BR0013582A - Agonistas retinóides seletivos para rar - Google Patents

Agonistas retinóides seletivos para rar

Info

Publication number
BR0013582A
BR0013582A BR0013582-8A BR0013582A BR0013582A BR 0013582 A BR0013582 A BR 0013582A BR 0013582 A BR0013582 A BR 0013582A BR 0013582 A BR0013582 A BR 0013582A
Authority
BR
Brazil
Prior art keywords
rar
selective
retinoid agonists
selective retinoid
agonists
Prior art date
Application number
BR0013582-8A
Other languages
English (en)
Inventor
Paula Nanette Belloni
Peter Mohr
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of BR0013582A publication Critical patent/BR0013582A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/20—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 hydrogenated in the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

Patente de Invenção: "AGONISTAS RETINóIDES SELETIVOS PARA RAR". Esta invenção refere-se a novos agonistas de retinóides seletivos para RAR de fórmula (I) em que os símbolo são como definidos no relatório descritivo aos seus sais farmaceuticamente aceitáveis, aos seus isómeros individuais ou a uma mistura racêmica ou não-racêmica; a composições farmacêuticas contendo os mesmos e aos processos para a utilização dos mesmos como agentes terapêuticos.
BR0013582-8A 1999-08-25 2000-08-18 Agonistas retinóides seletivos para rar BR0013582A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99116603 1999-08-25
PCT/EP2000/008065 WO2001014360A2 (en) 1999-08-25 2000-08-18 Benzopyrans and benzothiopyrans as rar selective retinoid agonists

Publications (1)

Publication Number Publication Date
BR0013582A true BR0013582A (pt) 2002-05-07

Family

ID=8238844

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0013582-8A BR0013582A (pt) 1999-08-25 2000-08-18 Agonistas retinóides seletivos para rar

Country Status (18)

Country Link
US (1) US6479670B1 (pt)
EP (1) EP1212316B1 (pt)
JP (1) JP3795394B2 (pt)
KR (1) KR100470500B1 (pt)
CN (1) CN1151144C (pt)
AR (1) AR025351A1 (pt)
AT (1) ATE252093T1 (pt)
AU (1) AU769784B2 (pt)
BR (1) BR0013582A (pt)
CA (1) CA2382527A1 (pt)
DE (1) DE60005980T2 (pt)
DK (1) DK1212316T3 (pt)
ES (1) ES2207548T3 (pt)
MX (1) MXPA02001939A (pt)
PT (1) PT1212316E (pt)
TR (1) TR200200473T2 (pt)
WO (1) WO2001014360A2 (pt)
ZA (1) ZA200200939B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4145200A (en) * 1999-05-07 2000-11-21 Takeda Chemical Industries Ltd. Cyclic compounds and uses thereof
JO2178B1 (en) * 1999-10-19 2003-04-23 اف . هوفمان لاروش ايه جي Treatment of invasive diseases, using selected anti-PAR materials
EP1241166A4 (en) * 1999-12-13 2003-04-16 Chugai Pharmaceutical Co Ltd 3-MEHTYL CHROMAN AND THIOCHROME DERIVATIVES
WO2003040127A1 (en) * 2001-11-02 2003-05-15 G.D. Searle Llc Novel mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (asbt) and taurocholate uptake
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
WO2004048391A1 (en) * 2002-11-25 2004-06-10 Amedis Pharmaceuticals Ltd. Silicon compounds to be used as ligands for retinoid receptors
ATE493091T1 (de) * 2004-03-30 2011-01-15 Proxy Biomedical Ltd Behandeltes chirurgisches mesh aus monofilen fasern
US9119777B2 (en) 2008-05-30 2015-09-01 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
US8415390B2 (en) 2008-05-30 2013-04-09 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
EP3039126B1 (en) 2013-08-26 2019-10-09 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Small molecule cellular reprogramming to generate neuronal cells
EP3348279B1 (en) * 2015-09-10 2021-08-04 National University Corporation Okayama University Medicinal composition for preventing or treating inflammatory respiratory disease
CN107176945B (zh) 2016-03-11 2021-06-08 中国科学院上海有机化学研究所 一种视黄酸类化合物、其制备方法、中间体及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5958954A (en) 1995-09-01 1999-09-28 Allergan Sales, Inc. Synthesis and use of retinoid compounds having negative hormone and/or antagonist activities

Also Published As

Publication number Publication date
KR100470500B1 (ko) 2005-02-07
DK1212316T3 (da) 2004-02-23
DE60005980T2 (de) 2004-08-12
AR025351A1 (es) 2002-11-20
PT1212316E (pt) 2004-02-27
US6479670B1 (en) 2002-11-12
CA2382527A1 (en) 2001-03-01
EP1212316A2 (en) 2002-06-12
WO2001014360A2 (en) 2001-03-01
ATE252093T1 (de) 2003-11-15
ZA200200939B (en) 2003-07-30
MXPA02001939A (es) 2002-08-20
EP1212316B1 (en) 2003-10-15
WO2001014360A3 (en) 2001-05-17
AU769784B2 (en) 2004-02-05
KR20020039335A (ko) 2002-05-25
ES2207548T3 (es) 2004-06-01
JP3795394B2 (ja) 2006-07-12
AU6997100A (en) 2001-03-19
TR200200473T2 (tr) 2002-05-21
CN1370156A (zh) 2002-09-18
DE60005980D1 (de) 2003-11-20
JP2003507465A (ja) 2003-02-25
CN1151144C (zh) 2004-05-26

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A E 9A ANUIDADES

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2008 DE 30/06/2009.