BR0007782B1 - processo para purificar Ácido hialurânico de alto peso molecular. - Google Patents

processo para purificar Ácido hialurânico de alto peso molecular.

Info

Publication number
BR0007782B1
BR0007782B1 BRPI0007782-8B1A BR0007782A BR0007782B1 BR 0007782 B1 BR0007782 B1 BR 0007782B1 BR 0007782 A BR0007782 A BR 0007782A BR 0007782 B1 BR0007782 B1 BR 0007782B1
Authority
BR
Brazil
Prior art keywords
molecular weight
high molecular
purifying high
aqueous solution
hyaluronic acid
Prior art date
Application number
BRPI0007782-8B1A
Other languages
English (en)
Other versions
BR0007782A (pt
Inventor
Stefano Carlino
Francois Magnette
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BR0007782A publication Critical patent/BR0007782A/pt
Publication of BR0007782B1 publication Critical patent/BR0007782B1/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

Landscapes

  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polyethers (AREA)
BRPI0007782-8B1A 1999-01-28 2000-01-27 processo para purificar Ácido hialurânico de alto peso molecular. BR0007782B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH00154/99A CH692919A5 (fr) 1999-01-28 1999-01-28 Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
PCT/IB2000/000082 WO2000044925A1 (en) 1999-01-28 2000-01-27 Process for purifying high molecular weight hyaluronic acid

Publications (2)

Publication Number Publication Date
BR0007782A BR0007782A (pt) 2002-09-10
BR0007782B1 true BR0007782B1 (pt) 2013-08-27

Family

ID=4180486

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0007782-8B1A BR0007782B1 (pt) 1999-01-28 2000-01-27 processo para purificar Ácido hialurânico de alto peso molecular.

Country Status (13)

Country Link
US (1) US6489467B1 (pt)
EP (1) EP1144668B1 (pt)
AT (1) ATE242816T1 (pt)
AU (1) AU3070400A (pt)
BR (1) BR0007782B1 (pt)
CA (1) CA2360343C (pt)
CH (1) CH692919A5 (pt)
CZ (1) CZ301306B6 (pt)
DE (1) DE60003282T2 (pt)
ES (1) ES2200812T3 (pt)
PL (1) PL200677B1 (pt)
SK (1) SK286327B6 (pt)
WO (1) WO2000044925A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH692919A5 (fr) * 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.
ES2192960B1 (es) * 2001-11-16 2005-03-01 Consejo Sup. Investig. Cientificas Nuevo procedimiento de obtencion de acido hialuronico.
WO2004014399A1 (en) * 2002-08-07 2004-02-19 Laboratoire Medidom S.A. Process for preparing a sterile high molecular weight hyaluronic acid formulation
US7002007B2 (en) * 2004-05-28 2006-02-21 Calcigen Corporation Production of high molecular weight hyaluronates
KR100577075B1 (ko) * 2004-06-16 2006-05-08 주식회사 티앤라이프시스템 칼슘염 및 인산염, 또는 인산칼슘염을 이용한 히아루론산정제방법
GB0502096D0 (en) * 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
WO2008035372A2 (en) 2006-07-06 2008-03-27 Reliance Life Sciences Pvt Ltd Efficient process for purification of high molecular weight hyaluronic acid
CN100478360C (zh) * 2006-10-31 2009-04-15 山东福瑞达生物化工有限公司 将浓缩用于透明质酸或其盐的生产的方法
ES2622834T3 (es) * 2007-11-13 2017-07-07 Bio-Technology General (Israel) Ltd. Procedimiento de esterilización por filtración en estado diluido para biopolímeros viscoelásticos
DE102009021372A1 (de) * 2009-05-14 2010-11-18 Ursapharm Arzneimittel Gmbh Phosphatfreie pharmazeutische Zusammensetzung zur Glaukombehandlung
US8283463B2 (en) 2010-02-09 2012-10-09 Bausch & Lomb Incorporated Sterile hyaluronic acid solutions
WO2011114475A1 (ja) * 2010-03-17 2011-09-22 電気化学工業株式会社 ヒアルロン酸及び/又はその塩の精製方法
CN102504047A (zh) * 2011-11-30 2012-06-20 上海景峰制药有限公司 一种玻璃酸钠发酵液的超滤方法
US9315588B2 (en) 2012-02-03 2016-04-19 University Of Rochester Compositions and methods for recombinant synthesis of high molecular weight hyaluronic acid
CN105237656A (zh) * 2015-10-30 2016-01-13 深圳市阳光之路生物材料科技有限公司 一种提纯透明质酸钠的方法
GB201703850D0 (en) * 2017-03-10 2017-04-26 Givaudan Sa Improvements in or relating to organic compounds
IT201900019724A1 (it) 2019-10-24 2021-04-24 Bmg Pharma S P A “procedimento in solvente organico per la purificazione dell’acido ialuronico sale sodico”

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4517295A (en) * 1983-02-18 1985-05-14 Diagnostic, Inc. Hyaluronic acid from bacterial culture
JPH072117B2 (ja) 1986-10-09 1995-01-18 三菱レイヨン株式会社 ヒアルロン酸の製造法
IT1271001B (it) * 1994-07-26 1997-05-26 Poli Ind Chimica Spa Procedimento di preparazione di acido ialuronico mediante fermentazione con streptococcus
CH692919A5 (fr) * 1999-01-28 2002-12-13 Trb Chemedica S A Procédé de purification de l'acide hyaluronique à poids moléculaire élevé.

Also Published As

Publication number Publication date
PL200677B1 (pl) 2009-01-30
CH692919A5 (fr) 2002-12-13
EP1144668A1 (en) 2001-10-17
SK10632001A3 (sk) 2002-04-04
EP1144668B1 (en) 2003-06-11
DE60003282T2 (de) 2004-05-06
WO2000044925A1 (en) 2000-08-03
BR0007782A (pt) 2002-09-10
AU3070400A (en) 2000-08-18
CZ20012694A3 (cs) 2002-02-13
CA2360343C (en) 2010-02-23
US6489467B1 (en) 2002-12-03
PL350135A1 (en) 2002-11-04
CA2360343A1 (en) 2000-08-03
DE60003282D1 (de) 2003-07-17
CZ301306B6 (cs) 2010-01-06
ATE242816T1 (de) 2003-06-15
ES2200812T3 (es) 2004-03-16
SK286327B6 (en) 2008-07-07

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 27/08/2013, OBSERVADAS AS CONDICOES LEGAIS.