HUP0102522A3 - 3',3'-n-bis-substituted macrolide lhrh antagonists and their use, process for their preparation and pharmaceutical compositions comprising them - Google Patents

3',3'-n-bis-substituted macrolide lhrh antagonists and their use, process for their preparation and pharmaceutical compositions comprising them

Info

Publication number
HUP0102522A3
HUP0102522A3 HU0102522A HUP0102522A HUP0102522A3 HU P0102522 A3 HUP0102522 A3 HU P0102522A3 HU 0102522 A HU0102522 A HU 0102522A HU P0102522 A HUP0102522 A HU P0102522A HU P0102522 A3 HUP0102522 A3 HU P0102522A3
Authority
HU
Hungary
Prior art keywords
bis
preparation
pharmaceutical compositions
lhrh antagonists
substituted macrolide
Prior art date
Application number
HU0102522A
Other languages
English (en)
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of HUP0102522A2 publication Critical patent/HUP0102522A2/hu
Publication of HUP0102522A3 publication Critical patent/HUP0102522A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HU0102522A 1998-03-27 1999-03-22 3',3'-n-bis-substituted macrolide lhrh antagonists and their use, process for their preparation and pharmaceutical compositions comprising them HUP0102522A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/049,458 US5972898A (en) 1998-03-27 1998-03-27 3',3-N-bis-substituted macrolide LHRH antagonists
PCT/US1999/006250 WO1999050276A1 (en) 1998-03-27 1999-03-22 3',3'-n-bis-substituted macrolide lhrh antagonists

Publications (2)

Publication Number Publication Date
HUP0102522A2 HUP0102522A2 (hu) 2001-10-28
HUP0102522A3 true HUP0102522A3 (en) 2003-08-28

Family

ID=21959914

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102522A HUP0102522A3 (en) 1998-03-27 1999-03-22 3',3'-n-bis-substituted macrolide lhrh antagonists and their use, process for their preparation and pharmaceutical compositions comprising them

Country Status (18)

Country Link
US (1) US5972898A (hu)
EP (1) EP1066307A1 (hu)
JP (1) JP2002509938A (hu)
KR (1) KR20010034699A (hu)
CN (1) CN1303389A (hu)
AU (1) AU3197599A (hu)
BG (1) BG104827A (hu)
BR (1) BR9909121A (hu)
CA (1) CA2325519A1 (hu)
HU (1) HUP0102522A3 (hu)
IL (1) IL138220A0 (hu)
NO (1) NO20004807L (hu)
NZ (1) NZ506622A (hu)
PL (1) PL343152A1 (hu)
SK (1) SK13982000A3 (hu)
TR (1) TR200002766T2 (hu)
WO (1) WO1999050276A1 (hu)
ZA (1) ZA200005030B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6387885B1 (en) * 1998-08-26 2002-05-14 Abbott Laboratories 3′,3′-N-bis-desmethyl-3′-N-cycloalkyl erythromycin derivatives as LHRH antagonists
DE60138876D1 (de) * 2000-03-28 2009-07-16 Sandoz Ag Geschmackmaskierte granulierte teilchen
EP1146051A3 (en) * 2000-04-10 2001-10-31 Pfizer Products Inc. Erythromycin A derivatives
KR100876538B1 (ko) 2000-08-17 2008-12-31 아에테르나 젠타리스 게엠베하 Ｌｈｒｈ 길항제의 염의 제조방법
JP5314835B2 (ja) 2000-11-15 2013-10-16 昌雄 菅又 子宮内膜症の予防又は治療薬
AU2003202115A1 (en) 2002-02-12 2003-09-04 Pfizer Inc. Non-peptide compounds affecting the action of gonadotropin-releasing hormone (gnrh)
JP2005538064A (ja) 2002-06-13 2005-12-15 ファイザー・インク 非ペプチドＧｎＲＨ剤、医薬組成物、およびそれらの使用方法
WO2007060518A2 (en) * 2005-11-23 2007-05-31 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
AU2010256360A1 (en) 2009-06-05 2012-01-12 Astrazeneca Ab Aminopyrrolidinone derivatives and uses thereof
AR085286A1 (es) * 2011-02-21 2013-09-18 Taisho Pharmaceutical Co Ltd Derivado de macrolido sustituido en la posicion c-4

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6187625A (ja) * 1984-10-05 1986-05-06 Satoshi Omura 消化管収縮運動促進剤
EP0215355B1 (en) * 1985-08-31 1994-04-06 Kitasato Kenkyusho Erythromycin derivative and process for preparing the same
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US4920102A (en) * 1988-04-18 1990-04-24 Eli Lilly And Company Method for treating gastrointestinal disorders
IL114589A (en) * 1990-11-21 1999-12-22 Roussel Uclaf Intermediates for the preparation of the history of erythromycin
DE69127457T2 (de) * 1990-11-28 1998-01-22 Taisho Pharmaceutical Co., Ltd., Tokio/Tokyo 6-0-methylerythromycin a-derivat
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
PL327146A1 (en) * 1995-12-14 1998-11-23 Merck & Co Inc Antagonists of the gonadotrophin liberating hormone
CZ351898A3 (cs) * 1996-05-07 1999-04-14 Abbott Laboratories 6-0-substituované erythromycinové sloučeniny a způsob jejich přípravy

Also Published As

Publication number Publication date
SK13982000A3 (sk) 2001-04-09
PL343152A1 (en) 2001-07-30
TR200002766T2 (tr) 2001-01-22
KR20010034699A (ko) 2001-04-25
WO1999050276A1 (en) 1999-10-07
NO20004807D0 (no) 2000-09-26
BG104827A (en) 2001-07-31
CA2325519A1 (en) 1999-10-07
US5972898A (en) 1999-10-26
ZA200005030B (en) 2001-08-10
BR9909121A (pt) 2000-12-19
CN1303389A (zh) 2001-07-11
NO20004807L (no) 2000-11-24
AU3197599A (en) 1999-10-18
NZ506622A (en) 2003-03-28
EP1066307A1 (en) 2001-01-10
IL138220A0 (en) 2001-10-31
HUP0102522A2 (hu) 2001-10-28
JP2002509938A (ja) 2002-04-02

Similar Documents

Publication Publication Date Title
HUP0300207A3 (en) 1,2,3,4-tetrahydroisquinoline derivatives, pharmaceutical compositions containing them and their preparation processes
HUP0203542A3 (en) 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
IL138280A0 (en) 20-KETO-11β-ARYLSTERIODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THE PREPARATION THEREOF
HUP0302969A3 (en) Npyy5 antagonists, pharmaceutical compositions containing them and their use
IL123648A0 (en) 1,4-Benzothiazepine-1,1-dioxides their preparation and pharmaceutical compositions containing them
IL123986A0 (en) Antithombotic agents process for their preparation and pharmaceutical compositions comprising them
HU227841B1 (en) 2-phenyl substituted imidazotriazinones, process for their preparation and pharmaceutical compositions thereof
HUP0001508A3 (en) 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
HUP0103884A3 (en) Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use
HUP0001555A3 (en) Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
HUP0102512A3 (en) Bridged indenopyrrolocarbazoles, process for their preparation, pharmaceutical compositions containing them and their use
PL349448A1 (en) Benzopyrans and benzoxepines, pharmaceutical compositions comprising them and preparation process
HUP0102515A3 (en) Cyclopeptides, process for their preparation, pharmaceutical compositions comprising thereof and their use
HUP0002272A3 (en) Aroyl-piperazine derivatives, their preparation pharmaceutical compositions containing them and their use
HUP0102215A3 (en) Benzoylpyridazines, pharmaceutical compositions containing the same and process for their preparation
HUP0201402A3 (en) Bis-sulfonamides, process for their preparation and pharmaceutical compositions containing them
HUP0200363A2 (en) Lhrh antagonist decapeptides, pharmaceutical compositions comprising thereof and processes for their preparation
HUP0105075A3 (en) 3,3-biarylpiperidine and 2,2-biarylmorpholine derivatives, their use and pharmaceutical compositions containing them
HK1039122A1 (zh) 取代的6-苄基-4-氧代嘧啶，其製備方法以及含該化合物的藥物組合物
HUP0302193A3 (en) 1,4-diazabicyclo[3.2.2]nonabenzoxazole, -benzothiazole and benzimidazole derivatives, preparation thereof and pharmaceutical compositions containing them
HUP0202624A3 (en) Pyrazolo[4,3-d]pyrimidine-derivatives, process for their preparation, pharmaceutical compositions containing them and their use
HUP0003577A3 (en) Tetrahydro gamma-carbolines, process for their preparation, their use and pharmaceutical compositions containing them
HUP0002650A3 (en) 4-oxo-3,5-dihydro-4h-pyridazino[4,5-b]-indole-1-acetamide derivatives, process for their preparation and pharmaceutical compositions containing them
HUP0102522A3 (en) 3',3'-n-bis-substituted macrolide lhrh antagonists and their use, process for their preparation and pharmaceutical compositions comprising them
HUP0203627A3 (en) N-guanidinoalkylamides, their preparation, their use, and pharmaceutical compositions comprising them

Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees