BR0008298A - Métodos para promover o fluxo sanguìneo dentro da vasculatura de um mamìfero, para pacificar tecidos colagenosos danificados dentro de um mamìfero, para pacificar a superfìcie de um biomaterial prostático para uso em associação com um mamìfero, e para mediar a reparação de feridas em um mamìfero - Google Patents

Métodos para promover o fluxo sanguìneo dentro da vasculatura de um mamìfero, para pacificar tecidos colagenosos danificados dentro de um mamìfero, para pacificar a superfìcie de um biomaterial prostático para uso em associação com um mamìfero, e para mediar a reparação de feridas em um mamìfero

Info

Publication number
BR0008298A
BR0008298A BR0008298-8A BR0008298A BR0008298A BR 0008298 A BR0008298 A BR 0008298A BR 0008298 A BR0008298 A BR 0008298A BR 0008298 A BR0008298 A BR 0008298A
Authority
BR
Brazil
Prior art keywords
mammal
pacify
vasculature
blood flow
biomaterial
Prior art date
Application number
BR0008298-8A
Other languages
English (en)
Inventor
Paul O Sheppard
Gerald W Lasser
Paul D Bishop
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of BR0008298A publication Critical patent/BR0008298A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

"MéTODOS PARA PROMOVER O FLUXO SANGUìNEO DENTRO DA VASCULATURA DE UM MAMìFERO, PARA PACIFICAR TECIDOS COLAGENOSOS DANIFICADOS DENTRO DE UM MAMìFERO, PARA PACIFICAR A SUPERFìCIE DE UM BIOMATERIAL PROSTáTICO PARA USO EM ASSOCIAçãO COM UM MAMìFERO, E, PARA MEDIAR A REPARAçãO DE FERIDAS EM UM MAMìFERO". A presente invenção diz respeito a moléculas de polinucleotídeos e de polipeptídeos para uso como inibidores na hemostase e na função imune. Tais inibidores são membros da família de proteínas que carregam um domínio semelhante a colágeno e um domínio globular. Os inibidores são úteis para prover o fluxo sanguíneo na vasculatura, mediante redução da atividade trombogênica e do complemento. Os inibidores também são úteis para pacificar as superfícies colagenosas e modular a cura de feridas.
BR0008298-8A 1999-02-19 2000-02-17 Métodos para promover o fluxo sanguìneo dentro da vasculatura de um mamìfero, para pacificar tecidos colagenosos danificados dentro de um mamìfero, para pacificar a superfìcie de um biomaterial prostático para uso em associação com um mamìfero, e para mediar a reparação de feridas em um mamìfero BR0008298A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US25360499A 1999-02-19 1999-02-19
US44479499A 1999-11-22 1999-11-22
PCT/US2000/004161 WO2000048625A2 (en) 1999-02-19 2000-02-17 Inhibitors for use in hemostasis and immune function

Publications (1)

Publication Number Publication Date
BR0008298A true BR0008298A (pt) 2002-02-19

Family

ID=26943406

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0008298-8A BR0008298A (pt) 1999-02-19 2000-02-17 Métodos para promover o fluxo sanguìneo dentro da vasculatura de um mamìfero, para pacificar tecidos colagenosos danificados dentro de um mamìfero, para pacificar a superfìcie de um biomaterial prostático para uso em associação com um mamìfero, e para mediar a reparação de feridas em um mamìfero

Country Status (20)

Country Link
US (1) US6448221B1 (pt)
EP (2) EP1154785B1 (pt)
JP (1) JP2002537270A (pt)
KR (1) KR20010102130A (pt)
CN (1) CN1341027A (pt)
AT (1) ATE245439T1 (pt)
AU (1) AU772103B2 (pt)
BR (1) BR0008298A (pt)
CA (1) CA2361273A1 (pt)
CZ (1) CZ20012916A3 (pt)
DE (1) DE60004015T2 (pt)
DK (1) DK1154785T3 (pt)
ES (1) ES2202061T3 (pt)
HK (1) HK1039892A1 (pt)
HU (1) HUP0105284A3 (pt)
IL (1) IL144460A0 (pt)
NO (1) NO20014012L (pt)
PL (1) PL349924A1 (pt)
PT (1) PT1154785E (pt)
WO (1) WO2000048625A2 (pt)

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Publication number Priority date Publication date Assignee Title
US6525174B1 (en) 1997-06-06 2003-02-25 Human Genome Sciences, Inc. Precerebellin-like protein
US20040014650A1 (en) * 2002-07-17 2004-01-22 Sheppard Paul D Methods for enhancing wound repair
US6544946B1 (en) * 1999-02-19 2003-04-08 Zymogenetics, Inc. Inhibitors for use in hemostasis and immune function
US8236048B2 (en) 2000-05-12 2012-08-07 Cordis Corporation Drug/drug delivery systems for the prevention and treatment of vascular disease
MY128992A (en) * 2000-08-25 2007-03-30 Merck Patent Gmbh Saratin for inhibiting platelet adhesion to collagen
DE60124285T3 (de) 2000-09-29 2011-03-17 Cordis Corp., Miami Lakes Beschichtete medizinische geräte
CA2478675A1 (en) * 2002-03-08 2003-09-18 Zymogenetics, Inc. Inhibitors for use in hemostasis
NO20035748D0 (no) * 2003-12-19 2003-12-19 Amersham Health As Optisk avbildning av sårbar arteriosklerose
US9471978B2 (en) 2004-10-04 2016-10-18 Banner Health Methodologies linking patterns from multi-modality datasets
WO2006104964A2 (en) * 2005-03-28 2006-10-05 University Of Louisville Research Foundation, Inc. Inhibition of wet type age related macular degeneration (amd) by adiponectin or acrp 30
WO2007014798A2 (en) * 2005-07-29 2007-02-08 Laboratoires Serono S.A. Use of the globular domain of acrp30 for the preparation of a medicament for the prevention and/or treatment of thrombosis-related diseases
WO2008075589A1 (ja) * 2006-12-21 2008-06-26 Chisso Corporation 血小板凝集惹起物質
JP5747370B2 (ja) * 2009-03-31 2015-07-15 国立大学法人浜松医科大学 高病原性口腔細菌の高感度検出法
WO2023215294A1 (en) * 2022-05-02 2023-11-09 The Board Of Trustees Of The Leland Stanford Junior University Complement pathway inhibition for wound healing

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5869330A (en) 1995-06-05 1999-02-09 Whitehead Institute For Biomedical Research DNA encoding a novel serum protein produced exclusively in adipocytes
EP1000084A4 (en) 1997-07-08 2003-03-26 Human Genome Sciences Inc 123 PROTEIN SEPARATED BY HUMAN
US6265544B1 (en) * 1997-07-18 2001-07-24 Zymogenetics, Inc. Adipocyte-specific protein homologs
PT1000149E (pt) 1997-08-01 2007-08-03 Serono Genetics Inst Sa 5' ests para proteínas segregadas identificadas a partir de tecidos do cérebro.
DE69834334T2 (de) 1997-08-26 2007-04-26 Zymogenetics, Inc., Seattle Für adipozyten spezifische protein homologe
DK1033134T3 (da) 1997-10-29 2007-07-16 Otsuka Pharma Co Ltd Sammensætninger, som inhiberer proliferation af glat muskel, og fremgangsmåde til diagnosticering af arteriosklerose
EP1037979A2 (en) 1997-12-03 2000-09-27 Genentech, Inc. Polypeptides and nucleic acids encoding the same
AU1929599A (en) 1997-12-30 1999-07-19 Chiron Corporation Bone marrow secreted proteins and polynucleotides
ID27813A (id) 1998-01-28 2001-04-26 Corixa Corp Senyawa-senyawa untuk terapi dan diagnosa kanker paru-paru dan metoda untuk penggunaannya
CA2327317A1 (en) 1998-04-29 1999-11-04 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
EP1085897A4 (en) 1998-05-21 2003-03-12 Smithkline Beecham Corp ACRP30R1L, ACRP30 APPROVED (PROTEIN ASSOCIATED WITH A 30 KD ADIPOCYTE COMPLEMENT)

Also Published As

Publication number Publication date
CZ20012916A3 (cs) 2002-05-15
WO2000048625A3 (en) 2000-12-28
ES2202061T3 (es) 2004-04-01
EP1154785A2 (en) 2001-11-21
EP1154785B1 (en) 2003-07-23
AU772103B2 (en) 2004-04-08
DE60004015D1 (de) 2003-08-28
PL349924A1 (en) 2002-10-21
HUP0105284A3 (en) 2003-12-29
US6448221B1 (en) 2002-09-10
KR20010102130A (ko) 2001-11-15
AU2883200A (en) 2000-09-04
EP1382345A2 (en) 2004-01-21
ATE245439T1 (de) 2003-08-15
JP2002537270A (ja) 2002-11-05
DE60004015T2 (de) 2004-04-15
CN1341027A (zh) 2002-03-20
IL144460A0 (en) 2002-05-23
HK1039892A1 (zh) 2002-05-17
HUP0105284A2 (hu) 2002-05-29
NO20014012D0 (no) 2001-08-17
CA2361273A1 (en) 2000-08-24
WO2000048625A2 (en) 2000-08-24
NO20014012L (no) 2001-10-02
DK1154785T3 (da) 2003-11-17
EP1382345A3 (en) 2004-01-28
PT1154785E (pt) 2003-12-31

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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