CN102988957A - 应用分泌型卷曲相关蛋白的药用组合物和方法 - Google Patents
应用分泌型卷曲相关蛋白的药用组合物和方法 Download PDFInfo
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- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
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| PL208368B1 (pl) | 2000-02-29 | 2011-04-29 | Alcon Inc | Sposób diagnozowania jaskry |
| US6600018B1 (en) | 2000-04-10 | 2003-07-29 | The United States Of America As Represented By The Department Of Health And Human Services | Secreted frizzled related protein, sFRP, fragments and methods of use thereof |
| AU2001280680A1 (en) * | 2000-07-19 | 2002-01-30 | Genzyme Corporation | Phosphatonin-related gene and methods of use thereof |
| PT1387854E (pt) | 2001-01-10 | 2012-06-26 | Us Dept Health | Sfrp e motivos de peptídeos que interagem com a sfrp e respectivos métodos de utilização |
| EP1222933A1 (en) * | 2001-01-15 | 2002-07-17 | Academisch Ziekenhuis Leiden h.o.d.n., Leids Universitair Medisch Centrum | Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway |
| WO2002081745A2 (en) * | 2001-04-05 | 2002-10-17 | Proskelia Pharmaceuticals | Genes involved in osteogenesis, and methods of use |
| AU2002308557A1 (en) | 2001-05-01 | 2002-11-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
| US7713526B2 (en) | 2001-05-01 | 2010-05-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
| GB0111004D0 (en) * | 2001-05-04 | 2001-06-27 | Univ Sheffield | Screening method |
| US20060281179A1 (en) * | 2001-11-15 | 2006-12-14 | Yoshiki Sasai | Inducer for differentiation of embryo stem cells into ectodermal cells method of obtaining the same and use thereof |
| EP1913952B1 (en) * | 2002-12-05 | 2011-03-09 | The Board Of Trustees Of The University Of Arkansas | Molecular determinants of myeloma bone disease and uses thereof |
| EP1616026A1 (en) * | 2003-04-14 | 2006-01-18 | Novartis AG | Gene expression associated with osteoblast differentiation |
| CN104726460A (zh) * | 2013-12-22 | 2015-06-24 | 上海交通大学医学院 | 蛋白sFRP-5在治疗银屑病的药物中的应用 |
| KR101835939B1 (ko) * | 2014-08-26 | 2018-03-23 | 연세대학교 산학협력단 | Wls 단백질의 특정 모티프를 인지하는 항체 및 이를 포함하는 약제학적 조성물 |
| EP3696192A1 (en) * | 2019-02-15 | 2020-08-19 | Consejo Superior De Investigaciones Científicas | Therapeutic target and monoclonal antibodies against it for the diagnosis and treatment of alzheimer´s disease |
| CN110361541A (zh) * | 2019-07-23 | 2019-10-22 | 上海交通大学医学院附属瑞金医院 | sFRP2和PCPE1作为联合靶点在制备纤维化疾病药物中的应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995002687A1 (en) * | 1993-07-12 | 1995-01-26 | Mayo Foundation For Medical Education And Research | Immortalized human fetal osteoblastic cells |
| CN1151744A (zh) * | 1994-07-04 | 1997-06-11 | 武田药品工业株式会社 | 膦酸化合物及其制备和应用 |
| WO1998016641A1 (en) * | 1996-10-11 | 1998-04-23 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Isolation and method of using tissue growth-inducing frzb protein |
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| AU7704498A (en) * | 1997-05-29 | 1998-12-30 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Human frp and fragments thereof including methods for using them |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995002687A1 (en) * | 1993-07-12 | 1995-01-26 | Mayo Foundation For Medical Education And Research | Immortalized human fetal osteoblastic cells |
| CN1151744A (zh) * | 1994-07-04 | 1997-06-11 | 武田药品工业株式会社 | 膦酸化合物及其制备和应用 |
| WO1998016641A1 (en) * | 1996-10-11 | 1998-04-23 | The Government Of The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Isolation and method of using tissue growth-inducing frzb protein |
Non-Patent Citations (1)
| Title |
|---|
| HOVSEP S. MELKONYAN ET AL.: "SARPs: A family of secreted apoptosis-related proteins", 《PROC. NATL. ACAD. SCI. USA》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2002903A3 (cs) | 2002-07-17 |
| JP2003512304A (ja) | 2003-04-02 |
| WO2001019855A2 (en) | 2001-03-22 |
| BR0014183A (pt) | 2002-05-14 |
| NZ529560A (en) | 2005-05-27 |
| EP1212355A2 (en) | 2002-06-12 |
| IL148421A0 (en) | 2002-09-12 |
| WO2001019855A3 (en) | 2002-01-24 |
| CN1387537A (zh) | 2002-12-25 |
| AU7131200A (en) | 2001-04-17 |
| MXPA02002624A (es) | 2002-07-30 |
| CA2383360A1 (en) | 2001-03-22 |
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