BG105268A - Compounds, compositions and methods for stimulating neuronal growth and elongation - Google Patents
Compounds, compositions and methods for stimulating neuronal growth and elongationInfo
- Publication number
- BG105268A BG105268A BG105268A BG10526801A BG105268A BG 105268 A BG105268 A BG 105268A BG 105268 A BG105268 A BG 105268A BG 10526801 A BG10526801 A BG 10526801A BG 105268 A BG105268 A BG 105268A
- Authority
- BG
- Bulgaria
- Prior art keywords
- compounds
- compositions
- methods
- elongation
- neuronal growth
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9329998P | 1998-07-17 | 1998-07-17 | |
US13288499P | 1999-05-06 | 1999-05-06 | |
PCT/US1999/015965 WO2000004020A1 (en) | 1998-07-17 | 1999-07-15 | Compounds, compositions, and methods for stimulating neuronal growth and elongation |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105268A true BG105268A (en) | 2001-11-30 |
Family
ID=26787372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105268A BG105268A (en) | 1998-07-17 | 2001-02-16 | Compounds, compositions and methods for stimulating neuronal growth and elongation |
Country Status (35)
Country | Link |
---|---|
US (1) | US6630472B1 (zh) |
EP (1) | EP1098897B1 (zh) |
JP (1) | JP2002520413A (zh) |
KR (1) | KR20010071920A (zh) |
CN (1) | CN1318067A (zh) |
AP (1) | AP2001002052A0 (zh) |
AT (1) | ATE268772T1 (zh) |
AU (1) | AU756912B2 (zh) |
BG (1) | BG105268A (zh) |
BR (1) | BR9912423A (zh) |
CA (1) | CA2337377A1 (zh) |
DE (1) | DE69917907T2 (zh) |
DK (1) | DK1098897T3 (zh) |
EA (1) | EA200100149A1 (zh) |
EE (1) | EE200100032A (zh) |
ES (1) | ES2226409T3 (zh) |
GE (1) | GEP20043368B (zh) |
HR (1) | HRP20010118A2 (zh) |
HU (1) | HUP0200637A3 (zh) |
ID (1) | ID27428A (zh) |
IL (1) | IL140676A0 (zh) |
IS (1) | IS5805A (zh) |
LT (1) | LT4850B (zh) |
LV (1) | LV12665B (zh) |
NO (1) | NO20010191L (zh) |
NZ (1) | NZ509211A (zh) |
OA (1) | OA11581A (zh) |
PL (1) | PL345598A1 (zh) |
PT (1) | PT1098897E (zh) |
SI (1) | SI20638A (zh) |
SK (1) | SK462001A3 (zh) |
TR (1) | TR200100122T2 (zh) |
WO (1) | WO2000004020A1 (zh) |
YU (1) | YU2901A (zh) |
ZA (1) | ZA200100320B (zh) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6818643B1 (en) * | 1999-12-08 | 2004-11-16 | Bristol-Myers Squibb Company | Neurotrophic bicyclic diamides |
EP1423119A4 (en) * | 2001-05-10 | 2005-04-13 | Agouron Pharma | HETEROBICYCLES FKBP LIGANDS |
US9914732B2 (en) | 2014-01-24 | 2018-03-13 | Max-Planck-Gesellschaft Zur Forderung Der Wissensc Haften E.V. | Diazabicyclo[4.3.1]decane derivatives for treatment of psychiatric disorders |
EP2899192A1 (en) * | 2014-01-24 | 2015-07-29 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Diazabicyclo[4.3.1]decane derivatives for treatment of psychiatric disorders |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4894366A (en) | 1984-12-03 | 1990-01-16 | Fujisawa Pharmaceutical Company, Ltd. | Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same |
US5196352A (en) | 1989-01-19 | 1993-03-23 | Merck & Co., Inc. | New FK-506 cytosolic binding protein |
US5109112A (en) | 1989-01-19 | 1992-04-28 | Merck & Co., Inc. | FK-506 cytosolic binding protein |
US5192773A (en) | 1990-07-02 | 1993-03-09 | Vertex Pharmaceuticals, Inc. | Immunosuppressive compounds |
US5256656A (en) * | 1990-07-31 | 1993-10-26 | Nisshin Flour Milling Co., Ltd. | Azabicyclo derivatives |
US5187166A (en) * | 1990-07-31 | 1993-02-16 | Nisshin Flour Milling Co., Ltd. | Azabicyclo derivatives and their use as antiemetics |
CA2068062A1 (en) | 1991-05-07 | 1992-11-08 | Stephen A. Parent | Yeast mutants |
US5362629A (en) | 1991-08-05 | 1994-11-08 | President And Fellows Of Harvard College | Detection of immunosuppressants |
US5344831A (en) * | 1992-01-31 | 1994-09-06 | Nisshin Flour Milling Co., Ltd. | Diazabicyclo derivatives |
DE4219973A1 (de) | 1992-06-19 | 1993-12-23 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
US5318895A (en) | 1992-10-05 | 1994-06-07 | Merck & Co., Inc. | Aspergillus niger mutants |
US5798355A (en) | 1995-06-07 | 1998-08-25 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity |
JP3235913B2 (ja) * | 1993-07-30 | 2001-12-04 | エーザイ株式会社 | アミノ安息香酸誘導体 |
US5612350A (en) | 1993-11-30 | 1997-03-18 | Abbott Laboratories | Macrocyclic immunomodulators with novel cyclohexyl ring replacements |
DE4341402A1 (de) | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung |
US5457182A (en) | 1994-02-15 | 1995-10-10 | Merck & Co., Inc. | FK-506 cytosolic binding protein, FKBP12.6 |
US5622866A (en) | 1994-06-23 | 1997-04-22 | Merck & Co., Inc. | Expression cassettes useful in construction of integrative and replicative expression vectors for Streptomyces |
US5859031A (en) * | 1995-06-07 | 1999-01-12 | Gpi Nil Holdings, Inc. | Small molecule inhibitors of rotamase enzyme activity |
US5614547A (en) | 1995-06-07 | 1997-03-25 | Guilford Pharmaceuticals Inc. | Small molecule inhibitors of rotamase enzyme |
US5696135A (en) | 1995-06-07 | 1997-12-09 | Gpi Nil Holdings, Inc. | Inhibitors of rotamase enzyme activity effective at stimulating neuronal growth |
US6037370A (en) | 1995-06-08 | 2000-03-14 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5801197A (en) * | 1995-10-31 | 1998-09-01 | Gpi Nil Holdings, Inc. | Rotamase enzyme activity inhibitors |
US5801187A (en) | 1996-09-25 | 1998-09-01 | Gpi-Nil Holdings, Inc. | Heterocyclic esters and amides |
US5786378A (en) * | 1996-09-25 | 1998-07-28 | Gpi Nil Holdings, Inc. | Heterocyclic thioesters |
US5840736A (en) | 1996-11-13 | 1998-11-24 | Vertex Pharmaceuticals Incorporated | Methods and compositions for stimulating neurite growth |
US5780484A (en) | 1996-11-13 | 1998-07-14 | Vertex Pharmaceuticals Incorporated | Methods for stimulating neurite growth with piperidine compounds |
US5811434A (en) | 1996-11-13 | 1998-09-22 | Vertex Pharmacueticals Incorporated | Methods and compositions for stimulating neurite growth |
PA8442401A1 (es) | 1996-12-09 | 2000-05-24 | Guilford Pharm Inc | Inhibidores polipropilos de ciclofilina |
US5935989A (en) | 1996-12-31 | 1999-08-10 | Gpi Nil Holdings Inc. | N-linked ureas and carbamates of heterocyclic thioesters |
US5874449A (en) | 1996-12-31 | 1999-02-23 | Gpi Nil Holdings, Inc. | N-linked sulfonamides of heterocyclic thioesters |
US5721256A (en) | 1997-02-12 | 1998-02-24 | Gpi Nil Holdings, Inc. | Method of using neurotrophic sulfonamide compounds |
ZA98825B (en) | 1997-02-27 | 1998-10-19 | Guilford Pharm Inc | Method of using neurotrophic carbamates and ureas |
US5846979A (en) | 1997-02-28 | 1998-12-08 | Gpi Nil Holdings, Inc. | N-oxides of heterocyclic esters, amides, thioesters, and ketones |
-
1999
- 1999-07-15 CA CA002337377A patent/CA2337377A1/en not_active Abandoned
- 1999-07-15 AT AT99934043T patent/ATE268772T1/de not_active IP Right Cessation
- 1999-07-15 PL PL99345598A patent/PL345598A1/xx not_active Application Discontinuation
- 1999-07-15 DE DE69917907T patent/DE69917907T2/de not_active Expired - Fee Related
- 1999-07-15 EE EEP200100032A patent/EE200100032A/xx unknown
- 1999-07-15 SI SI9920067A patent/SI20638A/sl not_active IP Right Cessation
- 1999-07-15 ES ES99934043T patent/ES2226409T3/es not_active Expired - Lifetime
- 1999-07-15 HU HU0200637A patent/HUP0200637A3/hu unknown
- 1999-07-15 GE GE4273A patent/GEP20043368B/en unknown
- 1999-07-15 WO PCT/US1999/015965 patent/WO2000004020A1/en not_active Application Discontinuation
- 1999-07-15 KR KR1020017000654A patent/KR20010071920A/ko not_active Application Discontinuation
- 1999-07-15 DK DK99934043T patent/DK1098897T3/da active
- 1999-07-15 BR BR9912423-8A patent/BR9912423A/pt not_active Application Discontinuation
- 1999-07-15 SK SK46-2001A patent/SK462001A3/sk unknown
- 1999-07-15 EP EP99934043A patent/EP1098897B1/en not_active Expired - Lifetime
- 1999-07-15 IL IL14067699A patent/IL140676A0/xx unknown
- 1999-07-15 OA OA1200100015A patent/OA11581A/en unknown
- 1999-07-15 ID IDW20010130A patent/ID27428A/id unknown
- 1999-07-15 YU YU2901A patent/YU2901A/sh unknown
- 1999-07-15 AP APAP/P/2001/002052A patent/AP2001002052A0/en unknown
- 1999-07-15 CN CN99810848A patent/CN1318067A/zh active Pending
- 1999-07-15 JP JP2000560126A patent/JP2002520413A/ja not_active Withdrawn
- 1999-07-15 TR TR2001/00122T patent/TR200100122T2/xx unknown
- 1999-07-15 AU AU49963/99A patent/AU756912B2/en not_active Ceased
- 1999-07-15 PT PT99934043T patent/PT1098897E/pt unknown
- 1999-07-15 EA EA200100149A patent/EA200100149A1/ru unknown
- 1999-07-15 NZ NZ509211A patent/NZ509211A/xx unknown
- 1999-07-16 US US09/356,240 patent/US6630472B1/en not_active Expired - Fee Related
-
2001
- 2001-01-11 ZA ZA200100320A patent/ZA200100320B/en unknown
- 2001-01-12 IS IS5805A patent/IS5805A/is unknown
- 2001-01-12 NO NO20010191A patent/NO20010191L/no not_active Application Discontinuation
- 2001-02-15 LT LT2001012A patent/LT4850B/lt not_active IP Right Cessation
- 2001-02-16 HR HR20010118A patent/HRP20010118A2/hr not_active Application Discontinuation
- 2001-02-16 BG BG105268A patent/BG105268A/xx unknown
- 2001-03-13 LV LV010023A patent/LV12665B/lv unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NZ310339A (en) | Compositions for stimulating neurite growth comprising a neurotrophic amount of a compound with affinity for FKBP12 and a neurotrophic agent | |
MXPA02005510A (es) | Compuestos, composiciones y metodos para estimular el crecimiento y alargamiento neuronal. | |
CA2206824A1 (en) | Inhibitors of rotamase enzyme activity | |
AP9901518A0 (en) | Methods and compositions for stimulating neurite growth using compounds with affinity for FKBP12 in combination with neurotrophic factors. | |
WO2001036589A3 (en) | Human ex vivo immune system | |
WO1998025598A3 (en) | Methods and pharmaceutical compositions for inhibiting tumour cell growth | |
AU1505788A (en) | A method and a composition for treating neurological diseases such as migraine, by influencing the nerve cells | |
BRPI9611271A2 (pt) | inibidores de atividade de enzima rotamase | |
WO2000018801A3 (en) | Ncam binding compounds | |
BG105268A (en) | Compounds, compositions and methods for stimulating neuronal growth and elongation | |
WO2001042784A3 (en) | Methods for screening compounds active on neurons | |
CA2380943A1 (en) | Mechanically elongated neuronal cells and methods for producing and using these cells | |
EP0354323A3 (en) | Antidiabetic phosphates | |
WO1997014966B1 (en) | Method of activating a novel ligand regulatory pathway | |
WO2001028574A3 (en) | Methods for inducing in vivo proliferation and migration of transplanted progenitor cells in the brain | |
BR0210060A (pt) | Ligandos de fkbp de heterobiciclos | |
MX9709829A (es) | Metodos y composiciones para estimular el crecimiento de neurita. | |
EP1772517A3 (en) | DSP-3 dual specificity phosphatase | |
AR004113A1 (es) | Inhibidores de actividad de enzima rotamasa. | |
AU4210900A (en) | Products and methods for treating ptp lar related diseases | |
ECSP003800A (es) | Compuestos, composiciones y metodos para estimular el crecimiento y elongacion de neuronas |