BG33436A3 - Metod za poluchavane na 4- dezacetil- vinblastin- 3- spiro- 5"- oksazolidin- 2", 4"- dion - Google Patents

Metod za poluchavane na 4- dezacetil- vinblastin- 3- spiro- 5"- oksazolidin- 2", 4"- dion

Info

Publication number
BG33436A3
BG33436A3 BG7737936A BG3793677A BG33436A3 BG 33436 A3 BG33436 A3 BG 33436A3 BG 7737936 A BG7737936 A BG 7737936A BG 3793677 A BG3793677 A BG 3793677A BG 33436 A3 BG33436 A3 BG 33436A3
Authority
BG
Bulgaria
Prior art keywords
dezacetyl
dion
oxazolidin
vinblastine
spiro
Prior art date
Application number
BG7737936A
Other languages
English (en)
Inventor
Miller
Getowski
Original Assignee
Eli Lilly And Co,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly And Co,Us filed Critical Eli Lilly And Co,Us
Publication of BG33436A3 publication Critical patent/BG33436A3/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
BG7737936A 1976-12-06 1977-12-02 Metod za poluchavane na 4- dezacetil- vinblastin- 3- spiro- 5"- oksazolidin- 2", 4"- dion BG33436A3 (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/747,575 US4096148A (en) 1976-12-06 1976-12-06 Oxazolidinedione derivatives of Vinca alkaloids

Publications (1)

Publication Number Publication Date
BG33436A3 true BG33436A3 (bg) 1983-02-15

Family

ID=25005690

Family Applications (1)

Application Number Title Priority Date Filing Date
BG7737936A BG33436A3 (bg) 1976-12-06 1977-12-02 Metod za poluchavane na 4- dezacetil- vinblastin- 3- spiro- 5"- oksazolidin- 2", 4"- dion

Country Status (31)

Country Link
US (1) US4096148A (bg)
JP (1) JPS5371100A (bg)
AR (1) AR218467A1 (bg)
AT (2) AT353987B (bg)
AU (1) AU513936B2 (bg)
BE (1) BE861417A (bg)
BG (1) BG33436A3 (bg)
CA (2) CA1082180A (bg)
CH (2) CH632516A5 (bg)
CS (2) CS195343B2 (bg)
DD (2) DD134228A5 (bg)
DE (1) DE2753791A1 (bg)
DK (2) DK144916C (bg)
ES (2) ES464765A1 (bg)
FR (1) FR2372839A1 (bg)
GB (1) GB1590649A (bg)
GR (2) GR67243B (bg)
HK (1) HK57281A (bg)
HU (2) HU180725B (bg)
IE (1) IE46105B1 (bg)
IL (1) IL53506A (bg)
MX (1) MX4326E (bg)
MY (1) MY8200176A (bg)
NL (1) NL7713336A (bg)
NZ (1) NZ185818A (bg)
PL (2) PL110671B1 (bg)
PT (2) PT67342B (bg)
RO (2) RO74137A (bg)
SE (2) SE436036B (bg)
SU (2) SU865127A3 (bg)
ZA (1) ZA777237B (bg)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181874B (en) * 1977-08-08 1983-11-28 Lilly Co Eli Process for preparing amides of deacetyl-leurosine and deacetyl-leuroformine
US4357334A (en) * 1980-03-20 1982-11-02 Eli Lilly And Company Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms
US4362664A (en) * 1980-12-29 1982-12-07 Eli Lilly And Company Vinblastine oxazolidinedione disulfides and related compounds
EP0124502B1 (fr) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Nouveaux conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques contenant ces conjugués
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények
EP2266607A3 (en) 1999-10-01 2011-04-20 Immunogen, Inc. Immunoconjugates for treating cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT649883A (bg) * 1960-05-24
HU165986B (bg) * 1973-02-16 1974-12-28
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US4012390A (en) * 1974-10-16 1977-03-15 Eli Lilly And Company Vinblastinoic acid

Also Published As

Publication number Publication date
PL106522B1 (pl) 1979-12-31
MX4326E (es) 1982-03-24
SE7713586L (sv) 1978-06-07
CA1082180A (en) 1980-07-22
IL53506A0 (en) 1978-03-10
DE2753791C2 (bg) 1990-08-02
NL7713336A (nl) 1978-06-08
AU513936B2 (en) 1981-01-15
NZ185818A (en) 1979-12-11
JPS625160B2 (bg) 1987-02-03
ATA868877A (de) 1979-05-15
DD134227A5 (de) 1979-02-14
AR218467A1 (es) 1980-06-13
GR67243B (bg) 1981-06-25
PT67342B (en) 1979-04-26
ES464764A1 (es) 1979-01-01
HU180724B (en) 1983-04-29
IL53506A (en) 1981-09-13
SE7713587L (sv) 1978-06-07
PL110671B1 (en) 1980-07-31
RO74137A (ro) 1981-08-30
US4096148A (en) 1978-06-20
HK57281A (en) 1981-11-27
DK144916B (da) 1982-07-05
PT67343B (en) 1979-04-26
ZA777237B (en) 1979-07-25
HU180725B (en) 1983-04-29
PL202660A1 (pl) 1978-08-28
SE436036B (sv) 1984-11-05
SU865127A3 (ru) 1981-09-15
SE435930B (sv) 1984-10-29
DK144916C (da) 1982-12-06
PL202659A1 (pl) 1978-12-04
FR2372839B1 (bg) 1981-11-06
AT353987B (de) 1979-12-10
PT67343A (en) 1977-12-01
SU843753A3 (ru) 1981-06-30
DD134228A5 (de) 1979-02-14
CS195343B2 (en) 1980-01-31
DE2753791A1 (de) 1978-06-08
CH632516A5 (de) 1982-10-15
CS195344B2 (en) 1980-01-31
JPS5371100A (en) 1978-06-24
DK541077A (da) 1978-06-07
AT361638B (de) 1981-03-25
IE46105L (en) 1978-06-06
PT67342A (en) 1977-12-01
DK145001C (da) 1982-12-27
ES464765A1 (es) 1979-01-01
ATA868777A (de) 1980-08-15
CH634076A5 (de) 1983-01-14
DK145001B (da) 1982-07-26
IE46105B1 (en) 1983-02-23
FR2372839A1 (fr) 1978-06-30
CA1103664A (en) 1981-06-23
MY8200176A (en) 1982-12-31
RO75391A (ro) 1980-11-30
DK541177A (da) 1978-06-07
GB1590649A (en) 1981-06-03
GR67244B (bg) 1981-06-25
BE861417A (fr) 1978-06-02
AU3123077A (en) 1979-06-14

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