2362681T3 (es) * | 2002-12-05 | 2011-07-11 | The Board Of Trustees Of The University Of Arkansas | Determinantes moleculares de la osteopatía por mieloma y uso de los mismos. |
| WO2004090161A1 (en) * | 2003-04-14 | 2004-10-21 | Novartis Ag | Gene expression associated with osteoblast differentiation |
| CN104726460A (zh) * | 2013-12-22 | 2015-06-24 | 上海交通大学医学院 | 蛋白sFRP-5在治疗银屑病的药物中的应用 |
| CN107073117A (zh) * | 2014-08-26 | 2017-08-18 | 埃塔根有限公司 | 用于识别wls蛋白特定基序的抗体和含有其的药物组合物 |
| EP3696192A1 (en) * | 2019-02-15 | 2020-08-19 | Consejo Superior De Investigaciones Científicas | Therapeutic target and monoclonal antibodies against it for the diagnosis and treatment of alzheimer´s disease |
| CN110361541A (zh) * | 2019-07-23 | 2019-10-22 | 上海交通大学医学院附属瑞金医院 | sFRP2和PCPE1作为联合靶点在制备纤维化疾病药物中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5681701A (en) * | 1993-07-12 | 1997-10-28 | Mayo Foundation For Medical Education And Research | Immortalized human fetal osteoblastic cells |
| CN1151744A (zh) * | 1994-07-04 | 1997-06-11 | 武田药品工业株式会社 | 膦酸化合物及其制备和应用 |
| WO1998016641A1 (en) * | 1996-10-11 | 1998-04-23 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Isolation and method of using tissue growth-inducing frzb protein |
| AU7704498A (en) * | 1997-05-29 | 1998-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Human frp and fragments thereof including methods for using them |
-
2000
- 2000-09-13 CA CA002383360A patent/CA2383360A1/en not_active Abandoned
- 2000-09-13 CN CN200910208473XA patent/CN102988957A/zh active Pending
- 2000-09-13 NZ NZ529560A patent/NZ529560A/en not_active IP Right Cessation
- 2000-09-13 CZ CZ2002903A patent/CZ2002903A3/cs unknown
- 2000-09-13 IL IL14842100A patent/IL148421A0/xx unknown
- 2000-09-13 BR BR0014183-6A patent/BR0014183A/pt not_active IP Right Cessation
- 2000-09-13 EP EP00960097A patent/EP1212355A2/en not_active Withdrawn
- 2000-09-13 MX MXPA02002624A patent/MXPA02002624A/es active IP Right Grant
- 2000-09-13 WO PCT/US2000/025035 patent/WO2001019855A2/en active Application Filing
- 2000-09-13 JP JP2001523632A patent/JP2003512304A/ja active Pending
- 2000-09-13 AU AU71312/00A patent/AU7131200A/en not_active Abandoned
- 2000-09-13 CN CN00815431A patent/CN1387537A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| IL148421A0 (en) | 2002-09-12 |
| EP1212355A2 (en) | 2002-06-12 |
| CN1387537A (zh) | 2002-12-25 |
| AU7131200A (en) | 2001-04-17 |
| JP2003512304A (ja) | 2003-04-02 |
| CZ2002903A3 (cs) | 2002-07-17 |
| MXPA02002624A (es) | 2002-07-30 |
| NZ529560A (en) | 2005-05-27 |
| CN102988957A (zh) | 2013-03-27 |
| WO2001019855A3 (en) | 2002-01-24 |
| WO2001019855A2 (en) | 2001-03-22 |
| CA2383360A1 (en) | 2001-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 12A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2166 DE 10/07/2012. |