BR0010356A - Veìculo de droga para administração controlada de ingrediente ativo, preparado a partir de conjugados matriz lipìdica-droga (partìculas de ldc) - Google Patents
Veìculo de droga para administração controlada de ingrediente ativo, preparado a partir de conjugados matriz lipìdica-droga (partìculas de ldc)Info
- Publication number
- BR0010356A BR0010356A BR0010356-0A BR0010356A BR0010356A BR 0010356 A BR0010356 A BR 0010356A BR 0010356 A BR0010356 A BR 0010356A BR 0010356 A BR0010356 A BR 0010356A
- Authority
- BR
- Brazil
- Prior art keywords
- drug
- ldc
- prepared
- active ingredient
- lipid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Botany (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Patente de Invenção: "VEìCULO DE DROGA PARA ADMINISTRAçãO CONTROLADA DE INGREDIENTE ATIVO, PREPARADO A PARTIR DE CONJUGADOS MATRIZ LIPìDICA-DROGA (PARTìCULAS DE LDC)". A invenção refere-se a veículos de ingredientes ativos particulados que estão no estado agregado sólido à temperatura ambiente (20<198>C) e consistem em um conjugado lipídio-droga (LDC) puro ou uma mistura de vários LDCs como matriz de partículas, a ligação no LDC sendo efetuada por ligação covalente, interações eletrostáticas, momentos dipolares, forças de dispersão, interações iónicas, pontes de hidrogênio e/ou interações hidrófobas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19920908A DE19920908A1 (de) | 1999-05-07 | 1999-05-07 | Arzneistoffträger zur kontrollierten Wirkstoffapplikation hergestellt aus Lipidmatrix-Arzneistoffkonjugaten (LAK-Partikel) |
DE19964085A DE19964085A1 (de) | 1999-12-27 | 1999-12-27 | Arzneistoffträgr zur kontrollierten Wirkstoffapplikation hergestellt aus Lipidmatrix-Arzneistoffkonjugaten (LAK-Partikel) |
PCT/EP2000/004111 WO2000067800A2 (de) | 1999-05-07 | 2000-05-08 | Arzneistoffträger zur kontrollierten wirkstoffapplikation hergestellt aus lipidmatrix-arzneistoff-konjugaten (lak-partikel) |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0010356A true BR0010356A (pt) | 2002-02-13 |
Family
ID=26053253
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0010356-0A BR0010356A (pt) | 1999-05-07 | 2000-05-08 | Veìculo de droga para administração controlada de ingrediente ativo, preparado a partir de conjugados matriz lipìdica-droga (partìculas de ldc) |
Country Status (11)
Country | Link |
---|---|
US (1) | US6770299B1 (pt) |
EP (1) | EP1176984B1 (pt) |
JP (1) | JP2002544177A (pt) |
KR (1) | KR20020012215A (pt) |
AU (1) | AU4563100A (pt) |
BR (1) | BR0010356A (pt) |
CA (1) | CA2372461A1 (pt) |
DE (1) | DE50013950D1 (pt) |
MX (1) | MXPA01011347A (pt) |
TR (1) | TR200103187T2 (pt) |
WO (1) | WO2000067800A2 (pt) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20060097020A (ko) * | 2003-10-31 | 2006-09-13 | 테바 파마슈티컬 인더스트리즈 리미티드 | 약물 전달용 나노입자 |
KR20060123384A (ko) * | 2003-12-24 | 2006-12-01 | 가부시키가이샤 엘티티 바이오파마 | 약물을 함유하는 나노 입자 및 그 제조 방법, 그리고 당해나노 입자로 이루어지는 비경구 투여용 제제 |
US7282194B2 (en) * | 2004-10-05 | 2007-10-16 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
US20070254037A1 (en) * | 2004-12-15 | 2007-11-01 | Youri Popowski | Methods and Compositions for the Treatment of Cell Proliferation |
EP1674081A1 (de) * | 2004-12-23 | 2006-06-28 | KTB Tumorforschungsgesellschaft mbH | Herstellung von lipidbasierten Nanopartikeln unter Einsatz einer dualen asymmetrischen Zentrifuge |
CA2669392C (en) | 2006-11-17 | 2016-05-10 | Abbott Gmbh & Co. Kg | Nanocrystals for use in topical cosmetic formulations and method of production thereof |
GB0623838D0 (en) * | 2006-11-29 | 2007-01-10 | Malvern Cosmeceutics Ltd | Novel compositions |
US20090053268A1 (en) * | 2007-08-22 | 2009-02-26 | Depablo Juan J | Nanoparticle modified lubricants and waxes with enhanced properties |
US20090061009A1 (en) * | 2007-08-29 | 2009-03-05 | Joseph Schwarz | Composition and Method of Treatment of Bacterial Infections |
US8603999B2 (en) | 2008-12-05 | 2013-12-10 | Commonwealth Scientific And Industrial Research Organisation | Amphiphile prodrugs |
EP2229936B1 (en) * | 2009-03-09 | 2015-05-06 | PharmaSol GmbH | Nanonized testosterone formulations for improved bioavailability |
WO2012059936A1 (en) | 2010-11-03 | 2012-05-10 | Padma Venkitachalam Devarajan | Pharmaceutical compositions for colloidal drug delivery |
CN104127387A (zh) * | 2014-02-21 | 2014-11-05 | 杭州长典医药科技有限公司 | 奥美拉唑钠特种超细粉体冻干制剂及其制备方法 |
BE1023491B1 (nl) * | 2015-10-06 | 2017-04-06 | Nutri-Ad International Nv | Voedingsadditief voor gevogelte |
AU2020245715A1 (en) * | 2019-03-22 | 2021-08-19 | Integrated Nanotherapeutics Inc. | Lipid conjugate prepared from scaffold moiety |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5543390A (en) * | 1990-11-01 | 1996-08-06 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University | Covalent microparticle-drug conjugates for biological targeting |
US5554728A (en) * | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
US5907030A (en) * | 1995-01-25 | 1999-05-25 | University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
DE19745950A1 (de) * | 1997-10-17 | 1999-04-22 | Dds Drug Delivery Service Ges | Arzneistoffträgerpartikel für die gewebespezifische Arzneistoffapplikation |
-
2000
- 2000-05-08 EP EP00927163A patent/EP1176984B1/de not_active Expired - Lifetime
- 2000-05-08 AU AU45631/00A patent/AU4563100A/en not_active Abandoned
- 2000-05-08 DE DE50013950T patent/DE50013950D1/de not_active Expired - Lifetime
- 2000-05-08 TR TR2001/03187T patent/TR200103187T2/xx unknown
- 2000-05-08 US US09/959,706 patent/US6770299B1/en not_active Expired - Fee Related
- 2000-05-08 JP JP2000616825A patent/JP2002544177A/ja not_active Withdrawn
- 2000-05-08 KR KR1020017014236A patent/KR20020012215A/ko not_active Application Discontinuation
- 2000-05-08 CA CA002372461A patent/CA2372461A1/en not_active Abandoned
- 2000-05-08 BR BR0010356-0A patent/BR0010356A/pt not_active IP Right Cessation
- 2000-05-08 WO PCT/EP2000/004111 patent/WO2000067800A2/de active IP Right Grant
- 2000-05-08 MX MXPA01011347A patent/MXPA01011347A/es unknown
Also Published As
Publication number | Publication date |
---|---|
EP1176984A2 (de) | 2002-02-06 |
WO2000067800A3 (de) | 2001-05-10 |
JP2002544177A (ja) | 2002-12-24 |
AU4563100A (en) | 2000-11-21 |
TR200103187T2 (tr) | 2002-04-22 |
EP1176984B1 (de) | 2007-01-10 |
KR20020012215A (ko) | 2002-02-15 |
CA2372461A1 (en) | 2000-11-16 |
DE50013950D1 (de) | 2007-02-22 |
US6770299B1 (en) | 2004-08-03 |
WO2000067800A2 (de) | 2000-11-16 |
MXPA01011347A (es) | 2004-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0010356A (pt) | Veìculo de droga para administração controlada de ingrediente ativo, preparado a partir de conjugados matriz lipìdica-droga (partìculas de ldc) | |
BR9810945A (pt) | Formulações de agentes farmacológicos, métodos para sua preparação e métodos para uso das mesmas | |
DE69122828T2 (de) | Hydroxyapatit-antigen-konjugate und verfahren zur auslösung einer poly-ig-immunantwort | |
CA2267498A1 (en) | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof | |
WO2000071079A3 (en) | Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof | |
CA2294172C (en) | Pharmaceutical composition in form of solid lipidic microparticles suitable to parenteral administration | |
FI935314A0 (fi) | Farmaceutisk baerande | |
MXPA05003591A (es) | Materiales basados en ciclodextrina, composiciones y usos relacionados a los mismos. | |
BR0014271A (pt) | Composições antivirais | |
BR9802487A (pt) | Composicões de simeticona/fosfato de cálcio anídrico. | |
AU706584C (en) | Immunoglobulin variants | |
García-Fernández et al. | Targeting inflammasome by the inhibition of caspase-1 activity using capped mesoporous silica nanoparticles | |
CA2332007A1 (en) | Adenosine a3 receptor modulators | |
PT730443E (pt) | Suspensao de etabonato de loteprednol | |
BR0108461A (pt) | Composição cosmética de fase única transparente | |
A Stout | Recent advancements in carbon nanofiber and carbon nanotube applications in drug delivery and tissue engineering | |
DE102006011507A1 (de) | Wirkstoffbeladene Nanopartikel auf Basis hydrophiler Proteine | |
BR0015676A (pt) | Composição pesticida, método para controlar pestes, e, uso de uma composição de gel aerado estável em armazenamento | |
DK1551803T3 (da) | Azabicycloderivater som muskarine receptorantagonister | |
BR9812553A (pt) | Formulação medicamentosa com liberação de substância ativa controlada | |
DE50203850D1 (de) | Modifizierte Kolloide und deren Verwendung | |
CA2390107A1 (en) | Storage-stable aerated gel composition and a process for producing it | |
EP1186292A3 (de) | Feste Zubereitungen mit einer Multi-Kern Struktur | |
BR9711081A (pt) | Direcionamento de pró-drogas macromoleculares para linfócitos t. | |
EP2272504A3 (en) | Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 47/54 (2017.01), A61K 47/55 (2017.01) |