BG106937A - Novel indole derivatives - Google Patents

Novel indole derivatives

Info

Publication number
BG106937A
BG106937A BG106937A BG10693702A BG106937A BG 106937 A BG106937 A BG 106937A BG 106937 A BG106937 A BG 106937A BG 10693702 A BG10693702 A BG 10693702A BG 106937 A BG106937 A BG 106937A
Authority
BG
Bulgaria
Prior art keywords
indole derivatives
novel indole
novel
compounds
5ht1a
Prior art date
Application number
BG106937A
Other languages
Bulgarian (bg)
English (en)
Inventor
Thomas Ruhland
- JENSEN Christian KROG
Mario Rottlaender
Gitte Mikkelsen
Kim Andersen
Ejner Moltzen
Original Assignee
H.Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H.Lundbeck A/S filed Critical H.Lundbeck A/S
Publication of BG106937A publication Critical patent/BG106937A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG106937A 1999-12-30 2002-07-22 Novel indole derivatives BG106937A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199901889 1999-12-30
PCT/DK2000/000742 WO2001049680A1 (en) 1999-12-30 2000-12-29 Novel indole derivatives

Publications (1)

Publication Number Publication Date
BG106937A true BG106937A (en) 2003-04-30

Family

ID=8108836

Family Applications (1)

Application Number Title Priority Date Filing Date
BG106937A BG106937A (en) 1999-12-30 2002-07-22 Novel indole derivatives

Country Status (23)

Country Link
US (1) US20030050307A1 (no)
EP (1) EP1246818A1 (no)
JP (1) JP2003519226A (no)
KR (1) KR20020063288A (no)
CN (1) CN1437598A (no)
AR (1) AR027134A1 (no)
AU (1) AU2352101A (no)
BG (1) BG106937A (no)
BR (1) BR0016955A (no)
CA (1) CA2395606A1 (no)
CZ (1) CZ20022489A3 (no)
EA (1) EA200200727A1 (no)
HU (1) HUP0203767A3 (no)
IL (1) IL150336A0 (no)
IS (1) IS6434A (no)
MX (1) MXPA02006498A (no)
NO (1) NO20023148D0 (no)
NZ (1) NZ519648A (no)
PL (1) PL355538A1 (no)
SK (1) SK9452002A3 (no)
TR (1) TR200201689T2 (no)
WO (1) WO2001049680A1 (no)
ZA (1) ZA200204969B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002243394A1 (en) 2000-11-16 2002-06-24 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
US6656950B2 (en) 2001-04-25 2003-12-02 Wyeth Antidepressant azaheterocyclylmethyl derivatives of 1,4-dioxino[2,3-b]pyridine
ES2247347T3 (es) * 2001-06-29 2006-03-01 H. Lundbeck A/S Nuevos derivados de indol.
JP4745661B2 (ja) 2002-08-22 2011-08-10 大日本住友製薬株式会社 統合失調症治療剤
AU2004249621B2 (en) * 2003-06-23 2009-08-06 Dainippon Sumitomo Pharma Co., Ltd. Therapeutic agent for senile dementia
WO2005080976A1 (ja) 2004-02-20 2005-09-01 Dainippon Sumitomo Pharma Co., Ltd. 統合失調症の記憶・学習機能障害治療薬のin vivoスクリーニング方法
TWI329641B (en) * 2005-08-31 2010-09-01 Otsuka Pharma Co Ltd (benzo[b]thiophen-4-yl)piperazine compounds, pharmaceutical compositions comprising the same, uses of the same and processes for preparing the same
JP4785881B2 (ja) * 2007-02-27 2011-10-05 大塚製薬株式会社 医薬
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
PL395469A1 (pl) * 2011-06-29 2013-01-07 Adamed Spólka Z Ograniczona Odpowiedzialnoscia Pochodne indoloamin do leczenia chorób osrodkowego ukladu nerwowego
CN116554145A (zh) * 2022-01-29 2023-08-08 江苏恩华药业股份有限公司 芳烷基-4-(1h)吲哚基哌嗪衍生物、其制备方法和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2567884B1 (fr) * 1984-07-19 1987-03-06 Roussel Uclaf Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DK148392D0 (da) * 1992-12-09 1992-12-09 Lundbeck & Co As H Heterocykliske forbindelser
EP0900792B1 (en) * 1997-09-02 2003-10-29 Duphar International Research B.V Piperazine and piperidine derivatives as 5-HT1A and dopamine D2-receptor (ant)agonists
EP1076647A2 (en) * 1998-04-29 2001-02-21 American Home Products Corporation Antipsychotic indolyl derivatives

Also Published As

Publication number Publication date
SK9452002A3 (en) 2002-11-06
US20030050307A1 (en) 2003-03-13
IL150336A0 (en) 2002-12-01
TR200201689T2 (tr) 2002-10-21
MXPA02006498A (es) 2002-11-29
HUP0203767A3 (en) 2004-06-28
CN1437598A (zh) 2003-08-20
AU2352101A (en) 2001-07-16
NZ519648A (en) 2004-05-28
HUP0203767A2 (hu) 2003-03-28
NO20023148L (no) 2002-06-28
EP1246818A1 (en) 2002-10-09
IS6434A (is) 2002-06-19
KR20020063288A (ko) 2002-08-01
WO2001049680A1 (en) 2001-07-12
CA2395606A1 (en) 2001-07-12
NO20023148D0 (no) 2002-06-28
JP2003519226A (ja) 2003-06-17
AR027134A1 (es) 2003-03-12
CZ20022489A3 (cs) 2002-10-16
EA200200727A1 (ru) 2002-12-26
ZA200204969B (en) 2003-09-22
BR0016955A (pt) 2003-04-29
PL355538A1 (en) 2004-05-04

Similar Documents

Publication Publication Date Title
NZ335091A (en) Use of condensated (hetaryl-substituted) 1-benzal-3-pyrazol derivatives as vasodilators
PL338452A1 (en) Novel substituted 6-phenylphenatridines
NL350075I2 (no)
MXPA05010652A (es) Pirazoles sustituidos.
BG106933A (en) Dihydro-1,3,5-triazine amine derivatives and their therapeutic uses
MXPA03008754A (es) Derivados de piridina fundidos para utilizarse como agonistas receptores vaniloide para tratar dolor.
DE59702414D1 (de) Dipeptidische benzamidine als kininogenasen-inhibitoren
ATE186909T1 (de) Cyclische fungizide amide
MY116845A (en) New 19-nor-pregnene derivatives
BG102625A (en) Lactone derivatives of 17-beta-carboxy, carbothio and amide androstane derivatives
BG105028A (en) Bridged indenopyrrolocarbazoles
SE9702773D0 (sv) Novel compounds
PL338339A1 (en) Novel derivatives of tetrazole
BG106937A (en) Novel indole derivatives
IT1315267B1 (it) Derivati di 2-(1h-indol-3-il)-2-oxo-acetammidi ad attivita'antitumorale
TW342385B (en) Bicyclic benzazepin, the process for their preparation and the pharmaceutical composition containing them
BG106961A (en) Phenylpiperazinyl derivatives
DE69924292D1 (de) Pyrazol verbindungen und ihre verwendung
YU1302A (sh) Derivati aminotiazola i njihova primena kao liganada crf receptora
MXPA05010651A (es) Compuestos de pirazol.
BG105710A (en) 5ht1 antagonists for antidepressant therapy
SI1377574T1 (no)
MXPA03003971A (es) Derivados de indol como inhibidores de pde5.
MX9700813A (es) Nuevos derivados 3-substituidos de 3h-2,3-benzodiazepina, su preparacion y su uso como medicamentos.
MXPA02007973A (es) Compuestos de aminoacidos y su uso como inhibidores de nep, ace y ece.