BG49708A3 - Method for preparing injector solution contain electric indifferent policyclic ironcomplex - Google Patents
Method for preparing injector solution contain electric indifferent policyclic ironcomplexInfo
- Publication number
- BG49708A3 BG49708A3 BG062649A BG6264983A BG49708A3 BG 49708 A3 BG49708 A3 BG 49708A3 BG 062649 A BG062649 A BG 062649A BG 6264983 A BG6264983 A BG 6264983A BG 49708 A3 BG49708 A3 BG 49708A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- ironcomplex
- policyclic
- indifferent
- preparing
- equivalents
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 150000004698 iron complex Chemical class 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 6
- NAOLWIGVYRIGTP-UHFFFAOYSA-N 1,3,5-trihydroxyanthracene-9,10-dione Chemical compound C1=CC(O)=C2C(=O)C3=CC(O)=CC(O)=C3C(=O)C2=C1 NAOLWIGVYRIGTP-UHFFFAOYSA-N 0.000 abstract 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 229920002307 Dextran Polymers 0.000 abstract 1
- 238000004821 distillation Methods 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960004887 ferric hydroxide Drugs 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical compound [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 abstract 1
- PVFSDGKDKFSOTB-UHFFFAOYSA-K iron(3+);triacetate Chemical compound [Fe+3].CC([O-])=O.CC([O-])=O.CC([O-])=O PVFSDGKDKFSOTB-UHFFFAOYSA-K 0.000 abstract 1
- 239000002244 precipitate Substances 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/02—Iron compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Методът намира приложение в медицината. Полученият по него инжекционен разтвор освобождава желязото ин виво на няколко етапа с възможност за регулиране, а самият метод е опростен. Съгласно метода прясно утаена и промита до отстраняване на анионите утайка, състояща се от ферихидроокис, се разтваря в оцетна киселина. Така полученият фериацетат взаимодейства с 0,25 0,5 еквивалента захарна киселина и 0,25 0,5 еквивалента декстран или с 0,4 1 еквивалента захарна киселина, след това оцетната киселина се дестилира с водна пара, като дестилацията продължава, докато рн достигне стойност 4,5 5,0.2 претенции, 1 фигураThe method is used in medicine. The injection solution obtained by it releases the iron in vivo in several adjustable stages, and the method itself is simplified. According to the method, a freshly precipitated and anion-washed precipitate consisting of ferric hydroxide is dissolved in acetic acid. The ferricacetate thus obtained is reacted with 0.25 0.5 equivalents of saccharic acid and 0.25 0.5 equivalents of dextran or with 0.4 1 equivalents of saccharic acid, then the acetic acid is steam distilled, the distillation continuing until the pH reaches value 4.5 5.0.2 claims, 1 figure
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU328182A HU187167B (en) | 1982-10-15 | 1982-10-15 | Process for producing pharmaceutical solution of new type polynuclear iron/iii/ mixed complex activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG49708A3 true BG49708A3 (en) | 1992-01-15 |
Family
ID=10963435
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG062649A BG49708A3 (en) | 1982-10-15 | 1983-10-14 | Method for preparing injector solution contain electric indifferent policyclic ironcomplex |
Country Status (11)
| Country | Link |
|---|---|
| AT (1) | AT385655B (en) |
| BE (1) | BE897980A (en) |
| BG (1) | BG49708A3 (en) |
| DE (1) | DE3337506A1 (en) |
| DK (1) | DK476583A (en) |
| ES (1) | ES8406196A1 (en) |
| FI (1) | FI80830C (en) |
| FR (1) | FR2534589B1 (en) |
| GB (1) | GB2129821B (en) |
| HU (1) | HU187167B (en) |
| SE (1) | SE462140B (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3728814A1 (en) * | 1987-08-28 | 1989-03-30 | Lentia Gmbh | SOLUTION FOR USE AS A RINSING LIQUID IN THE DESTRUCTION OF NON-BODY DEPOSITS IN HUMAN AND ANIMAL TISSUES OR BODIES |
| DE4445772A1 (en) * | 1993-12-27 | 1995-06-29 | Loeser Thomas Dr Ing | Determn. of required dosage of trace elements and minerals in medicaments |
| DE19712493A1 (en) * | 1997-03-25 | 1998-10-01 | Univ Karlsruhe | Pharmaceutical composition comprises iron calcium poly:ate |
| DE10249552A1 (en) | 2002-10-23 | 2004-05-13 | Vifor (International) Ag | Water-soluble iron-carbohydrate complexes, their preparation and medicaments containing them |
| US20040170724A1 (en) | 2003-02-28 | 2004-09-02 | Kraft Foods Holdings, Inc. | Mineral complexes of lactobionic acid and method of using for mineral fortification of food products |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE862482C (en) * | 1950-05-14 | 1953-01-12 | Merck Chem Fab E | Process for the preparation of durable, injectable solutions of salts of trivalent iron |
| DE938502C (en) * | 1953-02-27 | 1956-02-02 | Benger S Ltd | Method of making a colloidal iron preparation |
| GB978485A (en) * | 1960-10-26 | 1964-12-23 | Astra Apotekarnes Kem Fab | Iron preparations for intramuscular injection |
| DE1293144B (en) * | 1964-11-04 | 1969-04-24 | Hausmann Ag Labor | Process for the production of complex compounds of iron with sorbitol, gluconic acid and an oligosaccharide |
| DK122890B (en) * | 1964-12-29 | 1972-04-24 | J Reumert | Process for the preparation of ferric hydroxide dextran complexes. |
| DE1617463A1 (en) * | 1965-11-20 | 1971-04-08 | Bayer Ag | Process for the manufacture of injectable colloidal iron preparations |
| GB1149137A (en) * | 1966-10-28 | 1969-04-16 | H C F Porsche K G Ing | Screw outboard drive for boats |
| AT279048B (en) * | 1967-07-04 | 1970-02-25 | Pharmazeutische Fabrik Montavit Gmbh | Process for the preparation of new, soluble and stable organic iron (III) complex compounds and injection solutions thereof |
| DE2527158A1 (en) * | 1975-06-18 | 1976-12-23 | Herz Eberhard | MEDICINAL PRODUCTS FOR THE TREATMENT OF INFECTIOUS DISEASES AND INFLAMMATION IN HUMAN AND VETERINAL MEDICINE THAT CANNOT BE DETECTED BY MICROORGANISMS |
| JPS6039681B2 (en) * | 1976-01-01 | 1985-09-07 | 日本臓器製薬株式会社 | Dextrin-citric acid-ferric polynuclear complex and parenteral iron preparation containing the complex |
| GB2006243B (en) * | 1977-09-29 | 1982-07-14 | Atomic Energy Authority Uk | Compounds |
| DE3026868C2 (en) * | 1980-07-16 | 1986-03-13 | Laboratorien Hausmann AG, St. Gallen | Process for the preparation of iron (III) hydroxide-dextran complexes and pharmaceutical sterile aqueous solution containing them |
-
1982
- 1982-10-15 HU HU328182A patent/HU187167B/en not_active IP Right Cessation
-
1983
- 1983-10-12 AT AT363983A patent/AT385655B/en not_active IP Right Cessation
- 1983-10-12 FI FI833707A patent/FI80830C/en not_active IP Right Cessation
- 1983-10-13 BE BE0/211691A patent/BE897980A/en not_active IP Right Cessation
- 1983-10-14 DK DK476583A patent/DK476583A/en not_active Application Discontinuation
- 1983-10-14 SE SE8305665A patent/SE462140B/en not_active IP Right Cessation
- 1983-10-14 ES ES526481A patent/ES8406196A1/en not_active Expired
- 1983-10-14 BG BG062649A patent/BG49708A3/en unknown
- 1983-10-14 DE DE19833337506 patent/DE3337506A1/en active Granted
- 1983-10-14 GB GB08327633A patent/GB2129821B/en not_active Expired
- 1983-10-14 FR FR8316377A patent/FR2534589B1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES526481A0 (en) | 1984-08-01 |
| FI833707A0 (en) | 1983-10-12 |
| DK476583D0 (en) | 1983-10-14 |
| ATA363983A (en) | 1987-10-15 |
| FR2534589A1 (en) | 1984-04-20 |
| DE3337506C2 (en) | 1991-07-04 |
| FI80830C (en) | 1990-08-10 |
| SE462140B (en) | 1990-05-14 |
| GB8327633D0 (en) | 1983-11-16 |
| BE897980A (en) | 1984-01-30 |
| GB2129821B (en) | 1986-02-19 |
| DK476583A (en) | 1984-04-16 |
| FI833707A (en) | 1984-04-16 |
| FR2534589B1 (en) | 1988-12-16 |
| SE8305665D0 (en) | 1983-10-14 |
| GB2129821A (en) | 1984-05-23 |
| ES8406196A1 (en) | 1984-08-01 |
| HU187167B (en) | 1985-11-28 |
| AT385655B (en) | 1988-05-10 |
| FI80830B (en) | 1990-04-30 |
| DE3337506A1 (en) | 1984-04-19 |
| SE8305665L (en) | 1984-04-16 |
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