BG104915A - Azabicyclic 5hti receptor ligands - Google Patents

Azabicyclic 5hti receptor ligands

Info

Publication number
BG104915A
BG104915A BG104915A BG10491500A BG104915A BG 104915 A BG104915 A BG 104915A BG 104915 A BG104915 A BG 104915A BG 10491500 A BG10491500 A BG 10491500A BG 104915 A BG104915 A BG 104915A
Authority
BG
Bulgaria
Prior art keywords
azabicyclic
receptor ligands
5hti
5hti receptor
compounds
Prior art date
Application number
BG104915A
Other languages
Bulgarian (bg)
English (en)
Inventor
Gene BRIGHT
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG104915A publication Critical patent/BG104915A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Gynecology & Obstetrics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Luminescent Compositions (AREA)
BG104915A 1998-04-09 2000-11-07 Azabicyclic 5hti receptor ligands BG104915A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8123798P 1998-04-09 1998-04-09
PCT/IB1999/000457 WO1999052907A1 (en) 1998-04-09 1999-03-18 Azabicyclic 5ht1 receptor ligands

Publications (1)

Publication Number Publication Date
BG104915A true BG104915A (en) 2001-07-31

Family

ID=22162936

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104915A BG104915A (en) 1998-04-09 2000-11-07 Azabicyclic 5hti receptor ligands

Country Status (41)

Country Link
US (2) US6525048B1 (xx)
EP (1) EP1070065B1 (xx)
JP (1) JP3496759B2 (xx)
KR (1) KR100378931B1 (xx)
CN (1) CN1117092C (xx)
AP (1) AP1175A (xx)
AR (1) AR015751A1 (xx)
AT (1) ATE248838T1 (xx)
AU (1) AU749254B2 (xx)
BG (1) BG104915A (xx)
BR (1) BR9909522A (xx)
CA (1) CA2327782A1 (xx)
CO (1) CO5080727A1 (xx)
CZ (1) CZ20003684A3 (xx)
DE (1) DE69910997T2 (xx)
DK (1) DK1070065T3 (xx)
DZ (1) DZ2756A1 (xx)
EA (1) EA003400B1 (xx)
ES (1) ES2204154T3 (xx)
HK (1) HK1035719A1 (xx)
HR (1) HRP20000653A2 (xx)
HU (1) HUP0102400A3 (xx)
ID (1) ID26086A (xx)
IL (1) IL138629A0 (xx)
IS (1) IS5641A (xx)
MA (1) MA26619A1 (xx)
MY (1) MY133390A (xx)
NO (1) NO20005004L (xx)
NZ (1) NZ507010A (xx)
OA (1) OA11496A (xx)
PA (1) PA8469101A1 (xx)
PE (1) PE20000413A1 (xx)
PL (1) PL343408A1 (xx)
PT (1) PT1070065E (xx)
SK (1) SK14782000A3 (xx)
TN (1) TNSN99056A1 (xx)
TR (1) TR200002932T2 (xx)
TW (1) TW555758B (xx)
WO (1) WO1999052907A1 (xx)
YU (1) YU59400A (xx)
ZA (1) ZA992596B (xx)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6231833B1 (en) 1999-08-05 2001-05-15 Pfizer Inc 2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
UA62015C2 (en) 1998-12-28 2003-12-15 Pfizer Prod Inc Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants)
EP1889614A3 (en) 1999-09-03 2010-09-22 APBI Holdings, LLC Methods of using rapid-onset selective serotonin reuptake inhibitors for treating sexual dysfunction
GB2362826A (en) * 2000-06-02 2001-12-05 Lilly Co Eli A pharmaceutical composition comprising a serotonin transport inhibitor and a serotonin recptor antagonist
ATE409475T1 (de) * 2001-02-20 2008-10-15 Dinan Timothy Gerard Behandlung von fibromyalgie mit pindolol
MXPA05009660A (es) * 2003-03-12 2005-10-20 Pfizer Prod Inc Derivados azabiciclicos de piridiloximetilo y bencisoxazol.
WO2005082370A1 (en) * 2004-01-29 2005-09-09 Pfizer Products Inc. Combinations of an atypical antipsychotic and an aminomethylpyridyloxymethyl/benzisoxazole azabicyclic derivatives for treating cns disorders
JP4559749B2 (ja) * 2004-02-16 2010-10-13 あすか製薬株式会社 ピペラジニルピリジン誘導体
AR049478A1 (es) 2004-03-25 2006-08-09 Solvay Pharm Bv Un procedimiento para la preparacion de 3-amino-8-(1-piperazinil)-2h-1-benzopiran-2-ona. sales e hidratos y composiciones farmaceuticas.
AR048112A1 (es) 2004-03-25 2006-03-29 Solvay Pharm Bv Derivados de 1-(2h-1-benzopiran-2-on-8-il)-piperazina para el tratamiento de dolor
CA2571555A1 (en) * 2004-06-22 2006-01-05 Pfizer Products Inc. Diazabicyclic histamine-3 receptor antagonists
EP2400300A1 (en) 2004-08-25 2011-12-28 Takeda Pharmaceutical Company Limited Method of screening preventives/remedies for stress urinary incontinence
BRPI0514793A (pt) * 2004-09-10 2008-06-24 Pfizer Prod Inc uso de derivados azabicìclicos de benzisoxazol e piridiloximetila na preparação de um medicamento para o tratamento de distúrbios cognitivos
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2020183011A1 (en) 2019-03-14 2020-09-17 Institut Curie Htr1d inhibitors and uses thereof in the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106849A (en) * 1988-05-24 1992-04-21 American Home Products Corporation Use of aryl- and heteroaryl piperazinyl carboxamides in the treatment of various central nervous system disorders
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
US5157034A (en) * 1991-02-27 1992-10-20 Pfizer Inc. Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
ES2096099T3 (es) * 1991-09-25 1997-03-01 Pfizer Perhidro-1h-pirido(1,2,a)pirazinas 2-sustituidas neurolepticas.
US5262428A (en) * 1992-03-13 1993-11-16 Wake Forest University Biologically active tropane derivatives
DK0646116T3 (da) * 1992-06-16 1999-12-27 Pfizer Fremgangsmåde og mellemprodukter til fremstilling af bis-aza-bicycliske anxiolytiske midler
GB9410512D0 (en) * 1994-05-25 1994-07-13 Smithkline Beecham Plc Novel treatment
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
US5614523A (en) * 1995-01-17 1997-03-25 Eli Lilly And Company Compounds having effects on serotonin-related systems

Also Published As

Publication number Publication date
KR100378931B1 (ko) 2003-04-07
AU3268799A (en) 1999-11-01
SK14782000A3 (sk) 2002-06-04
JP2002511469A (ja) 2002-04-16
US6887905B2 (en) 2005-05-03
DZ2756A1 (fr) 2003-09-15
CN1117092C (zh) 2003-08-06
NO20005004L (no) 2000-11-27
ATE248838T1 (de) 2003-09-15
BR9909522A (pt) 2000-12-19
AP9901502A0 (en) 1999-06-30
PA8469101A1 (es) 2000-09-29
OA11496A (en) 2004-05-14
AR015751A1 (es) 2001-05-16
CO5080727A1 (es) 2001-09-25
PL343408A1 (en) 2001-08-13
TNSN99056A1 (fr) 2005-11-10
CN1305477A (zh) 2001-07-25
AP1175A (en) 2003-06-04
DE69910997D1 (de) 2003-10-09
US20030181458A1 (en) 2003-09-25
DE69910997T2 (de) 2004-05-19
MY133390A (en) 2007-11-30
ID26086A (id) 2000-11-23
IL138629A0 (en) 2001-10-31
CZ20003684A3 (cs) 2002-03-13
EP1070065A1 (en) 2001-01-24
IS5641A (is) 2000-09-26
MA26619A1 (fr) 2004-12-20
ES2204154T3 (es) 2004-04-16
HRP20000653A2 (en) 2001-04-30
HK1035719A1 (en) 2001-12-07
KR20010042527A (ko) 2001-05-25
HUP0102400A3 (en) 2002-10-28
PT1070065E (pt) 2003-12-31
CA2327782A1 (en) 1999-10-21
JP3496759B2 (ja) 2004-02-16
NZ507010A (en) 2003-05-30
WO1999052907A1 (en) 1999-10-21
EA003400B1 (ru) 2003-04-24
TW555758B (en) 2003-10-01
DK1070065T3 (da) 2003-11-24
US6525048B1 (en) 2003-02-25
YU59400A (sh) 2003-10-31
AU749254B2 (en) 2002-06-20
EA200000910A1 (ru) 2001-04-23
TR200002932T2 (tr) 2001-01-22
PE20000413A1 (es) 2000-05-25
EP1070065B1 (en) 2003-09-03
HUP0102400A2 (hu) 2001-11-28
NO20005004D0 (no) 2000-10-04
ZA992596B (en) 2000-10-08

Similar Documents

Publication Publication Date Title
BG102704A (en) Fungicide 2-methoxybenzophenons
BG103485A (en) Ketobanzamides as calpain inhibitors
BG104915A (en) Azabicyclic 5hti receptor ligands
BG103310A (en) Benzonaphthyridins as bronchial therapeutical means
BG105557A (en) Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
GB9722520D0 (en) Compounds
CA2341291A1 (en) Pyridine ketones useful as herbicides
BG105784A (en) Triazole compounds with dopamine-d3-receptor affinity
TR200103273T2 (tr) Hemisentetik yöntem ve yeni bileşimler.
BG105028A (en) Bridged indenopyrrolocarbazoles
BG106340A (en) Substituted oxoazaheterocyclyl compounds
BG92804A (bg) 4-бензоилизоксазолови производни
MY132671A (en) Substituted 6,6-hetero-bicyclic derivatives
JO2654B1 (en) Multiple aryl caroxa amides are useful as lipid - lowering agents
WO2001017973A3 (de) Neue herbizide
CY2538B1 (en) Tetrahydropyrido compounds
MXPA02009549A (es) Imidazopiridinas triciclicas.
BG105847A (en) Calcilytic compounds
CA2356985A1 (en) 5ht1 antagonists for antidepressant therapy
IN187760B (xx)
BG101221A (en) N-substituted azabicycloheptane derivatives useful as neuroleptics
ES8502435A1 (es) Un metodo para preparar 2(1h)-piridinonas
CA2281702A1 (en) (4-piperidinyl)-1h-2-benzopyran derivatives useful as antipsychotic agents
GR3034406T3 (en) Intermediates for the preparation of 2-imidazoline-5-ones
PL343546A1 (en) Processes for preparing intermediates