BR0009529A - Sequenciamento de polinucleotìdeos usando uma helicase - Google Patents

Sequenciamento de polinucleotìdeos usando uma helicase

Info

Publication number
BR0009529A
BR0009529A BR0009529-0A BR0009529A BR0009529A BR 0009529 A BR0009529 A BR 0009529A BR 0009529 A BR0009529 A BR 0009529A BR 0009529 A BR0009529 A BR 0009529A
Authority
BR
Brazil
Prior art keywords
helicase
sequencing
enzyme
polynucleotides
polynucleotide
Prior art date
Application number
BR0009529-0A
Other languages
English (en)
Inventor
Daniel Henry Densham
Original Assignee
Medical Biosystems Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medical Biosystems Ltd filed Critical Medical Biosystems Ltd
Publication of BR0009529A publication Critical patent/BR0009529A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54373Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/533Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isomerase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Patente de Invenção: "SEQuENCIAMENTO DE POLINUCLEOTìDEOS USANDO UMA HELICASE". Um processo para o seq³enciamento de um polinucleotídeo, compreendendo as etapas de (i) reação de um polinucleotídeo alvo com uma enzima de helicase / primase (que pode estar imobilizada), sob condições adequadas para a atividade da enzima; e (ii) detecção da interação entre a enzima e um nucleotídeo no alvo, por medição de radiação.
BR0009529-0A 1999-04-06 2000-04-06 Sequenciamento de polinucleotìdeos usando uma helicase BR0009529A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9907812.3A GB9907812D0 (en) 1999-04-06 1999-04-06 Sequencing
PCT/GB2000/001290 WO2000060114A2 (en) 1999-04-06 2000-04-06 Polynucleotide sequencing using a helicase

Publications (1)

Publication Number Publication Date
BR0009529A true BR0009529A (pt) 2002-01-29

Family

ID=10851007

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0009529-0A BR0009529A (pt) 1999-04-06 2000-04-06 Sequenciamento de polinucleotìdeos usando uma helicase

Country Status (14)

Country Link
US (1) US20080096206A1 (pt)
EP (1) EP1198590A2 (pt)
JP (1) JP2002540800A (pt)
KR (1) KR100846884B1 (pt)
CN (1) CN1201018C (pt)
AU (1) AU769140B2 (pt)
BR (1) BR0009529A (pt)
CA (1) CA2367277A1 (pt)
GB (1) GB9907812D0 (pt)
IL (2) IL145579A0 (pt)
IS (1) IS6089A (pt)
MX (1) MXPA01009997A (pt)
NZ (1) NZ514347A (pt)
WO (1) WO2000060114A2 (pt)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035012A2 (en) 1997-02-12 1998-08-13 Chan Eugene Y Methods and products for analyzing polymers
US7056661B2 (en) 1999-05-19 2006-06-06 Cornell Research Foundation, Inc. Method for sequencing nucleic acid molecules
US6927065B2 (en) 1999-08-13 2005-08-09 U.S. Genomics, Inc. Methods and apparatus for characterization of single polymers
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing
US6908736B1 (en) 1999-10-06 2005-06-21 Medical Biosystems, Ltd. DNA sequencing method
AU2001282881B2 (en) 2000-07-07 2007-06-14 Visigen Biotechnologies, Inc. Real-time sequence determination
WO2002044425A2 (en) 2000-12-01 2002-06-06 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
EP2801624B1 (en) 2001-03-16 2019-03-06 Singular Bio, Inc Arrays and methods of use
GB0112238D0 (en) 2001-05-18 2001-07-11 Medical Biosystems Ltd Sequencing method
US6956114B2 (en) 2001-10-30 2005-10-18 '454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
US6902921B2 (en) 2001-10-30 2005-06-07 454 Corporation Sulfurylase-luciferase fusion proteins and thermostable sulfurylase
WO2005003375A2 (en) 2003-01-29 2005-01-13 454 Corporation Methods of amplifying and sequencing nucleic acids
JP2007518107A (ja) 2004-01-13 2007-07-05 ユー.エス. ジェノミクス, インコーポレイテッド ポリマーを使用する溶液中の分析物の検出および定量化
US7595160B2 (en) 2004-01-13 2009-09-29 U.S. Genomics, Inc. Analyte detection using barcoded polymers
GB0413082D0 (en) 2004-06-11 2004-07-14 Medical Biosystems Ltd Method
US7170050B2 (en) 2004-09-17 2007-01-30 Pacific Biosciences Of California, Inc. Apparatus and methods for optical analysis of molecules
EP2274449B1 (en) 2008-03-28 2015-12-23 Pacific Biosciences of California, Inc. Methods for nucleic acid sequencing
KR20230083269A (ko) * 2020-07-30 2023-06-09 캠브리지 에피제네틱스 리미티드 핵산 분석을 위한 조성물 및 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8910880D0 (en) * 1989-05-11 1989-06-28 Amersham Int Plc Sequencing method
WO1995006138A1 (en) * 1993-08-25 1995-03-02 The Regents Of The University Of California Microscopic method for detecting micromotions
US5747247A (en) * 1994-07-25 1998-05-05 The Regents Of The University Of California Spectroscopic helicase assay
US5958696A (en) * 1997-07-17 1999-09-28 Boehringer Ingelheim Pharmaceuticals, Inc. Quantitative solid phase helicase assay
ATE225858T1 (de) * 1997-07-28 2002-10-15 Medical Biosystems Ltd Sequenzanalyse von nukleinsäuren
GB9923644D0 (en) * 1999-10-06 1999-12-08 Medical Biosystems Ltd DNA sequencing

Also Published As

Publication number Publication date
MXPA01009997A (es) 2002-08-20
AU3978100A (en) 2000-10-23
WO2000060114A3 (en) 2002-01-31
IL145579A0 (en) 2002-06-30
JP2002540800A (ja) 2002-12-03
KR20020008139A (ko) 2002-01-29
IL145579A (en) 2008-03-20
KR100846884B1 (ko) 2008-07-17
NZ514347A (en) 2004-02-27
EP1198590A2 (en) 2002-04-24
GB9907812D0 (en) 1999-06-02
CN1201018C (zh) 2005-05-11
IS6089A (is) 2001-09-26
US20080096206A1 (en) 2008-04-24
CN1345379A (zh) 2002-04-17
CA2367277A1 (en) 2000-10-12
WO2000060114A2 (en) 2000-10-12
AU769140B2 (en) 2004-01-15

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1962 DE 12/08/2008.