BG104604A - Метод за получаване на пароксетин хидрохлорид - Google Patents

Метод за получаване на пароксетин хидрохлорид

Info

Publication number
BG104604A
BG104604A BG104604A BG10460400A BG104604A BG 104604 A BG104604 A BG 104604A BG 104604 A BG104604 A BG 104604A BG 10460400 A BG10460400 A BG 10460400A BG 104604 A BG104604 A BG 104604A
Authority
BG
Bulgaria
Prior art keywords
preparation
hydrochloride
propan
paroxetin
paroxetine hydrochloride
Prior art date
Application number
BG104604A
Other languages
English (en)
Inventor
Neal Ward
Alan Jones
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of BG104604A publication Critical patent/BG104604A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Изобретението се отнася до метод за получаване напароксетин хидрохлорид пропан-2-ол солват. По метода се получава разтвор на пароксетин хидрохлорид в смес от пропан-2-ол и ефективен съразтворител, след което пароксетин хидрохлорид пропан-2-ол солватът се кристализира от разтвора.
BG104604A 1997-12-19 2000-07-13 Метод за получаване на пароксетин хидрохлорид BG104604A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9726907.0A GB9726907D0 (en) 1997-12-19 1997-12-19 Novel compounds
PCT/GB1998/003836 WO1999032484A1 (en) 1997-12-19 1998-12-18 Process for the preparation of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
BG104604A true BG104604A (bg) 2001-03-30

Family

ID=10823933

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104604A BG104604A (bg) 1997-12-19 2000-07-13 Метод за получаване на пароксетин хидрохлорид

Country Status (20)

Country Link
EP (1) EP1042318A1 (bg)
JP (1) JP2001526288A (bg)
KR (1) KR20010033317A (bg)
CN (1) CN1281448A (bg)
AP (1) AP2000001836A0 (bg)
AU (1) AU1769899A (bg)
BG (1) BG104604A (bg)
BR (1) BR9813638A (bg)
CA (1) CA2315066A1 (bg)
EA (1) EA200000689A1 (bg)
GB (1) GB9726907D0 (bg)
HU (1) HUP0004503A3 (bg)
ID (1) ID24733A (bg)
IL (1) IL136590A0 (bg)
NO (1) NO20003145L (bg)
OA (1) OA11635A (bg)
PL (1) PL341358A1 (bg)
SK (1) SK9242000A3 (bg)
TR (1) TR200001933T2 (bg)
WO (1) WO1999032484A1 (bg)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9919001D0 (en) * 1999-08-12 1999-10-13 Smithkline Beecham Plc Novel process
GB9923439D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
NL1017421C2 (nl) 2001-02-21 2002-01-15 Synthon Bv Werkwijze voor het vervaardigen van paroxetine.
EP1482939A4 (en) * 2002-02-22 2005-10-12 Teva Pharma PREPARATION OF PAROXETIN WITH NEW INTERMEDIATE PRODUCTS
KR100672184B1 (ko) 2004-09-21 2007-01-19 주식회사종근당 파록세틴의 콜린산 또는 콜린산 유도체 염

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058061T3 (es) * 1985-10-25 1994-11-01 Beecham Group Plc Derivado de piperidina, su preparacion y su uso como medicamento.
AR001982A1 (es) * 1995-02-06 1998-01-07 Smithkline Beecham Plc Clorhidrato de paroxetina anhidratado, y procedimiento para su preparacion
CA2187128A1 (en) * 1996-10-04 1997-06-26 K. S. Keshava Murthy New and useful polymorph of anhydrous paroxetine hydrochloride

Also Published As

Publication number Publication date
KR20010033317A (ko) 2001-04-25
AP2000001836A0 (en) 2000-06-30
JP2001526288A (ja) 2001-12-18
HUP0004503A3 (en) 2002-04-29
EA200000689A1 (ru) 2000-12-25
CN1281448A (zh) 2001-01-24
CA2315066A1 (en) 1999-07-01
ID24733A (id) 2000-08-03
BR9813638A (pt) 2000-10-17
NO20003145D0 (no) 2000-06-16
GB9726907D0 (en) 1998-02-18
WO1999032484A1 (en) 1999-07-01
HUP0004503A2 (hu) 2002-03-28
OA11635A (en) 2004-11-22
NO20003145L (no) 2000-06-16
SK9242000A3 (en) 2001-01-18
TR200001933T2 (tr) 2000-12-21
EP1042318A1 (en) 2000-10-11
IL136590A0 (en) 2001-06-14
PL341358A1 (en) 2001-04-09
AU1769899A (en) 1999-07-12

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