BG104827A - 3',3'-n-bis-substituted macrolide lhrh antagonists - Google Patents

3',3'-n-bis-substituted macrolide lhrh antagonists

Info

Publication number
BG104827A
BG104827A BG104827A BG10482700A BG104827A BG 104827 A BG104827 A BG 104827A BG 104827 A BG104827 A BG 104827A BG 10482700 A BG10482700 A BG 10482700A BG 104827 A BG104827 A BG 104827A
Authority
BG
Bulgaria
Prior art keywords
bis
lhrh antagonists
substituted macrolide
substituted
compounds
Prior art date
Application number
BG104827A
Other languages
Bulgarian (bg)
English (en)
Inventor
Daryl Sauer
Fortuna Haviv
John Randolph
Nicholas MORT
Christopher DALTON
Milan Bruncko
Michele KAMINSKI
Bradley CRAWFORD
Lisa FREY
Jonathon Greer
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of BG104827A publication Critical patent/BG104827A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
BG104827A 1998-03-27 2000-10-05 3',3'-n-bis-substituted macrolide lhrh antagonists BG104827A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/049,458 US5972898A (en) 1998-03-27 1998-03-27 3',3-N-bis-substituted macrolide LHRH antagonists
PCT/US1999/006250 WO1999050276A1 (en) 1998-03-27 1999-03-22 3',3'-n-bis-substituted macrolide lhrh antagonists

Publications (1)

Publication Number Publication Date
BG104827A true BG104827A (en) 2001-07-31

Family

ID=21959914

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104827A BG104827A (en) 1998-03-27 2000-10-05 3',3'-n-bis-substituted macrolide lhrh antagonists

Country Status (18)

Country Link
US (1) US5972898A (sk)
EP (1) EP1066307A1 (sk)
JP (1) JP2002509938A (sk)
KR (1) KR20010034699A (sk)
CN (1) CN1303389A (sk)
AU (1) AU3197599A (sk)
BG (1) BG104827A (sk)
BR (1) BR9909121A (sk)
CA (1) CA2325519A1 (sk)
HU (1) HUP0102522A3 (sk)
IL (1) IL138220A0 (sk)
NO (1) NO20004807L (sk)
NZ (1) NZ506622A (sk)
PL (1) PL343152A1 (sk)
SK (1) SK13982000A3 (sk)
TR (1) TR200002766T2 (sk)
WO (1) WO1999050276A1 (sk)
ZA (1) ZA200005030B (sk)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
DK1267840T3 (da) * 2000-03-28 2009-09-07 Sandoz Ag Granulerede partikler med maskeret smag
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
KR100876538B1 (ko) 2000-08-17 2008-12-31 아에테르나 젠타리스 게엠베하 Ｌｈｒｈ 길항제의 염의 제조방법
JP5314835B2 (ja) 2000-11-15 2013-10-16 昌雄 菅又 子宮内膜症の予防又は治療薬
AU2003202115A1 (en) 2002-02-12 2003-09-04 Pfizer Inc. Non-peptide compounds affecting the action of gonadotropin-releasing hormone (gnrh)
MXPA04012566A (es) 2002-06-13 2005-04-19 Pfizer Agentes no peptidicos reguladores de la gnrh, composiciones farmaceuticas y procedimientos para su uso.
WO2007060518A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
CN102548986A (zh) 2009-06-05 2012-07-04 链接医药公司 氨基吡咯烷酮衍生物及其用途
AR085286A1 (es) * 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
DE3689758T2 (de) * 1985-08-31 1994-08-18 Kitasato Inst Erythromycinderivat und Verfahren zu dessen Herstellung.
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
KR0166096B1 (ko) * 1990-11-28 1999-01-15 우에하라 아키라 6-0-메틸에리쓰로마이신 a 유도체
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
HUP9903671A3 (en) * 1995-12-14 2001-11-28 Merck & Co Inc Antagonists of gonadotropin releasing hormone, pharmaceutical compositions and process for producing them
CZ351898A3 (cs) * 1996-05-07 1999-04-14 Abbott Laboratories 6-0-substituované erythromycinové sloučeniny a způsob jejich přípravy

Also Published As

Publication number Publication date
JP2002509938A (ja) 2002-04-02
NO20004807L (no) 2000-11-24
NZ506622A (en) 2003-03-28
EP1066307A1 (en) 2001-01-10
BR9909121A (pt) 2000-12-19
SK13982000A3 (sk) 2001-04-09
IL138220A0 (en) 2001-10-31
WO1999050276A1 (en) 1999-10-07
US5972898A (en) 1999-10-26
ZA200005030B (en) 2001-08-10
HUP0102522A3 (en) 2003-08-28
CA2325519A1 (en) 1999-10-07
AU3197599A (en) 1999-10-18
KR20010034699A (ko) 2001-04-25
NO20004807D0 (no) 2000-09-26
HUP0102522A2 (hu) 2001-10-28
CN1303389A (zh) 2001-07-11
PL343152A1 (en) 2001-07-30
TR200002766T2 (tr) 2001-01-22

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